-
1
-
-
84863207933
-
Reduced insulin exocytosis in human pancreatic β-cells with gene variants linked to type 2 diabetes
-
Rosengren AH, Braun M, Mahdi T, et al. Reduced insulin exocytosis in human pancreatic β-cells with gene variants linked to type 2 diabetes. Diabetes 2012;61:1726-1733
-
(2012)
Diabetes
, vol.61
, pp. 1726-1733
-
-
Rosengren, A.H.1
Braun, M.2
Mahdi, T.3
-
2
-
-
34248512934
-
Clinical aspects of type-1 long-QT syndrome by location, coding type, and biophysical function of mutations involving the KCNQ1 gene
-
Moss AJ, Shimizu W, Wilde AA, et al. Clinical aspects of type-1 long-QT syndrome by location, coding type, and biophysical function of mutations involving the KCNQ1 gene. Circulation 2007;115:2481-2489
-
(2007)
Circulation
, vol.115
, pp. 2481-2489
-
-
Moss, A.J.1
Shimizu, W.2
Wilde, A.A.3
-
3
-
-
70449435450
-
The genetic basis of long QT and short QT syndromes: A mutation update
-
Hedley PL, Jørgensen P, Schlamowitz S, et al. The genetic basis of long QT and short QT syndromes: a mutation update. Hum Mutat 2009;30:1486-1511
-
(2009)
Hum Mutat
, vol.30
, pp. 1486-1511
-
-
Hedley, P.L.1
Jørgensen, P.2
Schlamowitz, S.3
-
4
-
-
50449085998
-
Variants in KCNQ1 are associated with susceptibility to type 2 diabetes mellitus
-
Yasuda K, Miyake K, Horikawa Y, et al. Variants in KCNQ1 are associated with susceptibility to type 2 diabetes mellitus. Nat Genet 2008;40:1092-1097
-
(2008)
Nat Genet
, vol.40
, pp. 1092-1097
-
-
Yasuda, K.1
Miyake, K.2
Horikawa, Y.3
-
5
-
-
50449085212
-
SNPs in KCNQ1 are associated with susceptibility to type 2 diabetes in East Asian and European populations
-
Unoki H, Takahashi A, Kawaguchi T, et al. SNPs in KCNQ1 are associated with susceptibility to type 2 diabetes in East Asian and European populations. Nat Genet 2008;40:1098-1102
-
(2008)
Nat Genet
, vol.40
, pp. 1098-1102
-
-
Unoki, H.1
Takahashi, A.2
Kawaguchi, T.3
-
6
-
-
67649974089
-
The type 2 diabetes associated minor allele of rs2237895 KCNQ1 associates with reduced insulin release following an oral glucose load
-
Holmkvist J, Banasik K, Andersen G, et al. The type 2 diabetes associated minor allele of rs2237895 KCNQ1 associates with reduced insulin release following an oral glucose load. PLoS ONE 2009;4:e5872
-
(2009)
PLoS ONE
, vol.4
-
-
Holmkvist, J.1
Banasik, K.2
Andersen, G.3
-
7
-
-
70349640785
-
A variant in the KCNQ1 gene predicts future type 2 diabetes and mediates impaired insulin secretion
-
Jonsson A, Isomaa B, Tuomi T, et al. A variant in the KCNQ1 gene predicts future type 2 diabetes and mediates impaired insulin secretion. Diabetes 2009;58:2409-2413
-
(2009)
Diabetes
, vol.58
, pp. 2409-2413
-
-
Jonsson, A.1
Isomaa, B.2
Tuomi, T.3
-
8
-
-
28344448471
-
Effects of I(Ks) channel inhibitors in insulin-secreting INS-1 cells
-
Ullrich S, Su J, Ranta F, et al. Effects of I(Ks) channel inhibitors in insulin-secreting INS-1 cells. Pflugers Arch 2005;451:428-436
-
(2005)
Pflugers Arch
, vol.451
, pp. 428-436
-
-
Ullrich, S.1
Su, J.2
Ranta, F.3
-
9
-
-
79954619559
-
Voltage-gated K+ channel KCNQ1 regulates insulin secretion in MIN6 β-cell line
-
Yamagata K, Senokuchi T, Lu M, et al. Voltage-gated K+ channel KCNQ1 regulates insulin secretion in MIN6 β-cell line. Biochem Biophys Res Commun 2011;407:620-625
-
(2011)
Biochem Biophys Res Commun
, vol.407
, pp. 620-625
-
-
Yamagata, K.1
Senokuchi, T.2
Lu, M.3
-
11
-
-
0346394178
-
A randomized non-pharmacological intervention study for prevention of ischaemic heart disease: Baseline results Inter99
-
Jørgensen T, Borch-Johnsen K, Thomsen TF, Ibsen H, Glümer C, Pisinger C. A randomized non-pharmacological intervention study for prevention of ischaemic heart disease: baseline results Inter99. Eur J Cardiovasc Prev Rehabil 2003;10:377-386
-
(2003)
Eur J Cardiovasc Prev Rehabil
, vol.10
, pp. 377-386
-
-
Jørgensen, T.1
Borch-Johnsen, K.2
Thomsen, T.F.3
Ibsen, H.4
Glümer, C.5
Pisinger, C.6
-
12
-
-
80054713602
-
GIANT Consortium. Homozygous carriers of the G allele of rs4664447 of the glucagon gene (GCG) are characterised by decreased fasting and stimulated levels of insulin, glucagon and glucagon-like peptide (GLP)-1
-
Torekov SS, Ma L, Grarup N, et al.; GIANT Consortium. Homozygous carriers of the G allele of rs4664447 of the glucagon gene (GCG) are characterised by decreased fasting and stimulated levels of insulin, glucagon and glucagon-like peptide (GLP)-1. Diabetologia 2011;54:2820-2831
-
(2011)
Diabetologia
, vol.54
, pp. 2820-2831
-
-
Torekov, S.S.1
Ma, L.2
Grarup, N.3
-
13
-
-
84881139246
-
Cohort Profile: The Health2006 cohort, Research Centre for Prevention and Health
-
Thuesen BH, Cerqueira C, Aadahl M, et al. Cohort Profile: The Health2006 cohort, Research Centre for Prevention and Health. Int J Epidemiol 2013
-
(2013)
Int J Epidemiol
-
-
Thuesen, B.H.1
Cerqueira, C.2
Aadahl, M.3
-
14
-
-
33646769244
-
High-efficiency multiplex capillary electrophoresis single strand conformation polymorphism (multi-CE-SSCP) mutation screening of SCN5A: A rapid genetic approach to cardiac arrhythmia
-
Hofman-Bang J, Behr ER, Hedley P, et al. High-efficiency multiplex capillary electrophoresis single strand conformation polymorphism (multi-CE-SSCP) mutation screening of SCN5A: a rapid genetic approach to cardiac arrhythmia. Clin Genet 2006;69:504-511
-
(2006)
Clin Genet
, vol.69
, pp. 504-511
-
-
Hofman-Bang, J.1
Behr, E.R.2
Hedley, P.3
-
16
-
-
0032966760
-
A single strand conformation polymorphism/heteroduplex (SSCP/HD) method for detection of mutations in 15 exons of the KVLQT1 gene, associated with long QT syndrome
-
Larsen LA, Andersen PS, Kanters JK, Jacobsen JR, Vuust J, Christiansen M. A single strand conformation polymorphism/heteroduplex (SSCP/HD) method for detection of mutations in 15 exons of the KVLQT1 gene, associated with long QT syndrome. Clin Chim Acta 1999;280:113-125
-
(1999)
Clin Chim Acta
, vol.280
, pp. 113-125
-
-
Larsen, L.A.1
Andersen, P.S.2
Kanters, J.K.3
Jacobsen, J.R.4
Vuust, J.5
Christiansen, M.6
-
17
-
-
0034875039
-
A spectrum of functional effects for disease causing mutations in the Jervell and Lange-Nielsen syndrome
-
Huang L, Bitner-Glindzicz M, Tranebjaerg L, Tinker A. A spectrum of functional effects for disease causing mutations in the Jervell and Lange-Nielsen syndrome. Cardiovasc Res 2001;51:670-680
-
(2001)
Cardiovasc Res
, vol.51
, pp. 670-680
-
-
Huang, L.1
Bitner-Glindzicz, M.2
Tranebjaerg, L.3
Tinker, A.4
-
18
-
-
0027399450
-
Frequency and symptoms of hypoglycaemia experienced by patients with type 2 diabetes treated with insulin
-
Hepburn DA, MacLeod KM, Pell AC, Scougal IJ, Frier BM. Frequency and symptoms of hypoglycaemia experienced by patients with type 2 diabetes treated with insulin. Diabet Med 1993;10:231-237
-
(1993)
Diabet Med
, vol.10
, pp. 231-237
-
-
Hepburn, D.A.1
MacLeod, K.M.2
Pell, A.C.3
Scougal, I.J.4
Frier, B.M.5
-
19
-
-
0020585333
-
Molecular heterogeneity of glucagon in normal subjects and in patients with glucagon-producing tumours
-
Holst JJ. Molecular heterogeneity of glucagon in normal subjects and in patients with glucagon-producing tumours. Diabetologia 1983;24:359-365
-
(1983)
Diabetologia
, vol.24
, pp. 359-365
-
-
Holst, J.J.1
-
20
-
-
0028281773
-
Tissue and plasma concentrations of amidated and glycine-extended glucagon-like peptide I in humans
-
Orskov C, Rabenhøj L, Wettergren A, Kofod H, Holst JJ. Tissue and plasma concentrations of amidated and glycine-extended glucagon-like peptide I in humans. Diabetes 1994;43:535-539
-
(1994)
Diabetes
, vol.43
, pp. 535-539
-
-
Orskov, C.1
Rabenhøj, L.2
Wettergren, A.3
Kofod, H.4
Holst, J.J.5
-
21
-
-
79961244091
-
Incretin hormone and insulin responses to oral versus intravenous lipid administration in humans
-
Lindgren O, Carr RD, Deacon CF, et al. Incretin hormone and insulin responses to oral versus intravenous lipid administration in humans. J Clin Endocrinol Metab 2011;96:2519-2524
-
(2011)
J Clin Endocrinol Metab
, vol.96
, pp. 2519-2524
-
-
Lindgren, O.1
Carr, R.D.2
Deacon, C.F.3
-
22
-
-
0032430986
-
Power and sample size calculations for studies involving linear regression
-
Dupont WD, Plummer WD Jr. Power and sample size calculations for studies involving linear regression. Control Clin Trials 1998;19:589-601
-
(1998)
Control Clin Trials
, vol.19
, pp. 589-601
-
-
Dupont, W.D.1
Plummer Jr., W.D.2
-
23
-
-
0025215247
-
Power and sample size calculations. A review and computer program
-
Dupont WD, Plummer WD Jr. Power and sample size calculations. A review and computer program. Control Clin Trials 1990;11:116-128
-
(1990)
Control Clin Trials
, vol.11
, pp. 116-128
-
-
Dupont, W.D.1
Plummer Jr., W.D.2
-
24
-
-
21344451632
-
Evidence of an association between the Arg72 allele of the peptide YY and increased risk of type 2 diabetes
-
Torekov SS, Larsen LH, Glümer C, et al. Evidence of an association between the Arg72 allele of the peptide YY and increased risk of type 2 diabetes. Diabetes 2005;54:2261-2265
-
(2005)
Diabetes
, vol.54
, pp. 2261-2265
-
-
Torekov, S.S.1
Larsen, L.H.2
Glümer, C.3
-
25
-
-
0032821965
-
Insulin sensitivity indices obtained from oral glucose tolerance testing: Comparison with the euglycemic insulin clamp
-
Matsuda M, DeFronzo RA. Insulin sensitivity indices obtained from oral glucose tolerance testing: comparison with the euglycemic insulin clamp. Diabetes Care 1999;22:1462-1470
-
(1999)
Diabetes Care
, vol.22
, pp. 1462-1470
-
-
Matsuda, M.1
DeFronzo, R.A.2
-
26
-
-
78149428043
-
Insulin sensitivity is reflected by characteristic metabolic fingerprints - A Fourier transform mass spectrometric non-targeted metabolomics approach
-
Lucio M, Fekete A, Weigert C, et al. Insulin sensitivity is reflected by characteristic metabolic fingerprints - a Fourier transform mass spectrometric non-targeted metabolomics approach. PLoS ONE 2010;5:e13317
-
(2010)
PLoS ONE
, vol.5
-
-
Lucio, M.1
Fekete, A.2
Weigert, C.3
-
27
-
-
0031596399
-
Measuring pre-hepatic insulin secretion using a population model of C-peptide kinetics: Accuracy and required sampling schedule
-
Hovorka R, Koukkou E, Southerden D, Powrie JK, Young MA. Measuring pre-hepatic insulin secretion using a population model of C-peptide kinetics: accuracy and required sampling schedule. Diabetologia 1998;41:548-554
-
(1998)
Diabetologia
, vol.41
, pp. 548-554
-
-
Hovorka, R.1
Koukkou, E.2
Southerden, D.3
Powrie, J.K.4
Young, M.A.5
-
29
-
-
0037312821
-
The influence of GLP-1 on glucose-stimulated insulin secretion: Effects on beta-cell sensitivity in type 2 and nondiabetic subjects
-
Kjems LL, Holst JJ, Vølund A, Madsbad S. The influence of GLP-1 on glucose-stimulated insulin secretion: effects on beta-cell sensitivity in type 2 and nondiabetic subjects. Diabetes 2003;52:380-386
-
(2003)
Diabetes
, vol.52
, pp. 380-386
-
-
Kjems, L.L.1
Holst, J.J.2
Vølund, A.3
Madsbad, S.4
-
30
-
-
2542610014
-
A novel syndrome of autosomal-dominant hyperinsulinemic hypoglycemia linked to a mutation in the human insulin receptor gene
-
Højlund K, Hansen T, Lajer M, et al. A novel syndrome of autosomal-dominant hyperinsulinemic hypoglycemia linked to a mutation in the human insulin receptor gene. Diabetes 2004;53:1592-1598
-
(2004)
Diabetes
, vol.53
, pp. 1592-1598
-
-
Højlund, K.1
Hansen, T.2
Lajer, M.3
-
32
-
-
77956952342
-
Hormonal and pharmacological modification of plasma potassium homeostasis
-
Clausen T. Hormonal and pharmacological modification of plasma potassium homeostasis. Fundam Clin Pharmacol 2010;24:595-605
-
(2010)
Fundam Clin Pharmacol
, vol.24
, pp. 595-605
-
-
Clausen, T.1
-
33
-
-
29144482537
-
KCNQ1-dependent transport in renal and gastrointestinal epithelia
-
Vallon V, Grahammer F, Volkl H, et al. KCNQ1-dependent transport in renal and gastrointestinal epithelia. Proc Natl Acad Sci USA 2005;102:17864-17869
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, pp. 17864-17869
-
-
Vallon, V.1
Grahammer, F.2
Volkl, H.3
-
34
-
-
0038659995
-
Mechanisms of abnormal cardiac repolarization during insulin-induced hypoglycemia
-
Robinson RT, Harris ND, Ireland RH, Lee S, Newman C, Heller SR. Mechanisms of abnormal cardiac repolarization during insulin-induced hypoglycemia. Diabetes 2003;52:1469-1474
-
(2003)
Diabetes
, vol.52
, pp. 1469-1474
-
-
Robinson, R.T.1
Harris, N.D.2
Ireland, R.H.3
Lee, S.4
Newman, C.5
Heller, S.R.6
-
35
-
-
84891528921
-
Severe hypoglycemia-induced lethal cardiac arrhythmias are mediated by sympathoadrenal activation
-
Reno CM, Daphna-Iken D, Chen YS, VanderWeele J, Jethi K, Fisher SJ. Severe hypoglycemia-induced lethal cardiac arrhythmias are mediated by sympathoadrenal activation. Diabetes 2013;62:3570-3581
-
(2013)
Diabetes
, vol.62
, pp. 3570-3581
-
-
Reno, C.M.1
Daphna-Iken, D.2
Chen, Y.S.3
VanderWeele, J.4
Jethi, K.5
Fisher, S.J.6
-
36
-
-
70349208609
-
Extracellular K+ concentration controls cell surface density of IKr in rabbit hearts and of the HERG channel in human cell lines
-
Guo J, Massaeli H, Xu J, et al. Extracellular K+ concentration controls cell surface density of IKr in rabbit hearts and of the HERG channel in human cell lines. J Clin Invest 2009;119:2745-2757
-
(2009)
J Clin Invest
, vol.119
, pp. 2745-2757
-
-
Guo, J.1
Massaeli, H.2
Xu, J.3
-
37
-
-
75149149987
-
Serum glucose and insulin are associated with QTc and RR intervals in nondiabetic elderly
-
van NC
-
van Noord C, Sturkenboom MC, Straus SM, et al.; van NC. Serum glucose and insulin are associated with QTc and RR intervals in nondiabetic elderly. Eur J Endocrinol 2010;162:241-248
-
(2010)
Eur J Endocrinol
, vol.162
, pp. 241-248
-
-
Van Noord, C.1
Sturkenboom, M.C.2
Straus, S.M.3
-
38
-
-
84892397775
-
Vital signs, QT prolongation, and newly diagnosed cardiovascular disease during severe hypoglycemia in type 1 and type 2 diabetic patients
-
Tsujimoto T, Yamamoto-Honda R, Kajio H, et al. Vital signs, QT prolongation, and newly diagnosed cardiovascular disease during severe hypoglycemia in type 1 and type 2 diabetic patients. Diabetes Care 2014;37:217-225
-
(2014)
Diabetes Care
, vol.37
, pp. 217-225
-
-
Tsujimoto, T.1
Yamamoto-Honda, R.2
Kajio, H.3
-
39
-
-
0042879894
-
Voltage-dependent K(+) channels in pancreatic beta cells: Role, regulation and potential as therapeutic targets
-
MacDonald PE, Wheeler MB. Voltage-dependent K(+) channels in pancreatic beta cells: role, regulation and potential as therapeutic targets. Diabetologia 2003;46:1046-1062
-
(2003)
Diabetologia
, vol.46
, pp. 1046-1062
-
-
MacDonald, P.E.1
Wheeler, M.B.2
-
41
-
-
40749137051
-
Attenuation of counterregulatory responses to recurrent hypoglycemia by active thalamic inhibition: A mechanism for hypoglycemia-associated autonomic failure
-
Arbelaez AM, Powers WJ, Videen TO, Price JL, Cryer PE. Attenuation of counterregulatory responses to recurrent hypoglycemia by active thalamic inhibition: a mechanism for hypoglycemia-associated autonomic failure. Diabetes 2008;57:470-475
-
(2008)
Diabetes
, vol.57
, pp. 470-475
-
-
Arbelaez, A.M.1
Powers, W.J.2
Videen, T.O.3
Price, J.L.4
Cryer, P.E.5
-
42
-
-
78049300087
-
Insulin reciprocally regulates glucagon secretion in humans
-
Cooperberg BA, Cryer PE. Insulin reciprocally regulates glucagon secretion in humans. Diabetes 2010;59:2936-2940
-
(2010)
Diabetes
, vol.59
, pp. 2936-2940
-
-
Cooperberg, B.A.1
Cryer, P.E.2
-
43
-
-
9444266572
-
ATP-sensitive K+ channel-dependent regulation of glucagon release and electrical activity by glucose in wild-type and SUR1-/- mouse alpha-cells
-
Gromada J, Ma X, Høy M, et al. ATP-sensitive K+ channel-dependent regulation of glucagon release and electrical activity by glucose in wild-type and SUR1-/- mouse alpha-cells. Diabetes 2004;53(Suppl. 3):S181-S189
-
(2004)
Diabetes
, vol.53
, Issue.SUPPL. 3
-
-
Gromada, J.1
Ma, X.2
Høy, M.3
-
44
-
-
67650251656
-
Association of type 2 diabetes candidate polymorphisms in KCNQ1 with incretin and insulin secretion
-
Müssig K, Staiger H, Machicao F, et al. Association of type 2 diabetes candidate polymorphisms in KCNQ1 with incretin and insulin secretion. Diabetes 2009;58:1715-1720
-
(2009)
Diabetes
, vol.58
, pp. 1715-1720
-
-
Müssig, K.1
Staiger, H.2
Machicao, F.3
-
45
-
-
79951979514
-
Electrical activity-triggered glucagon-like peptide-1 secretion from primary murine L-cells
-
Rogers GJ, Tolhurst G, Ramzan A, et al. Electrical activity-triggered glucagon-like peptide-1 secretion from primary murine L-cells. J Physiol 2011;589:1081-1093
-
(2011)
J Physiol
, vol.589
, pp. 1081-1093
-
-
Rogers, G.J.1
Tolhurst, G.2
Ramzan, A.3
-
46
-
-
84860588948
-
Diabetes-associated common genetic variation and its association with GLP-1 concentrations and response to exogenous GLP-1
-
Smushkin G, Sathananthan M, Sathananthan A, et al. Diabetes-associated common genetic variation and its association with GLP-1 concentrations and response to exogenous GLP-1. Diabetes 2012;61:1082-1089
-
(2012)
Diabetes
, vol.61
, pp. 1082-1089
-
-
Smushkin, G.1
Sathananthan, M.2
Sathananthan, A.3
-
47
-
-
0029898525
-
No effect of beta-adrenergic blockade on hypoglycaemic effect of glucagon-like peptide-1 (GLP-1) in normal subjects
-
Toft-Nielsen M, Hvidberg A, Hilsted J, Dige-Petersen H, Holst JJ. No effect of beta-adrenergic blockade on hypoglycaemic effect of glucagon-like peptide-1 (GLP-1) in normal subjects. Diabet Med 1996;13:544-548
-
(1996)
Diabet Med
, vol.13
, pp. 544-548
-
-
Toft-Nielsen, M.1
Hvidberg, A.2
Hilsted, J.3
Dige-Petersen, H.4
Holst, J.J.5
|