Ablating spinal nk1-bearing neurons eliminates the development of pain and reduces spinal neuronal hyperexcitability and inflammation from mechanical joint injury in the rat

Journal of Pain

Volumn 15, Issue 4, 2014, Pages 378-386

  Weisshaar, Christine L ^a   Winkelstein, Beth A ^a,b  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

joint; Pain; saporin; spinal cord; substance P

Indexed keywords

CYTOKINE; GLIAL FIBRILLARY ACIDIC PROTEIN; INTERLEUKIN 1ALPHA; NEUROKININ 1 RECEPTOR; NEUROTOXIN; SAPORIN; SUBSTANCE P;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CYTOKINE RELEASE; HYPERALGESIA; IMMUNOHISTOCHEMISTRY; INFLAMMATION; JOINT INJURY; NERVE CELL; NERVE CELL EXCITABILITY; NERVE CELL PLASTICITY; NOCICEPTION; NONHUMAN; PAIN; RAT; SPINAL CORD; ANIMAL; ARTHRALGIA; CENTRAL NERVOUS SYSTEM SENSITIZATION; DISEASE MODEL; ELECTROPHYSIOLOGY; GLIA; MALE; METABOLISM; PHYSIOLOGY; POSTERIOR HORN CELL; SPRAGUE DAWLEY RAT; ZYGAPOPHYSEAL JOINT;

ANIMALS; ARTHRALGIA; CENTRAL NERVOUS SYSTEM SENSITIZATION; DISEASE MODELS, ANIMAL; ELECTROPHYSIOLOGY; IMMUNOHISTOCHEMISTRY; INFLAMMATION; MALE; NEUROGLIA; NEURONAL PLASTICITY; NEURONS; PAIN; POSTERIOR HORN CELLS; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, NEUROKININ-1; ZYGAPOPHYSEAL JOINT;

EID: 84897954342     PISSN: 15265900     EISSN: 15288447     Source Type: Journal    
DOI: 10.1016/j.jpain.2013.12.003     Document Type: Article

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