Hawthorn (Crataegus oxyacantha L.) bark extract regulates antioxidant response element (ARE)-mediated enzyme expression via Nrf2 pathway activation in normal hepatocyte cell line

Phytotherapy Research

Volumn 28, Issue 4, 2014, Pages 593-602

  Krajka Kuźniak, Violetta ^a   Paluszczak, Jarosław ^a   Oszmiański, Jan ^b   Baer Dubowska, Wanda ^a  

^a POZNAN UNIVERSITY OF MEDICAL SCIENCES   (Poland)

^b WROC AW UNIVERSITY OF ENVIRONMENTAL AND LIFE SCIENCES   (Poland)

Author keywords

Hawthorn bark extract; hepatocytes; Nrf2; phase II enzymes

Indexed keywords

5 AZA 2' DEOXYCYTIDINE; B TYPE PA DIMER; B TYPE PA TETRAMER; B TYPE PA TRIMER; CRATAEGUS EXTRACT; EPICATECHIN; GLUTATHIONE TRANSFERASE; HEME OXYGENASE 1; HYPERIN; ISOORIENTIN; ISOQUERCITRIN; ISOVITEXIN; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE; ORIENTIN; PHENOL DERIVATIVE; PLANT MEDICINAL PRODUCT; PROCYANIDIN B2; PROCYANIDIN C1; PROCYANIDIN DERIVATIVE; PROTEIN P53; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE (PHOSPHATE) DEHYDROGENASE (QUINONE); STRESS ACTIVATED PROTEIN KINASE; TRANSCRIPTION FACTOR NRF2; UNCLASSIFIED DRUG; VITEXIN; VITEXIN 2'' RHAMNOSIDE;

ANTIOXIDANT ACTIVITY; ANTIOXIDANT RESPONSIVE ELEMENT; ARTICLE; BARK; CELL LINE; CELL NUCLEUS; CELL STRAIN HEPG2; CHEMOPROPHYLAXIS; CONTROLLED STUDY; CRATAEGUS LAEVIGATA; CYTOSOL; DRUG EFFECT; ENZYME PHOSPHORYLATION; GENE INDUCTION; HUMAN; HUMAN CELL; LIVER CELL; LIVER PROTECTION; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; PROTEIN TRANSPORT;

CRATAEGUS; CRATAEGUS MONOGYNA;

HAWTHORN BARK EXTRACT; HEPATOCYTES; NRF2; PHASE II ENZYMES;

ANTIOXIDANT RESPONSE ELEMENTS; ANTIOXIDANTS; CELL LINE; CRATAEGUS; DNA METHYLATION; GLUTATHIONE TRANSFERASE; HEME OXYGENASE-1; HEP G2 CELLS; HEPATOCYTES; HUMANS; NAD(P)H DEHYDROGENASE (QUINONE); NF-E2-RELATED FACTOR 2; NITRIC OXIDE SYNTHASE TYPE II; PHOSPHORYLATION; PLANT BARK; PLANT EXTRACTS; PROANTHOCYANIDINS; SIGNAL TRANSDUCTION; TUMOR SUPPRESSOR PROTEIN P53;

EID: 84898017895     PISSN: 0951418X     EISSN: 10991573     Source Type: Journal    
DOI: 10.1002/ptr.5035     Document Type: Article

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