Biodistribution and radiation dosimetry of deuterium-substituted 18F-fluoromethyl-[1, 2-2H4]choline in healthy volunteers

Journal of Nuclear Medicine

Volumn 55, Issue 2, 2014, Pages 256-263

  Challapalli, Amarnath ^a   Sharma, Rohini ^b   Hallett, William A ^c   Kozlowski, Kasia ^a   Carroll, Laurence ^a   Brickute, Diana ^a   Twyman, Frazer ^a   Al Nahhas, Adil ^d   Aboagye, Eric O ^a  

^a HAMMERSMITH HOSPITAL   (United Kingdom)

^b IMPERIAL COLLEGE LONDON   (United Kingdom)

^c Imanova Ltd   (United Kingdom)

^d IMPERIAL COLLEGE HEALTHCARE NHS TRUST   (United Kingdom)

Author keywords

Biodistribution; Dosimetry

Indexed keywords

FLUOROMETHYL[1, 2 DEUTERIUM 4]CHOLINE F 18; TRACER; UNCLASSIFIED DRUG; CHOLINE; DEUTERIUM; DRUG DERIVATIVE; FLUORINE; FLUOROMETHYLCHOLINE; RADIOPHARMACEUTICAL AGENT;

ADULT; AGED; AREA UNDER THE CURVE; ARTICLE; BLOOD SAMPLING; DOSIMETRY; DRUG DISTRIBUTION; DRUG ELIMINATION; DRUG METABOLISM; DRUG SAFETY; DRUG STRUCTURE; DRUG TOLERABILITY; FEMALE; HUMAN; HUMAN EXPERIMENT; MALE; MEAN RESIDENCE TIME; NORMAL HUMAN; POSITRON EMISSION TOMOGRAPHY; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; UNSPECIFIED SIDE EFFECT; URINALYSIS; 18F-D4-FCH; BIODISTRIBUTION; COMPUTER ASSISTED TOMOGRAPHY; IMAGE PROCESSING; METHODOLOGY; MIDDLE AGED; MULTIMODAL IMAGING; PATIENT SAFETY; RADIATION DOSE; RADIOMETRY; SEX DIFFERENCE; TISSUE DISTRIBUTION; WHOLE BODY IMAGING;

18F-D4-FCH; BIODISTRIBUTION; DOSIMETRY;

AGED; CHOLINE; DEUTERIUM; FEMALE; FLUORINE RADIOISOTOPES; HEALTHY VOLUNTEERS; HUMANS; IMAGE PROCESSING, COMPUTER-ASSISTED; MALE; MIDDLE AGED; MULTIMODAL IMAGING; PATIENT SAFETY; POSITRON-EMISSION TOMOGRAPHY; RADIATION DOSAGE; RADIOMETRY; RADIOPHARMACEUTICALS; SEX FACTORS; TISSUE DISTRIBUTION; TOMOGRAPHY, X-RAY COMPUTED; WHOLE BODY IMAGING;

EID: 84897939845     PISSN: 01615505     EISSN: None     Source Type: Journal    
DOI: 10.2967/jnumed.113.129577     Document Type: Article

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