Inhibition of malignant phenotypes of human osteosarcoma cells by a gene silencer, a pyrrole-imidazole polyamide, which targets an E-box motif

FEBS Open Bio

Volumn 4, Issue , 2014, Pages 328-334

  Taniguchi, Masashi ^a   Fujiwara, Kyoko ^a   Nakai, Yuji ^b   Ozaki, Toshinori ^c   Koshikawa, Nobuko ^c   Toshio, Kojima ^a   Kataba, Motoaki ^a   Oguni, Asako ^a   Matsuda, Hiroyuki ^a   Yoshida, Yukihiro ^a   Tokuhashi, Yasuaki ^a   Fukuda, Noboru ^a   Ueno, Takahiro ^a   Soma, Masayoshi ^a   Nagase, Hiroki ^c  

^a NIHON UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b UNIVERSITY OF TOKYO   (Japan)

^c CHIBA CANCER CENTER   (Japan)

Author keywords

c MYC; E box; MALAT1; MG63 cells; Osteosarcoma; Pyrrole imidazole polyamide

Indexed keywords

GELATINASE B; IMIDAZOLE; LONG UNTRANSLATED RNA; METASTASIS ASSOCIATED LUNG ADENOCARCINOMA TRANSCRIPT 1; MYC PROTEIN; POLYAMIDE; PYRROLE; SMALL INTERFERING RNA; TUMOR PROTEIN; UNCLASSIFIED DRUG; ANTINEOPLASTIC AGENT; CASPASE 3; IMIDAZOLE DERIVATIVE; MYC 6 POLYAMIDE; PYRROLE DERIVATIVE;

ADHERENT CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CANCER INHIBITION; CANCER SIZE; CELL GROWTH; CELL VIABILITY; DNA CONTENT; E BOX ELEMENT; G1 PHASE CELL CYCLE CHECKPOINT; GENE AMPLIFICATION; GENE OVEREXPRESSION; GENE SILENCING; GENE TARGETING; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; MALE; METASTASIS; MOUSE; NONHUMAN; OSTEOSARCOMA CELL; PRIORITY JOURNAL; REAL TIME POLYMERASE CHAIN REACTION; SILENCER GENE; TUMOR XENOGRAFT; WST-8 ASSAY; ANIMAL CELL; CELL LYSATE; CHEMICAL STRUCTURE; CONTROLLED STUDY; DOWN REGULATION; DRUG DESIGN; GENE; GROWTH INHIBITION; IMMUNOBLOTTING; MALAT 1 GENE; MICROARRAY ANALYSIS; PHENOTYPE; TUMOR GROWTH; TUMOR VOLUME;

EID: 84897934774     PISSN: 22115463     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.fob.2014.03.004     Document Type: Article

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