Enhanced excitability of MRGPRA3-and MRGPRD-positive nociceptors in a model of inflammatory itch and pain

Brain

Volumn 137, Issue 4, 2014, Pages 1039-1050

  Qu, Lintao ^a   Fan, Ni ^a,b   Ma, Chao ^a,c   Wang, Tao ^a,c   Han, Liang ^d   Fu, Kai ^a   Wang, Yingdi ^a   Shimada, Steven G ^a   Dong, Xinzhong ^d   Lamotte, Robert H ^a  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b GUANGZHOU MEDICAL UNIVERSITY   (China)

^c INSTITUTE OF BASIC MEDICAL SCIENCES   (China)

^d JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

allergic contact dermatitis; itch; MRGPRA3; MRGPRD; pain

Indexed keywords

G PROTEIN COUPLED RECEPTOR; HAPTEN; MAS RELATED G PROTEIN COUPLED RECEPTOR MRGPRA3; SQUARIC ACID DIBUTYL ESTER; UNCLASSIFIED DRUG; MRGPRA3 PROTEIN, MOUSE; MRGPRD PROTEIN, MOUSE;

ACTION POTENTIAL; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BITE; CELL COUNT; CONTACT ALLERGY; CONTROLLED STUDY; CURRENT CLAMP TECHNIQUE; ELECTROPHYSIOLOGICAL PROCEDURES; FLUORESCENCE MICROSCOPY; HEAD MOVEMENT; IN VITRO STUDY; IN VIVO STUDY; INFLAMMATORY PAIN; LAMINECTOMY; MALE; MECHANICAL STIMULATION; MEMBRANE STEADY POTENTIAL; MOUSE; NERVE CELL EXCITABILITY; NERVE ENDING; NONHUMAN; PAIN RECEPTOR; PRIORITY JOURNAL; PRURITUS; RECEPTIVE FIELD; SCRATCHING; SKIN ALLERGY; SKIN SWELLING; SKINFOLD THICKNESS; SODIUM CURRENT; SPINAL GANGLION; STEADY STATE; WHOLE CELL PATCH CLAMP; ANIMAL; C57BL MOUSE; CONTACT DERMATITIS; DISEASE MODEL; INFLAMMATION; INNERVATION; METABOLISM; NERVE CELL; PAIN; PATCH CLAMP TECHNIQUE; PATHOPHYSIOLOGY; PHYSIOLOGY; SKIN; TRANSGENIC MOUSE;

ANIMALS; DERMATITIS, CONTACT; DISEASE MODELS, ANIMAL; GANGLIA, SPINAL; INFLAMMATION; MALE; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; NEURONS; NOCICEPTORS; PAIN; PATCH-CLAMP TECHNIQUES; PRURITUS; RECEPTORS, G-PROTEIN-COUPLED; SKIN;

EID: 84897866502     PISSN: 00068950     EISSN: 14602156     Source Type: Journal    
DOI: 10.1093/brain/awu007     Document Type: Article

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