-
1
-
-
77049308856
-
Aging: A theory based on free radical and radiation chemistry
-
Harman D (1956) Aging: a theory based on free radical and radiation chemistry. J Gerontol 2: 298-300.
-
(1956)
J Gerontol
, vol.2
, pp. 298-300
-
-
Harman, D.1
-
3
-
-
17244363631
-
Decline in skeletal muscle mitochondrial function with aging in humans
-
DOI 10.1073/pnas.0501559102
-
Short K, Bigelow M, Kahl J, Singh R, Coenen S, et al. (2005) Decline in skeletal muscle mitochondrial function with aging in humans. Proc Natl Acad Sci USA 102: 5618-5623. (Pubitemid 40530306)
-
(2005)
Proceedings of the National Academy of Sciences of the United States of America
, vol.102
, Issue.15
, pp. 5618-5623
-
-
Short, K.R.1
Bigelow, M.L.2
Kahl, J.3
Singh, R.4
Coenen-Schimke, J.5
Raghavakaimal, S.6
Nair, K.S.7
-
4
-
-
80053629048
-
Molecular and structural antioxidant defenses against oxidative stress in animals
-
Pamplona R, Costantini D (2011) Molecular and structural antioxidant defenses against oxidative stress in animals. Am J Physiol Regul Integr Comp Physiol 301: R843-R863.
-
(2011)
Am J Physiol Regul Integr Comp Physiol
, vol.301
-
-
Pamplona, R.1
Costantini, D.2
-
5
-
-
9244231109
-
High-field magnetic resonance imaging of brain iron: Birth of a biomarker?
-
Schenck JF, Zimmerman EA (2004) High-field magnetic resonance imaging of brain iron: birth of a biomarker? NMR Biomed 17: 443-445.
-
(2004)
NMR Biomed
, vol.17
, pp. 443-445
-
-
Schenck, J.F.1
Zimmerman, E.A.2
-
6
-
-
0022302720
-
Lipids of nervous tissue: Composition and metabolism
-
Sastry PS (1985) Lipids of nervous tissue: composition and metabolism. Prog Lipid Res 24: 169-176.
-
(1985)
Prog Lipid Res
, vol.24
, pp. 169-176
-
-
Sastry, P.S.1
-
7
-
-
33745013111
-
Oxidative stress and Neurodegeneration: Where are we now?
-
Halliwell B (2006) Oxidative stress and Neurodegeneration: where are we now? J Neurochem 97: 1634-1658.
-
(2006)
J Neurochem
, vol.97
, pp. 1634-1658
-
-
Halliwell, B.1
-
8
-
-
58549098084
-
Blood-brain barrier: Ageing and microvascular disease -systematic review and meta-analysis
-
Farrall AJ, Wardlaw JM (2009) Blood-brain barrier: Ageing and microvascular disease -systematic review and meta-analysis. Neurobiol Aging 30: 337-352.
-
(2009)
Neurobiol Aging
, vol.30
, pp. 337-352
-
-
Farrall, A.J.1
Wardlaw, J.M.2
-
9
-
-
0027527023
-
Oxidative damage to mitochondrial DNA shows marked age-dependent increases in human brain
-
Mecocci P, MacGarvey U, Kaufman AE, Koontz D, Shoffner JM, et al. (1993) Oxidative damage to mitochondrial DNA shows marked age-dependent increases in human brain. Ann Neurol 34: 609-616. (Pubitemid 23289414)
-
(1993)
Annals of Neurology
, vol.34
, Issue.4
, pp. 609-616
-
-
Mecocci, P.1
MacGarvey, U.2
Kaufman, A.E.3
Koontz, D.4
Shoffner, J.M.5
Wallace, D.C.6
Beal, M.F.7
-
10
-
-
84878884842
-
Oxidative stress induces apolipoprotein D overexpression in hippocampus during aging and Alzheimer's disease
-
Martínez E, Navarro A, Ordóñez C, Del Valle E, Tolivia J (2013) Oxidative stress induces apolipoprotein D overexpression in hippocampus during aging and Alzheimer's disease. J Alzheimer's Dis 36: 129-144.
-
(2013)
J Alzheimer's Dis
, vol.36
, pp. 129-144
-
-
Martínez, E.1
Navarro, A.2
Ordóñez, C.3
Del Valle, E.4
Tolivia, J.5
-
11
-
-
84875980060
-
Age-dependent guanine oxidation in DNA of different brain regions of Wistar rats and prematurely aging OXYS rats
-
Sattarova EA, Sinitsyna OI, Vasyunina EA, Duzhak AB, Kolosova NG, et al. (2013) Age-dependent guanine oxidation in DNA of different brain regions of Wistar rats and prematurely aging OXYS rats. Biochim Biophys Acta 1830: 3542-3552.
-
(2013)
Biochim Biophys Acta
, vol.1830
, pp. 3542-3552
-
-
Sattarova, E.A.1
Sinitsyna, O.I.2
Vasyunina, E.A.3
Duzhak, A.B.4
Kolosova, N.G.5
-
12
-
-
0035134095
-
Relation of oxidative protein damage and nitrotyrosine levels in the aging rat brain
-
DOI 10.1016/S0531-5565(00)00197-2, PII S0531556500001972
-
Cakatay U, Telci A, Kayali R, Tekeli F, Akcay T, et al. (2001) Relation of oxidative protein damage and nitrotyrosine levels in the aging rat brain. Exp Gerontol 36: 221-229. (Pubitemid 32162478)
-
(2001)
Experimental Gerontology
, vol.36
, Issue.2
, pp. 221-229
-
-
Cakatay, U.1
Telci, A.2
Kayal, R.3
Tekeli, F.4
Akcay, T.5
Sivas, A.6
-
13
-
-
0037418621
-
Apoptosis induced in neuronal cells by oxidative stress: Role played by caspases and intracellular calcium ions
-
DOI 10.1016/S0378-4274(02)00427-7, PII S0378427402004277
-
Annunziato L, Amoroso S, Pannaccione A, Cataldi M, Pignataro G, et al. (2003) Apoptosis induced in neuronal cells by oxidative stress: role played by caspases and intracellular calcium ions. Toxicol Lett 139: 125-133. (Pubitemid 36298971)
-
(2003)
Toxicology Letters
, vol.139
, Issue.2-3
, pp. 125-133
-
-
Annunziato, L.1
Amoroso, S.2
Pannaccione, A.3
Cataldi, M.4
Pignataro, G.5
D'Alessio, A.6
Sirabella, R.7
Secondo, A.8
Sibaud, L.9
Di, R.G.F.10
-
14
-
-
0034923434
-
Oxidative damage is the earliest event in Alzheimer disease
-
Nunomura A, Perry G, Aliev G, Hirai K, Takeda A, et al. (2001) Oxidative damage is the earliest event in Alzheimer disease. J Neuropathol Exp Neurol 60: 759-767. (Pubitemid 32678256)
-
(2001)
Journal of Neuropathology and Experimental Neurology
, vol.60
, Issue.8
, pp. 759-767
-
-
Nunomura, A.1
Perry, G.2
Aliev, G.3
Hirai, K.4
Takeda, A.5
Balraj, E.K.6
Jones, P.K.7
Ghanbari, H.8
Wataya, T.9
Shimohama, S.10
Chiba, S.11
Atwood, C.S.12
Petersen, R.B.13
Smith, M.A.14
-
15
-
-
1242338183
-
Involvement of oxidative stress-induced abnormalities in ceramide and cholesterol metabolism in brain aging and Alzheimer's disease
-
DOI 10.1073/pnas.0305799101
-
Cutler RG, Kelly J, Storie K, Pedersen WA, Tammara A, et al. (2004) Involvement of oxidative stress induced abnormalities in ceramide and cholesterol metabolism in brain aging and Alzheimer's disease. Proc Natl Acad Sci USA 101: 2070-2075. (Pubitemid 38229016)
-
(2004)
Proceedings of the National Academy of Sciences of the United States of America
, vol.101
, Issue.7
, pp. 2070-2075
-
-
Cutler, R.G.1
Kelly, J.2
Storie, K.3
Pedersen, W.A.4
Tammara, A.5
Hatanpaa, K.6
Troncoso, J.C.7
Mattson, M.P.8
-
16
-
-
0024585155
-
Basal lipid peroxidation in substantia nigra is increased in Parkinson's disease
-
DOI 10.1111/j.1471-4159.1989.tb09133.x
-
Dexter DT, Carter CJ, Wells FR, Javoy-Agid F, Agid Y, et al. (1989) Basal lipid peroxidation in substantia nigra is increased in Parkinson's disease. J Neurochem 52: 381-389. (Pubitemid 19037600)
-
(1989)
Journal of Neurochemistry
, vol.52
, Issue.2
, pp. 381-389
-
-
Dexter, D.T.1
Carter, C.J.2
Wells, F.R.3
Javoy-Agid, F.4
Agid, Y.5
Lees, A.6
Jenner, P.7
Marsden, C.D.8
-
17
-
-
60849093466
-
Current hypotheses for the underlying biology of amyotrophic lateral sclerosis
-
Rothstein JD (2009) Current hypotheses for the underlying biology of amyotrophic lateral sclerosis. Ann Neurol 65 Suppl 1: 3-9.
-
(2009)
Ann Neurol
, vol.65
, Issue.SUPPL. 1
, pp. 3-9
-
-
Rothstein, J.D.1
-
18
-
-
0028309624
-
Effects of ageing on microglia in the normal rat brain: Immunohistochemical observations
-
Ogura K, Ogawa M, Yoshida M (1994) Effects of ageing on microglia in the normal rat brain: immunohistochemical observations. Neuroreport 5: 1224-1226. (Pubitemid 24199801)
-
(1994)
NeuroReport
, vol.5
, Issue.10
, pp. 1224-1226
-
-
Ogura, K.-I.1
Ogawa, M.2
Yoshida, M.3
-
19
-
-
33646006075
-
mRNA up-regulation of MHC II and pivotal pro-inflammatory genes in normal brain aging
-
Frank MG, Barrientos RM, Biedenkapp JC, Rudy JW, Watkins LR, et al. (2005) mRNA up-regulation of MHC II and pivotal pro-inflammatory genes in normal brain aging. Neurobiol Aging 27: 717-722.
-
(2005)
Neurobiol Aging
, vol.27
, pp. 717-722
-
-
Frank, M.G.1
Barrientos, R.M.2
Biedenkapp, J.C.3
Rudy, J.W.4
Watkins, L.R.5
-
20
-
-
1042291300
-
Dystrophic Microglia in the Aging Human Brain
-
DOI 10.1002/glia.10319
-
Streit WJ, Sammons NW, Kuhns AJ, Sparks DL (2004) Dystrophic microglia in the aging human brain. Glia 45: 208-212. (Pubitemid 38196997)
-
(2004)
GLIA
, vol.45
, Issue.2
, pp. 208-212
-
-
Streit, W.J.1
Sammons, N.W.2
Kuhns, A.J.3
Sparks, D.L.4
-
21
-
-
81355132325
-
Ex vivo cultures of microglia from young and aged rodent brain reveal age-related changes in microglial function
-
Njie EG, Boelen E, Stassen FR, Steinbusch HWM, Borchelt DR, et al. (2012) Ex vivo cultures of microglia from young and aged rodent brain reveal age-related changes in microglial function. Neurobiol Aging 33: 195.e1-195.e12.
-
(2012)
Neurobiol Aging
, vol.33
-
-
Njie, E.G.1
Boelen, E.2
Stassen, F.R.3
Steinbusch, H.W.M.4
Borchelt, D.R.5
-
22
-
-
84875670965
-
Elevated levels of interleukin 6 and c-reactive protein associated with cognitive impairment in heart failure
-
Athilingam P, Moynihan J, Chen L, D'Aoust R, Groer M, et al. (2013) Elevated levels of interleukin 6 and c-reactive protein associated with cognitive impairment in heart failure. Congest Heart Fail 19: 92-98.
-
(2013)
Congest Heart Fail
, vol.19
, pp. 92-98
-
-
Athilingam, P.1
Moynihan, J.2
Chen, L.3
D'Aoust, R.4
Groer, M.5
-
23
-
-
1642420308
-
Interleukin-6 induces Alzheimer-type phosphorylation of tau protein by deregulating the cdk5/p35 pathway
-
DOI 10.1016/j.yexcr.2004.01.002, PII S0014482704000187
-
Quintanilla R, Orellana D, Gonzalez-Billault C, Maccioni RB (2004) Interleukin-6 induces Alzheimer's phosphorylation of tau protein by deregulating the cdk5/p35 pathway. Exp Cell Res 295: 245-257. (Pubitemid 38407361)
-
(2004)
Experimental Cell Research
, vol.295
, Issue.1
, pp. 245-257
-
-
Quintanilla, R.A.1
Orellana, D.I.2
Gonzalez-Billault, C.3
Maccioni, R.B.4
-
24
-
-
79955591489
-
Age related changes in NAD+ metabolism oxidative stress and sirt1 activity in Wister rats
-
Braidy N, Guillemin GJ, Mansour H, Chan-Ling T, Poljak A, et al. (2011) Age related changes in NAD+ metabolism oxidative stress and sirt1 activity in Wister rats. PLoS ONE 6: e19194.
-
(2011)
PLoS ONE
, vol.6
-
-
Braidy, N.1
Guillemin, G.J.2
Mansour, H.3
Chan-Ling, T.4
Poljak, A.5
-
25
-
-
0033198919
-
Poly(ADP-ribosyl)ation reactions in the regulation of nuclear functions
-
DOI 10.1042/0264-6021:3420249
-
D'Amours D, Desnoyers S, D'Silva I, Poirier GG (1999) Poly(ADP-ribosyl)ation reactions in the regulation of nuclear functions. Biochem J 342: 249-268. (Pubitemid 29425344)
-
(1999)
Biochemical Journal
, vol.342
, Issue.2
, pp. 249-268
-
-
D'Amours, D.1
Desnoyers, S.2
D'Silva, I.3
Poirier, G.G.4
-
26
-
-
84873929641
-
The 2.5 Å crystal structure of the SIRT1 catalytic domain bound to nicotinamide adenine dinucleotide (NAD+) and an indole (EX527 analogue) reveals a novel mechanism of histone deacetylase inhibition
-
Zhao X, Allison D, Condon B, Zhang F, Gheyi T, et al. (2013) The 2.5 Å crystal structure of the SIRT1 catalytic domain bound to nicotinamide adenine dinucleotide (NAD+) and an indole (EX527 analogue) reveals a novel mechanism of histone deacetylase inhibition. J Med Chem 56: 963-969.
-
(2013)
J Med Chem
, vol.56
, pp. 963-969
-
-
Zhao, X.1
Allison, D.2
Condon, B.3
Zhang, F.4
Gheyi, T.5
-
27
-
-
78651177271
-
Energy-linked reduction of the mitochondrial nicotinamide-adenine
-
Szarkowska L, Erecinska M (1965) Energy-linked reduction of the mitochondrial nicotinamide-adenine. Acta Biochim Pol 12: 179-186.
-
(1965)
Acta Biochim Pol
, vol.12
, pp. 179-186
-
-
Szarkowska, L.1
Erecinska, M.2
-
28
-
-
33745867638
-
Poly(ADP-ribose): Novel functions for an old molecule
-
DOI 10.1038/nrm1963, PII NRM1963
-
Schreiber V, Dantzer F, Ame JC, de Murcia G (2006) Poly(ADP-ribose): novel functions for an old molecule. Nat Rev Mol Cell Biol 7: 517-528. (Pubitemid 44036457)
-
(2006)
Nature Reviews Molecular Cell Biology
, vol.7
, Issue.7
, pp. 517-528
-
-
Schreiber, V.1
Dantzer, F.2
Ame, J.-C.3
De Murcia, G.4
-
30
-
-
0021997074
-
Poly(ADP-ribose) in the cellular response to DNA damage
-
Berger NA (1985) Poly(ADP-ribose) in the cellular response to DNA damage. Radiat Res 101: 4-15.
-
(1985)
Radiat Res
, vol.101
, pp. 4-15
-
-
Berger, N.A.1
-
31
-
-
0022492499
-
DNA strand breaks, NAD metabolism, and programmed cell death
-
Carson DA, Seto S, Wasson DB, Carrera CJ (1986) DNA strand breaks, NAD metabolism, and programmed cell death. Exp Cell Res 164: 273-281. (Pubitemid 16042075)
-
(1986)
Experimental Cell Research
, vol.164
, Issue.2
, pp. 273-281
-
-
Carson, D.A.1
Seto, S.2
Wasson, D.B.3
Carrera, C.J.4
-
32
-
-
0024317904
-
Prevalence of Alzheimer's disease in a community population of older persons. Higher than previously reported
-
Evans DA, Funkenstein HH, Albert MS, Scherr PA, Cook NR, et al. (1989) Prevalence of Alzheimer's disease in a community population of older persons. Higher than previously reported JAMA 262: 2551-2556.
-
(1989)
JAMA
, vol.262
, pp. 2551-2556
-
-
Evans, D.A.1
Funkenstein, H.H.2
Albert, M.S.3
Scherr, P.A.4
Cook, N.R.5
-
33
-
-
0028338865
-
Prevalence of movement disorders in elderly community residents
-
Moghal S, Rajput AH, D'Arcy C, Rajput R (1994) Prevalence of movement disorders in elderly community residents. Neuroepidemiology 13: 175-178. (Pubitemid 24197317)
-
(1994)
Neuroepidemiology
, vol.13
, Issue.4
, pp. 175-178
-
-
Moghal, S.1
Rajput, A.H.2
D'Arcy, C.3
Rajput, R.4
-
34
-
-
0031881598
-
The neuropathology of alcohol-specific brain damage, or does alcohol damage the brain?
-
Harper C (1998) The neuropathology of alcohol-specific brain damage, or does alcohol damage the brain? J. Neuropathol Exp Neurol 57: 101-110.
-
(1998)
J. Neuropathol Exp Neurol
, vol.57
, pp. 101-110
-
-
Harper, C.1
-
35
-
-
84873056110
-
Alcohol-induced oxidative/nitrosative stress alters brain mitochondrial membrane properties
-
Reddy VD, Padmavathi P, Kavitha G, Saradamma B, Varadacharyulu N (2013) Alcohol-induced oxidative/nitrosative stress alters brain mitochondrial membrane properties. Mol Cell Biochem 375: 39-47.
-
(2013)
Mol Cell Biochem
, vol.375
, pp. 39-47
-
-
Reddy, V.D.1
Padmavathi, P.2
Kavitha, G.3
Saradamma, B.4
Varadacharyulu, N.5
-
36
-
-
0015888084
-
An improved cycling assay for nicotinamide adenine dinucleotide
-
Bernofsky C, Swan M (1973) An improved cycling assay for nicotinamide adenine dinucleotide. Anal Biochem 53: 452-458.
-
(1973)
Anal Biochem
, vol.53
, pp. 452-458
-
-
Bernofsky, C.1
Swan, M.2
-
37
-
-
0031930117
-
Murine glial cells regenerate NAD, after peroxide-induced depletion, using either nicotinic acid, nicotinamide, or quinolinic acid as substrates
-
Grant RS, Kapoor V (1998) Murine glial cells regenerate NAD, after peroxide induced depletion, using either nicotinic acid, nicotinamide, or quinolinic acid as substrates. J Neurochem 70: 1759-1763. (Pubitemid 28136993)
-
(1998)
Journal of Neurochemistry
, vol.70
, Issue.4
, pp. 1759-1763
-
-
Grant, R.S.1
Kapoor, V.2
-
38
-
-
0033105976
-
2- isoprostanes using gas chromatography-mass spectrometry
-
DOI 10.1006/abio.1998.3037
-
Mori TA, Croft KD, Puddey IB, Beilin LJ (1999) An improved method for the measurement of urinary and plasma F2-isoprostanes using gas chromatography-mass spectrometry. Anal Biochem 268: 117-125. (Pubitemid 29115518)
-
(1999)
Analytical Biochemistry
, vol.268
, Issue.1
, pp. 117-125
-
-
Mori, T.A.1
Croft, K.D.2
Puddey, I.B.3
Beilin, L.J.4
-
39
-
-
67749114631
-
Midlife serum cholesterol and increased risk of alzheimer's and vascular dementia three decades later
-
Solomon A, Kivipelto M, Wolozin B, Zhou J, Whitmer RA (2009) Midlife serum cholesterol and increased risk of alzheimer's and vascular dementia three decades later. Dement Geriatr Cogn Disord 28: 75-80.
-
(2009)
Dement Geriatr Cogn Disord
, vol.28
, pp. 75-80
-
-
Solomon, A.1
Kivipelto, M.2
Wolozin, B.3
Zhou, J.4
Whitmer, R.A.5
-
40
-
-
84855528737
-
Total and specific polyphenol intakes in midlife are associated with cognitive function measured 13 years later
-
Kesse-Guyot E, Fezeu L, Andreeva VA, Touvier M, Scalbert A, et al. (2012) Total and specific polyphenol intakes in midlife are associated with cognitive function measured 13 years later. J Nutr 142: 76-83.
-
(2012)
J Nutr
, vol.142
, pp. 76-83
-
-
Kesse-Guyot, E.1
Fezeu, L.2
Andreeva, V.A.3
Touvier, M.4
Scalbert, A.5
-
41
-
-
34147132771
-
Body mass index in midlife and risk of Alzheimer disease and vascular dementia
-
DOI 10.2174/156720507780362047
-
Whitmer RA, Gunderson EP, Quesenberry CP, Zhou J, Yaffe K (2007) Body mass index in midlife and risk of alzheimer disease and vascular dementia. Curr Alzheimer Res 4: 103-109. (Pubitemid 46557496)
-
(2007)
Current Alzheimer Research
, vol.4
, Issue.2
, pp. 103-109
-
-
Whitmer, R.A.1
Gunderson, E.P.2
Quesenberry Jr., C.P.3
Zhou, J.4
Yaffe, K.5
-
42
-
-
22144451172
-
The age-dependent relation of blood pressure to cognitive function and dementia
-
DOI 10.1016/S1474-4422(05)70141-1, PII S1474442205701411
-
Qiu C, Winblad B, Fratiglioni L (2005) The age-dependent relation of blood pressure to cognitive function and dementia. Lancet 4: 487-499. (Pubitemid 40982459)
-
(2005)
Lancet Neurology
, vol.4
, Issue.8
, pp. 487-499
-
-
Qiu, C.1
Winblad, B.2
Fratiglioni, L.3
-
43
-
-
0035964315
-
Does oxidative damage to DNA increase with age?
-
Hamilton Ml, Van Remmen H, Drake JA, Yang H, Guo Z, et al. (2001) Does oxidative damage to DNA increase with age? Proc Natl Acad Sci USA 98: 10469-10474.
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 10469-10474
-
-
Ml, H.1
Van Remmen, H.2
Drake, J.A.3
Yang, H.4
Guo, Z.5
-
44
-
-
0031909973
-
Enlarged and phagocytic, but not primed, interleukin-1́- immunoreactive microglia increase with age in normal human brain
-
DOI 10.1007/s004010050792
-
Sheng JG, Mrak RE, Griffin WST (1998) Enlarged and phagocytic, but not primed, interleukin-1á-immunoreactive microglia increase with age in normal human brain. Acta Neuropathol 95: 229-234. (Pubitemid 28120667)
-
(1998)
Acta Neuropathologica
, vol.95
, Issue.3
, pp. 229-234
-
-
Sheng, J.G.1
Mrak, R.E.2
Griffin, W.S.T.3
-
45
-
-
25444463296
-
+
-
+. Febs J 272: 4576-4589.
-
(2005)
Febs J
, vol.272
, pp. 4576-4589
-
-
Burkle, A.1
-
47
-
-
0035913903
-
SIRT1 functions as an NAD-dependent p53 deacetylase
-
DOI 10.1016/S0092-8674(01)00527-X
-
Vaziri H, Dessain SK, Ng Eaton E, Imai S I, Frye RA, et al. (2001) hSIR2(SIRT1) functions as an NAD dependent p53 deacetylase. Cell 107: 149-159. (Pubitemid 33035942)
-
(2001)
Cell
, vol.107
, Issue.2
, pp. 149-159
-
-
Vaziri, H.1
Dessain, S.K.2
Eaton, E.N.3
Imai, S.-I.4
Frye, R.A.5
Pandita, T.K.6
Guarente, L.7
Weinberg, R.A.8
-
48
-
-
12144290563
-
Stress-Dependent Regulation of FOXO Transcription Factors by the SIRT1 Deacetylase
-
DOI 10.1126/science.1094637
-
Brunet A, Sweeney LB, Sturgill JF, Chua KF, Greer PL, et al. (2004) Stress dependent regulation of FOXO transcription factors by the SIRT1 deacetylase. Science 303: 2011-2015. (Pubitemid 38393275)
-
(2004)
Science
, vol.303
, Issue.5666
, pp. 2011-2015
-
-
Brunet, A.1
Sweeney, L.B.2
Sturgill, J.F.3
Chua, K.F.4
Greer, P.L.5
Lin, Y.6
Tran, H.7
Ross, S.E.8
Mostoslavsy, R.9
Cohen, H.Y.10
Hu, L.S.11
Cheng, H.-L.12
Jedrychowski, M.P.13
Gygi, S.P.14
Sinclair, D.A.15
Alt, F.W.16
Greenberg, M.E.17
-
50
-
-
0030832874
-
Ischemic brain injury is mediated by the activation of poly(ADP- ribose)polymerase
-
Endres M, Wang ZQ, Namura S, Waeber C, Moskowitz MA (1997) Ischemic brain injury is mediated by the activation of poly(ADP-ribose)- polymerase. J Cereb Blood Flow Metab 17: 1143-1151. (Pubitemid 27514738)
-
(1997)
Journal of Cerebral Blood Flow and Metabolism
, vol.17
, Issue.11
, pp. 1143-1151
-
-
Endres, M.1
Wang, Z.-Q.2
Namura, S.3
Waeber, C.4
Moskowitz, M.A.5
-
51
-
-
3943092621
-
Pathways towards and away from Alzheimer's disease
-
Mattson MP (2004) Pathways towards and away from Alzheimer's disease. Nature 430: 631-639.
-
(2004)
Nature
, vol.430
, pp. 631-639
-
-
Mattson, M.P.1
-
52
-
-
65249173918
-
Nicotinamide prevents NAD1 depletion and protects neurons against excitotoxicity and cerebral ischemia: NAD1 consumption by SIRT1 may endanger energetically compromised neurons
-
Liu D, Gharavi R, Pitta M, Gleichmann M, Mattson MP (2009) Nicotinamide prevents NAD1 depletion and protects neurons against excitotoxicity and cerebral ischemia: NAD1 consumption by SIRT1 may endanger energetically compromised neurons. Neuromol Med 11: 28-42.
-
(2009)
Neuromol Med
, vol.11
, pp. 28-42
-
-
Liu, D.1
Gharavi, R.2
Pitta, M.3
Gleichmann, M.4
Mattson, M.P.5
-
53
-
-
0036246027
-
Bioavailability of reduced nicotinamide-adenin-dinucleotide (NADH) in the central nervous system of the anaesthetized rat measured by laser-induced fluorescence spectroscopy
-
DOI 10.1034/j.1600-0773.2002.900409.x
-
Rex A, Hentschke M-P, Fink H (2002) Bioavailability of reduced nicotinamide-adenin-dinucleotide (NADH) in the central nervous system of the anaesthetized rat measured by laser-induced fluorescence spectroscopy. Pharmacol Toxicol 90: 220-225. (Pubitemid 34478345)
-
(2002)
Pharmacology and Toxicology
, vol.90
, Issue.4
, pp. 220-225
-
-
Rex, A.1
Hentschke, M.-P.2
Fink, H.3
-
54
-
-
0014428566
-
Studies on the biosynthesis of nicotinamide-adenine dinucleotide in the brain
-
Deguchi T, Ichiyama A, Nishizuka Y, Hayaish O (1968) Studies on the biosynthesis of nicotinamide-adenine dinucleotide in the brain. Biochem Biophys Acta 158: 382-393.
-
(1968)
Biochem Biophys Acta
, vol.158
, pp. 382-393
-
-
Deguchi, T.1
Ichiyama, A.2
Nishizuka, Y.3
Hayaish, O.4
-
55
-
-
84859770335
-
Kynurenine pathway metabolism is involved in the maintenance of the intracellular NAD+ concentration in human primary astrocytes
-
Grant R, Nguyen S, Guillemin G (2010) Kynurenine pathway metabolism is involved in the maintenance of the intracellular NAD+ concentration in human primary astrocytes. Int J Tryp Res 3: 151-156.
-
(2010)
Int J Tryp Res
, vol.3
, pp. 151-156
-
-
Grant, R.1
Nguyen, S.2
Guillemin, G.3
-
56
-
-
0032937340
-
Hippocampal volume in patients with alcohol dependence
-
Agartz I, Momenan R, Rawlings RR, Kerich MJ, Hommer DW (1999) Hippocampal volume in patients with alcohol dependence. Arch Gen Psychiatry 56: 356-363. (Pubitemid 29165182)
-
(1999)
Archives of General Psychiatry
, vol.56
, Issue.4
, pp. 356-363
-
-
Agartz, I.1
Momenan, R.2
Rawlings, R.R.3
Kerich, M.J.4
Hommer, D.W.5
-
57
-
-
0347356532
-
Alcohol Intake and Cerebral Abnormalities on Magnetic Resonance Imaging in A Community-Based Population of Middle-Aged Adults: The Atherosclerosis Risk in Communities (ARIC) Study
-
DOI 10.1161/01.STR.0000105929.88691.8E
-
Ding J, Eigenbrodt ML, Mosley TH Jr, Hutchinson RG, Folsom AR, et al. (2004) Alcohol intake and cerebral abnormalities on magnetic resonance imaging in a community based sample of middle-aged adults: the arteriosclerosis risk in communities (ARIC) study. Stroke 35: 16-21. (Pubitemid 38057582)
-
(2004)
Stroke
, vol.35
, Issue.1
, pp. 16-21
-
-
Ding, J.1
Eigenbrodt, M.L.2
Mosley Jr., T.H.3
Hutchinson, R.G.4
Folsom, A.R.5
Harris, T.B.6
Nieto, F.J.7
-
58
-
-
13544267512
-
Association between reported alcohol intake and cognition: Results from the women's health initiative memory study
-
DOI 10.1093/aje/kwi043
-
Espeland MA, Gu L, Masaki KH, Langer RD, Coker LH, et al. (2005) Association between reported alcohol intake and cognition: results from the women's health initiative memory study. Am J Epidemiol 161: 228-238. (Pubitemid 40223511)
-
(2005)
American Journal of Epidemiology
, vol.161
, Issue.3
, pp. 228-238
-
-
Espeland, M.A.1
Gu, L.2
Masaki, K.H.3
Langer, R.D.4
Coker, L.H.5
Stefanick, M.L.6
Ockene, J.7
Rapp, S.R.8
-
59
-
-
1842632618
-
Alcohol intake and risk of dementia
-
Luchsinger JA, Tang MX, Siddiqui M, Shea S, Mayeux R. Alcohol intake and risk of dementia (2004) J Am Geriatr Soc 52: 540-546.
-
(2004)
J Am Geriatr Soc
, vol.52
, pp. 540-546
-
-
Luchsinger, J.A.1
Tang, M.X.2
Siddiqui, M.3
Shea, S.4
Mayeux, R.5
-
60
-
-
67649749221
-
Chronic effects of low to moderate alcohol consumption on structural and functional properties of the brain: Beneficial or not?
-
Verbaten MN (2009) Chronic effects of low to moderate alcohol consumption on structural and functional properties of the brain: beneficial or not? Hum Psychopharmacol Clin Exp 24: 199-205.
-
(2009)
Hum Psychopharmacol Clin Exp
, vol.24
, pp. 199-205
-
-
Verbaten, M.N.1
-
61
-
-
0028902051
-
Mutations in the cell adhesion molecule L1 cause mental retardation
-
Wong EV, Kenwrick S, Willems P, Lemmon V (1995) Mutations in the cell adhesion molecule L1 cause mental retardation. Trends Neurosci 18: 168-172.
-
(1995)
Trends Neurosci
, vol.18
, pp. 168-172
-
-
Wong, E.V.1
Kenwrick, S.2
Willems, P.3
Lemmon, V.4
-
62
-
-
0030011975
-
Alcohol inhibits cell-cell adhesion mediated by human L1
-
DOI 10.1083/jcb.133.2.381
-
Ramanathan R, Wilkemeyer MF, Mittal B, Perides G, Charness ME (1996) Alcohol inhibits cell-cell adhesion mediated by human L1. J Cell Biol 133: 381-390. (Pubitemid 26132536)
-
(1996)
Journal of Cell Biology
, vol.133
, Issue.2
, pp. 381-390
-
-
Ramanathan, R.1
Wilkemeyer, M.F.2
Mittal, B.3
Perides, G.4
Charness, M.E.5
-
63
-
-
0033844602
-
Alcohol exposure alters the expression pattern of neural cell adhesion molecules during brain development
-
DOI 10.1046/j.1471-4159.2000.0750954.x
-
Minana R, Climent E, Barettino D, Segui JM, Renau-Piqueras J, et al. (2000) Alcohol exposure alters the expression pattern of neural cell adhesion molecules during brain development. J Neurochem 75: 954-964. (Pubitemid 30660483)
-
(2000)
Journal of Neurochemistry
, vol.75
, Issue.3
, pp. 954-964
-
-
Minana, R.1
Climent, E.2
Barettino, D.3
Segui, J.M.4
Renau-Piqueras, J.5
Guerri, C.6
-
64
-
-
84855281868
-
Mechanisms of alcohol-induced endoplasmic reticulum stress and organ injuries
-
Ji C (2012) Mechanisms of alcohol-induced endoplasmic reticulum stress and organ injuries. Biochem Res Int: art no 216450.
-
(2012)
Biochem Res Int
, pp. 216450
-
-
Ji, C.1
-
65
-
-
80051904574
-
Pharmacological activation/inhibition of the cannabinoid system affects alcohol withdrawal-induced neuronal hypersensitivity to excitotoxic insults
-
Rubio M, Villain H, Docagne F, Roussel BD, Ramos JA, et al. (2011) Pharmacological activation/inhibition of the cannabinoid system affects alcohol withdrawal-induced neuronal hypersensitivity to excitotoxic insults. PLoS ONE 6: art no e23690.
-
(2011)
PLoS ONE
, vol.6
-
-
Rubio, M.1
Villain, H.2
Docagne, F.3
Roussel, B.D.4
Ramos, J.A.5
-
66
-
-
0027220442
-
Effects of in utero administration of alcohol on glutathione levels in brain and liver
-
Reyes E, Ott S, Robinson B (1993) Effects of in utero administration of alcohol on glutathione levels in brain and liver. Alcohol Clin Exp Res 17: 877-881. (Pubitemid 23249039)
-
(1993)
Alcoholism: Clinical and Experimental Research
, vol.17
, Issue.4
, pp. 877-881
-
-
Reyes, E.1
Ott, S.2
Robinson, B.3
-
67
-
-
56049117834
-
Mechanism of alcohol-induced oxidative stress and neuronal injury
-
Haorah J, Ramirez SH, Floreani N, Gorantla S, Morsey B, et al. (2008) Mechanism of alcohol-induced oxidative stress and neuronal injury. Free Radic Biol Med 45: 1542-1550.
-
(2008)
Free Radic Biol Med
, vol.45
, pp. 1542-1550
-
-
Haorah, J.1
Ramirez, S.H.2
Floreani, N.3
Gorantla, S.4
Morsey, B.5
-
68
-
-
28844498785
-
Alcohol-induced oxidative stress in brain endothelial cells causes blood-brain barrier dysfunction
-
DOI 10.1189/jlb.0605340
-
Haorah J, Knipe B, Leibhart J, Ghorpade A, Persidsky Y (2005) Alcohol-induced oxidative stress in brain endothelial cells causes blood-brain barrier dysfunction. J Leukoc Biol 78: 1223-1232. (Pubitemid 41779228)
-
(2005)
Journal of Leukocyte Biology
, vol.78
, Issue.6
, pp. 1223-1232
-
-
Haorah, J.1
Knipe, B.2
Leibhart, J.3
Ghorpade, A.4
Persidsky, Y.5
-
69
-
-
38949188640
-
Lipid rafts regulate ethanol-induced activation of TLR4 signaling in murine macrophages
-
DOI 10.1016/j.molimm.2007.10.025, PII S0161589007008176
-
Fernandez-Lizarbe S, Pascual M, Gascon MS, Blanco A, Guerri C (2008) Lipid rafts regulate ethanol-induced activation of TLR4 signaling in murine macrophages. Mol Immunol 45: 2007-2016. (Pubitemid 351226271)
-
(2008)
Molecular Immunology
, vol.45
, Issue.7
, pp. 2007-2016
-
-
Fernandez-Lizarbe, S.1
Pascual, M.2
Gascon, M.S.3
Blanco, A.4
Guerri, C.5
-
70
-
-
27744562724
-
Involvement of TLR4/type I IL-1 receptor signaling in the induction of inflammatory mediators and cell death induced by ethanol in cultured astrocytes
-
Blanco AM, Valles SL, Pascual M, Guerri C (2005) Involvement of TLR4/type I IL-1 receptor signaling in the induction of inflammatory mediators and cell death induced by ethanol in cultured astrocytes. J Immunol 175: 6893-6899. (Pubitemid 41599911)
-
(2005)
Journal of Immunology
, vol.175
, Issue.10
, pp. 6893-6899
-
-
Blanco, A.M.1
Valles, S.L.2
Pascual, M.3
Guerri, C.4
-
71
-
-
0020600287
-
+) levels in Drosophila
-
McElfresh KC, McDonald JF (1983) The effect of alcohol stress on nicotinamide adenine dinucleotide (NAD+) levels in Drosophila. Biochem Gen 21: 365-374. (Pubitemid 13085444)
-
(1983)
Biochemical Genetics
, vol.21
, Issue.3-4
, pp. 365-374
-
-
McElfresh, K.C.1
McDonald, J.F.2
|