Acute and chronic sectioning of fifth lumbar spinal nerve has equivalent effects on the primary afferents of sciatic nerve in rat spinal cord

Journal of Comparative Neurology

Volumn 517, Issue 4, 2009, Pages 481-492

  Shehab, Safa Aldeen S ^a  

^a UNITED ARAB EMIRATES UNIVERSITY   (United Arab Emirates)

Author keywords

Axotomy; Cholera toxin B subunit; IB4; Spinal cord; Sprouting; WGA HRP

Indexed keywords

ISOLECTIN B4;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL LABELING; CELL POPULATION; CELLULAR DISTRIBUTION; CONTROLLED STUDY; DENERVATION; MYELINATED NERVE; NERVE ENDING; NERVE INJURY; NERVE LIGATION; NERVE STIMULATION; NEUROPATHIC PAIN; NONHUMAN; PRIORITY JOURNAL; RAT; SCIATIC NERVE; SPINAL CORD DORSAL HORN; SPINAL NERVE;

ANIMALS; CHOLERA TOXIN; GANGLIA, SPINAL; GLYCOPROTEINS; LECTINS; LIGATION; LUMBOSACRAL REGION; NEURONS, AFFERENT; PERIPHERAL NERVOUS SYSTEM DISEASES; RATS; RATS, WISTAR; SCIATIC NERVE; SPINAL CORD; TIME FACTORS; WHEAT GERM AGGLUTININ-HORSERADISH PEROXIDASE CONJUGATE;

EID: 70350133700     PISSN: 00219967     EISSN: 10969861     Source Type: Journal    
DOI: 10.1002/cne.22163     Document Type: Article

References (48)

1. Bao L, Wang HF, Cai H-J, Tong Y-G, Jin S.-X, Lu Y-J, Grant G, Hökfelt T, Zhang X. 2002. Peripheral axotomy induces only very limited sprouting of coarse myelinated afferents into inner lamina II of rat spinal cord. Eur J Neurosci 16:175-185.
2. Bennett GJ, Xie YK. 1988. A peripheral mononeuropathy in rat that produces disorders of pain sensation like those seen in man. Pain 33:87-107.
3. Braz JM, Nassar MA, Wood JN, Basbaum AI. 2005. Parallel "pain" pathways arise from subpopulations of primary afferent nociceptor. Neuron 47:787-793.
4. Campbell JN, Meyer RA. 2006. Mechanisms of neuropathic pain. Neuron 52:77-92.
5. Chapman V, Suzuki R, Dickenson AH. 1998. Electrophysiological characterization of spinal neuronal properties in anaesthetized rats after ligation of spinal nerves L5-L6. J Physiol 507:881-894.
6. Devor M. 2006. Response of nerves to injury in relation to neuropathic pain. In: McMahon SB, Koltzenburg M, editors. Wall and Melzack's textbook of pain. London: Elsevier. p 905-927.
7. Doubell TP, Mannion RJ, Woolf CJ. 1997. Intact sciatic myelinated primary afferent terminals collaterally sprout in the adult rat dorsal horn following section of a neighbouring peripheral nerve. J Comp Neurol 380: 95-104.
8. Gerke MB, Plenderleith MB. 2004. Ultrastructural analysis of the central terminals of primary sensory neurones labelled by transganglionic transport of Bandeiraea simplicifolia I-isolectin B4. Neuroscience 127: 165-175.
9. Hu J, Mata M, Hao S, Zhang G, Fink DJ. 2004. Central sprouting of uninjured small fiber afferents in the adult rat spinal cord following spinal nerve ligation. Eur J Neurosci 20:1705-1712.
10. Hughes DI, Scott DT, Todd AJ, Riddell JS. 2003. Lack of evidence for sprouting of Aβ afferents into the superficial laminae of the spinal cord dorsal horn following nerve section. J Neurosci 23:9491-9499.
11. Jancsó G, Sántha P, Szigeti C, Dux M. 2004. Selective C-fiber deafferentation of the spinal dorsal horn prevents lesion-induced transganglionic transport of choleragenoid to the substantia gelatinosa in the rat. Neurosci Lett 361:204-207.
12. Ji R-R, Kohno T, Moore K. Woolf CJ. 2003. Central sensitization and LTP: do pain and memory share similar mechanisms? TINS 26:696-705.
13. Kim SH, Chung JM. 1992. An experimental model for peripheral neuropathy produced by segmental spinal nerve ligation in the rat. Pain 50:355-363.
14. Kitchener PD, Wilson P, Snow PJ. 1993. Selective labelling of primary sensory afferent terminals in lamina II of the dorsal horn by injection of Bandeiraea simplicifolia isolectin B4 into peripheral nerves. Neuroscience 154:545-551.
15. Kitchener PD, Lapiz MD, Wilson P, Snow PJ. 1994. Transganglionic labelling of primary sensory afferents in the rat lumbar spinal cord: comparison between wheatgerm agglutinin and the I-B4 isolectin from Bandeiraea simplicifolia. J Neurocytol 23:745-757.
16. LaMotte CC, Kapadia SE, Shapiro CM. 1991. Central projections of the sciatic, saphenous, median, and ulnar nerves of the rat demonstrated by transganglionic transport of choleragenoid-HRP (B-HRP) and wheat germ agglutinin-HRP (WGA-HRP). J Comp Neurol 311:546-562.
17. Llewellyn-Smith IJ, Minson JB. 1992. Complete penetration of antibodies into vibratome sections after glutaraldehyde fixation and ethanol treatment: light and electron microscopy for neuropeptides. J Histochem Cytochem 40:1741-1749.
18. McKenna KE, Nadelhaft I. 1986. The organization of the pudendal nerve in the male and female rat. J Comp Neurol 248:532-549.
19. Ossipov M, Lai J, Porreca F. 2006. Mechanisms of experimental neuropathic pain: integration from animal models. In: McMahon SB, Koltzenburg M. editors. Wall and Melzack's textbook of pain. London: Elsevier. p 929-946.
20. Pacheco P, Camacho MA, García LI, Hernández ME, Carrillo P, Manzo J. 1997. Electrophysiological evidence for the nomenclature of the pudendal nerve and sacral plexus in the male rat. Brain Res 763:202-808.
21. Ribeiro-da-Silva A. 2004. Substantia gelatinosa of the spinal cord. In: Paxinos G, editor. The rat nervous system. Sydney: Elsevier Academic Press. p 129-148.
22. Ribeiro-da-Silva A, De Koninck Y. 2008. Morphological and neurochemical organization of the spinal dorsal horn. In: Bushnell MC, Basbaum AI, editors. Pain. New York: Academic Press. p 279-310.
23. Rivero-Melián C, Grant G. 1990. Distribution of lumbar dorsal root fibers in the lower thoracic and lumbosacral spinal cord of the rat studied with choleragenoid horseradish peroxidase conjugate. J Comp Neurol 299: 470-481.
24. Rivero-Melián C, Grant G. 1991. Choleragenoid horseradish peroxidase used for studying projections of some hindlimb cutaneous nerves and plantar foot afferents to the dorsal horn and Clarke's column in the rat. Exp Brain Res 84:125-132.
25. Robertson B, Grant G. 1985. A comparison between wheatgerm agglutinin and choleragenoid-horseradish peroxidase as anterogradely transported markers in central branches of primary sensory neurones in the rat with some observations in the cat. Neuroscience 14:895-905.
26. Sántha P, Jancsó G. 2003. Transganglionic transport of choleragenoid by capsaicin-sensitive C-fiber afferents to the substantia gelatinosa of the spinal dorsal horn after peripheral nerve section. Neuroscience 116: 621-627.
27. Seltzer Z, Dubner R, Shir Y. 1990. A novel behavioral model of neuropathic pain disorders produced in rats by partial sciatic nerve injury. Pain 43:205-218.
28. Shehab SA, Atkinson ME. 1986. Vasoactive intestinal polypeptide increases in areas of the dorsal horn of the spinal cord from which other neuropeptides are depleted following peripheral axotomy. Exp Brain Res 62:422-430.
29. Shehab SAS, Atkinson ME, Payne JN. 1986. The origins of the sciatic nerve and changes in neuropeptides after axotomy: a double labelling study using retrograde transport of true blue and vasoactive intestinal polypeptide immunohistochemistry. Brain Res 376:180-185.
30. Shehab SAS, Spike RC, Todd AJ. 2003. Evidence against cholera toxin B subunit as a reliable tracer for sprouting of primary afferents following peripheral nerve injury. Brain Res 964:218-227.
31. Shehab SAS, Spike RC, Todd AJ. 2004. Do central terminals of intact myelinated primary afferents sprout into the superficial dorsal horn of rat spinal cord after the injury of a neighbouring peripheral nerve? J Comp Neurol 474:427-437.
32. Shehab SAS, Al-Marashda K, Al-Zahmia A, Abdul-Kareem A, Al-Sultan MAH. 2008. Unmyelinated primary afferents from adjacent spinal nerves intermingle in the spinal dorsal horn: a possible mechanism contributing to neuropathic pain. Brain Res 1208:111-119.
33. Shortland PJ, Woolf CJ. 1993. Chronic peripheral nerve section results in a rearrangement of the central axonal arborization of axotomized A beta primary afferent neurons in the rat spinal cord. J Comp Neurol 330:65-82.
34. Sugiura Y, Lee CL, Perl ER. 1986. Central projections of identified, unmyelinated (C) afferent fibers innervating mammalian skin. Science 234: 358-361.
35. Sugiura Y, Terui N, Hosoya Y. 1989. Difference in distribution of central terminals between visceral and somatic unmyelinated (C) primary afferent fibers. J. Neurophysiol 62:834-840.
36. Swett JE, Woolf CJ. 1985. The somatotopic organization of primary afferent terminals in the superficial laminae of the dorsal horn of the rat spinal cord. J Comp Neurol 231:66-77.
37. Tong Y-G, Wang HF, Ju G, Grant G, Hökfelt T, Zhang X. 1999. Increased uptake and transport of cholera toxin B-subunit in dorsal root ganglion neurons after peripheral axotomy: possible implications for sensory sprouting. J Comp Neurol 404:143-158.
38. Ueyama T, Arakawa H, Mizuno N. 1987. Central distribution of efferent and afferent components of the pudendal nerve in rat. Anat Embryol 177: 37-49.
39. Valtschanoff JG, Weinberg RJ, Rustioni A. 1992. Peripheral injury and anterograde transport of wheat germ agglutinin-horse radish peroxidase to the spinal cord. Neuroscience 3:685-696.
40. Wang H, Rivero-Melián C, Robertson B, Grant G. 1994. Transganglionic transport and binding of the isolectin B4 from Griffonia simplicifolia I in rat primary sensory neurons. Neuroscience 62:539-551.
41. Weinberg RJ, Tracey DJ, Rustioni A. 1990. Extracellular labeling of unmyelinated dorsal root terminals after WGA-HRP injections in spinal ganglia. Brain Res 23:351-355.
42. Willis WD, Coggeshall RE. 1991. Sensory mechanisms of the spinal cord, 2nd ed. New York: Plenum Press.
43. Woodbury CJ, Kullmann FA, McIlwrath SL, Koerber HR. 2008. Identity of myelinated cutaneous sensory neurons projecting to nocireceptive laminae following nerve injury in adult mice. J Comp Neurol 508:500-509.
44. Woolf CJ. 1997. Molecular signals responsible for the reorganization of the synaptic circuitry of the dorsal horn after peripheral nerve injury: the mechanisms of tactile allodynia. In: Borsook D, editor. Molecular neurobiology of pain: Seattle: IASP Press. p 171-200.
45. Woolf CJ, Shortland P, Coggeshall RE. 1992. Peripheral nerve injury triggers central sprouting of myelinated afferents. Nature 355: 75-78.
46. Woolf CJ, Shortland P, Reynolds M, Ridings J, Doubell T, Coggeshall RE. 1995. Reorganization of central terminals of myelinated primary afferents in the rat dorsal horn following peripheral axotomy. J Comp Neurol 360:121-134.
47. Yaksh TL, Sorkin LS. 2005. Mechanisms of neuropathic pain. Curr Med Chem Central Nerv Syst Agents 5:129-140.
48. Ziegler EA, Magerl W, Meyer RA, Treede RD. 1999. Secondary hyperalgesia to punctate mechanical stimuli. Central sensitization to A-fiber nociceptor input. Brain 122:2245-2257.