Akt and PKC are involved not only in upregulation of telomerase activity but also in cell differentiation-related function via mTORC2 in leukemia cells

Histochemistry and Cell Biology

Volumn 134, Issue 6, 2010, Pages 555-563

  Yamada, Osamu ^a   Ozaki, Kohji ^a   Nakatake, Mayuka ^a   Kakiuchi, Yasutaka ^a   Akiyama, Masaharu ^c   Mitsuishi, Tsuyoshi ^b   Kawauchi, Kiyotaka ^d   Matsuoka, Rumiko ^a  

^a TOKYO WOMEN'S MEDICAL UNIVERSITY   (Japan)

^b NIPPON MEDICAL SCHOOL   (Japan)

^c JIKEI UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^d TOKYO WOMEN'S MEDICAL UNIVERSITY   (Japan)

Author keywords

Akt; Cell function; MTORC2; PKC; Telomerase

Indexed keywords

2 MORPHOLINO 8 PHENYLCHROMONE; BISINDOLYLMALEIMIDE; CD11B ANTIGEN; CD14 ANTIGEN; DIMETHYL SULFOXIDE; ESTERASE; MAMMALIAN TARGET OF RAPAMYCIN; NITROBLUE TETRAZOLIUM; PROTEIN KINASE B; PROTEIN KINASE C; PROTEIN KINASE C ALPHA; PROTEIN KINASE C BETA; RETINOIC ACID; RICTOR ASSOCIATED WITH MTOR; RNA; SMALL INTERFERING RNA; TELOMERASE; UNCLASSIFIED DRUG;

ARTICLE; CELL DIFFERENTIATION; CELL FUNCTION; CELL STRAIN HL 60; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INDUCTION; ENZYME REGULATION; GENE SILENCING; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOPHENOTYPING; LEUKEMIA CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; REGULATORY MECHANISM; UPREGULATION;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; CARRIER PROTEINS; CELL DIFFERENTIATION; CHROMONES; HL-60 CELLS; HUMANS; MORPHOLINES; PHOSPHORYLATION; PROTEIN KINASE C; PROTO-ONCOGENE PROTEINS C-AKT; RNA, SMALL INTERFERING; TELOMERASE; TRANSCRIPTION FACTORS; UP-REGULATION;

RAPTORES;

EID: 78651369022     PISSN: 09486143     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00418-010-0764-0     Document Type: Article

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