Inhibition of VEGFR-3 activation in tumor-draining lymph nodes suppresses the outgrowth of lymph node metastases in the MT-450 syngeneic rat breast cancer model

Clinical and Experimental Metastasis

Volumn 31, Issue 3, 2014, Pages 351-365

  Quagliata, Luca ^a   Klusmeier, Sandra ^b   Cremers, Natascha ^a   Pytowski, Bronislaw ^c   Harvey, Alfred ^d   Pettis, Ronald J ^d   Thiele, Wilko ^a,b   Sleeman, Jonathan P ^a,b  

^a UNIVERSITY OF HEIDELBERG   (Germany)

^b KARLSRUHE INSTITUTE OF TECHNOLOGY   (Germany)

^c ELI LILLY AND COMPANY   (United States)

^d BD Technologies   (United States)

Author keywords

Lymph node; Lymphangiogenesis; Lymphatic; Metastasis; VEGF C

Indexed keywords

ALKALINE PHOSPHATASE; HYBRID PROTEIN; VASCULOTROPIN C; VASCULOTROPIN D; VASCULOTROPIN RECEPTOR 3;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; AXILLARY LYMPH NODE; BREAST CANCER; CANCER CELL; CANCER GROWTH; CANCER PROGNOSIS; CONTROLLED STUDY; HUMAN; HUMAN CELL; LUNG METASTASIS; LYMPH NODE METASTASIS; LYMPHANGIOGENESIS; LYMPHATIC DRAINAGE; NONHUMAN; PROTEIN EXPRESSION; PROTEIN FUNCTION; RAT; ANIMAL; BREAST TUMOR; DRUG ANTAGONISM; EXPERIMENTAL MAMMARY NEOPLASM; FEMALE; GENETICS; LUNG TUMOR; LYMPH NODE; METABOLISM; METASTASIS; PATHOLOGY; TRANSCRIPTION INITIATION;

ANIMALS; BREAST NEOPLASMS; FEMALE; HUMANS; LUNG NEOPLASMS; LYMPH NODES; LYMPHATIC METASTASIS; MAMMARY NEOPLASMS, ANIMAL; RATS; TRANSCRIPTIONAL ACTIVATION; VASCULAR ENDOTHELIAL GROWTH FACTOR C; VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR-3;

EID: 84897573183     PISSN: 02620898     EISSN: 15737276     Source Type: Journal    
DOI: 10.1007/s10585-013-9633-2     Document Type: Article

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