Insulin-sensitizing effect of LXR agonist T0901317 in high-fat fed rats is associated with restored muscle GLUT4 expression and insulin-stimulated AS160 phosphorylation

Cellular Physiology and Biochemistry

Volumn 33, Issue 4, 2014, Pages 1047-1057

  Baranowski, Marcin ^a   Zabielski, Piotr ^a   Błachnio Zabielska, Agnieszka U ^a   Harasim, Ewa ^a   Chabowski, Adrian ^a   Górski, Jan ^a  

^a MEDICAL UNIVERSITY OF BIALYSTOK   (Poland)

Author keywords

Akt PKB; Insulin resistance; IRS1; Lipid mediators; Skeletal muscle

Indexed keywords

CERAMIDE; DIACYLGLYCEROL; FATTY ACID; GLUCOSE; GLUCOSE TRANSPORTER 4; INSULIN; LIVER X RECEPTOR; MESSENGER RNA; N (2,2,2 TRIFLUOROETHYL) N [4 (2,2,2 TRIFLUORO 1 HYDROXY 1 TRIFLUOROMETHYLETHYL)PHENYL]BENZENESULFONAMIDE; PROTEIN KINASE B; TRIACYLGLYCEROL; PROTEIN; PROTEIN AS160; UNCLASSIFIED DRUG; ACYL COENZYME A DESATURASE; FLUORINATED HYDROCARBON; GLUCOSE TRANSPORTER 1; GUANOSINE TRIPHOSPHATASE ACTIVATING PROTEIN; LOC686547 PROTEIN, RAT; ORPHAN NUCLEAR RECEPTOR; STEROL REGULATORY ELEMENT BINDING PROTEIN 1; SULFONAMIDE; TO-901317;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTIDIABETIC ACTIVITY; ARTICLE; CONTROLLED STUDY; ENZYME PHOSPHORYLATION; FATTY ACID BLOOD LEVEL; GASTROCNEMIUS MUSCLE; GLUCONEOGENESIS; GLUCOSE BLOOD LEVEL; GLUCOSE TOLERANCE; GLUCOSE TOLERANCE TEST; GLUCOSE TRANSPORT; INSULIN BLOOD LEVEL; INSULIN RESISTANCE; INSULIN SENSITIVITY; INSULIN TOLERANCE TEST; LIPID DIET; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; REAL TIME POLYMERASE CHAIN REACTION; SOLEUS MUSCLE; TRIACYLGLYCEROL BLOOD LEVEL; WESTERN BLOTTING; ANIMAL MODEL; HYPERLIPIDEMIA; INSULIN SENSITIZATION; MUSCLE METABOLISM; PROTEIN PHOSPHORYLATION; SENSITIZATION; WISTAR RAT; AGONISTS; ANIMAL; DRUG EFFECTS; HYPERLIPIDEMIAS; METABOLISM; PHOSPHORYLATION; SKELETAL MUSCLE;

ANIMALIA; RATTUS; RATTUS NORVEGICUS; RODENTIA;

ANIMALS; CERAMIDES; DIET, HIGH-FAT; DIGLYCERIDES; GLUCOSE TOLERANCE TEST; GLUCOSE TRANSPORTER TYPE 1; GLUCOSE TRANSPORTER TYPE 4; GTPASE-ACTIVATING PROTEINS; HYDROCARBONS, FLUORINATED; HYPERLIPIDEMIAS; INSULIN; MALE; MUSCLE, SKELETAL; ORPHAN NUCLEAR RECEPTORS; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS C-AKT; RATS; RATS, WISTAR; STEAROYL-COA DESATURASE; STEROL REGULATORY ELEMENT BINDING PROTEIN 1; SULFONAMIDES;

EID: 84897968483     PISSN: 10158987     EISSN: 14219778     Source Type: Journal    
DOI: 10.1159/000358675     Document Type: Article

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