Midlife measurements of white matter microstructure predict subsequent regional white matter atrophy in healthy adults

Human Brain Mapping

Volumn 35, Issue 5, 2014, Pages 2044-2054

  Ly, Martina ^a,b,c   Canu, Elisa ^d   Xu, Guofan ^a,b   Oh, Jennifer ^a,b   Mclaren, Donald G ^e,f,g   Dowling, N Maritza ^a,b   Alexander, Andrew L ^b,h   Sager, Mark A ^a,b   Johnson, Sterling C ^a,b   Bendlin, Barbara B ^a,b  

^a WILLIAM S MIDDLETON MEMORIAL VETERANS HOSPITAL   (United States)

^b UNIVERSITY OF WISCONSIN SCHOOL OF MEDICINE AND PUBLIC HEALTH   (United States)

^c UNIVERSITY OF WISCONSIN MADISON   (United States)

^d IRCCS ISTITUTO CENTRO SAN GIOVANNI DI DIO FATEBENEFRATELLI   (Italy)

^e HARVARD MEDICAL SCHOOL   (United States)

^f MASSACHUSETTS GENERAL HOSPITAL   (United States)

^g VETERANS AFFAIRS MEDICAL CENTER   (United States)

^h UNIVERSITY OF WISCONSIN MADISON   (United States)

Author keywords

Aging; Atrophy; Diffusion tensor imaging; Fractional anisotropy; Longitudinal; Microstructure; Tensor based morphometry

Indexed keywords

ADULT; AGE; AGING; ANATOMICAL CONCEPTS; ANTERIOR CORONA RADIATA; ARTICLE; BRAIN ATROPHY; BRAIN REGION; BRAIN SIZE; CARDIAC GATED IMAGING; CEREBELLAR REGION; CINGULUM REGION; CONTROLLED STUDY; CORPUS CALLOSUM; DIAGNOSTIC TEST ACCURACY STUDY; DIFFUSION TENSOR IMAGING; DIFFUSION WEIGHTED IMAGING; ECHO PLANAR IMAGING; ENTORHINAL WHITE MATTER; FEMALE; FOLLOW UP; FRACTIONAL ANISOTROPY; FRONTAL REGION; GENU REGION; GRAY MATTER; HUMAN; HUMAN EXPERIMENT; IN VIVO STUDY; INFERIOR TEMPORAL GYRUS; LONGITUDINAL STUDY; MALE; MIDDLE AGED; MIDLIFE PERIOD; MORPHOMETRICS; NEUROIMAGING; NORMAL HUMAN; NUCLEAR MAGNETIC RESONANCE SCANNER; PREDICTION; PREDICTIVE VALUE; PREDICTOR VARIABLE; PRIORITY JOURNAL; SPATIAL ANALYSIS; SPLENIUM REGION; STRUCTURE ANALYSIS; SUPERIOR LONGITUDINAL BUNDLE; TEMPORAL LOBE; TEMPORAL STEM REGION; TENSOR BASED MORPHOMETRY; TISSUE STRUCTURE; WHITE MATTER; WHITE MATTER ATROPHY; WHITE MATTER CONTRACTION; WHITE MATTER MICROSTRUCTURE; AGED; ANISOTROPY; ATROPHY; BRAIN; BRAIN MAPPING; GENETICS; LEUKOENCEPHALOPATHIES; PATHOLOGY;

APOLIPOPROTEIN E4;

ADULT; AGED; ANISOTROPY; APOLIPOPROTEIN E4; ATROPHY; BRAIN; BRAIN MAPPING; DIFFUSION MAGNETIC RESONANCE IMAGING; DIFFUSION TENSOR IMAGING; FEMALE; HUMANS; LEUKOENCEPHALOPATHIES; MALE; MIDDLE AGED;

EID: 84898036506     PISSN: 10659471     EISSN: 10970193     Source Type: Journal    
DOI: 10.1002/hbm.22311     Document Type: Article

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