Proteome analysis of the anti-inflammatory response of flavonoids isolated from Korean Citrus aurantium L. in lipopolysaccharide-induced l6 rat skeletal muscle cells

American Journal of Chinese Medicine

Volumn 41, Issue 4, 2013, Pages 901-912

  Kim, Jin A ^a   Park, Hyeon Soo ^b   Park, Kwang Il ^b   Hong, Gyeong Eun ^b   Nagappan, Arulkumar ^b   Zhang, Jue ^c   Han, Dae Yong ^d   Shin, Sung Chul ^b   Won, Chung Gil ^b   Kim, Eun Hee ^e   Kim, Gon Sup ^b  

^a Korea National Animal Research Resource Center   (South Korea)

^b Gyeongsang National University   (South Korea)

^c JIANGSU INSTITUTE OF NUCLEAR MEDICINE   (China)

^d Daegu Gyeongbuk Medical Innovation Foundation   (South Korea)

^e International University of Korea   (South Korea)

Author keywords

Flavonoids; Korea Citrus aurantium L; L6 Skeletal Muscle Cell; Lipopolysaccharide (LPS); Matrix Assisted Laser Desorption Ionization Time of Flight Mass Spectroscopy (MALDI TOF MS)

Indexed keywords

FLAVONOID; LIPOPOLYSACCHARIDE;

ANIMAL EXPERIMENT; ANTIINFLAMMATORY ACTIVITY; ARTICLE; IMAGE ANALYSIS; ISOLATION AND PURIFICATION; MATRIX ASSISTED LASER DESORPTION IONIZATION TIME OF FLIGHT MASS SPECTROMETRY; MUSCLE CELL; NONHUMAN; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEOMICS; RAT; SKELETAL MUSCLE; SOUR ORANGE; TWO DIMENSIONAL ELECTROPHORESIS;

ANIMALS; ANTI-INFLAMMATORY AGENTS; CELL LINE; CITRUS; ELECTROPHORESIS; ENDOTOXINS; FLAVONOIDS; LIPOPOLYSACCHARIDES; MUSCLE FIBERS, SKELETAL; PROTEOME; RATS; SPECTROMETRY, MASS, MATRIX-ASSISTED LASER DESORPTION-IONIZATION;

EID: 84881156172     PISSN: 0192415X     EISSN: None     Source Type: Journal    
DOI: 10.1142/S0192415X13500602     Document Type: Article

References (24)

1. Al-Ashaal, H.A. and S.T. El-Sheltawy. Antioxidant capacity of hesperidin from citrus peel using electron spin resonance and cytotoxic activity against human carcinoma cell lines. Pharm. Biol. 49: 276-282, 2011.
2. Beutler, B., N. Krochin, I.W. Milsark, C. Luedke and A. Cerami. Control of cachectin (tumor necrosis factor) synthesis: mechanisms of endotoxin resistance. Science 232: 977-980, 1986. (Pubitemid 16085400)
3. Bicer, S., P.J. Reiser, S. Ching and N. Quan. Induction of muscle weakness by local inflammation: an experimental animal model. Inflamm. Res. 58: 175-183, 2009.
4. Bodet, C., V.D. La, F. Epifano and D. Grenier. Naringenin has anti-inflammatory properties in macrophage and ex vivo human whole-blood models. J. Periodontal Res. 43: 400-407, 2008.
5. Bommareddy, A., B. Rule, A.L. Vanwert, S. Santha and C. Dwivedi. Alpha-Santalol, a derivative of sandalwood oil, induces apoptosis in human prostate cancer cells by causing caspase-3 activation. Phytomedicine 19: 804-811, 2012.
6. Chen, K., G.W. Plumb, R.N. Bennett and Y. Bao. Antioxidant activities of extracts from five antiviral medicinal plants. J. Ethnopharmacol. 96: 201-205, 2005. (Pubitemid 39575052)
7. Chidambara Murthy, K.N., G.K. Jayaprakasha and B.S. Patil. Apoptosis mediated cytotoxicity of citrus obacunone in human pancreatic cancer cells. Toxicol. In Vitro 25: 859-867, 2011.
8. De Paepe, B., K.K. Creus and J.L. De Bleecker. Chemokine profile of different inflammatory myopathies reflects humoral versus cytotoxic immune responses. Ann. N. Y. Acad. Sci. 1109: 441-453, 2007. (Pubitemid 47511387)
9. Du, J., X. Wang, C. Miereles, J.L. Bailey, R. Debigare, B. Zheng, S.R. Price and W.E. Mitch. Activation of caspase-3 is an initial step triggering accelerated muscle proteolysis in catabolic conditions. J. Clin. Invest. 113: 115-123, 2004. (Pubitemid 38541638)
10. Grundtman, C., V. Malmstrom and I.E. Lundberg. Immune mechanisms in the pathogenesis of idiopathic inflammatory myopathies. Arthritis Res. Ther. 9: 208, 2007.
11. Hirota, R., N.N. Roger, H. Nakamura, H.S. Song, M. Sawamura and N. Suganuma. Antiinflammatory effects of limonene from yuzu (Citrus junos Tanaka) essential oil on eosinophils. J. Food Sci. 75: H87-92, 2010.
12. Jana, M., S. Dasgupta, R.N. Saha, X. Liu and K. Pahan. Induction of tumor necrosis factor-alpha (TNF-alpha) by interleukin-12 p40 monomer and homodimer in microglia and macrophages. J. Neurochem. 86: 519-528, 2003. (Pubitemid 36842451)
13. Kang, S.R., D.Y. Han, K.I. Park, H.S. Park, Y.B. Cho, H.J. Lee, W.S. Lee, C.H. Ryu, Y.L. Ha, H. Lee do, J.A. Kim and G.S. Kim. Suppressive effect on lipopolysaccharide-induced proinflammatory mediators by Citrus aurantium L. in macrophage raw 264.7 cells via NF-kappaB signal pathway. Evid. Based Complement. Alternat. Med. 2011: 248592, 2011.
14. Kang, K.A., R. Zhang, M.J. Piao, S. Chae, H.S. Kim, J.H. Park, K.S. Jung and J.W. Hyun. Baicalein inhibits oxidative stress-induced cellular damage via antioxidant effects. Toxicol. Ind. Health, 28: 412-421, 2012.
15. Kim, J.A., H.S. Park, S.R. Kang, K.I. Park, D.H. Lee, A. Nagappan, S.C. Shin, W.S. Lee, E.H. Kim and G.S. Kim. Suppressive effect of flavonoids from Korean Citrus aurantium L. on the expression of inflammatory mediators in l6 skeletal muscle cells. Phytother. Res. 26: 1904-1912, 2012.
16. Lee, D.H., K.I. Park, H.S. Park, S.R. Kang, A. Nagappan, J.A. Kim, E.H. Kim, W.S. Lee, Y.S. Hah, H.J. Chung, S.J. An and G.S. Kim. Flavonoids isolated from Korea Citrus aurantium L. induce G2/M phase arrest and apoptosis in human gastric cancer AGS cells. Evid. Based Complement. Alternat. Med. 2012: 515901, 2012.
17. McCarthy, F.M., N. Wang, G.B. Magee, B. Nanduri, M.L. Lawrence, E.B. Camon, D.G. Barrell, D.P. Hill, M.E. Dolan, W.P. Williams, D.S. Luthe, S.M. Bridges and S.C. Burgess. AgBase: a functional genomics resource for agriculture. BMC Genomics 7: 229, 2006.
18. Park, E., S. Kum, C. Wang, S.Y. Park, B.S. Kim and G. Schuller-Levis. Anti-inflammatory activity of herbal medicines: inhibition of nitric oxide production and tumor necrosis factor-alpha secretion in an activated macrophage-like cell line. Am. J. Chin. Med. 33: 415-424, 2005. (Pubitemid 40909139)
19. Park, H.S., K.I. Park, A. Nagappan, D.H. Lee, S.R. Kang, J.A. Kim, E.H. Kim, D.Y. Han and G.S. Kim. Proteomic analysis of effects on natural herb additive containing immunoglobulin Yolksac (IgY) in pigs. Am. J. Chin. Med. 39: 477-488, 2011.
20. Porter, A.G. and R.U. Janicke. Emerging roles of caspase-3 in apoptosis. Cell Death Differ. 6: 99-104, 1999. (Pubitemid 29082297)
21. Reshef, N., Y. Hayari, C. Goren, M. Boaz, Z. Madar and H. Knobler. Antihypertensive effect of sweetie fruit in patients with stage I hypertension. Am. J. Hypertens. 18: 1360-1363, 2005. (Pubitemid 41400208)
22. Rizza, S., R. Muniyappa, M. Iantorno, J.A. Kim, H. Chen, P. Pullikotil, N. Senese, M. Tesauro, D. Lauro, C. Cardillo and M.J. Quon. Citrus polyphenol hesperidin stimulates production of nitric oxide in endothelial cells while improving endothelial function and reducing inflammatory markers in patients with metabolic syndrome. J. Clin. Endocrinol. Metab. 96: E782-E792, 2011.
23. Shevchenko, A., M. Wilm, O. Vorm and M. Mann. Mass spectrometric sequencing of proteins silverstained polyacrylamide gels. Anal. Chem. 68: 850-858, 1996.
24. Vescovo, G. and L. Dalla Libera. Skeletal muscle apoptosis in experimental heart failure: the only link between inflammation and skeletal muscle wastage? Curr. Opin. Clin. Nutr. Metab. Care 9: 416-422, 2006. (Pubitemid 44097812)