메뉴 건너뛰기




Volumn 9, Issue 1, 2014, Pages

Changes in oxidative damage, inflammation and [NAD(H)] with age in cerebrospinal fluid

Author keywords

[No Author keywords available]

Indexed keywords

INTERLEUKIN 6; ISOPROSTANE DERIVATIVE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE;

EID: 84897975607     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0085335     Document Type: Article
Times cited : (52)

References (71)
  • 1
    • 77049308856 scopus 로고
    • Aging: A theory based on free radical and radiation chemistry
    • Harman D (1956) Aging: a theory based on free radical and radiation chemistry. J Gerontol 2: 298-300.
    • (1956) J Gerontol , vol.2 , pp. 298-300
    • Harman, D.1
  • 4
    • 80053629048 scopus 로고    scopus 로고
    • Molecular and structural antioxidant defenses against oxidative stress in animals
    • Pamplona R, Costantini D (2011) Molecular and structural antioxidant defenses against oxidative stress in animals. Am J Physiol Regul Integr Comp Physiol 301: R843-R863.
    • (2011) Am J Physiol Regul Integr Comp Physiol , vol.301
    • Pamplona, R.1    Costantini, D.2
  • 5
    • 9244231109 scopus 로고    scopus 로고
    • High-field magnetic resonance imaging of brain iron: Birth of a biomarker?
    • Schenck JF, Zimmerman EA (2004) High-field magnetic resonance imaging of brain iron: birth of a biomarker? NMR Biomed 17: 443-445.
    • (2004) NMR Biomed , vol.17 , pp. 443-445
    • Schenck, J.F.1    Zimmerman, E.A.2
  • 6
    • 0022302720 scopus 로고
    • Lipids of nervous tissue: Composition and metabolism
    • Sastry PS (1985) Lipids of nervous tissue: composition and metabolism. Prog Lipid Res 24: 169-176.
    • (1985) Prog Lipid Res , vol.24 , pp. 169-176
    • Sastry, P.S.1
  • 7
    • 33745013111 scopus 로고    scopus 로고
    • Oxidative stress and Neurodegeneration: Where are we now?
    • Halliwell B (2006) Oxidative stress and Neurodegeneration: where are we now? J Neurochem 97: 1634-1658.
    • (2006) J Neurochem , vol.97 , pp. 1634-1658
    • Halliwell, B.1
  • 8
    • 58549098084 scopus 로고    scopus 로고
    • Blood-brain barrier: Ageing and microvascular disease -systematic review and meta-analysis
    • Farrall AJ, Wardlaw JM (2009) Blood-brain barrier: Ageing and microvascular disease -systematic review and meta-analysis. Neurobiol Aging 30: 337-352.
    • (2009) Neurobiol Aging , vol.30 , pp. 337-352
    • Farrall, A.J.1    Wardlaw, J.M.2
  • 10
    • 84878884842 scopus 로고    scopus 로고
    • Oxidative stress induces apolipoprotein D overexpression in hippocampus during aging and Alzheimer's disease
    • Martínez E, Navarro A, Ordóñez C, Del Valle E, Tolivia J (2013) Oxidative stress induces apolipoprotein D overexpression in hippocampus during aging and Alzheimer's disease. J Alzheimer's Dis 36: 129-144.
    • (2013) J Alzheimer's Dis , vol.36 , pp. 129-144
    • Martínez, E.1    Navarro, A.2    Ordóñez, C.3    Del Valle, E.4    Tolivia, J.5
  • 11
    • 84875980060 scopus 로고    scopus 로고
    • Age-dependent guanine oxidation in DNA of different brain regions of Wistar rats and prematurely aging OXYS rats
    • Sattarova EA, Sinitsyna OI, Vasyunina EA, Duzhak AB, Kolosova NG, et al. (2013) Age-dependent guanine oxidation in DNA of different brain regions of Wistar rats and prematurely aging OXYS rats. Biochim Biophys Acta 1830: 3542-3552.
    • (2013) Biochim Biophys Acta , vol.1830 , pp. 3542-3552
    • Sattarova, E.A.1    Sinitsyna, O.I.2    Vasyunina, E.A.3    Duzhak, A.B.4    Kolosova, N.G.5
  • 12
    • 0035134095 scopus 로고    scopus 로고
    • Relation of oxidative protein damage and nitrotyrosine levels in the aging rat brain
    • DOI 10.1016/S0531-5565(00)00197-2, PII S0531556500001972
    • Cakatay U, Telci A, Kayali R, Tekeli F, Akcay T, et al. (2001) Relation of oxidative protein damage and nitrotyrosine levels in the aging rat brain. Exp Gerontol 36: 221-229. (Pubitemid 32162478)
    • (2001) Experimental Gerontology , vol.36 , Issue.2 , pp. 221-229
    • Cakatay, U.1    Telci, A.2    Kayal, R.3    Tekeli, F.4    Akcay, T.5    Sivas, A.6
  • 17
    • 60849093466 scopus 로고    scopus 로고
    • Current hypotheses for the underlying biology of amyotrophic lateral sclerosis
    • Rothstein JD (2009) Current hypotheses for the underlying biology of amyotrophic lateral sclerosis. Ann Neurol 65 Suppl 1: 3-9.
    • (2009) Ann Neurol , vol.65 , Issue.SUPPL. 1 , pp. 3-9
    • Rothstein, J.D.1
  • 18
    • 0028309624 scopus 로고
    • Effects of ageing on microglia in the normal rat brain: Immunohistochemical observations
    • Ogura K, Ogawa M, Yoshida M (1994) Effects of ageing on microglia in the normal rat brain: immunohistochemical observations. Neuroreport 5: 1224-1226. (Pubitemid 24199801)
    • (1994) NeuroReport , vol.5 , Issue.10 , pp. 1224-1226
    • Ogura, K.-I.1    Ogawa, M.2    Yoshida, M.3
  • 19
  • 20
    • 1042291300 scopus 로고    scopus 로고
    • Dystrophic Microglia in the Aging Human Brain
    • DOI 10.1002/glia.10319
    • Streit WJ, Sammons NW, Kuhns AJ, Sparks DL (2004) Dystrophic microglia in the aging human brain. Glia 45: 208-212. (Pubitemid 38196997)
    • (2004) GLIA , vol.45 , Issue.2 , pp. 208-212
    • Streit, W.J.1    Sammons, N.W.2    Kuhns, A.J.3    Sparks, D.L.4
  • 21
    • 81355132325 scopus 로고    scopus 로고
    • Ex vivo cultures of microglia from young and aged rodent brain reveal age-related changes in microglial function
    • Njie EG, Boelen E, Stassen FR, Steinbusch HWM, Borchelt DR, et al. (2012) Ex vivo cultures of microglia from young and aged rodent brain reveal age-related changes in microglial function. Neurobiol Aging 33: 195.e1-195.e12.
    • (2012) Neurobiol Aging , vol.33
    • Njie, E.G.1    Boelen, E.2    Stassen, F.R.3    Steinbusch, H.W.M.4    Borchelt, D.R.5
  • 22
    • 84875670965 scopus 로고    scopus 로고
    • Elevated levels of interleukin 6 and c-reactive protein associated with cognitive impairment in heart failure
    • Athilingam P, Moynihan J, Chen L, D'Aoust R, Groer M, et al. (2013) Elevated levels of interleukin 6 and c-reactive protein associated with cognitive impairment in heart failure. Congest Heart Fail 19: 92-98.
    • (2013) Congest Heart Fail , vol.19 , pp. 92-98
    • Athilingam, P.1    Moynihan, J.2    Chen, L.3    D'Aoust, R.4    Groer, M.5
  • 23
    • 1642420308 scopus 로고    scopus 로고
    • Interleukin-6 induces Alzheimer-type phosphorylation of tau protein by deregulating the cdk5/p35 pathway
    • DOI 10.1016/j.yexcr.2004.01.002, PII S0014482704000187
    • Quintanilla R, Orellana D, Gonzalez-Billault C, Maccioni RB (2004) Interleukin-6 induces Alzheimer's phosphorylation of tau protein by deregulating the cdk5/p35 pathway. Exp Cell Res 295: 245-257. (Pubitemid 38407361)
    • (2004) Experimental Cell Research , vol.295 , Issue.1 , pp. 245-257
    • Quintanilla, R.A.1    Orellana, D.I.2    Gonzalez-Billault, C.3    Maccioni, R.B.4
  • 24
    • 79955591489 scopus 로고    scopus 로고
    • Age related changes in NAD+ metabolism oxidative stress and sirt1 activity in Wister rats
    • Braidy N, Guillemin GJ, Mansour H, Chan-Ling T, Poljak A, et al. (2011) Age related changes in NAD+ metabolism oxidative stress and sirt1 activity in Wister rats. PLoS ONE 6: e19194.
    • (2011) PLoS ONE , vol.6
    • Braidy, N.1    Guillemin, G.J.2    Mansour, H.3    Chan-Ling, T.4    Poljak, A.5
  • 25
    • 0033198919 scopus 로고    scopus 로고
    • Poly(ADP-ribosyl)ation reactions in the regulation of nuclear functions
    • DOI 10.1042/0264-6021:3420249
    • D'Amours D, Desnoyers S, D'Silva I, Poirier GG (1999) Poly(ADP-ribosyl)ation reactions in the regulation of nuclear functions. Biochem J 342: 249-268. (Pubitemid 29425344)
    • (1999) Biochemical Journal , vol.342 , Issue.2 , pp. 249-268
    • D'Amours, D.1    Desnoyers, S.2    D'Silva, I.3    Poirier, G.G.4
  • 26
    • 84873929641 scopus 로고    scopus 로고
    • The 2.5 Å crystal structure of the SIRT1 catalytic domain bound to nicotinamide adenine dinucleotide (NAD+) and an indole (EX527 analogue) reveals a novel mechanism of histone deacetylase inhibition
    • Zhao X, Allison D, Condon B, Zhang F, Gheyi T, et al. (2013) The 2.5 Å crystal structure of the SIRT1 catalytic domain bound to nicotinamide adenine dinucleotide (NAD+) and an indole (EX527 analogue) reveals a novel mechanism of histone deacetylase inhibition. J Med Chem 56: 963-969.
    • (2013) J Med Chem , vol.56 , pp. 963-969
    • Zhao, X.1    Allison, D.2    Condon, B.3    Zhang, F.4    Gheyi, T.5
  • 27
    • 78651177271 scopus 로고
    • Energy-linked reduction of the mitochondrial nicotinamide-adenine
    • Szarkowska L, Erecinska M (1965) Energy-linked reduction of the mitochondrial nicotinamide-adenine. Acta Biochim Pol 12: 179-186.
    • (1965) Acta Biochim Pol , vol.12 , pp. 179-186
    • Szarkowska, L.1    Erecinska, M.2
  • 29
    • 77649133016 scopus 로고    scopus 로고
    • + depletion is necessary and sufficient for Poly(ADP-Ribose) Polymerase-1-mediated neuronal death
    • + depletion is necessary and sufficient for Poly(ADP-Ribose) Polymerase-1-mediated neuronal death. J Neuro 30: 2967-2978.
    • (2010) J Neuro , vol.30 , pp. 2967-2978
    • Alano, C.C.1    Garnier, P.2    Ying, W.3    Higashi, Y.4    Kauppinen, T.M.5
  • 30
    • 0021997074 scopus 로고
    • Poly(ADP-ribose) in the cellular response to DNA damage
    • Berger NA (1985) Poly(ADP-ribose) in the cellular response to DNA damage. Radiat Res 101: 4-15.
    • (1985) Radiat Res , vol.101 , pp. 4-15
    • Berger, N.A.1
  • 32
    • 0024317904 scopus 로고
    • Prevalence of Alzheimer's disease in a community population of older persons. Higher than previously reported
    • Evans DA, Funkenstein HH, Albert MS, Scherr PA, Cook NR, et al. (1989) Prevalence of Alzheimer's disease in a community population of older persons. Higher than previously reported JAMA 262: 2551-2556.
    • (1989) JAMA , vol.262 , pp. 2551-2556
    • Evans, D.A.1    Funkenstein, H.H.2    Albert, M.S.3    Scherr, P.A.4    Cook, N.R.5
  • 33
    • 0028338865 scopus 로고
    • Prevalence of movement disorders in elderly community residents
    • Moghal S, Rajput AH, D'Arcy C, Rajput R (1994) Prevalence of movement disorders in elderly community residents. Neuroepidemiology 13: 175-178. (Pubitemid 24197317)
    • (1994) Neuroepidemiology , vol.13 , Issue.4 , pp. 175-178
    • Moghal, S.1    Rajput, A.H.2    D'Arcy, C.3    Rajput, R.4
  • 34
    • 0031881598 scopus 로고    scopus 로고
    • The neuropathology of alcohol-specific brain damage, or does alcohol damage the brain?
    • Harper C (1998) The neuropathology of alcohol-specific brain damage, or does alcohol damage the brain? J. Neuropathol Exp Neurol 57: 101-110.
    • (1998) J. Neuropathol Exp Neurol , vol.57 , pp. 101-110
    • Harper, C.1
  • 35
  • 36
    • 0015888084 scopus 로고
    • An improved cycling assay for nicotinamide adenine dinucleotide
    • Bernofsky C, Swan M (1973) An improved cycling assay for nicotinamide adenine dinucleotide. Anal Biochem 53: 452-458.
    • (1973) Anal Biochem , vol.53 , pp. 452-458
    • Bernofsky, C.1    Swan, M.2
  • 37
    • 0031930117 scopus 로고    scopus 로고
    • Murine glial cells regenerate NAD, after peroxide-induced depletion, using either nicotinic acid, nicotinamide, or quinolinic acid as substrates
    • Grant RS, Kapoor V (1998) Murine glial cells regenerate NAD, after peroxide induced depletion, using either nicotinic acid, nicotinamide, or quinolinic acid as substrates. J Neurochem 70: 1759-1763. (Pubitemid 28136993)
    • (1998) Journal of Neurochemistry , vol.70 , Issue.4 , pp. 1759-1763
    • Grant, R.S.1    Kapoor, V.2
  • 38
    • 0033105976 scopus 로고    scopus 로고
    • 2- isoprostanes using gas chromatography-mass spectrometry
    • DOI 10.1006/abio.1998.3037
    • Mori TA, Croft KD, Puddey IB, Beilin LJ (1999) An improved method for the measurement of urinary and plasma F2-isoprostanes using gas chromatography-mass spectrometry. Anal Biochem 268: 117-125. (Pubitemid 29115518)
    • (1999) Analytical Biochemistry , vol.268 , Issue.1 , pp. 117-125
    • Mori, T.A.1    Croft, K.D.2    Puddey, I.B.3    Beilin, L.J.4
  • 39
    • 67749114631 scopus 로고    scopus 로고
    • Midlife serum cholesterol and increased risk of alzheimer's and vascular dementia three decades later
    • Solomon A, Kivipelto M, Wolozin B, Zhou J, Whitmer RA (2009) Midlife serum cholesterol and increased risk of alzheimer's and vascular dementia three decades later. Dement Geriatr Cogn Disord 28: 75-80.
    • (2009) Dement Geriatr Cogn Disord , vol.28 , pp. 75-80
    • Solomon, A.1    Kivipelto, M.2    Wolozin, B.3    Zhou, J.4    Whitmer, R.A.5
  • 40
    • 84855528737 scopus 로고    scopus 로고
    • Total and specific polyphenol intakes in midlife are associated with cognitive function measured 13 years later
    • Kesse-Guyot E, Fezeu L, Andreeva VA, Touvier M, Scalbert A, et al. (2012) Total and specific polyphenol intakes in midlife are associated with cognitive function measured 13 years later. J Nutr 142: 76-83.
    • (2012) J Nutr , vol.142 , pp. 76-83
    • Kesse-Guyot, E.1    Fezeu, L.2    Andreeva, V.A.3    Touvier, M.4    Scalbert, A.5
  • 42
    • 22144451172 scopus 로고    scopus 로고
    • The age-dependent relation of blood pressure to cognitive function and dementia
    • DOI 10.1016/S1474-4422(05)70141-1, PII S1474442205701411
    • Qiu C, Winblad B, Fratiglioni L (2005) The age-dependent relation of blood pressure to cognitive function and dementia. Lancet 4: 487-499. (Pubitemid 40982459)
    • (2005) Lancet Neurology , vol.4 , Issue.8 , pp. 487-499
    • Qiu, C.1    Winblad, B.2    Fratiglioni, L.3
  • 44
    • 0031909973 scopus 로고    scopus 로고
    • Enlarged and phagocytic, but not primed, interleukin-1́- immunoreactive microglia increase with age in normal human brain
    • DOI 10.1007/s004010050792
    • Sheng JG, Mrak RE, Griffin WST (1998) Enlarged and phagocytic, but not primed, interleukin-1á-immunoreactive microglia increase with age in normal human brain. Acta Neuropathol 95: 229-234. (Pubitemid 28120667)
    • (1998) Acta Neuropathologica , vol.95 , Issue.3 , pp. 229-234
    • Sheng, J.G.1    Mrak, R.E.2    Griffin, W.S.T.3
  • 45
    • 25444463296 scopus 로고    scopus 로고
    • +
    • +. Febs J 272: 4576-4589.
    • (2005) Febs J , vol.272 , pp. 4576-4589
    • Burkle, A.1
  • 51
    • 3943092621 scopus 로고    scopus 로고
    • Pathways towards and away from Alzheimer's disease
    • Mattson MP (2004) Pathways towards and away from Alzheimer's disease. Nature 430: 631-639.
    • (2004) Nature , vol.430 , pp. 631-639
    • Mattson, M.P.1
  • 52
    • 65249173918 scopus 로고    scopus 로고
    • Nicotinamide prevents NAD1 depletion and protects neurons against excitotoxicity and cerebral ischemia: NAD1 consumption by SIRT1 may endanger energetically compromised neurons
    • Liu D, Gharavi R, Pitta M, Gleichmann M, Mattson MP (2009) Nicotinamide prevents NAD1 depletion and protects neurons against excitotoxicity and cerebral ischemia: NAD1 consumption by SIRT1 may endanger energetically compromised neurons. Neuromol Med 11: 28-42.
    • (2009) Neuromol Med , vol.11 , pp. 28-42
    • Liu, D.1    Gharavi, R.2    Pitta, M.3    Gleichmann, M.4    Mattson, M.P.5
  • 53
    • 0036246027 scopus 로고    scopus 로고
    • Bioavailability of reduced nicotinamide-adenin-dinucleotide (NADH) in the central nervous system of the anaesthetized rat measured by laser-induced fluorescence spectroscopy
    • DOI 10.1034/j.1600-0773.2002.900409.x
    • Rex A, Hentschke M-P, Fink H (2002) Bioavailability of reduced nicotinamide-adenin-dinucleotide (NADH) in the central nervous system of the anaesthetized rat measured by laser-induced fluorescence spectroscopy. Pharmacol Toxicol 90: 220-225. (Pubitemid 34478345)
    • (2002) Pharmacology and Toxicology , vol.90 , Issue.4 , pp. 220-225
    • Rex, A.1    Hentschke, M.-P.2    Fink, H.3
  • 54
    • 0014428566 scopus 로고
    • Studies on the biosynthesis of nicotinamide-adenine dinucleotide in the brain
    • Deguchi T, Ichiyama A, Nishizuka Y, Hayaish O (1968) Studies on the biosynthesis of nicotinamide-adenine dinucleotide in the brain. Biochem Biophys Acta 158: 382-393.
    • (1968) Biochem Biophys Acta , vol.158 , pp. 382-393
    • Deguchi, T.1    Ichiyama, A.2    Nishizuka, Y.3    Hayaish, O.4
  • 55
    • 84859770335 scopus 로고    scopus 로고
    • Kynurenine pathway metabolism is involved in the maintenance of the intracellular NAD+ concentration in human primary astrocytes
    • Grant R, Nguyen S, Guillemin G (2010) Kynurenine pathway metabolism is involved in the maintenance of the intracellular NAD+ concentration in human primary astrocytes. Int J Tryp Res 3: 151-156.
    • (2010) Int J Tryp Res , vol.3 , pp. 151-156
    • Grant, R.1    Nguyen, S.2    Guillemin, G.3
  • 57
    • 0347356532 scopus 로고    scopus 로고
    • Alcohol Intake and Cerebral Abnormalities on Magnetic Resonance Imaging in A Community-Based Population of Middle-Aged Adults: The Atherosclerosis Risk in Communities (ARIC) Study
    • DOI 10.1161/01.STR.0000105929.88691.8E
    • Ding J, Eigenbrodt ML, Mosley TH Jr, Hutchinson RG, Folsom AR, et al. (2004) Alcohol intake and cerebral abnormalities on magnetic resonance imaging in a community based sample of middle-aged adults: the arteriosclerosis risk in communities (ARIC) study. Stroke 35: 16-21. (Pubitemid 38057582)
    • (2004) Stroke , vol.35 , Issue.1 , pp. 16-21
    • Ding, J.1    Eigenbrodt, M.L.2    Mosley Jr., T.H.3    Hutchinson, R.G.4    Folsom, A.R.5    Harris, T.B.6    Nieto, F.J.7
  • 60
    • 67649749221 scopus 로고    scopus 로고
    • Chronic effects of low to moderate alcohol consumption on structural and functional properties of the brain: Beneficial or not?
    • Verbaten MN (2009) Chronic effects of low to moderate alcohol consumption on structural and functional properties of the brain: beneficial or not? Hum Psychopharmacol Clin Exp 24: 199-205.
    • (2009) Hum Psychopharmacol Clin Exp , vol.24 , pp. 199-205
    • Verbaten, M.N.1
  • 61
    • 0028902051 scopus 로고
    • Mutations in the cell adhesion molecule L1 cause mental retardation
    • Wong EV, Kenwrick S, Willems P, Lemmon V (1995) Mutations in the cell adhesion molecule L1 cause mental retardation. Trends Neurosci 18: 168-172.
    • (1995) Trends Neurosci , vol.18 , pp. 168-172
    • Wong, E.V.1    Kenwrick, S.2    Willems, P.3    Lemmon, V.4
  • 63
    • 0033844602 scopus 로고    scopus 로고
    • Alcohol exposure alters the expression pattern of neural cell adhesion molecules during brain development
    • DOI 10.1046/j.1471-4159.2000.0750954.x
    • Minana R, Climent E, Barettino D, Segui JM, Renau-Piqueras J, et al. (2000) Alcohol exposure alters the expression pattern of neural cell adhesion molecules during brain development. J Neurochem 75: 954-964. (Pubitemid 30660483)
    • (2000) Journal of Neurochemistry , vol.75 , Issue.3 , pp. 954-964
    • Minana, R.1    Climent, E.2    Barettino, D.3    Segui, J.M.4    Renau-Piqueras, J.5    Guerri, C.6
  • 64
    • 84855281868 scopus 로고    scopus 로고
    • Mechanisms of alcohol-induced endoplasmic reticulum stress and organ injuries
    • Ji C (2012) Mechanisms of alcohol-induced endoplasmic reticulum stress and organ injuries. Biochem Res Int: art no 216450.
    • (2012) Biochem Res Int , pp. 216450
    • Ji, C.1
  • 65
    • 80051904574 scopus 로고    scopus 로고
    • Pharmacological activation/inhibition of the cannabinoid system affects alcohol withdrawal-induced neuronal hypersensitivity to excitotoxic insults
    • Rubio M, Villain H, Docagne F, Roussel BD, Ramos JA, et al. (2011) Pharmacological activation/inhibition of the cannabinoid system affects alcohol withdrawal-induced neuronal hypersensitivity to excitotoxic insults. PLoS ONE 6: art no e23690.
    • (2011) PLoS ONE , vol.6
    • Rubio, M.1    Villain, H.2    Docagne, F.3    Roussel, B.D.4    Ramos, J.A.5
  • 66
    • 0027220442 scopus 로고
    • Effects of in utero administration of alcohol on glutathione levels in brain and liver
    • Reyes E, Ott S, Robinson B (1993) Effects of in utero administration of alcohol on glutathione levels in brain and liver. Alcohol Clin Exp Res 17: 877-881. (Pubitemid 23249039)
    • (1993) Alcoholism: Clinical and Experimental Research , vol.17 , Issue.4 , pp. 877-881
    • Reyes, E.1    Ott, S.2    Robinson, B.3
  • 68
    • 28844498785 scopus 로고    scopus 로고
    • Alcohol-induced oxidative stress in brain endothelial cells causes blood-brain barrier dysfunction
    • DOI 10.1189/jlb.0605340
    • Haorah J, Knipe B, Leibhart J, Ghorpade A, Persidsky Y (2005) Alcohol-induced oxidative stress in brain endothelial cells causes blood-brain barrier dysfunction. J Leukoc Biol 78: 1223-1232. (Pubitemid 41779228)
    • (2005) Journal of Leukocyte Biology , vol.78 , Issue.6 , pp. 1223-1232
    • Haorah, J.1    Knipe, B.2    Leibhart, J.3    Ghorpade, A.4    Persidsky, Y.5
  • 69
    • 38949188640 scopus 로고    scopus 로고
    • Lipid rafts regulate ethanol-induced activation of TLR4 signaling in murine macrophages
    • DOI 10.1016/j.molimm.2007.10.025, PII S0161589007008176
    • Fernandez-Lizarbe S, Pascual M, Gascon MS, Blanco A, Guerri C (2008) Lipid rafts regulate ethanol-induced activation of TLR4 signaling in murine macrophages. Mol Immunol 45: 2007-2016. (Pubitemid 351226271)
    • (2008) Molecular Immunology , vol.45 , Issue.7 , pp. 2007-2016
    • Fernandez-Lizarbe, S.1    Pascual, M.2    Gascon, M.S.3    Blanco, A.4    Guerri, C.5
  • 70
    • 27744562724 scopus 로고    scopus 로고
    • Involvement of TLR4/type I IL-1 receptor signaling in the induction of inflammatory mediators and cell death induced by ethanol in cultured astrocytes
    • Blanco AM, Valles SL, Pascual M, Guerri C (2005) Involvement of TLR4/type I IL-1 receptor signaling in the induction of inflammatory mediators and cell death induced by ethanol in cultured astrocytes. J Immunol 175: 6893-6899. (Pubitemid 41599911)
    • (2005) Journal of Immunology , vol.175 , Issue.10 , pp. 6893-6899
    • Blanco, A.M.1    Valles, S.L.2    Pascual, M.3    Guerri, C.4
  • 71
    • 0020600287 scopus 로고
    • +) levels in Drosophila
    • McElfresh KC, McDonald JF (1983) The effect of alcohol stress on nicotinamide adenine dinucleotide (NAD+) levels in Drosophila. Biochem Gen 21: 365-374. (Pubitemid 13085444)
    • (1983) Biochemical Genetics , vol.21 , Issue.3-4 , pp. 365-374
    • McElfresh, K.C.1    McDonald, J.F.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.