Rif1 Controls DNA replication timing in yeast through the PP1 Phosphatase Glc7

Cell Reports

Volumn 7, Issue 1, 2014, Pages 62-69

  Mattarocci, Stefano ^a   Shyian, Maksym ^a   Lemmens, Laure ^a   Damay, Pascal ^a   Altintas, Dogus Murat ^a   Shi, Tianlai ^b,d   Bartholomew, Clinton R ^c   Thomä, Nicolas H ^b   Hardy, Christopher F J ^c   Shore, David ^a  

^a UNIVERSITY OF GENEVA   (Switzerland)

^b FRIEDRICH MIESCHER INSTITUTE FOR BIOMEDICAL RESEARCH   (Switzerland)

^c VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d F HOFFMANN LA ROCHE LTD   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

ADAPTOR PROTEIN; DBF4 DEPENDENT KINASE; GLC7 PROTEIN; MINICHROMOSOME MAINTENANCE PROTEIN 4; PHOSPHOPROTEIN PHOSPHATASE 1; PHOSPHOTRANSFERASE; PROTEIN RIF1; SLD3 PROTEIN; TELOMERE BINDING PROTEIN; UNCLASSIFIED DRUG; CDC7 PROTEIN, S CEREVISIAE; CELL CYCLE PROTEIN; GLC7 PROTEIN, S CEREVISIAE; PROTEIN BINDING; PROTEIN SERINE THREONINE KINASE; REPRESSOR PROTEIN; RIF1 PROTEIN, S CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEIN;

AMINO TERMINAL SEQUENCE; ARTICLE; BINDING AFFINITY; COMPLEX FORMATION; CONTROLLED STUDY; DNA REPLICATION; ENZYME PHOSPHORYLATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN MOTIF; PROTEIN PROTEIN INTERACTION; TELOMERE; YEAST; ANIMAL; DNA REPLICATION ORIGIN; GENETICS; METABOLISM; PHOSPHORYLATION; PHYSIOLOGY; SACCHAROMYCES CEREVISIAE;

METAZOA; SACCHAROMYCETALES;

ANIMALS; CELL CYCLE PROTEINS; DNA REPLICATION; PHOSPHORYLATION; PROTEIN BINDING; PROTEIN PHOSPHATASE 1; PROTEIN-SERINE-THREONINE KINASES; REPLICATION ORIGIN; REPRESSOR PROTEINS; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS; TELOMERE; TELOMERE-BINDING PROTEINS;

EID: 84898041281     PISSN: None     EISSN: 22111247     Source Type: Journal    
DOI: 10.1016/j.celrep.2014.03.010     Document Type: Article

References (36)

1. Aparicio O.M. Location, location, location: it's all in the timing for replication origins. Genes Dev. 2013, 27:117-128.
2. Araki H. Initiation of chromosomal DNA replication in eukaryotic cells; contribution of yeast genetics to the elucidation. Genes Genet. Syst. 2011, 86:141-149.
3. Bianchi A., Shore D. Early replication of short telomeres in budding yeast. Cell 2007, 128:1051-1062.
4. Bianchi A., Negrini S., Shore D. Delivery of yeast telomerase to a DNA break depends on the recruitment functions of Cdc13 and Est1. Mol. Cell 2004, 16:139-146.
5. Breitkreutz A., Choi H., Sharom J.R., Boucher L., Neduva V., Larsen B., Lin Z.Y., Breitkreutz B.J., Stark C., Liu G., et al. A global protein kinase and phosphatase interaction network in yeast. Science 2010, 328:1043-1046.
6. Cannon J.F. Function of protein phosphatase-1, Glc7, in Saccharomyces cerevisiae. Adv. Appl. Microbiol. 2010, 73:27-59.
7. Chen S., Bell S.P. CDK prevents Mcm2-7 helicase loading by inhibiting Cdt1 interaction with Orc6. Genes Dev. 2011, 25:363-372.
8. Cornacchia D., Dileep V., Quivy J.P., Foti R., Tili F., Santarella-Mellwig R., Antony C., Almouzni G., Gilbert D.M., Buonomo S.B. Mouse Rif1 is a key regulator of the replication-timing programme in mammalian cells. EMBO J. 2012, 31:3678-3690.
9. Cosgrove A.J., Nieduszynski C.A., Donaldson A.D. Ku complex controls the replication time of DNA in telomere regions. Genes Dev. 2002, 16:2485-2490.
10. Davé A., Cooley C., Garg M., Bianchi A. Protein phosphatase 1 recruitment by Rif1 regulates DNA replication origin firing by counteracting DDK activity. Cell Rep 2014, Published online April 10, 2014. 10.1016/j.celrep.2014.02.019.
11. Donaldson A.D. Shaping time: chromatin structure and the DNA replication programme. Trends Genet. 2005, 21:444-449.
12. Hardy C.F.J., Sussel L., Shore D. A RAP1-interacting protein involved in transcriptional silencing and telomere length regulation. Genes Dev. 1992, 6:801-814.
13. Hayano M., Kanoh Y., Matsumoto S., Renard-Guillet C., Shirahige K., Masai H. Rif1 is a global regulator of timing of replication origin firing in fission yeast. Genes Dev. 2012, 26:137-150.
14. Heller R.C., Kang S., Lam W.M., Chen S., Chan C.S., Bell S.P. Eukaryotic origin-dependent DNA replication invitro reveals sequential action of DDK and S-CDK kinases. Cell 2011, 146:80-91.
15. Hendrickx A., Beullens M., Ceulemans H., Den Abt T., Van Eynde A., Nicolaescu E., Lesage B., Bollen M. Docking motif-guided mapping of the interactome of protein phosphatase-1. Chem. Biol. 2009, 16:365-371.
16. Hiraga S., Alvino G.M., Chang F., Lian H.Y., Sridhar A., Kubota T., Brewer B.J., Weinreich M., Raghuraman M.K., Donaldson A.D. Rif1 controls DNA replication by directing protein phosphatase 1 to reverse Cdc7-mediated phosphorylation of the MCM complex. Genes Dev. 2014, 28:372-383.
17. James P., Halladay J., Craig E.A. Genomic libraries and a host strain designed for highly efficient two-hybrid selection in yeast. Genetics 1996, 144:1425-1436.
18. Labib K. How do Cdc7 and cyclin-dependent kinases trigger the initiation of chromosome replication in eukaryotic cells?. Genes Dev. 2010, 24:1208-1219.
19. Lempiäinen H., Uotila A., Urban J., Dohnal I., Ammerer G., Loewith R., Shore D. Sfp1 interaction with TORC1 and Mrs6 reveals feedback regulation on TOR signaling. Mol. Cell 2009, 33:704-716.
20. Lian H.Y., Robertson E.D., Hiraga S., Alvino G.M., Collingwood D., McCune H.J., Sridhar A., Brewer B.J., Raghuraman M.K., Donaldson A.D. The effect of Ku on telomere replication time is mediated by telomere length but is independent of histone tail acetylation. Mol. Biol. Cell 2011, 22:1753-1765.
21. Lopez-Mosqueda J., Maas N.L., Jonsson Z.O., Defazio-Eli L.G., Wohlschlegel J., Toczyski D.P. Damage-induced phosphorylation of Sld3 is important to block late origin firing. Nature 2010, 467:479-483.
22. Mantiero D., Mackenzie A., Donaldson A., Zegerman P. Limiting replication initiation factors execute the temporal programme of origin firing in budding yeast. EMBO J. 2011, 30:4805-4814.
23. Mishra K., Shore D. Yeast Ku protein plays a direct role in telomeric silencing and counteracts inhibition by rif proteins. Curr. Biol. 1999, 9:1123-1126.
24. Moorhead G.B., Trinkle-Mulcahy L., Nimick M., De Wever V., Campbell D.G., Gourlay R., Lam Y.W., Lamond A.I. Displacement affinity chromatography of protein phosphatase one (PP1) complexes. BMC Biochem. 2008, 9:28.
25. Rhind N., Yang S.C., Bechhoefer J. Reconciling stochastic origin firing with defined replication timing. Chromosome Res. 2010, 18:35-43.
26. Rose M.D., Winston F., Hieter P. Methods in Yeast Genetics: A Laboratory Course Manual 1990, Cold Spring Harbor Press, Plainview, New York.
27. Sheu Y.J., Stillman B. Cdc7-Dbf4 phosphorylates MCM proteins via a docking site-mediated mechanism to promote S phase progression. Mol. Cell 2006, 24:101-113.
28. Shi T., Bunker R.D., Mattarocci S., Ribeyre C., Faty M., Gut H., Scrima A., Rass U., Rubin S.M., Shore D., Thomä N.H. Rif1 and Rif2 shape telomere function and architecture through multivalent Rap1 interactions. Cell 2013, 153:1340-1353.
29. Siddiqui K., On K.F., Diffley J.F. Regulating DNA replication in eukarya. Cold Spring Harb. Perspect. Biol. 2013, 5. pii: a012930.
30. Sreesankar E., Senthilkumar R., Bharathi V., Mishra R.K., Mishra K. Functional diversification of yeast telomere associated protein, Rif1, in higher eukaryotes. BMC Genomics 2012, 13:255.
31. Stevenson J.B., Gottschling D.E. Telomeric chromatin modulates replication timing near chromosome ends. Genes Dev. 1999, 13:146-151.
32. Tanaka S., Umemori T., Hirai K., Muramatsu S., Kamimura Y., Araki H. CDK-dependent phosphorylation of Sld2 and Sld3 initiates DNA replication in budding yeast. Nature 2007, 445:328-332.
33. Tanaka S., Nakato R., Katou Y., Shirahige K., Araki H. Origin association of Sld3, Sld7, and Cdc45 proteins is a key step for determination of origin-firing timing. Curr. Biol. 2011, 21:2055-2063.
34. Yamazaki S., Ishii A., Kanoh Y., Oda M., Nishito Y., Masai H. Rif1 regulates the replication timing domains on the human genome. EMBO J. 2012, 31:3667-3677.
35. Zegerman P., Diffley J.F. Phosphorylation of Sld2 and Sld3 by cyclin-dependent kinases promotes DNA replication in budding yeast. Nature 2007, 445:281-285.
36. Zegerman P., Diffley J.F. Checkpoint-dependent inhibition of DNA replication initiation by Sld3 and Dbf4 phosphorylation. Nature 2010, 467:474-478.