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Volumn 63, Issue 5, 2014, Pages 707-709

Fbxw7 hotspot mutations and human colon cancer: Mechanistic insights from new mouse models

Author keywords

[No Author keywords available]

Indexed keywords

ONCOPROTEIN; PROTEIN FBXW7; UNCLASSIFIED DRUG;

EID: 84897965636     PISSN: 00175749     EISSN: 14683288     Source Type: Journal    
DOI: 10.1136/gutjnl-2013-305144     Document Type: Note
Times cited : (13)

References (10)
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  • 3
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    • A continuum model for tumour suppression
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  • 4
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    • Retention of wild-type p53 in tumors from p53 heterozygous mice: Reduction of p53 dosage can promote cancer formation
    • DOI 10.1093/emboj/17.16.4657
    • Venkatachalam S, Shi YP, Jones SN, et al. Retention of wild-type p53 in tumors from p53 heterozygous mice: reduction of p53 dosage can promote cancer formation. EMBO J 1998;17:4657-67. (Pubitemid 28377166)
    • (1998) EMBO Journal , vol.17 , Issue.16 , pp. 4657-4667
    • Venkatachalam, S.1    Shi, Y.-P.2    Jones, S.N.3    Vogel, H.4    Bradley, A.5    Pinkel, D.6    Donehower, L.A.7
  • 5
    • 77951765345 scopus 로고    scopus 로고
    • Subtle variations in Pten dose determine cancer susceptibility
    • Alimonti A, Carracedo A, Clohessy JG, et al. Subtle variations in Pten dose determine cancer susceptibility. Nat Genet 2010;42:454-8.
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    • Alimonti, A.1    Carracedo, A.2    Clohessy, J.G.3
  • 6
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    • FBW7 ubiquitin ligase: A tumour suppressor at the crossroads of cell division, growth and differentiation
    • DOI 10.1038/nrc2290, PII NRC2290
    • Welcker M, Clurman BE. FBW7 ubiquitin ligase: a tumour suppressor at the crossroads of cell division, growth and differentiation. Nat Rev Cancer 2008;8:83-93. (Pubitemid 351161321)
    • (2008) Nature Reviews Cancer , vol.8 , Issue.2 , pp. 83-93
    • Welcker, M.1    Clurman, B.E.2
  • 8
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    • CDC4/FBXW7 and the 'just enough' model of tumourigenesis
    • Davis H, Tomlinson I. CDC4/FBXW7 and the 'just enough' model of tumourigenesis. J Pathol 2012;227:131-5.
    • (2012) J Pathol , vol.227 , pp. 131-135
    • Davis, H.1    Tomlinson, I.2
  • 9
    • 84897959817 scopus 로고    scopus 로고
    • Investigation of the atypical FBXW7 mutation spectrum in human tumours by conditional expression of a heterozygous propellor tip missense allele in the mouse intestines
    • Davis H, Lewis A, Behrens A, et al. Investigation of the atypical FBXW7 mutation spectrum in human tumours by conditional expression of a heterozygous propellor tip missense allele in the mouse intestines. Gut 2014;63:792-9.
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    • Davis, H.1    Lewis, A.2    Behrens, A.3
  • 10
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    • Loss of FBXW7, a cell cycle regulating gene, in colorectal cancer: Clinical significance
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    • Iwatsuki, M.1    Mimori, K.2    Ishii, H.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.