Principle considerations for the risk assessment of sprayed consumer products

Toxicology Letters

Volumn 227, Issue 1, 2014, Pages 41-49

  Steiling, W ^a   Bascompta, M ^b   Carthew, P ^c   Catalano, G ^d   Corea, N ^e   D'Haese, A ^f   Jackson, P ^g   Kromidas, L ^h   Meurice, P ⁱ   Rothe, H ^j   Singal, M ^h,k  

^a HENKEL KGAA   (Germany)

^b Montana Air SL ^*  (Spain)

^c UNILEVER RESEARCH   (United Kingdom)

^d Ardagh Group   (Italy)

^e S C Johnson & Son Inc   (United States)

^f FEA European Aerosol Federation   (Belgium)

^g Kings Buildings   (United Kingdom)

^h RESEARCH INSTITUTE FOR FRAGRANCE MATERIALS   (United States)

ⁱ L ORÉAL RECHERCHE   (France)

^j PROCTER AND GAMBLE COMPANY   (United States)

^k Formulation Development Services   (India)

more..

Author keywords

Exposure; Inhalation; Risk assessment; Spray

Indexed keywords

AMBIENT AIR; CHEMICAL SAFETY; DISPERSION; ENVIRONMENTAL FACTOR; EXPOSURE; HAZARD ASSESSMENT; HUMAN; MARKETING; PARTICLE SIZE; PRIORITY JOURNAL; PRODUCT SAFETY; RESPIRATORY SYSTEM; REVIEW; RISK ASSESSMENT; RISK MANAGEMENT;

EXPOSURE; INHALATION; RISK ASSESSMENT; SPRAY;

ADMINISTRATION, INHALATION; ADMINISTRATION, INTRANASAL; AEROSOLS; ANIMALS; CONSUMER PRODUCT SAFETY; EUROPEAN UNION; GERMANY; GUIDELINES AS TOPIC; HUMANS; LEGISLATION, DRUG; MODELS, BIOLOGICAL; NEBULIZERS AND VAPORIZERS; NO-OBSERVED-ADVERSE-EFFECT LEVEL; RISK ASSESSMENT; TOXICITY TESTS;

EID: 84897497122     PISSN: 03784274     EISSN: 18793169     Source Type: Journal    
DOI: 10.1016/j.toxlet.2014.03.005     Document Type: Review

References (33)

1. Barlow S., Renwick A.G., Kleiner J., Bridges J., Busk L., Dybing E., Edler L., Eisenbrand G., Fink-Gremmels J., Knaap A., Kroes R., Liem D., Muller D.J.G., Page S., Rolland V., Schlatter J., Tritscher A., Tueting W., Wurtzen G. Risk assessment of substances that are both genotoxic and carcinogenic. Report of an international conference. Food Chem. Toxicol. 2006, 44:1636-1650.
2. Bremmer H.J., Prud'homme de Lodder L.C.H., van Engelen J.G.M. Cosmetics Fact Sheet to Assess the Risk for the Consumer. Updated Version for ConsExpo 4, RIVM Report 320104001/2006 2006.
3. Bremmer H.J., Blom W.M., van Hoeven-Arentzen P.H., Prud'homme de Lodder L.C.H., van Raaij M.T.M., Straetmans E.H.F.M., van Veen M.P., van Engelen J.G.M. Pest Control Products Fact Sheet. To Assess the Risks for the Consumer. Updated Version for ConsExpo 4, RIVM Report 320005002/2006 2006.
4. British Aerosol Manufacturers' Association (BAMA) BAMA Indoor Air Model, Building Exposure Scenarios. Issue 1 2008.
5. Carthew P., Clapp C., Gutsell S. Exposure based waiving: the application of the toxicological threshold of concern (TTC) to inhalation exposure for aerosol ingredients in consumer products. Food Chem. Toxicol. 2009, 47:1287-1295.
6. Carthew P., Griffiths H., Keech S., Hartop P. Safety assessment for hairspray resins: risk assessment based on rodent inhalation studies. Inhal. Toxicol. 2002, 14:401-416.
7. Eickmann U. Methoden der Ermittlung und Bewertung chemischer Expositionen an Arbeitsplätzen. ecomed MEDIZIN 2007.
8. Eickmann U., Eickmann J., Tischer M. Exposure to sprays - comparison of the available exposure models. Gefahrstoffe - Reinhaltung der Luft 2007, 67(7/8):305-318.
9. European Aerosol Federation (FEA-Brussels) Guide on Particle Size Measurements from Aerosol Products 2009.
10. European Chemical Agency (ECHA) Guidance on Information Requirements and Chemical Safety Assessment. Chapter R.8: Characterisation of Dose [Concentration] - Response for Human Health 2012.
11. European Chemical Agency (ECHA) Guidance on Information Requirements and Chemical Safety Assessment. Chapter R.15: Consumer Exposure Estimation 2012.
12. European Commission and European Parliament Council of 18 December 2006 Concerning the Registration, Evaluation, Authorisation and Restriction of Chemicals. REACH Regulation, Official Journal L396 2006, 30/12/2006, (1907/2006/EC) 2006.
13. European Commission and European Parliament Council of 16 December 2008 on Classification, Labelling and Packaging of Substances and Mixtures. Official Journal L353 2008, 31/12/2008, (1272/2008/EC) 2008.
14. European Commission and European Parliament Council of 30 November 2009 on Cosmetic Products (recast). Official Journal L342 2009, 22/12/2009, (1223/2009/EC) 2009.
15. European Commission Council Directive of 20 May 1975 on the Approximation of the Laws of the Member States Relating to Aerosol Dispensers. Official Journal L147 1975, 09/06/1975, (75/324/EEC) 1975.
16. Garcia G.J., Kimbell J.S. Deposition of inhaled nanoparticles in the rat nasal passages: dose to the olfactory region. Inhal. Toxicol. 2009, 21(14):1165-1175.
17. Hall B., Tozer S., Safford B., Coroama M., Steiling W., Leneveu-Duchemin M.C., McNamara C., Gibney M. European consumer exposure to cosmetic products, a framework for conducting population exposure assessments. Food Chem. Toxicol. 2007, 45:2097-2108.
18. Koch W., Behnke W., Berger-Preiß E., Kock H., Gerling S., Hahn S., Schröder K. Validation of an EDP-assisted model for assessing inhalation exposure and dermal exposure during spraying processes. Research Project F2137 2012, BauA, Dortmund. 1st ed. Bundesanstalt für Arbeitsschutz und Arbeitsmedizin (Ed.).
19. Loretz L., Api A.M., Barraj L., Burdick J., Davis de A., Dressler W., Gilberti E., Jarrett G., Mann S., Laurie Pan Y.H., Re T., Renskers K., Scrafford C., Vater S. Exposure data for personal care products: hairspray, spray perfume, liquid foundation, shampoo, body wash, and solid antiperspirant. Food Chem. Toxicol. 2006, 44:2008-2018.
20. MAK Commission (Commission for the Investigation of Health Hazards of Chemical Compounds in the Work Area) List of MAK and BAT Values 2012: Maximum Concentrations and Biological Tolerance Values at the Workplace. Report 48 2012, Wiley-VCH, Weinheim, (German language Version: Senatskommission zur Prufung gesundheitsschädlicher Arbeitsstoffe, Mitteilung 48, MAK- und BAT-Werte-Liste 2012). Deutsche Forschungsgemeinschaft (DFG) (Ed.).
21. Martonen T.B., Schroeter J.D. Risk assessment dosimetry model for inhaled particulate matter: II. Laboratory surrogates (rat). Toxicol Lett. 2003, 138:133-142.
22. McNamara C., Rohan D., Golden D., Gibney M., Hall B., Tozer S., Safford B., Coroama M., Leneveu-Duchemin M.C., Steiling W. Probabilistic modeling of European consumer exposure to cosmetic products. Food Chem. Toxicol. 2007, 45:2086-2096.
23. RIVM General Fact Sheet Limiting Conditions and Reliability, Ventilation, Room Size, Body Surface Area. Updated Version for ConsExpo 4 2006.
24. Rothe H., Fautz R., Gerber E., Neumann L., Rettinger K., Schuh W., Gronewold C. Special aspects of cosmetic spray safety evaluations: principles on inhalation risk assessment. Toxicol. Lett. 2011, 205:97-104.
25. Salem H., Katz S.A. Inhalation Toxicology 2006, CRC Taylor & Francis, Boca Raton, USA, (ISBN-10: 0849340497). 2nd ed.
26. Schneider K., Schwarz M., Burkholder I., Kopp-Schneider A., Edler L., Kinsner-Ovaskainen A., Hartung T., Hoffmann S. "ToxRTool", a new tool to assess the reliability of toxicological data. Toxicol. Lett. 2009, 189:138-144.
27. Schroeter J.D. Toxicological highlight: the use of nasal dosimetry models in risk assessment of inhaled gases. Toxicol. Sci. 2009, 108:1-3.
28. Schroeter J.D., Kimbell J.S. Incorporation of tissue reaction kinetics in a computational fluid dynamics model for nasal extraction of inhaled hydrogen sulfide in rats. Toxicol. Sci. 2006, 90:198-207.
29. Schroeter J.D., Kimbell J.S. Use of a pharmacokinetic-driven computational fluid dynamics model to predict nasal extraction of hydrogen sulfide in rats and humans. Toxicol. Sci. 2006, 94:359-367.
30. Scientific Committee on Consumer Safety (SCCS) The SCCS's Notes of Guidance for the Testing of Cosmetic Substances and their Safety Evaluation. 8th Revision (SCCS/1501/12), 11 December 2012 2012.
31. Steiling W., Buttgereit P., Hall B., O'Keeffe L., Safford B., Tozer S., Coroama M. Skin exposure to deodorants/antiperspirants in aerosol form. Food Chem. Toxicol. 2012, 50:2206-2215.
32. US Environmental Protection Agency (US-EPA) Exposure Factors Handbook: 2011 Edition, EPA/600/R-09/052F 2011.
33. Weerdesteijn M.C.H., Bremmer H.J., Zeilmaker M.J., van Veen M.P. Hygienic Cleaning Products used in the Kitchen 1999, The Netherlands: National Institute for Public Health and Environment (RIVM), Bilthoven, (report no. 612810008).