Grey-matter atrophy in Alzheimer's disease is asymmetric but not lateralized

Journal of Alzheimer's Disease

Volumn 25, Issue 2, 2011, Pages 347-357

  Derflinger, Sabine ^a   Gaser, Christian ^b   Myers, Nicholas ^a,c   Arsic, Milan ^a   Kurz, Alexander ^a   Zimmer, Claus ^a   Wohlschläger, Afra ^a   Mühlau, Mark ^a  

^a TECHNICAL UNIVERSITY OF MUNICH   (Germany)

^b FRIEDRICH SCHILLER UNIVERSITY JENA   (Germany)

^c UNIVERSITY OF MUNICH   (Germany)

Author keywords

Alzheimer's disease; asymmetry; CERAD; lateralization; voxel based morphometry

Indexed keywords

AGED; ALZHEIMER DISEASE; ARTICLE; BRAIN ASYMMETRY; BRAIN ATROPHY; COGNITIVE DEFECT; CONTROLLED STUDY; CORRELATION ANALYSIS; ENTORHINAL CORTEX; FEMALE; FRONTAL CORTEX; GRAY MATTER; HEMISPHERIC DOMINANCE; HUMAN; INDIVIDUALIZATION; LANGUAGE TEST; MAJOR CLINICAL STUDY; MALE; MILD COGNITIVE IMPAIRMENT; NEUROPSYCHOLOGICAL TEST; OCCIPITAL CORTEX; PARIETAL CORTEX; PRECUNEUS; PRIORITY JOURNAL; RISK; TASK PERFORMANCE; VOXEL BASED MORPHOMETRY;

EID: 79960705828     PISSN: 13872877     EISSN: 18758908     Source Type: Journal    
DOI: 10.3233/JAD-2011-110041     Document Type: Article

References (57)

1. Querfurth HW, La Ferla FM (2010) Alzheimer's disease. N Engl J Med 362, 329-344.
2. Hutsler J, Galuske RA (2003) Hemispheric asymmetries in cerebral cortical networks. Trends Neurosci 26, 429-435. (Pubitemid 37288978)
3. Kristofikova Z, Kozmikova I, Hovorkova P, Ricny J, Zach P, Majer E, Klaschka J, Ripova D (2008) Lateralization of hippocampal nitric oxide mediator system in people with Alzheimer disease, multi-infarct dementia and schizophrenia. Neurochem Int 53, 118-125.
4. Toga AW, Thompson PM (2003) Mapping brain asymmetry. Nat Rev Neurosci 4, 37-48. (Pubitemid 37271087)
5. Steinmetz H (1996) Structure, functional and cerebral asymmetry: in vivo morphometry of the planum temporale. Neurosci Biobehav Rev 20, 587-591. (Pubitemid 27043860)
6. Uitti RJ, Baba Y, Whaley NR, Wszolek ZK, Putzke JD (2005) Parkinson disease: handedness predicts asymmetry. Neurology 64, 1925-1930. (Pubitemid 40800708)
7. Mesulam MM (2003) Primary progressive aphasia - a language-based dementia. N Engl J Med 349, 1535-1542.
8. Xeno Rasmusson D, Brandt J (1995) Instability of cognitive asymmetry in Alzheimer's disease. J Clin Exp Neuropsychol 17, 449-458.
9. Massman PJ, Doody RS (1996) Hemispheric asymmetry in Alzheimer's disease is apparent in motor functioning. J Clin Exp Neuropsychol 18, 110-121. (Pubitemid 26066961)
10. Strite D, Massman PJ, Cooke N, Doody RS (1997) Neuropsy-chological asymmetry in Alzheimer's disease: verbal versus visuoconstructional deficits across stages of dementia. J Int Neuropsychol Soc 3, 420-427. (Pubitemid 27429699)
11. Capitani E, Della Sala S, Spinnler H (1990) Controversial neuropsychological issues in Alzheimer's disease: influence of onset-age and hemispheric asymmetryof impairment. Cortex 26, 133-145. (Pubitemid 20174875)
12. Doody RS, Vacca JL, Massman PJ, Liao TY (1999) The influence of handedness on the clinical presentation and neuropsychology of Alzheimer disease. Arch Neurol 56, 1133-1137. (Pubitemid 29426801)
13. Friedland RP, Budinger TF, Koss E, Ober BA (1985) Alzheimer's disease: anterior-posterior and lateral hemispheric alterations in cortical glucose utilization. Neurosci Lett 53, 235-240. (Pubitemid 15161337)
14. Haxby JV, Duara R, Grady CL, Cutler NR, Rapoport SI (1985) Relations between neuropsychological and cerebral metabolic asymmetries in early Alzheimer's disease. J Cereb Blood Flow Metab 5, 193-200. (Pubitemid 15123204)
15. Haxby JV, Grady CL, Koss E, Horwitz B, Heston L, Schapiro M, Friedland RP, Rapoport SI (1990) Longitudinal study of cerebral metabolic asymmetries and associated neuropsycho-logical patterns in early dementia of the Alzheimer type. Arch Neurol 47, 753-760. (Pubitemid 20208615)
16. Kovalev VA, Thurfjell L, Lundqvist R, Pagani M (2006) Asymmetry of SPECT perfusion image patterns as a diagnostic feature for Alzheimer's disease. Med Image Comput Comput Assist Interv 9, 421-428. (Pubitemid 44609248)
17. Meguro K, Shimada M, Someya K, Horikawa A, Yamadori A (2001) Hemispatial visual-searching impairment correlated with decreased contralateral parietal blood flow in Alzheimer disease. Neuropsychiatry Neuropsychol Behav Neurol 14, 213-218. (Pubitemid 33051497)
18. Volkow ND, Zhu W, Felder CA, Mueller K, Welsh TF, Wang GJ, de Leon MJ (2002) Changes in brain functional homogeneity in subjects with Alzheimer's disease. Psychiatry Res 114, 39-50. (Pubitemid 34178345)
19. Keilp JG, Alexander GE, Stern Y, Prohovnik I (1996) Inferior parietal perfusion, lateralization, and neuropsycho-logical dysfunction in Alzheimer's disease. Brain Cogn 32, 365-383. (Pubitemid 27047566)
20. Duara R, Grady C, Haxby J, Sundaram M, Cutler NR, Heston L, Moore A, Schlageter N, Larson S, Rapoport SI (1986) Positron emission tomography in Alzheimer's disease. Neurology 36, 879-887. (Pubitemid 16098229)
21. Zahn R, Juengling F, Bubrowski P, Jost E, Dykierek P, Talazko J, Huell M (2004) Hemispheric asymmetries of hypometabolism associated with semantic memory impairment in Alzheimer's disease: a study using positron emission tomography with fluorodeoxyglucose-F18. Psychiatry Res 132, 159-172. (Pubitemid 39643013)
22. Loewenstein DA, Barker WW, Chang JY, Apicella A, Yoshii F, Kothari P, Levin B, Duara R (1989) Predominant left hemisphere metabolic dysfunction in dementia. Arch Neurol 46, 146-152. (Pubitemid 19051264)
23. Janke AL, de Zubicaray G, Rose SE, Griffin M, Chalk JB, Galloway GJ (2001) 4D deformation modeling of cortical disease progression in Alzheimer's dementia. Magn Reson Med 46, 661-666. (Pubitemid 32906134)
24. Thompson PM, Hayashi KM, de Zubicaray G, Janke AL, Rose SE, Semple J, Herman D, Hong MS, Dittmer SS, Doddrell DM, Toga AW (2003) Dynamics of gray matter loss in Alzheimer's disease. J Neurosci 23, 994-1005. (Pubitemid 36206191)
25. Thompson PM, Mega MS, Woods RP, Zoumalan CI, Lindshield CJ, Blanton RE, Moussai J, Holmes CJ, Cummings JL, Toga AW (2001) Cortical change in Alzheimer's disease detected with a disease-specific population-based brain atlas. Cereb Cortex 11, 1-16. (Pubitemid 32064172)
26. Thompson PM, Moussai J, Zohoori S, Goldkorn A, Khan AA, Mega MS, Small GW, Cummings JL, Toga AW (1998) Cortical variability and asymmetry in normal aging and Alzheimer's disease. Cereb Cortex 8, 492-509. (Pubitemid 28420599)
27. Shi F, Liu B, Zhou Y, Yu C, Jiang T (2009) Hippocam-pal volume and asymmetry in mild cognitive impairment and Alzheimer's disease: meta-analyses of MRI studies. Hippocampus 19, 1055-1064.
28. Janota I, Mountjoy CQ (1988) Asymmetry of pathology in Alzheimer's disease. J Neurol Neurosurg Psychiatry 51, 1011-1012.
29. Wilcock GK, Esiri MM (1987) Asymmetry of pathology in Alzheimer's disease. J Neurol Neurosurg Psychiatry 50, 1384-1386. (Pubitemid 17150717)
30. Moossy J, Zubenko GS, Martinez AJ, Rao GR, Kopp U, Hanin I (1989) Lateralization of brain morphologic and cholinergicabnormalitiesin Alzheimer's disease.Arch Neurol 46, 639-642. (Pubitemid 19150942)
31. Raji CA, Becker JT, Tsopelas ND, Price JC, Mathis CA, Saxton JA, Lopresti BJ, Hoge JA, Ziolko SK, De Kosky ST, Klunk WE (2008) Characterizing regional correlation, later-ality and symmetry of amyloid deposition in mild cognitive impairment and Alzheimer's disease with Pittsburgh Compound B. J Neurosci Methods 172, 277-282.
32. Tsai KJ, Yang CH, Lee PC, Wang WT, Chiu MJ, Shen CK (2009) Asymmetric expression patterns of brain transthyretin in normal mice and a transgenic mouse model of Alzheimer's disease. Neuroscience 159, 638-646.
33. Gauthier S, Reisberg B, Zaudig M, Petersen RC, Ritchie K, Broich K, Belleville S, Brodaty H, Bennett D, Chertkow H, Cummings JL, de Leon M, Feldman H, Ganguli M, Hampel H, Scheltens P, Tierney MC, Whitehouse P, Winblad B (2006) Mild cognitive impairment. Lancet 367, 1262-1270.
34. Petersen RC, Smith GE, Waring SC, Ivnik RJ, Tangalos EG, Kokmen E (1999) Mild cognitive impairment: clinical characterization and outcome. Arch Neurol 56, 303-308. (Pubitemid 29120227)
35. Petersen RC, Negash S (2008) Mild cognitive impairment: an overview. CNS Spectr 13, 45-53. (Pubitemid 351224282)
36. McKhann G, Drachman D, Folstein M, Katzman R, Price D, Stadlan EM (1984) Clinical diagnosis of Alzheimer's disease: report of the NINCDS-ADRDA Work Group under the auspices of Department of Health and Human Services Task Force on Alzheimer's Disease. Neurology 34, 939-944. (Pubitemid 14076461)
37. Bozzali M, Filippi M, Magnani G, Cercignani M, Franceschi M, Schiatti E, Castiglioni S, Mossini R, Falautano M, Scotti G, Comi G, Falini A(2006) The contributionofvoxel-based mor-phometry in staging patients with mild cognitive impairment. Neurology 67, 453-460. (Pubitemid 44214970)
38. Ashburner J, Friston KJ (2005) Unified segmentation. Neuroimage 26, 839-851. (Pubitemid 40825026)
39. Tohka J, Zijdenbos A, Evans A (2004) Fast and robust parameter estimation for statistical partial volume models in brain MRI. Neuroimage 23, 84-97. (Pubitemid 39119438)
40. Rajapakse JC, Giedd JN, Rapoport JL (1997) Statistical approach to segmentation of single-channel cerebral MR images. IEEE Trans Med Imaging 16, 176-186. (Pubitemid 127762929)
41. Cuadra MB, Cammoun L, Butz T, Cuisenaire O, Thiran JP (2005) Comparison and validation of tissue modelization and statistical classification methods in T1-weighted MR brain images. IEEE Trans Med Imaging 24, 1548-1565. (Pubitemid 41812023)
42. Lüders E, Gaser C, Narr KL, Toga AW (2009) Why sex matters: brain size independent differences in gray matter distributions between men and women. J Neurosci 29, 14265-14270.
43. Lüders E, Gaser C, Jancke L, Schlaug G (2004) A voxel-based approach to gray matter asymmetries. Neuroimage 22, 656-664. (Pubitemid 38759428)
44. Maldjian JA, Laurienti PJ, Kraft RA, Burdette JH (2003) An automated method for neuroanatomic and cytoarchitectonic atlas-based interrogation of f MRI data sets. Neuroimage 19, 1233-1239. (Pubitemid 36918259)
45. Smith SM, Nichols TE (2009) Threshold-free cluster enhancement: addressing problems of smoothing, threshold dependence and localisation in cluster inference. Neuroimage 44, 83-98.
46. Mitchell J, Arnold R, Dawson K, Nestor PJ, Hodges JR (2009) Outcome in subgroups of mild cognitive impairment (MCI) is highly predictable using a simple algorithm. J Neurol 256, 1500-1509.
47. Chetelat G, Desgranges B, De La Sayette V, Viader F, Eustache F, Baron JC (2002) Mapping gray matter loss with voxel-based morphometryinmild cognitive impairment.Neu-roreport 13, 1939-1943. (Pubitemid 35398965)
48. Chetelat G, Landeau B, Eustache F, Mezenge F, Viader F, de la Sayette V, Desgranges B, Baron JC (2005) Using voxel-based morphometry to map the structural changes associated with rapid conversion in MCI: a longitudinal MRI study. Neuroimage 27, 934-946. (Pubitemid 41317262)
49. Karas G, Sluimer J, Goekoop R, van der Flier W, Rombouts SA, Vrenken H, Scheltens P, Fox N, Barkhof F(2008) Amnestic mild cognitive impairment: structural MRimagingfindings predictive of conversion to Alzheimer disease. AJNR Am J Neuroradiol 29, 944-949. (Pubitemid 351684972)
50. Karas GB, Burton EJ, Rombouts SA, van Schijndel RA, O'Brien JT, Scheltens P, McKeith IG, Williams D, Ballard C, Barkhof F (2003) A comprehensive study of gray matter loss in patients with Alzheimer's disease using optimized voxel-based morphometry. Neuroimage 18, 895-907. (Pubitemid 36513463)
51. Karas GB, Scheltens P, Rombouts SA, Visser PJ, van Schijn-del RA, Fox NC, Barkhof F (2004) Global and local gray matter loss in mild cognitive impairment and Alzheimer's disease. Neuroimage 23, 708-716. (Pubitemid 39370621)
52. Pennanen C, Testa C, Laakso MP, Hallikainen M, Helkala EL, Hanninen T, Kivipelto M, Kononen M, Nissinen A, Tervo S, Vanhanen M, Vanninen R, Frisoni GB, Soininen H (2005) A voxel based morphometry study on mild cognitive impairment. J Neurol Neurosurg Psychiatry 76, 11-14. (Pubitemid 40013484)
53. Ullman MT (2001) A neurocognitive perspective on language: the declarative/procedural model. Nat Rev Neurosci 2, 717-726. (Pubitemid 33674817)
54. Hickok G, Poeppel D (2000) Towards a functional neu-roanatomy of speech perception. Trends Cogn Sci 4, 131-138. (Pubitemid 30182529)
55. Leff AP, Schofield TM, Crinion JT, Seghier ML, Grogan A, Green DW, Price CJ(2009) The left superior temporal gyrus is a shared substrate for auditory short-term memory and speech comprehension: evidence from 210 patients with stroke.Brain 132, 3401-3410.
56. Apostolova LG, Lu P, Rogers S, Dutton RA, Hayashi KM, Toga AW, Cummings JL, Thompson PM (2008) 3D mapping of language networks in clinical and pre-clinical Alzheimer's disease. Brain Lang 104, 33-41. (Pubitemid 350088966)
57. Teipel SJ, Willoch F, Ishii K, Burger K, Drzezga A, Engel R, Bartenstein P, Moller HJ, Schwaiger M, Hampel H (2006) Resting state glucose utilization and the CERAD cognitive battery in patients with Alzheimer's disease. Neurobiol Aging 27, 681-690.