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Volumn 17, Issue 3, 2014, Pages 485-490

Methylenetetrahydrofolate reductase (MTHFR) 677C/T polymorphism is associated with antipsychotic-induced weight gain in first-episode schizophrenia

Author keywords

Antipsychotic; Genotype; MTHFR polymorphism; Schizophrenia; Weight gain

Indexed keywords

CHLORPROMAZINE; CLOZAPINE; HALOPERIDOL; NEUROLEPTIC AGENT; OLANZAPINE; QUETIAPINE; RISPERIDONE; SULPIRIDE; ZIPRASIDONE;

EID: 84897901955     PISSN: 14611457     EISSN: 14695111     Source Type: Journal    
DOI: 10.1017/S1461145713001375     Document Type: Article
Times cited : (14)

References (25)
  • 1
    • 84862244727 scopus 로고    scopus 로고
    • DNA methylation in schizophrenia subjects: Gender and MTHFR 677C/T genotype differences
    • Burghardt KJ, Pilsner JR, Bly MJ, Ellingrod VL (2012) DNA methylation in schizophrenia subjects: gender and MTHFR 677C/T genotype differences. Epigenomics 4:261-268.
    • (2012) Epigenomics , vol.4 , pp. 261-268
    • Burghardt, K.J.1    Pilsner, J.R.2    Bly, M.J.3    Ellingrod, V.L.4
  • 3
    • 77957875122 scopus 로고    scopus 로고
    • C-reactive protein, vitamin B12 and C677T polymorphism of N-5,10-methylenetetrahydrofolate reductase gene are related to insulin resistance and risk factors for metabolic syndrome in Chinese population
    • Chen AR, Zhang HG, Wang ZP (2010) C-reactive protein, vitamin B12 and C677T polymorphism of N-5,10-methylenetetrahydrofolate reductase gene are related to insulin resistance and risk factors for metabolic syndrome in Chinese population. Clin Invest Med 33:E290-E297.
    • (2010) Clin Invest Med , vol.33
    • Chen, A.R.1    Zhang, H.G.2    Wang, Z.P.3
  • 5
    • 36849066949 scopus 로고    scopus 로고
    • Metabolic syndrome and insulin resistance in schizophrenia patients receiving antipsychotics genotyped for the methylenetetrahydrofolate reductase (MTHFR) 677C/T and 1298A/C variants
    • Ellingrod VL, Miller DD, Taylor SF, Moline J, Holman T, Kerr J (2008) Metabolic syndrome and insulin resistance in schizophrenia patients receiving antipsychotics genotyped for the methylenetetrahydrofolate reductase (MTHFR) 677C/T and 1298A/C variants. Schizophr Res 98:47-54.
    • (2008) Schizophr Res , vol.98 , pp. 47-54
    • Ellingrod, V.L.1    Miller, D.D.2    Taylor, S.F.3    Moline, J.4    Holman, T.5    Kerr, J.6
  • 6
    • 84857911892 scopus 로고    scopus 로고
    • Risk factors associated with metabolic syndrome in bipolar and schizophrenia subjects treated with antipsychotics: The role of folate pharmacogenetics
    • Ellingrod VL, Taylor SF, Dalack G, Grove TB, Bly MJ, Brook RD, Zöllner SK, Pop-Busui R (2012) Risk factors associated with metabolic syndrome in bipolar and schizophrenia subjects treated with antipsychotics: the role of folate pharmacogenetics. J Clin Psychopharmacol 32:261-265.
    • (2012) J Clin Psychopharmacol , vol.32 , pp. 261-265
    • Ellingrod, V.L.1    Taylor, S.F.2    Dalack, G.3    Grove, T.B.4    Bly, M.J.5    Brook, R.D.6    Zöllner, S.K.7    Pop-Busui, R.8
  • 7
    • 0036328453 scopus 로고    scopus 로고
    • Gene-nutrient interactions and DNA methylation
    • Friso S, Choi SW (2002) Gene-nutrient interactions and DNA methylation. J Nutr 132 (Suppl. 8):2382S-2387S.
    • (2002) J Nutr , vol.132 SUPPL.8
    • Friso, S.1    Choi, S.W.2
  • 10
    • 33947310031 scopus 로고    scopus 로고
    • Environmental epigenomics and disease susceptibility
    • Jirtle RL, Skinner MK (2007) Environmental epigenomics and disease susceptibility. Nat Rev Genet 8:253-262.
    • (2007) Nat Rev Genet , vol.8 , pp. 253-262
    • Jirtle, R.L.1    Skinner, M.K.2
  • 11
    • 84862022001 scopus 로고    scopus 로고
    • Association of the MTHFR gene with antipsychotic-induced metabolic abnormalities in patients with schizophrenia
    • Kuzman MR, Müller DJ (2012) Association of the MTHFR gene with antipsychotic-induced metabolic abnormalities in patients with schizophrenia. Pharmacogenomics 13:843-846.
    • (2012) Pharmacogenomics , vol.13 , pp. 843-846
    • Kuzman, M.R.1    Müller, D.J.2
  • 12
    • 33645527632 scopus 로고    scopus 로고
    • The thermolabile variant of MTHFR is associated with depression in the BritishWomen's Heart and Health Study and a meta-analysis
    • Lewis SJ, Lawlor DA, Davey Smith G, Araya R, Timpson N, Day IN, Ebrahim S (2006) The thermolabile variant of MTHFR is associated with depression in the BritishWomen's Heart and Health Study and a meta-analysis. Mol Psychiatry 11:352-360.
    • (2006) Mol Psychiatry , vol.11 , pp. 352-360
    • Lewis, S.J.1    Lawlor, D.A.2    Davey Smith, G.3    Araya, R.4    Timpson, N.5    Day, I.N.6    Ebrahim, S.7
  • 14
    • 84865822927 scopus 로고    scopus 로고
    • Pharmacogenetic aspects of antipsychotic drug-induced weight gain: A critical review
    • Reynolds GP (2012) Pharmacogenetic aspects of antipsychotic drug-induced weight gain: a critical review. Clin Psychopharmacol Neurosci 10:71-77.
    • (2012) Clin Psychopharmacol Neurosci , vol.10 , pp. 71-77
    • Reynolds, G.P.1
  • 15
    • 0037097014 scopus 로고    scopus 로고
    • Association of antipsychotic drug-induced weight gain with a 5-HT2C receptor gene polymorphism
    • Reynolds GP, Zhang ZJ, Zhang XB (2002) Association of antipsychotic drug-induced weight gain with a 5-HT2C receptor gene polymorphism. Lancet 359:2086-2087.
    • (2002) Lancet , vol.359 , pp. 2086-2087
    • Reynolds, G.P.1    Zhang, Z.J.2    Zhang, X.B.3
  • 16
    • 84878829550 scopus 로고    scopus 로고
    • The obesity risk gene FTO influences bodymass in chronic schizophrenia but not initial antipsychotic drug-induced weight gain in first-episode patients
    • Reynolds GP, Yevtushenko OO, Gordon S, Arranz B, San L, Cooper SJ (2013) The obesity risk gene FTO influences bodymass in chronic schizophrenia but not initial antipsychotic drug-induced weight gain in first-episode patients. Int J Neuropsychopharmacol 16:1421-1425.
    • (2013) Int J Neuropsychopharmacol , vol.16 , pp. 1421-1425
    • Reynolds, G.P.1    Yevtushenko, O.O.2    Gordon, S.3    Arranz, B.4    San, L.5    Cooper, S.J.6
  • 17
    • 0033846460 scopus 로고    scopus 로고
    • Genomic DNA hypomethylation, a characteristic of most cancers, is present in peripheral leukocytes of individuals who are homozygous for the C677T polymorphism in the methylenetetrahydrofolate reductase gene
    • Stern LL, Mason JB, Selhub J, Choi SW (2000) Genomic DNA hypomethylation, a characteristic of most cancers, is present in peripheral leukocytes of individuals who are homozygous for the C677T polymorphism in the methylenetetrahydrofolate reductase gene. Cancer Epidemiol Biomarkers Prev 9:849-853.
    • (2000) Cancer Epidemiol Biomarkers Prev , vol.9 , pp. 849-853
    • Stern, L.L.1    Mason, J.B.2    Selhub, J.3    Choi, S.W.4
  • 18
    • 33746845341 scopus 로고    scopus 로고
    • One-carbon metabolism in psychiatric illness
    • Sugden C (2006) One-carbon metabolism in psychiatric illness. Nutr Res Rev 19:117-136.
    • (2006) Nutr Res Rev , vol.19 , pp. 117-136
    • Sugden, C.1
  • 19
    • 17644394540 scopus 로고    scopus 로고
    • Polymorphisms of the 5-HT2C receptor and leptin genes are associated with antipsychotic drug-induced weight gain in Caucasian subjects with a first-episode psychosis
    • Templeman LA, Reynolds GP, Arranz B, San L (2005) Polymorphisms of the 5-HT2C receptor and leptin genes are associated with antipsychotic drug-induced weight gain in Caucasian subjects with a first-episode psychosis. Pharmacogenet Genomics 15:195-200.
    • (2005) Pharmacogenet Genomics , vol.15 , pp. 195-200
    • Templeman, L.A.1    Reynolds, G.P.2    Arranz, B.3    San, L.4
  • 23
    • 77955471578 scopus 로고    scopus 로고
    • MTHFR genotype and differential evolution of metabolic parameters after initiation of a second generation antipsychotic: An observational study
    • van Winkel R, Moons T, Peerbooms O, Rutten B, Peuskens J, Claes S, van Os J, De Hert M (2010b) MTHFR genotype and differential evolution of metabolic parameters after initiation of a second generation antipsychotic: an observational study. Int Clin Psychopharmacol 25:270-276.
    • (2010) Int Clin Psychopharmacol , vol.25 , pp. 270-276
    • Van Winkel, R.1    Moons, T.2    Peerbooms, O.3    Rutten, B.4    Peuskens, J.5    Claes, S.6    Van Os, J.7    De Hert, M.8
  • 24
    • 0031687887 scopus 로고    scopus 로고
    • A second genetic polymorphism in methylenetetrahydrofolate reductase (MTHFR) associated with decreased enzyme activity
    • Weisberg I, Tran P, Christensen B, Sibani S, Rozen R (1998) A second genetic polymorphism in methylenetetrahydrofolate reductase (MTHFR) associated with decreased enzyme activity. Mol Genet Metab 64:169-172.
    • (1998) Mol Genet Metab , vol.64 , pp. 169-172
    • Weisberg, I.1    Tran, P.2    Christensen, B.3    Sibani, S.4    Rozen, R.5
  • 25
    • 0346373688 scopus 로고    scopus 로고
    • Effects of antipsychotics on fat deposition and changes in leptin and insulin levels. Magnetic resonance imaging study of previously untreated people with schizophrenia
    • Zhang ZJ, Yao ZJ, Liu W, Fang Q, Reynolds GP (2004) Effects of antipsychotics on fat deposition and changes in leptin and insulin levels. Magnetic resonance imaging study of previously untreated people with schizophrenia. Br J Psychiatry 184:58-62.
    • (2004) Br J Psychiatry , vol.184 , pp. 58-62
    • Zhang, Z.J.1    Yao, Z.J.2    Liu, W.3    Fang, Q.4    Reynolds, G.P.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.