IGHV1-69 B cell chronic lymphocytic leukemia antibodies cross-react with HIV-1 and hepatitis C virus antigens as well as intestinal commensal bacteria

PLoS ONE

Volumn 9, Issue 3, 2014, Pages

  Hwang, Kwan Ki ^a   Trama, Ashley M ^a   Kozink, Daniel M ^a   Chen, Xi ^a   Wiehe, Kevin ^a   Cooper, Abby J ^a   Xia, Shi Mao ^a   Wang, Minyue ^a   Marshall, Dawn J ^a   Whitesides, John ^a   Alam, Munir ^a   Tomaras, Georgia D ^a   Allen, Steven L ^c   Rai, Kanti R ^c   McKeating, Jane ^b   Catera, Rosa ^c   Yan, Xiao Jie ^c   Chu, Charles C ^c   Kelsoe, Garnett ^d   Liao, Hua Xin ^a   Chiorazzi, Nicholas ^c   Haynes, Barton F ^a   more..

^a DUKE UNIVERSITY MEDICAL CENTER   (United States)

^b UNIVERSITY OF BIRMINGHAM   (United Kingdom)

^c FEINSTEIN INSTITUTE FOR MEDICAL RESEARCH   (United States)

^d DUKE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

B LYMPHOCYTE RECEPTOR; CANCER ANTIBODY; GLYCOPROTEIN GP 41; HEPATITIS C VIRUS ANTIGEN; HEPATITIS C VIRUS E2 PROTEIN; HUMAN IMMUNODEFICIENCY VIRUS ANTIGEN; IMMUNOGLOBULIN G1 ANTIBODY; IMMUNOGLOBULIN HEAVY VARIABLE 1-69 ANTIBODY; IMMUNOGLOBULIN M; INFLUENZA HEMAGGLUTININ STEM NEUTRALIZING ANTIBODY; LEUCINE; PARAPROTEIN; PHENYLALANINE; RECOMBINANT ANTIBODY; UNCLASSIFIED DRUG; VIRUS ANTIBODY; VIRUS ANTIGEN; VIRUS PROTEIN; HEPATITIS C ANTIGEN; IGHV1-69 B-CELL RECEPTOR, HUMAN; IMMUNOGLOBULIN HEAVY CHAIN; IMMUNOGLOBULIN VARIABLE REGION; LYMPHOCYTE ANTIGEN RECEPTOR; MONOCLONAL ANTIBODY; PROTEIN BINDING; RECOMBINANT PROTEIN;

ALLELE; ANTIBODY PRODUCTION; ANTIGEN SPECIFICITY; ARTICLE; B CELL LEUKEMIA; CELL POPULATION; CHRONIC LYMPHATIC LEUKEMIA; COMMENSAL; CONTROLLED STUDY; CROSS REACTION; GENETIC VARIABILITY; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1 INFECTION; IGHD3 GENE; IGHJ6 GENE; INTESTINE FLORA; LEUKEMIA CELL; MAJOR CLINICAL STUDY; NONHUMAN; ONCOGENE; VIRUS ATTACHMENT; AMINO ACID SEQUENCE; BACTERIUM; CHEMISTRY; HEPACIVIRUS; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; HYBRIDOMA; IMMUNOGLOBULIN VARIABLE REGION; IMMUNOLOGY; INTESTINE; METABOLISM; MICROBIOLOGY; MOLECULAR GENETICS; SEQUENCE ALIGNMENT; SYMBIOSIS; TREATMENT OUTCOME; TUMOR CELL LINE;

ALLELES; AMINO ACID SEQUENCE; ANTIBODIES, MONOCLONAL; ANTIBODIES, NEOPLASM; BACTERIA; CELL LINE, TUMOR; CROSS REACTIONS; HEPACIVIRUS; HEPATITIS C ANTIGENS; HIV ANTIGENS; HIV INFECTIONS; HIV-1; HUMANS; HYBRIDOMAS; IMMUNOGLOBULIN HEAVY CHAINS; IMMUNOGLOBULIN VARIABLE REGION; INTESTINES; LEUKEMIA, LYMPHOCYTIC, CHRONIC, B-CELL; MOLECULAR SEQUENCE DATA; PARAPROTEINS; PROTEIN BINDING; RECEPTORS, ANTIGEN, B-CELL; RECOMBINANT PROTEINS; SEQUENCE ALIGNMENT; SYMBIOSIS; TREATMENT OUTCOME;

EID: 84897535714     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0090725     Document Type: Article

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