Antarease-like Zn-metalloproteases are ubiquitous in the venom of different scorpion genera

Biochimica et Biophysica Acta - General Subjects

Volumn 1840, Issue 6, 2014, Pages 1738-1746

  Ortiz, Ernesto ^a   Rendón Anaya, Martha ^b   Rego, Solange Cristina ^c   Schwartz, Elisabeth Ferroni ^c   Possani, Lourival Domingos ^a  

^a INSTITUTO DE BIOTECNOLOGÍA   (Mexico)

^b DEPARTAMENTO DE FÍSICA   (Mexico)

^c INSTITUTO DE CIÊNCIAS BIOLÓGICAS   (Brazil)

Author keywords

Antarease; cDNA library; Pancreatitis; Scorpion; Zn metalloprotease

Indexed keywords

ADAM PROTEIN; COMPLEMENTARY DNA; METALLOPROTEINASE; PRIMER DNA; SCORPION VENOM; SECRETORY PROTEIN; ANTAREASE; UNCLASSIFIED DRUG;

ARTICLE; CATALYSIS; CONFORMATIONAL TRANSITION; DNA LIBRARY; GENE SEQUENCE; GEOGRAPHY; MOLECULAR CLONING; NONHUMAN; NUCLEOTIDE SEQUENCE; PHYLOGENY; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; SCORPION; SEQUENCE HOMOLOGY; TITYUS SERRULATUS; TITYUS TRIVITTATUS; CONTROLLED STUDY; ENZYME ANALYSIS; ENZYME CONFORMATION; ENZYME STRUCTURE; MOLECULAR DYNAMICS; MOLECULAR EVOLUTION; PHYLOGEOGRAPHY; POISONOUS SCORPION; PROTEIN FUNCTION; SEQUENCE ALIGNMENT; SEQUENCE ANALYSIS; STRUCTURE ANALYSIS; TITYUS FASCIOLATUS; TITYUS PACHYURUS;

ANTAREASE; CDNA LIBRARY; PANCREATITIS; SCORPION; ZN-METALLOPROTEASE;

AMINO ACID SEQUENCE; BASE SEQUENCE; METALLOPROTEASES; MODELS, MOLECULAR; MOLECULAR DYNAMICS SIMULATION; MOLECULAR SEQUENCE DATA; PHYLOGEOGRAPHY; SCORPION VENOMS;

EID: 84897845584     PISSN: 03044165     EISSN: 18728006     Source Type: Journal    
DOI: 10.1016/j.bbagen.2013.12.012     Document Type: Article

References (52)

1. L.D. Waterman, Some notes on scorpion poisoning in Trinidad, Trans. R. Soc. Trop. Med. Hyg. 31 (1938) 607-624.
2. C. Bartholomew, Acute scorpion pancreatitis in Trinidad, Br. Med. J. 1 (1970) 666-668.
3. T. Poon-King, I. Mohammed, R. Cox, E.V. Potter, N.M. Simon, A.C. Siegel, D.P. Earle, Recurrent epidemic nephritis in South Trinidad, N. Engl. J. Med. 277 (1963) 728-733.
4. R. Otero, E. Navio, F.A. Cespedes, M.J. Nunez, L. Lozano, E.R. Moscoso, C. Matallana, N.B. Arsuza, J. Garcia, D. Fernandez, J.H. Rodas, O.J. Rodriguez, J.E. Zuleta, J.P. Gomez, M. Saldarriaga, J.C. Quintana, V. Nunez, S. Cardenas, J. Barona, R. Valderrama, N. Paz, A. Diaz, O.L. Rodriguez, M.D. Martinez, R. Maturana, L.E. Beltran, M.B. Mesa, J. Paniagua, E. Florez, W.R. Lourenco, Scorpion envenoming in two regions of Colombia: clinical, epidemiological and therapeutic aspects, Trans. R. Soc. Trop. Med. Hyg. 98 (2004) 742-750. (Pubitemid 39345152)
5. P.L. Fletcher Jr., M.D. Fletcher, L.D. Possani, Characteristics of pancreatic exocrine secretion produced by venom from the Brazilian scorpion, Tityus serrulatus, Eur. J. Cell Biol. 58 (1992) 259-270.
6. J.C. Machado, J.F. da Silveira Filho, Indução de pancreatite hemorrágica aguda no cão por veneno escorpiônico de T. serrulatus, Mem. Inst. Butantan 40-41 (1977) 1-9.
7. G. Novaes, O.L. Catanzaro, W.T. Beraldo, L. Freire-Maia, Effect of purified scorpion toxin (tityustoxin) on the pancreatic secretion of the rat, Toxicon 20 (1982) 847-853. (Pubitemid 13197041)
8. L.D. Possani, B.M. Martin, M.D. Fletcher, P.L. Fletcher Jr., Discharge effect on pancreatic exocrine secretion produced by toxins purified from Tityus serrulatus scorpion venom, J. Biol. Chem. 266 (1991) 3178-3185. (Pubitemid 21909191)
9. G. D'Suze, C. Sevcik, M. Ramos, Presence of curarizing polypeptides and a pancreatitis-inducing fraction without muscarinic effects in the venom of the Venezuelan scorpion Tityus discrepans (Karsch), Toxicon 33 (1995) 333-345.
10. A. Borges, E. Trejo, A.M. Vargas, G. Cespedes, A. Hernandez, M.J. Alfonzo, Pancreatic toxicity in mice elicited by Tityus zulianus and Tityus discrepans scorpion venoms, Invest. Clin. 45 (2004) 269-276. (Pubitemid 39244152)
11. M. Gueron, R. Yaron, Cardiovascular manifestations of severe scorpion sting. Clinicopathologic correlations, Chest 57 (1970) 156-162.
12. S. Sofer, H. Shalev, Z. Weizman, E. Shahak, M. Gueron, Acute pancreatitis in children following envenomation by the yellow scorpion Leiurus quinquestriatus, Toxicon 29 (1991) 125-128.
13. K.R. Murthy, J.D. Medh, B.N. Dave, Y.E. Vakil, F.R. Billimoria, Acute pancreatitis and reduction of H + ion concentration in gastric secretions in experimental acute myocarditis produced by Indian red scorpion, Buthus tamulus, venom, Indian J. Exp. Biol. 27 (1989) 242-244.
14. M.D. Fletcher, L.D. Possani, P.L. Fletcher Jr., Morphological studies by light and electron microscopy of pancreatic acinar cells under the effect of Tityus serrulatus venom, Cell Tissue Res. 278 (1994) 255-264. (Pubitemid 24315097)
15. P.L. Fletcher, M. Fletcher, L.K. Fainter, D.M. Terrian, Action of New World scorpion venom and its neurotoxins in secretion, Toxicon 34 (1996) 1399-1411. (Pubitemid 27051465)
16. M.V. Gomez, C.R. Diniz, Separation of toxic components from the Brazillian scorpion Tityus serrulatus venom, Mem. Inst. Butantan 33 (1966) 899-902.
17. E.C. Arantes, S.V. Sampaio, C.A. Vieira, J.R. Giglio, What is tityustoxin? Toxicon 30 (1992) 786-789.
18. A.P. Corrado, A. Antonio, C.R. Diniz, Brazilian scorpion venom (Tityus serrulatus), an unusual sympathetic postganglionic stimulant, J. Pharmacol. Exp. Ther. 164 (1968) 253-258.
19. L. Freire-Maia, M.C. Ferreira, Estudo do mecanismo da hiperglicemia e da hipertensão arterial, produzidas pelo veneno de escorpião, no cão, Mem. Inst. Oswaldo Cruz 59 (1961) 11-22.
20. S.A. Ibrahim, Phospholipase A in scorpion venoms, Toxicon 5 (1967) 59-60.
21. N.A. Valdez-Cruz, C.V. Batista, L.D. Possani, Phaiodactylipin, a glycosylated heterodimeric phospholipase A from the venom of the scorpion Anuroctonus phaiodactylus, Eur. J. Biochem. 271 (2004) 1453-1464. (Pubitemid 38553551)
22. R.B. Nair, P.A. Kurup, Investigations on the venom of the South Indian scorpion Heterometrus scaber, Biochim. Biophys. Acta 381 (1975) 165-174.
23. L. Borchani, A. Sassi, D. Shahbazzadeh, J.M. Strub, H. Tounsi-Guetteti, M.S. Boubaker, A. Akbari, A. Van Dorsselaer, M. El Ayeb, Heminecrolysin, the first hemolytic dermonecrotic toxin purified from scorpion venom, Toxicon 58 (2011) 130-139.
24. C.V. Batista, S.A. Roman-Gonzalez, S.P. Salas-Castillo, F.Z. Zamudio, F. Gomez-Lagunas, L.D. Possani, Proteomic analysis of the venom from the scorpion Tityus stigmurus: biochemical and physiological comparison with other Tityus species, Comp. Biochem. Physiol. C Toxicol. Pharmacol. 146 (2007) 147-157. (Pubitemid 47071783)
25. F.M. Almeida, A.M. Pimenta, S.G. De Figueiredo, M.M. Santoro, M.F. Martin-Eauclaire, C.R. Diniz, M.E. De Lima, Enzymes with gelatinolytic activity can be found in Tityus bahiensis and Tityus serrulatus venoms, Toxicon 40 (2002) 1041-1045. (Pubitemid 34663697)
26. M.F. Martin-Eauclaire, B. Ceard, A.M. Ribeiro, C.R. Diniz, H. Rochat, P.E. Bougis, Biochemical, pharmacological and genomic characterisation of Ts IV, an alpha-toxin from the venom of the South American scorpion Tityus serrulatus, FEBS Lett. 342 (1994) 181-184. (Pubitemid 24115192)
27. P.L. Fletcher Jr., M.D. Fletcher, K. Weninger, T.E. Anderson, B.M. Martin, Vesicle-associated membrane protein (VAMP) cleavage by a new metalloprotease from the Brazilian scorpion Tityus serrulatus, J. Biol. Chem. 285 (2010) 7405-7416.
28. I. Amaro, L. Riano-Umbarila, B. Becerril, L.D. Possani, Isolation and characterization of a human antibody fragment specific for Ts1 toxin from Tityus serrulatus scorpion, Immunol. Lett. 139 (2011) 73-79.
29. L. Riano-Umbarila, G. Contreras-Ferrat, T. Olamendi-Portugal, C. Morelos-Juarez, G. Corzo, L.D. Possani, B. Becerril, Exploiting cross-reactivity to neutralize two different scorpion venoms with one single chain antibody fragment, J. Biol. Chem. 286 (2011) 6143-6151.
30. E.J. Venancio, F.C. Portaro, A.K. Kuniyoshi, D.C. Carvalho, G. Pidde-Queiroz, D.V. Tambourgi, Enzymatic properties of venoms from Brazilian scorpions of Tityus genus and the neutralisation potential of therapeutical antivenoms, Toxicon 69 (2013) 180-190.
31. E. Diego-Garcia, E.F. Schwartz, G. D'Suze, S.A. Gonzalez, C.V. Batista, B.I. Garcia, R.C. de la Vega, L.D. Possani, Wide phylogenetic distribution of scorpine and long-chain beta-KTx-like peptides in scorpion venoms: identification of "orphan" components, Peptides 28 (2007) 31-37. (Pubitemid 44959184)
32. S.F. Altschul, W. Gish, W. Miller, E.W. Myers, D.J. Lipman, Basic local alignment search tool, J. Mol. Biol. 215 (1990) 403-410.
33. L.A. Kelley, M.J. Sternberg, Protein structure prediction on the web: a case study using the Phyre server, Nat. Protoc. 4 (2009) 363-371.
34. S.F. Altschul, T.L. Madden, A.A. Schaffer, J. Zhang, Z. Zhang, W. Miller, D.J. Lipman, Gapped BLAST and PSI-BLAST: a new generation of protein database search programs, Nucleic Acids Res. 25 (1997) 3389-3402. (Pubitemid 27359211)
35. J. Soding, Protein homology detection by HMM-HMM comparison, Bioinformatics 21 (2005) 951-960. (Pubitemid 40467915)
36. B.R. Brooks, C.L. Brooks III, A.D. Mackerell Jr., L. Nilsson, R.J. Petrella, B. Roux, Y. Won, G. Archontis, C. Bartels, S. Boresch, A. Caflisch, L. Caves, Q. Cui, A.R. Dinner, M. Feig, S. Fischer, J. Gao, M. Hodoscek, W. Im, K. Kuczera, T. Lazaridis, J. Ma, V. Ovchinnikov, E. Paci, R.W. Pastor, C.B. Post, J.Z. Pu, M. Schaefer, B. Tidor, R.M. Venable, H.L. Woodcock, X. Wu, W. Yang, D.M. York, M. Karplus, CHARMM: the biomolecular simulation program, J. Comput. Chem. 30 (2009) 1545-1614.
37. J.C. Phillips, R. Braun, W. Wang, J. Gumbart, E. Tajkhorshid, E. Villa, C. Chipot, R.D. Skeel, L. Kale, K. Schulten, Scalable molecular dynamics with NAMD, J. Comput. Chem. 26 (2005) 1781-1802. (Pubitemid 43078511)
38. T. Darden, D. York, L. Pedersen, Particle mesh Ewald - an N.log(N) method for Ewald sums in large systems, J. Chem. Phys. 98 (1993) 10089-10092.
39. J.P. Ryckaert, G. Ciccotti, H.J.C. Berendsen, Numerical-integration of Cartesian equations of motion of a system with constraints - molecular-dynamics of N-alkanes, J. Comput. Phys. 23 (1977) 327-341.
40. W. Humphrey, A. Dalke, K. Schulten, VMD: visual molecular dynamics, J. Mol. Graph. 14 (33-38) (1996) 27-38.
41. M. Rendon-Anaya, L. Delaye, L.D. Possani, A. Herrera-Estrella, Global transcriptome analysis of the scorpion Centruroides noxius: new toxin families and evolutionary insights from an ancestral scorpion species, PLoS One 7 (2012) e43331.
42. G. Talavera, J. Castresana, Improvement of phylogenies after removing divergent and ambiguously aligned blocks from protein sequence alignments, Syst. Biol. 56 (2007) 564-577. (Pubitemid 47171631)
43. K. Tamura, D. Peterson, N. Peterson, G. Stecher, M. Nei, S. Kumar, MEGA5: molecular evolutionary genetics analysis using maximum likelihood, evolutionary distance, and maximum parsimony methods, Mol. Biol. Evol. 28 (2011) 2731-2739.
44. T.G. Wolfsberg, P. Primakoff, D.G. Myles, J.M. White, ADAM, a novel family of membrane proteins containing A disintegrin and metalloprotease domain: multipotential functions in cell-cell and cell-matrix interactions, J. Cell Biol. 131 (1995) 275-278.
45. P. Primakoff, D.G. Myles, The ADAM gene family: surface proteins with adhesion and protease activity, Trends Genet. 16 (2000) 83-87. (Pubitemid 30084721)
46. N.D. Rawlings, A.J. Barrett, Evolutionary families of metallopeptidases, Methods Enzymol. 248 (1995) 183-228.
47. N.M. Hooper, Families of zinc metalloproteases, FEBS Lett. 354 (1994) 1-6. (Pubitemid 24331694)
48. W. Bode, F.X. Gomis-Ruth, W. Stockler, Astacins, serralysins, snake venom and matrix metalloproteinases exhibit identical zinc-binding environments (HEXXHXXGXXH and Met-turn) and topologies and should be grouped into a common family, the 'metzincins', FEBS Lett. 331 (1993) 134-140. (Pubitemid 23285641)
49. H.H. Guan, K.S. Goh, F. Davamani, P.L. Wu, Y.W. Huang, J. Jeyakanthan, W.G. Wu, C.J. Chen, Structures of two elapid snake venom metalloproteases with distinct activities highlight the disulfide patterns in the D domain of ADAMalysin family proteins, J. Struct. Biol. 169 (2010) 294-303.
50. N.D. Rawlings, A.J. Barrett, A. Bateman, MEROPS: the database of proteolytic enzymes, their substrates and inhibitors, Nucleic Acids Res. 40 (2012) D343-D350.
51. J.A. Guerrero-Vargas, C.B. Mourao, V. Quintero-Hernandez, L.D. Possani, E.F. Schwartz, Identification and phylogenetic analysis of Tityus pachyurus and Tityus obscurus novel putative Na+-channel scorpion toxins, PLoS One 7 (2012) e30478.
52. G.P. Espino-Solis, L. Riano-Umbarila, B. Becerril, L.D. Possani, Antidotes against venomous animals: state of the art and prospectives, J. Proteomics 72 (2009) 183-199.