Matrine cooperates with all-trans retinoic acid on differentiation induction of all-trans retinoic acid-resistant acute promyelocytic leukemia cells (NB4-LR1): Possible mechanisms

Planta Medica

Volumn 80, Issue 5, 2014, Pages 399-408

  Wu, Dijiong ^a   Shao, Keding ^a   Sun, Jie ^b   Zhu, Fuyun ^c   Ye, Baodong ^a   Liu, Tingting ^b   Shen, Yiping ^a   Huang, He ^b   Zhou, Yuhong ^a  

^a ZHEJIANG PROVINCIAL PEOPLE'S HOSPITAL   (China)

^b ZHEJIANG UNIVERSITY   (China)

^c ZHEJIANG CHINESE MEDICAL UNIVERSITY   (China)

Author keywords

acute promyelocytic leukemia; all trans retinoic acid; cellular differentiation; Fabaceae; matrine; retinoic acid resistant; Sophora flavescens

Indexed keywords

CD11B ANTIGEN; CYCLIC AMP; CYCLIC AMP DEPENDENT PROTEIN KINASE; DNA TOPOISOMERASE (ATP HYDROLYSING); HYBRID PROTEIN; MATRINE; NITROBLUE TETRAZOLIUM; RETINOIC ACID; RETINOIC ACID RECEPTOR ALPHA; ALKALOID; PRIMER DNA; QUINOLIZINE DERIVATIVE;

ARTICLE; CELL DIFFERENTIATION; CELL MATURATION; CELL NUCLEUS; CELL SHAPE; CELL STRUCTURE; CONTROLLED STUDY; DOWN REGULATION; ENZYME ACTIVITY; FUSION GENE; GENE EXPRESSION; IN VITRO STUDY; LEUKEMIA CELL LINE; PROMYELOCYTIC LEUKEMIA; PROTEIN EXPRESSION; SOPHORA FLAVESCENS; DRUG EFFECTS; DRUG POTENTIATION; HUMAN; NUCLEOTIDE SEQUENCE; PATHOLOGY; POLYMERASE CHAIN REACTION; TUMOR CELL LINE;

FABACEAE; SOPHORA FLAVESCENS;

ALKALOIDS; BASE SEQUENCE; CELL DIFFERENTIATION; CELL LINE, TUMOR; DNA PRIMERS; DRUG SYNERGISM; HUMANS; LEUKEMIA, PROMYELOCYTIC, ACUTE; POLYMERASE CHAIN REACTION; QUINOLIZINES; TRETINOIN;

EID: 84898022740     PISSN: 00320943     EISSN: 14390221     Source Type: Journal    
DOI: 10.1055/s-0034-1368183     Document Type: Article

References (35)

1. Adès L., Guerci A., Raffoux E., Sanz M., Chevallier P., Lapusan S., Recher C., Thomas X., Rayon C., Castaigne S., Tournilhac O., de Botton S., Ifrah N., Cahn J. Y., Solary E., Gardin C., Fegeux N., Bordessoule D., Ferrant A., Meyer-Monard S., Vey N., Dombret H., Degos L., Chevret S., Fenaux P. European APL Group Very long-term outcome of acute promyelocytic leukemia after treatment with all-trans retinoic acid and chemotherapy: the European APL Group experience. Blood: 2010; 115 1690 1696
2. Fenaux P., Wang Z. Z., Degos L. Treatment of acute promyelocytic leukemia by retinoids. Curr Top Microbiol Immunol: 2007; 313 101 128 (Pubitemid 47400335)
3. Au W. Y., Kumana C. R., Lee H. K., Lin S. Y., Liu H., Yeung D. Y., Lau J. S., Kwong Y. L. Oral arsenic trioxide-based maintenance regimens for first complete remission of acute promyelocytic leukemia: a 10-year follow-up study. Blood: 2011; 118 6535 6543
4. Long Y., Lin X. T., Zeng K. L., Zhang L. Efficacy of intramuscular matrine in the treatment of chronic hepatitis B. Hepatobiliary Pancreat Dis Int: 2004; 3 69 72 (Pubitemid 38256128)
5. Yang Z. S., Chen J. B., Zhang H. B., Hu N. N., Wang X. Therapeutic effect of matrine glucose injection combined with CHOP on non-Hodgkin?s lymphoma. Chin Tradit Pat Med: 2007; 29 1728 1730
6. Wu D. J., Shao K. D., Sun J., Ye B. D., Zhou Y. H. Clinical and experimental advance of matrine in the treatment of hematologic malignancies. J Clin Hematol (China): 2012; 25 469 471
7. Fang H. Y., Wu D. J., Shen Y. P. Efficacy of compound matrine injection combined with MPR in the treatment of Multiple Myeloma. Zhejiang JITCWM (China): 2012; 22 109 111
8. Zhang Y., Dong Z., Jin L., Zhang K., Zhao X., Fu J., Gong Y., Sun M., Yang B., Li B. Arsenic trioxide-induced hERG K(+) channel deficiency can be rescued by matrine and oxymatrine through up-regulating transcription factor Sp1 expression. Biochem Pharmacol: 2013; 85 59 68
9. Zhang S., Zhang Y., Zhuang Y., Wang J., Ye J., Zhang S., Wu J., Yu K., Han Y. Matrine induces apoptosis in human acute myeloid leukemia cells via the mitochondrial pathway and Akt inactivation. PLoS One: 2012; 7 e46853
10. Zhang W., Dai B. T., Xu Y. H. Effects of matrine on invasion and metastasis of leukemia cell line Jurkat. CJITWM (China): 2008; 28 907 911
11. Zhang L. P., Jiang J. K., Tam J. W., Zhang Y., Liu X. S., Xu X. R., Liu B. Z., He Y. J. Effects of Matrine on proliferation and differentiation in K-562 cells. Leuk Res: 2001; 25 793 800 (Pubitemid 32734092)
12. Wu D. J., Zhou Y. H., Zhu J., Zhao W., Zhong W. J., Wang Z., Qian H., Li R., Fu S., Sun J. Study on matrine alleviating retinoic acid resistance in acute promyelocytic leukemia. Chin J Hematol: 2011; 32 313 316
13. Zhu Q., Yu Y., Jia P. M., Cai X., Chen S. J., Chen Z., Wang Z. Y., Tong J. H. In vitro study of the effects of arsenic trioxide combined with 8-CPT-cAMP on differentiation induction in retinoic acid resistant acute promyelocytic leukemia cells. Chin J Hematol: 2003; 24 6 9
14. Hirashima K., Migita T., Sato S., Muramatsu Y., Ishikawa Y., Seimiya H. Telomere length influences cancer cell differentiation in vivo. Mol Cell Biol: 2013; 33 2988 2995
15. Georgopoulos N. T., Kirkwood L. A., Varley C. L., MacLaine N. J., Aziz N., Southgate J. Immortalisation of normal human urothelial cells compromises differentiation capacity. Eur Urol: 2011; 60 141 149
16. He P., Liu Y., Zhang M., Wang X., Xi J., Wu D., Li J., Cao Y. Interferon- γ enhances promyelocytic leukemia protein expression in acute promyelocytic cells and cooperates with all-trans-retinoic acid to induce maturation of NB4 and NB4-LR1 cells. Exp Ther Med: 2012; 3 776 780
17. Xu D. R., Huang S., Long Z. J., Chen J. J., Zou Z. Z., Li J., Lin D. J., Liu Q. Inhibition of mitotic kinase Aurora suppresses Akt-1 activation and induces apoptotic cell death in all-trans retinoid acid-resistant acute promyelocytic leukemia cells. J Transl Med: 2011; 9 74
18. Sato T., Okumura F., Iguchi A., Ariga T., Hatakeyama S. TRIM32 promotes retinoic acid receptor α -mediated differentiation in human promyelogenous leukemic cell line HL60. Biochem Biophys Res Commun: 2012; 417 594 600
19. Jing Y. The PML-RARalpha fusion protein and targeted therapy for acute promyelocytic leukemia. Leuk Lymphoma: 2004; 45 639 648 (Pubitemid 38256023)
20. Zhao Q., Tao J., Zhu Q., Jia P. M., Dou A. X., Li X., Cheng F., Waxman S., Chen G. Q., Chen S. J., Lanotte M., Chen Z., Tong J. H. Rapid induction of cAMP/PKA pathway during retinoic acid-induced acute promyelocytic leukemia cell differentiation. Leukemia: 2004; 18 285 292 (Pubitemid 38240044)
21. Jiao B., Ren Z. H., Liu P., Chen L. J., Shi J. Y., Dong Y., Ablain J., Shi L., Gao L., Hu J. P., Ren R. B., de Thé H., Chen Z., Chen S. J. 8-CPT-cAMP/all-trans retinoic acid targets t(11; 17) acute promyelocytic leukemia through enhanced cell differentiation and PLZF/RAR α degradation. Proc Natl Acad Sci U S A: 2013; 110 3495 3500
22. Asai M., Tsukamoto O., Minamino T., Asanuma H., Fujita M., Asano Y., Takahama H., Sasaki H., Higo S., Asakura M., Takashima S., Hori M., Kitakaze M. PKA rapidly enhances proteasome assembly and activity in in vivo canine hearts. J Mol Cell Cardiol: 2009; 46 452 462
23. Fang Y., Zhou X., Lin M., Jing H., Zhong L., Ying M., Luo P., Yang B., He Q. The ubiquitin-proteasome pathway plays essential roles in ATRA-induced leukemia cells G0/G1 phase arrest and transition into granulocytic differentiation. Cancer Biol Ther: 2010; 10 1157 1167
24. Gausdal G., Wergeland A., Skavland J., Nguyen E., Pendino F., Rouhee N., McCormack E., Herfindal L., Kleppe R., Havemann U., Schwede F., Bruserud O., Gjertsen B. T., Lanotte M., Ségal-Bendirdjian E., Doskeland S. O. Cyclic AMP can promote APL progression and protect myeloid leukemia cells against anthracycline-induced apoptosis. Cell Death Dis: 2013; 4 e516
25. Yamada O., Ozaki K., Nakatake M., Kakiuchi Y., Akiyama M., Mitsuishi T., Kawauchi K., Matsuoka R. Akt and PKC are involved not only in upregulation of telomerase activity but also in cell differentiation-related function via mTORC2 in leukemia cells. Histochem Cell Biol: 2010; 134 555 563
26. Pendino F., Hillion J., Dudognon C., Delaunay J., Mourah S., Podgorniak M. P., Lafon I., Chomienne C., Lanotte M., Dombret H., Rousselot P., Ségal-Bendirdjian E. Telomerase targeting by retinoids in cells from patients with myeloid leukemias of various subtypes, not only APL. Leukemia: 2006; 20 599 603
27. Akiyama M., Yamada O., Yanagisawa T., Fujisawa K., Eto Y., Yamada H. Analysis of telomerase activity and RNA expression in a patient with acute promyelocytic leukemia treated with all-trans retinoic acid. Pediatr Blood Cancer: 2006; 46 506 511 (Pubitemid 43334660)
28. Pendino F., Sahraoui T., Lanotte M., Ségal-Bendirdjian E. A novel mechanism of retinoic acid resistance in acute promyelocytic leukemia cells through a defective pathway in telomerase regulation. Leukemia: 2002; 16 826 832 (Pubitemid 34537554)
29. Sun J., Huang H., Zhu Y., Lan J., Li J., Lai X., Yu J. The expression of telomeric proteins and their probable regulation of telomerase during the differentiation of all-trans-retinoic acid-responsive and -resistant acute promyelocytic leukemia cells. Int J Hematol: 2005; 82 215 223 (Pubitemid 41552327)
30. Zhu B., Zhang L. H., Zhao Y. M., Cui J. R., Strada S. J. 8-chloroadenosine induced HL-60 cell growth inhibition, differentiation, and G(0)/G(1) arrest involves attenuated cyclin D1 and telomerase and up-regulated p?21(WAF1/CIP1). J Cell Biochem: 2006; 97 166 177 (Pubitemid 43050188)
31. Wang A. P., Zang T., Zhu L. L. Influences of 8-Br-cAMP on the telomerase activity and P53 expression in the human lung adenocarcinoma cell A549 line. J Zhengzhou Univ (Med Sci): 2002; 37 469 471
32. Vávrová A., Šimůnek T. DNA topoisomerase II β: a player in regulation of gene expression and cell differentiation. Int J Biochem Cell Biol: 2012; 44 834 837
33. McNamara S., Wang H., Hanna N., Miller W. H. jr. Topoisomerase II beta negatively modulates retinoic acid receptor alpha function: a novel mechanism of retinoic acid resistance. Mol Cell Biol: 2008; 28 2066 2077 (Pubitemid 351342636)
34. Yang S. Y., Jia X. Z., Feng L. Y., Li S. Y., An G. S., Ni J. H., Jia H. T. Inhibition of topoisomerase II by 8-chloro-adenosine triphosphate induces DNA double-stranded breaks in 8-chloro-adenosine-exposed human myelocytic leukemia K562 cells. Biochem Pharmacol: 2009; 77 433 443
35. Kroll D. J., Sullivan D. M., Gutierrez-Hartmann A., Hoeffler J. P. Modification of DNA topoisomerase II activity via direct interactions with the cyclic adenosine-3′,5′-monophosphate response element-binding protein and related transcription factors. Mol Endocrinol: 1993; 7 305 318 (Pubitemid 23104520)