Nitric oxide and iron metabolism in exercised rat with L-arginine supplementation

Molecular and Cellular Biochemistry

Volumn 252, Issue 1-2, 2003, Pages 65-72

  Xiao, De Sheng ^a   Jiang, Lu ^a   Che, Li Long ^a   Lu, Liwei ^b  

^a JIANGSU UNIVERSITY   (China)

^b UNIVERSITY OF HONG KONG   (Hong Kong)

Author keywords

Arginine; Exercise; Iron metabolism; Nitric oxide

Indexed keywords

ARGININE; DRINKING WATER; IRON; NITRATE; NITRIC OXIDE; NITRITE; NONHEME IRON PROTEIN;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BONE MARROW CELL; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DIET SUPPLEMENTATION; EXERCISE; FEMALE; HEART; IRON METABOLISM; IRON STORAGE; KIDNEY PARENCHYMA; LIVER PARENCHYMA; NONHUMAN; RAT; SITTING; SPLEEN; SWIMMING;

ANIMALIA;

EID: 0141839822     PISSN: 03008177     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1025517216681     Document Type: Article

References (28)

1. Newhouse IJ, Clement DB: Iron status in athletes: An update. Sports Med 5: 337-352, 1988
2. Xiao DS, Qian ZM: Plasma nitric oxide and iron concentrations in exercised rats are negatively correlated. Mol Cell Biochem 208: 163-166, 2000
3. Qian ZM, Xiao DS, Ke Y, Liao QK: Increased nitric oxide is one of the causes of changes of iron metabolism in strenuously exercised rats. Am J Physiol 280: R739-743, 2001
4. Ho KP, Xiao DS, Ke Y, Qian ZM: Exercise decreases cytosolic aconitase activity in the liver, spleen, and bone marrow in rats. Biochem Biophys Res Commun 282: 262-267, 2001
5. Penttinen J, Toyry J, Eerikainen S, Litmanen H, Rinkinen T, Lansimies E: Does plasma L-arginine level play a role in regulation of blood pressure during exercise and autonomic nervous function? Clin Physiol 18: 539-543, 1998
6. Litvinova L, Viru A: Effect of exercise and adrenal insufficiency on urea production in rats. Eur J Appl Physiol 70: 536-540, 1995
7. Viru A, Litvinova L, Viru M, Smirnova T: Glucocorticoids in metabolic control during exercise: Alanine metabolism. J Appl Physiol 76: 801-805, 1994
8. Murray-Rust J, Leiper J, McAlister M, Phelan J, Tilley S, Santa Maria J, Vallance P, McDonald N: Structural insights into the hydrolysis of cellular nitric oxide synthase inhibitors by dimethylarginine dimethylaminohydrolase. Nat Struct Biol 8: 679-683, 2001
9. Birdsey GM, Leiper JM, Vallance P: Intracellular localization of dimethylarginine dimethylaminohydrolase overexpressed in an endothelial cell line. Acta Physiol Scand 168: 73-79, 2000
10. Leiper J, Vallance P: Biological significance of endogenous methylarginines that inhibit nitric oxide synthases. Cardiovasc Res 43: 542-548, 1999
11. Böger RH, Bode-Boger SM, Thiele W, Creutzig A, Alexander K, Frolich JC: Restoring vascular nitric oxide formation by L-arginine improves the symptoms of intermittent claudication in patients with peripheral arterial occlusive disease. J Am Coll Cardiol 32: 1336-1344, 1998
12. Maxwell AJ, Ho HV, Le CQ, Lin PS, Bernstein D, Cooke JP: L-arginine enhances aerobic exercise capacity in association with augmented nitric oxide production. J Appl Physiol 90: 933-938, 2001
13. Qian ZM, Xiao DS, Tang PL, Yao FY, Liao QK: Increased expression of transferrin receptor on membrane of erythroblasts in strenuously exercised rats. J Appl Physiol 87: 523-529, 1999
14. Qian ZM, Xiao DS, Tang PL: Changes of transferrin-free iron uptake by bone marrow erythroblasts in strenuously exercised rats. J Nutr Biochem 11: 367-373, 2000
15. Qian ZM, Xiao DS, Liao QK, Ho KP: Effect of different durations of exercise on transferrin-bound iron uptake by rat erythroblast. J Nutr Biochem 13: 47-54, 2002
16. Gutteridge JM, Rowley DA, Halliwell B, Cooper DF, Heeley DM: Copper and iron complexes catalytic for oxygen radical reactions in sweat from human athletes. Clin Chim Acta 145: 267-273, 1985
17. Burkitt MJ, Milne L, Raafat A: A simple, highly sensitive and improved method for the measurement of bleomycin-detectable iron: The 'catalytic iron index' and its value in the assessment of iron status in haemochromatosis. Clin Sci 100: 239-247, 2001
18. Davies MG, Fulton GJ, Hagen PO: Clinical biology of nitric oxide. Br J Surg 82: 1598-1610, 1995
19. Tsikas D, Boger RH, Sandmann J, Bode-Boger SM, Frolich JC: Endogenous nitric oxide synthase inhibitors are responsible for the L-arginine paradox. FEBS Lett 478: 1-3, 2000
20. Cai Z, Xin J, Pollock DM, Pollock JS: Shear stress-mediated NO production in inner medullary collecting duct cells. Am J Physiol 279: F270-274, 2000
21. Morgan EH, Baker E: Iron uptake and metabolism by hepatocytes. Fed Proc 45: 2810-2816, 1986
22. Ponka P, Beaumont C, Richardson DR: Function and regulation of transferrin and ferritin. Semin Hematol 35: 35-54, 1988
23. Bezkorovainy A: Biochemistry of nonheme iron in man. I. Iron proteins and cellular iron metabolism. Clin Physiol Biochem 7: 1-17, 1989
24. Ahluwalia N, Gordon MA, Handte G, Mahlon M, Li NQ, Beard JL, Weinstock D, Ross AC: Iron status and stores decline with age in Lewis rats. J Nutr 130: 2378-2383, 2000
25. Eisenstein RS: Iron regulatory proteins and the molecular control of mammalian iron metabolism. Annu Rev Nutr 20: 627-662, 2000
26. Reif DW, Simmons RD: Nitric oxide mediates iron release from ferritin. Arch Biochem Biophys 283: 537-541, 1990
27. Xiao DS, Qian ZM: Changes in the iron uptake of bone marrow cells in exercised rats. Acta Physiol Sin 52: 147-151, 2000
28. Juckett M, Zheng Y, Yuan H, Pastor T, Antholine W, Weber M, Vercellotti G: Heme and the endothelium: Effects of nitric oxide on catalytic iron and heme, degradation by heme oxygenase. J Biol Chem 273: 23388-23397, 1998