Altered causal connectivity of resting state brain networks in amnesic MCI

PLoS ONE

Volumn 9, Issue 3, 2014, Pages

  Liang, Peipeng ^a,b,c   Li, Zhihao ^d   Deshpande, Gopikrishna ^e,f   Wang, Zhiqun ^a,b,c   Hu, Xiaoping ^d   Li, Kuncheng ^a,b,c  

^a CAPITAL MEDICAL UNIVERSITY   (China)

^b Beijing Key Laboratory of Magnetic Resonance Imaging and Brain Informatics   (China)

^c BEIJING UNIVERSITY OF POSTS AND TELECOMMUNICATIONS   (China)

^d Emory University   (United States)

^e AUBURN UNIVERSITY   (United States)

^f AUBURN UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AGED; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; DEFAULT MODE NETWORK; DISEASE ASSOCIATION; DISEASE SEVERITY; DORSAL ATTENTION NETWORK; FEMALE; FRONTOPARIETAL CONTROL NETWORK; HIPPOCAMPAL CORTICAL MEMORY NETWORK; HUMAN; LEARNING TEST; MALE; MILD COGNITIVE IMPAIRMENT; MINI MENTAL STATE EXAMINATION; NERVE CELL NETWORK; NEUROPATHOLOGY; RESTING STATE NETWORK; AMNESIA; ATTENTION; BRAIN; BRAIN CORTEX; DEMOGRAPHY; HEAD; MEMORY; MOTION; NEUROPSYCHOLOGICAL TEST; PATHOPHYSIOLOGY; PHYSIOLOGY; REST;

AGED; AMNESIA; ATTENTION; BRAIN; CEREBRAL CORTEX; DEMOGRAPHY; FEMALE; HEAD; HUMANS; MALE; MEMORY; MILD COGNITIVE IMPAIRMENT; MOTION; NERVE NET; NEUROPSYCHOLOGICAL TESTS; REST;

EID: 84897531786     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0088476     Document Type: Article

References (88)

1. Braak H, Braak E (1991) Neuropathological stageing of Alzheimer-related changes. Acta Neuropathol 82: 239-259.
2. Petersen RC, Doody R, Kurz A, Mohs RC, Morris JC, et al. (2001) Current concepts in mild cognitive impairment. Arch Neurol 58: 1985-1992. (Pubitemid 33143977)
3. Morrison JH, Scherr S, Lewis DA, Campbell MJ, Bloom FE, et al. (1986) The laminar and regional distribution of neocortical somatostatin and neuritic plaques: Implications for Alzheimer's disease as a global neocortical disconnection syndrome. The Biological Substrates of Alzheimer's Disease, Academic Press, Orlando 115-131.
4. De Lacoste MC, White III CL (1993) The role of cortical connectivity in Alzheimer's disease pathogenesis: a review and model system. Neurobiol Aging 14: 1-16.
5. Delbeuck X, Van der Linden M, Collette F (2003) Alzheimer's disease as a disconnection syndrome? Neuropsychol Rev 13: 79-92. (Pubitemid 38113373)
6. Gomez-Isla T, Hyman BT (1997) Connections and cognitive impairment in Alzheimer's disease. In: Hyman BT, Duyckaerts C, Christen Y, editors. Connections, Cognition, and Alzheimer's Disease. Berlin: Springer 149-166.
7. Wang L, Zang YF, He Y, Liang M, Zhang XQ, et al. (2006) Changes in hippocampal connectivity in the early stages of Alzheimer's disease: Evidence from resting state fMRI. NeuroImage 31: 496-504. (Pubitemid 43776683)
8. Wang K, Liang M, Wang L, Tian LX, Zhang XQ, et al. (2007) Altered functional connectivity in early Alzheimer's disease: A resting-state fMRI study. Human Brain Mapping 28: 967-978. (Pubitemid 47549702)
9. Sorg C, Riedl V, Muhlau M, Calhoun VD, Eichele T, et al. (2007) Selective changes of resting-state networks in individuals at risk for Alzheimer's disease. Proc Natl Acad Sci USA 104: 18760-18765. (Pubitemid 350210770)
10. Bai F, Zhang Z, Yu H, Shi Y, Yuan Y, et al. (2008) Default-mode network activity distinguishes amnestic type mild cognitive impairment from healthy aging: a combined structural and resting-state functional MRI study. Neurosci Letters 438: 111-115.
11. Bai F, Watson DR, Yu H, Shi Y, Yuan Y, et al. (2009) Abnormal resting-state functional connectivity of posterior cingulate cortex in amnestic type mild cognitive impairment. Brain Res 1302: 167-174.
12. Bai F, Watson DR, Shi Y, Wang Y, Yue C, et al. (2011) Specifically progressive deficits of brain functional marker in amnestic type mild cognitive impairment. PLoS One 6: e24271.
13. Zhang HY, Wang SJ, Xing J, Liu B, Ma ZL, et al. (2009) Detection of PCC functional connectivity characteristics in resting-state fMRI in mild Alzheimer's disease. Behav Brain Res 197: 103-108.
14. Zhang ZS, Deng LL, Bai F, Shi YM, Yu H, et al. (2010) Alteration of resting brain function by genetic variation in angiotensin converting enzyme in amnestic-type mild cognitive impairment of Chinese Han. Behavioural Brain Research 208: 619-625.
15. Greicius MD, Srivastava G, Reiss AL, Menon V (2004) Default-mode network activity distinguishes Alzheimer's disease from healthy aging: evidence from functional MRI. Proc Natl Acad Sci USA 101: 4637-4642. (Pubitemid 38437463)
16. Qi Z, Wu X, Wang Z, Zhang N, Dong H, et al. (2010) Impairment and compensation coexist in amnestic MCI default mode network. Neuroimage 50: 48-55.
17. Celone KA, Calhoun VD, Dickerson BC, Atri A, Chua EF, et al. (2006) Alterations in memory networks in mild cognitive impairment and Alzheimer's disease: an independent component analysis. J Neurosci 26: 10222-10231. (Pubitemid 44527415)
18. Allen G, Barnard H, McColl R, Hester AL, Fields JA, et al. (2007) Reduced hippocampal functional connectivity in Alzheimer disease. Arch Neurol 64: 1482-1487. (Pubitemid 47572671)
19. Wang Z, Liang P, Jia X, Qi Z, Yu L, et al. (2011) Baseline and longitudinal patterns of hippocampal connectivity in mild cognitive impairment: evidence from resting state fMRI. J Neurol Sci 309: 79-85.
20. Liang P, Wang Z, Yang Y, Jia X, Li K (2011) Functional disconnection and compensation in mild cognitive impairment: Evidence from DLPFC connectivity using resting-state fMRI. PLoS ONE 6: e22153.
21. Liang P, Wang Z, Yang Y, Li K (2012) Three Subsystems of the Inferior Parietal Cortex are Differently Affected in Mild Cognitive Impairment. Journal of Alzheimer's Disease 30: 475-487.
22. Deshpande G, Li Z, Santhanam P, Coles CD, Lynch ME, et al. (2010) Recursive cluster elimination based support vector machine for disease state prediction using resting state functional and effective brain connectivity. PLoS One 5: e14277.
23. Liu Z, Zhang Y, Bai L, Yan H, Dai R, et al. (2012) Investigation of the effective connectivity of resting state networks in Alzheimer's disease: a functional MRI study combining independent components analysis and multivariate Granger causality analysis. NMR Biomed 25: 1311-1320.
24. Miao X, Wu X, Li R, Chen K, Yao L (2011) Altered Connectivity Pattern of Hubs in Default-Mode Network with Alzheimer's Disease: An Granger Causality Modeling Approach. PLoS ONE 6: e25546.
25. Wu X, Li R, Fleisher AS, Reiman EM, Guan X, et al. (2011) Altered default mode network connectivity in Alzheimer's disease-a resting functional MRI and Bayesian network study. Hum Brain Mapp 32: 1868-1881.
26. Li R, Wu X, Chen K, Fleisher AS, Reiman EM, et al. (2013) Alterations of directional connectivity among resting-state networks in Alzheimer Disease. AJNR Am J Neuroradiol 34: 340-345.
27. Sridharan D, Levitin DJ, Menon V (2008) A critical role for the right fronto-insular cortex in switching between central-executive and default-mode networks. Proc Natl Acad Sci USA 105: 12569-12574.
28. Uddin A, Kelly C, Biswal B, Castallanos F, Milham M (2009) Functional connectivity of default-mode network components: correlation, anticorrelation, and causality. Hum Brain Mapp 30: 625-637.
29. Deshpande G, Sathian K, Hu X (2010) Assessing and compensating for zero-lag correlation effects in time-lagged Granger causality analysis of fMRI. IEEE Transactions on Biomedical Engineering 57: 1446-1456.
30. Grecius M, Krasnow B, Reiss A, Menon V (2003) Functional connectivity in the resting brain: a network analysis of the default mode hypothesis. Proc Natl Acad Sci USA 100: 253-258. (Pubitemid 36078061)
31. Raichle ME, Macleod AM, Snyder AZ, Powers WJ, Gusnard DA, et al. (2001) A default mode of brain function. Proc Natl Acad Sci USA 98: 676-682. (Pubitemid 32105102)
32. Fox M, Corbetta M, Snyder A, Vincent J, Raichle M (2006) Spntaneous neuronal activity distinguishes human dorsal and ventral attention systems. Proc Natl Acad Sci USA 103: 10046-10051. (Pubitemid 43993620)
33. Vincent JL, Kahn I, Snyder AZ, Raichle ME, Buckner RL (2008) Evidence for a Frontoparietal Control System Revealed by Intrinsic Functional Connectivity. Journal of Neurophysiology 100: 3328-3342.
34. Fox MD, Snyder AZ, Vincent JL, Corbetta M, Van Essen DC, et al. (2005) The human brain is intrinsically organized into dynamic, anticorrelated functional networks. Proc Natl Acad Sci USA 102: 9673-9678. (Pubitemid 40981739)
35. Fransson P (2005) Spontaneous low-frequency BOLD signal fluctuations: an fMRI investigation of the resting-state default mode of brain function hypothesis. Human Brain Mapping 26: 15-29.
36. Spreng R, Stevens W, Chamberlain J, Gilmore A, Schacter D (2010) Default network activity, coupled with frontoparietal control network, supports goal-directed cognition. Neuroimage 53: 303-317.
37. Deshpande G, Sathian K, Hu X (2010) Effect of hemodynamic variability on Granger causality analysis of fMRI. Neuroimage 52: 884-896.
38. Deshpande G, Hu X, Lacey S, Stilla R, Sathian K (2010) Object familiarity modulates effective connectivity during haptic shape perception. Neuroimage 49: 1991-2000.
39. Rosano C, Aizenstein HJ, Cochran JL, Saxton JA, De Kosky ST, et al. (2005) Event-related functional magnetic resonance imaging investigation of executive control in very old individuals with mild cognitive impairment. Biol Psychiatry 57: 761-767. (Pubitemid 40487920)
40. Clément F, Belleville S, Mellah S (2010) Functional neuroanatomy of the encoding and retrieval processes of verbal episodic memory in MCI. Cortex 46: 1005-1015.
41. Yang YH, Liang PP, Lu SF, Li KC, Zhong N (2009) The role of the DLPFC in inductive reasoning of MCI patients and normal agings: An fMRI study. Science in China Series C: Life Sciences 52: 789-795.
42. Mosconi L, Tsui W-H, De Santi S, Li J, Rusinek H, et al. (2005) Reduced hippocampal metabolism in MCI and AD: automated FDG-PET image analysis. Neurology 64: 1860-1867. (Pubitemid 40800698)
43. Mosconi L, De Santi S, Li J, Tsui WH, Li Y, et al. (2008) Hippocampal hypometabolism predicts cognitive decline from normal aging. Neurobiol Aging 29: 676-692. (Pubitemid 351400830)
44. Wang J, Zuo X, Dai Z, Xia M, Zhao Z, et al. (2012) Disrupted functional brain connectome in individuals at risk for Alzheimer's disease. Biol Psychiat 73: 472- 481.
45. Petersen RC, Smith GE, Waring SC, Ivnik RJ, Tangalos EG, et al. (1999) Mild cognitive impairment, clinical characterization and outcome. Archives of Neurology 56: 303-308. (Pubitemid 29120227)
46. Ashburner J, Friston KJ (2005) Unified segmentation. NeuroImage 26: 839-851. (Pubitemid 40825026)
47. Biswal B, Yetkin FZ, Haughton VM, Hyde JS (1995) Functional connectivity in the motor cortex of resting human brain using echo-planar MRI. Magn. Reson. Med 34: 537-541.
48. Bokde AL, Pietrini P, Ibanez V, Furey ML, Alexander GE, et al. (2001) The effect of brain atrophy on cerebral hypometabolism in the visual variant of Alzheimer disease. Arch Neurol 58: 480-486. (Pubitemid 32217466)
49. Oakes TR, Fox AS, Johnstone T, Chung MK, Kalin N, et al. (2007) Integrating VBM into the general linear model with voxelwise anatomical covariates. NeuroImage 34: 500-508. (Pubitemid 44827773)
50. He Y, Wang L, Zang Y, Tian L, Zhang X, et al. (2007) Regional coherence changes in the early stages of Alzheimer's disease: a combined structural and resting-state functional MRI study. NeuroImage 35: 488-500. (Pubitemid 46400540)
51. Deshpande G, Santhanam P, Hu X (2011) Instantaneous and causal connectivity in resting state brain networks derived from functional MRI data. NeuroImage 54: 1043-1052.
52. Schwartz G (1978) Estimating the dimension of a model. Ann Stat 5: 461-464.
53. Deshpande G, LaConte S, James G, Peltier S, Hu X (2009) Multivariate Granger causality analysis of brain networks. Hum. Brain Mapp 30: 1361-1373.
54. Theiler J, Eubank S, Longtin A, Galdrikian B, Farmer D (1992) Testing for nonlinearity in time series: the method of surrogate data. Physica D 58: 77-94.
55. Derflinger S, Sorg C, Gaser C, Myers N, Arsic M, et al. (2011) Grey-matter atrophy in Alzheimer's disease is asymmetric but not lateralized. J Alzheimers Dis 25: 347-357.
56. Yang J, Pan P, Song W, Huang R, Li J, et al. (2012) Voxelwise meta-analysis of gray matter anomalies in Alzheimer's disease and mild cognitive impairment using anatomic likelihood estimation. J Neurol Sci 316: 21-29.
57. Schölvinck ML, Maier A, Ye FQ, Duyn JH, Leopold DA (2010) Neural basis of global resting-state fMRI activity. Proc Natl Acad Sci USA 107: 10238-10243.
58. Fox MD, Zhang D, Snyder AZ, Raichle ME (2009) The global signal and observed anticorrelated resting state brain networks. J Neurophysiol 101: 3270-3283.
59. Murphy K, Birn RM, Handwerker DA, Jones TB, Bandettini PA (2009) The impact of global signal regression on resting state correlations: are anti-correlated networks introduced? NeuroImage 44: 893-905.
60. Weissenbacher A, Kasess C, Gerstl F, Lanzenberger R, Moser E, et al. (2009) Correlations and anticorrelations in resting-state functional connectivity MRI: a quantitative comparison of preprocessing strategies. Neuroimage 47: 1408-1416.
61. Chai XJ, Castañón AN, Ongür D, Whitfield-Gabrieli S (2012) Anticorrelations in resting state networks without global signal regression. NeuroImage 59: 1420-1428.
62. Power JD, Barnes K, Snyder A, Schlaggar B, Petersen S (2012) Spurious but systematic correlations in functional connectivity MRI networks arise from subject motion. NeuroImage 59: 2142-2154.
63. Satterthwaite TD, Wolf DH, Loughead J, Ruparel K, Elliott MA, et al. (2012) Impact of in-scanner head motion on multiple measures of functional connectivity: relevance for studies of neurodevelopment in youth. NeuroImage 60: 623-632.
64. Satterthwaite TD, Elliott MA, Gerraty RT, Ruparel K, Loughead J, et al. (2013) An improved framework for confound regression and filtering for control of motion artifact in the preprocessing of resting-state functional connectivity data. NeuroImage 64: 240-256.
65. Van Dijk KRA, Sabuncu MR, Buckner RL (2012) The influence of head motion on intrinsic functional connectivity MRI. NeuroImage 59: 431-438.
66. Yan CG, Cheung B, Kelly C, Colcombe S, Craddock RC, et al. (2013) A comprehensive assessment of regional variation in the impact of head micromovements on functional connectomics. NeuroImage 76: 183-201.
67. Belleville S, Bherer L, Lepage É, Chertkow H, Gauthier S (2008) Task switching capacities in persons with Alzheimer's disease and mild cognitive impairment. Neuropsychologia 46: 2225-2233.
68. Marshall GA, Rentz DM, Frey MT, Locascio JJ, Johnson KA, et al. (2011) Executive function and instrumental activities of daily living in mild cognitive impairment and Alzheimer's disease. Alzheimer's & Dementia 7: 300-308.
69. Thomann PA, Toro P, Dos Santos V, Essig M, Schröder J (2008) Clock drawing performance and brain morphology in mild cognitive impairment and Alzheimer's disease. Brain and Cognition 67: 88-93.
70. Ramnani N, Owen A (2004) Anterior prefrontal cortex: insights into function from anatomy and neuroimaging. Nat. Rev. Neurosci 5: 184-194. (Pubitemid 38252475)
71. Christoff K, Gabrieli J (2000) The frontopolar cortex and human cognition: evidence for a rostrocaudal heirarchical organisation within the human prefrontal cortex. Psychobiology 28: 168-186. (Pubitemid 30480473)
72. Koechlin E, Basso G, Pietrini P, Panzer S, Grafman J (1999) The role of the anterior prefrontal cortex in human cognition. Nature 399: 148-151.
73. Rombouts SA, Barkhof F, Goekoop R, Stam CJ, Scheltens P (2005) Altered resting state networks in mild cognitive impairment and mild Alzheimer's disease: An fMRI study. Human Brain Mapping 26: 231-239. (Pubitemid 41759880)
74. Petrella JR, Wang L, Krishnan S, Slavin MJ, Prince SE, et al. (2007) Cortical deactivation in mild cognitive impairment: High-field-strength functional MR imaging. Neuroradiology 245: 224-234.
75. Buckner R, Andrews-Hanna J, Schacter D (2008) The brain's default network: anatomy, function and relevance to disease. Ann NY Acad Sci 1124: 1-38. (Pubitemid 351506788)
76. Ferreira LK, Diniz BS, Forlenza OV, Busatto GF, Zanetti MV (2011) Neurostructural predictors of Alzheimer's disease: a meta-analysis of VBM studies. Neurobiol Aging 32: 1733-1741.
77. Nickl-Jockschat T, Kleiman A, Schulz JB, Schneider F, Laird AR, et al. (2012) Neuroanatomic changes and their association with cognitive decline in mild cognitive impairment: a meta-analysis. Brain Struct Funct 217: 115-125.
78. Huijbers W, Pennartz CMA, Cabeza R, Daselaar SM (2011) The Hippocampus Is Coupled with the Default Network during Memory Retrieval but Not during Memory Encoding. PLoS ONE 6: e17463.
79. Wang L, Laviolette P, O'Keefe K, Putcha D, Bakkour A, et al. (2010) Intrinsic connectivity between the hippocampus and posteromedial cortex predicts memory performance in cognitively intact older individuals. Neuroimage 51: 910-917.
80. Putcha D, Brickhouse M, O'Keefe K, Sullivan C, Rentz D, et al. (2011) Hippocampal hyperactivation associated with cortical thinning in Alzheimer's disease signature regions in non-demented elderly adults. J Neurosci 31: 17680- 17688.
81. Hamalainen A, Pihlajamaki M, Tanila H, Hanninen T, Niskanen E, et al. (2006) Increased fMRI responses during encoding in mild cognitive impairment. Neurobiology of Aging 28: 1889-1903.
82. Kircher T, Weis S, Freymann K, Erb M, Jessen F, et al. (2007) Hippocampal activation in MCI patients is necessary for successful memory encoding. Journal of Neurology, Neurosurgery, and Psychiatry 78: 812-818. (Pubitemid 47204583)
83. Clément F, Belleville S (2010) Compensation and disease severity on the memory-related activations in mild cognitive impairment. Biol Psychiatry 68: 894-902.
84. Agosta F, Pievani M, Geroldi C, Copetti M, Frisoni GB, et al. (2012) Resting state fMRI in Alzheimer's disease: beyond the default mode network. Neurobiol Aging 33: 1564-1578.
85. Bonnelle V, Ham TE, Leech R, Kinnunen KM, Mehta MA, et al. (2012) Salience network integrity predicts default mode network function after traumatic brain injury. Proc Natl Acad Sci U S A 109: 4690-4695.
86. Wen X, Liu Y, Yao L, Ding M (2013) Top-down regulation of default mode activity in spatial visual attention. The Journal of Neuroscience 33: 6444-6453.
87. Delamillieure P, Doucet G, Mazoyer B, Turbelin MR, Delcroix N, et al. (2010) The resting state questionnaire: An introspective questionnaire for evaluation of inner experience during the conscious resting state. Brain Res Bull 81: 565-573.
88. Liao XH, Xia MR, Xu T, Dai ZJ, Cao XY, et al. (2013) Functional brain hubs and their test-retest reliability: A multiband resting-state functional MRI study. Neuroimage 83: 969-982.