Targeting SUR1/Abcc8-type neuroendocrine KATP channels in pancreatic islet cells

PLoS ONE

Volumn 9, Issue 3, 2014, Pages

  Nakamura, Yumiko ^a   Bryan, Joseph ^a  

^a PACIFIC NORTHWEST RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATE SENSITIVE POTASSIUM CHANNEL; ARGININE; CALCIUM; CRE RECOMBINASE; DIAZOXIDE; GLUCOSE; SULFONYLUREA RECEPTOR 1; VOLTAGE GATED CALCIUM CHANNEL; YELLOW FLUORESCENT PROTEIN; ABCC8 PROTEIN, MOUSE; INTEGRASE; SULFONYLUREA RECEPTOR;

ANIMAL CELL; ARTICLE; CHANNEL GATING; CONTROLLED STUDY; FEMALE; MALE; MEMBRANE DEPOLARIZATION; MOUSE; NONHUMAN; PANCREAS ISLET ALPHA CELL; PANCREAS ISLET BETA CELL; PANCREAS ISLET CELL; ANIMAL; CYTOLOGY; GENE TARGETING; GENETICS; METABOLISM; MOLECULAR IMAGING; PANCREAS ISLET; PHENOTYPE; PROCEDURES;

ANIMALS; CALCIUM; FEMALE; GENE TARGETING; INTEGRASES; ISLETS OF LANGERHANS; KATP CHANNELS; MALE; MICE; MOLECULAR IMAGING; PHENOTYPE; SULFONYLUREA RECEPTORS;

EID: 84897980983     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0091525     Document Type: Article

References (42)

1. Unger RH, Orci L (2010) Paracrinology of islets and the paracrinopathy of diabetes. Proc Natl Acad Sci U S A 107: 16009-16012.
2. Unger RH, Cherrington AD (2012) Glucagonocentric restructuring of diabetes: a pathophysiologic and therapeutic makeover. The Journal of clinical investigation 122: 4-12.
3. Farhy LS, McCall AL (2010) Models of glucagon secretion, their application to the analysis of the defects in glucagon counterregulation and potential extension to approximate glucagon action. Journal of diabetes science and technology 4: 1345-1356.
4. Stagner JI, Samols E (1992) The vascular order of islet cellular perfusion in the human pancreas. Diabetes 41: 93-97.
5. ATP channel-dependent pathway within alpha cells regulates glucagon release from both rodent and human islets of Langerhans. PLoS biology 5: e143.
6. ATP-channels and glucose-regulated glucagon secretion. Trends Endocrinol Metab 19: 277-284.
7. Gosmanov NR, Szoke E, Israelian Z, Smith T, Cryer PE, et al. (2005) Role of the decrement in intraislet insulin for the glucagon response to hypoglycemia in humans. Diabetes Care 28: 1124-1131. (Pubitemid 40616623)
8. Raju B, Cryer PE (2005) Loss of the decrement in intraislet insulin plausibly explains loss of the glucagon response to hypoglycemia in insulin-deficient diabetes: documentation of the intraislet insulin hypothesis in humans. Diabetes 54: 757-764. (Pubitemid 40322079)
9. + channel mediates the zinc switch-off signal for glucagon response during glucose deprivation. Diabetes 59: 128-134.
10. Robertson RP, Zhou H, Slucca M (2011) A role for zinc in pancreatic islet beta-cell cross-talk with the alpha-cell during hypoglycaemia. Diabetes, obesity & metabolism 13 Suppl 1: 106-111.
11. Farhy LS, Du Z, Zeng Q, Veldhuis PP, Johnson ML, et al. (2008) Amplification of pulsatile glucagon counterregulation by switch-off of alpha-cell-suppressing signals in streptozotocin-treated rats. Am J Physiol Endocrinol Metab 295: E575-585.
12. de Heer J, Rasmussen C, Coy DH, Holst JJ (2008) Glucagon-like peptide-1, but not glucose-dependent insulinotropic peptide, inhibits glucagon secretion via somatostatin (receptor subtype 2) in the perfused rat pancreas. Diabetologia 51: 2263-2270.
13. Hauge-Evans AC, King AJ, Carmignac D, Richardson CC, Robinson IC, et al. (2009) Somatostatin secreted by islet delta-cells fulfills multiple roles as a paracrine regulator of islet function. Diabetes 58: 403-411.
14. ATP Channels From Both alpha-Cells and delta-Cells. Diabetes 62: 1612-1622.
15. Karimian N, Qin T, Liang T, Osundiji M, Huang Y, et al. (2013) Somatostatin Receptor Type 2 Antagonism Improves Glucagon Counter-regulation In BioBreeding Diabetic Rats. Diabetes.
16. ATP channel-independent regulation of insulin secretion. J Biol Chem 275: 9270-9277.
17. Mohamed Z, Arya VB, Hussain K (2012) Hyperinsulinaemic hypoglycaemia:- genetic mechanisms, diagnosis and management. Journal of clinical research in pediatric endocrinology 4: 169-181.
18. -/- mice by lowering cAMP in pancreatic beta-cells and inhibiting insulin secretion. The Journal of biological chemistry 283: 25786-25793.
19. Shiota C, Larsson O, Shelton KD, Shiota M, Efanov AM, et al. (2002) Sulfonylurea receptor type 1 knock-out mice have intact feeding-stimulated insulin secretion despite marked impairment in their response to glucose. The Journal of biological chemistry 277: 37176-37183.
20. Shiota C, Rocheleau JV, Shiota M, Piston DW, Magnuson MA (2005) Impaired glucagon secretory responses in mice lacking the type 1 sulfonylurea receptor. American journal of physiology Endocrinology and metabolism 289: E570-577. (Pubitemid 41356077)
21. Nenquin M, Szollosi A, Aguilar-Bryan L, Bryan J, Henquin JC (2004) Both triggering and amplifying pathways contribute to fuel-induced insulin secretion in the absence of sulfonylurea receptor-1 in pancreatic beta-cells. The Journal of biological chemistry 279: 32316-32324. (Pubitemid 39014683)
22. Soriano P (1999) Generalized lacZ expression with the ROSA26 Cre reporter strain. Nat Genet 21: 70-71.
23. Srinivas S, Watanabe T, Lin CS, William CM, Tanabe Y, et al. (2001) Cre reporter strains produced by targeted insertion of EYFP and ECFP into the ROSA26 locus. BMC Dev Biol 1: 4.
24. Herrera PL (2000) Adult insulin- and glucagon-producing cells differentiate from two independent cell lineages. Development 127: 2317-2322.
25. 2+ indicators with greatly improved fluorescence properties. The Journal of biological chemistry 260: 3440-3450.
26. 2+ signaling. Endocrinology 137: 693-697.
27. 2+ oscillations in glucagon-producing alpha 2-cells by insulin/glucose and amino acids. Biochimica et biophysica acta 1310: 212-216.
28. ATP: an inward rectifier subunit plus the sulfonylurea receptor. Science 270: 1166-1170.
29. Larsson H, Ahren B (1998) Glucose-dependent arginine stimulation test for characterization of islet function: studies on reproducibility and priming effect of arginine. Diabetologia 41: 772-777. (Pubitemid 28313709)
30. Ward WK, Bolgiano DC, McKnight B, Halter JB, Porte D Jr (1984) Diminished B cell secretory capacity in patients with noninsulin-dependent diabetes mellitus. J Clin Invest 74: 1318-1328. (Pubitemid 15206828)
31. 2+ signal. The Journal of biological chemistry 282: 14768-14776.
32. + channels. The Journal of biological chemistry 282: 1747-1756.
33. c by different mechanisms in isolated mouse alpha-cells. Diabetes 58: 412-421.
34. Kawamori D, Kurpad AJ, Hu J, Liew CW, Shih JL, et al. (2009) Insulin signaling in alpha cells modulates glucagon secretion in vivo. Cell Metab 9: 350-361.
35. Nyman LR, Ford E, Powers AC, Piston DW (2010) Glucose-dependent blood flow dynamics in murine pancreatic islets in vivo. Am J Physiol Endocrinol Metab 298: E807-814.
36. Quoix N, Cheng-Xue R, Guiot Y, Herrera PL, Henquin JC, et al. (2007) The GluCre-ROSA26EYFP mouse: a new model for easy identification of living pancreatic alpha-cells. FEBS Lett 581: 4235-4240. (Pubitemid 47301858)
37. Le Marchand SJ, Piston DW (2010) Glucose suppression of glucagon secretion: metabolic and calcium responses from alpha-cells in intact mouse pancreatic islets. J Biol Chem 285: 14389-14398.
38. Allister EM, Robson-Doucette CA, Prentice KJ, Hardy AB, Sultan S, et al. (2013) UCP2 regulates the glucagon response to fasting and starvation. Diabetes 62: 1623-1633.
39. Araki K, Imaizumi T, Okuyama K, Oike Y, Yamamura K (1997) Efficiency of recombination by Cre transient expression in embryonic stem cells: comparison of various promoters. J Biochem 122: 977-982. (Pubitemid 27510937)
40. Inada A, Nienaber C, Katsuta H, Fujitani Y, Levine J, et al. (2008) Carbonic anhydrase II-positive pancreatic cells are progenitors for both endocrine and exocrine pancreas after birth. Proc Natl Acad Sci U S A 105: 19915-19919.
41. Akopian A, Marshall Stark W (2005) Site-specific DNA recombinases as instruments for genomic surgery. Advances in genetics 55: 1-23. (Pubitemid 43583921)
42. Branda CS, Dymecki SM (2004) Talking about a revolution: The impact of site-specific recombinases on genetic analyses in mice. Developmental cell 6: 7-28. (Pubitemid 38089202)