메뉴 건너뛰기




Volumn 23, Issue 9, 2014, Pages 2498-2510

Gene-centric meta-analyses for central adiposity traits in up to 57 412 individuals of european descent confirm known loci and reveal several novel associations

(74)  Yoneyama, Sachiko a   Guo, Yiran c,d   Lanktree, Matthew B e   Barnes, Michael R g,h   Elbers, Clara C i   Karczewski, Konrad J j   Padmanabhan, Sandosh k   Bauer, Florianne i   Baumert, Jens l   Beitelshees, Amber m   Berenson, Gerald S n   Boer, Jolanda M A o   Burke, Gregory p   Cade, Brian q,r   Chen, Wei n   Cooper Dehoff, Rhonda M s   Gaunt, Tom R t   Gieger, Christian l   Gong, Yan s   Gorski, Mathias u,v   more..


Author keywords

[No Author keywords available]

Indexed keywords

3' UNTRANSLATED REGION; 5' UNTRANSLATED REGION; ADIPOSE TISSUE; ANTHROPOMETRY; ARTICLE; BODY FAT; CHROMOSOME 12; CHROMOSOME 15; CHROMOSOME 17; CHROMOSOME 3; COHORT ANALYSIS; DATA BASE; EUROPE; GENE EXPRESSION; GENE FREQUENCY; GENE LOCUS; GENETIC ASSOCIATION; GENETIC HETEROGENEITY; GENETIC TRAIT; GENOTYPE; GROUPS BY AGE; HEREDITY; HUMAN; INTRON; OBESITY; PHENOTYPE; PLEIOTROPY; POPULATION GENETIC PARAMETERS; PRIORITY JOURNAL; SEX DIFFERENCE; SINGLE NUCLEOTIDE POLYMORPHISM; WAIST HIP RATIO; ADULT; AGED; BODY MASS; CAUCASIAN; FEMALE; GENETICS; MALE; META ANALYSIS; MIDDLE AGED; VERY ELDERLY; WAIST CIRCUMFERENCE; YOUNG ADULT;

EID: 84897479338     PISSN: 09646906     EISSN: 14602083     Source Type: Journal    
DOI: 10.1093/hmg/ddt626     Document Type: Article
Times cited : (24)

References (68)
  • 1
    • 12344327669 scopus 로고    scopus 로고
    • Body mass index and mortality: a meta-analysis based on person-level data from twenty-six observational studies
    • McGee, D.L. (2005) Body mass index and mortality: a meta-analysis based on person-level data from twenty-six observational studies. Ann. Epidemiol., 15, 87-97.
    • (2005) Ann. Epidemiol , vol.15 , pp. 87-97
    • Mc Gee, D.L.1
  • 2
    • 38949108241 scopus 로고    scopus 로고
    • Body-mass index and incidence of cancer: a systematic review and meta-analysis of prospective observational studies
    • Renehan, A.G., Tyson, M., Egger, M., Heller, R.F. and Zwahlen, M. (2008) Body-mass index and incidence of cancer: a systematic review and meta-analysis of prospective observational studies. Lancet., 371, 569-578.
    • (2008) Lancet , vol.371 , pp. 569-578
    • Renehan, A.G.1    Tyson, M.2    Egger, M.3    Heller, R.F.4    Zwahlen, M.5
  • 3
    • 0003609309 scopus 로고    scopus 로고
    • World Health Organ
    • Obesity: preventing and managing the global epidemic. Report of a WHO consultation.
    • Obesity: preventing and managing the global epidemic. Report of a WHO consultation. (2000) World Health Organ. Tech. Rep. Ser., 894, 16-97.
    • (2000) Tech. Rep. Ser , vol.894 , pp. 16-97
  • 4
    • 53849092685 scopus 로고    scopus 로고
    • Will All Americans Become Overweight or Obese? Estimating the Progression and Cost of the US Obesity Epidemic
    • Wang, Y., Beydoun, M.A., Liang, L., Caballero, B. and Kumanyika, S.K. (2008) Will All Americans Become Overweight or Obese? Estimating the Progression and Cost of the US Obesity Epidemic. Obesity., 16, 2323-2330.
    • (2008) Obesity , vol.16 , pp. 2323-2330
    • Wang, Y.1    Beydoun, M.A.2    Liang, L.3    Caballero, B.4    Kumanyika, S.K.5
  • 6
    • 12344298435 scopus 로고    scopus 로고
    • Prognostic impact of body weight and abdominal obesity in women and men with cardiovascular disease
    • Dagenais, G.R., Yi, Q., Mann, J.F.E., Bosch, J., Pogue, J. and Yusuf, S. (2005) Prognostic impact of body weight and abdominal obesity in women and men with cardiovascular disease. Am. Heart J., 149, 54-60.
    • (2005) Am. Heart J , vol.149 , pp. 54-60
    • Dagenais, G.R.1    Yi, Q.2    Mann, J.F.E.3    Bosch, J.4    Pogue, J.5    Yusuf, S.6
  • 9
    • 84871394883 scopus 로고    scopus 로고
    • Body mass index vs cholesterol in cardiovascular disease risk prediction models
    • Faeh, D., Braun, J. and Bopp, M. (2012) Body mass index vs cholesterol in cardiovascular disease risk prediction models. Arch. Intern. Med., 172, 1766-1768.
    • (2012) Arch. Intern. Med , vol.172 , pp. 1766-1768
    • Faeh, D.1    Braun, J.2    Bopp, M.3
  • 11
    • 84861736693 scopus 로고    scopus 로고
    • Prediction of Cardiovascular Events with Consideration of General and Central Obesity Measures in Diabetic Adults: Results of the 8
    • Khalili, S., Hatami, M., Hadaegh, F., Sheikholeslami, F. and Azizi, F. (2012) Prediction of Cardiovascular Events with Consideration of General and Central Obesity Measures in Diabetic Adults: Results of the 8.4-Year Follow-Up. Metab. Syndr. Relat. Disord., 10, 218-224.
    • (2012) 4-Year Follow-Up. Metab. Syndr. Relat. Disord , vol.10 , pp. 218-224
    • Khalili, S.1    Hatami, M.2    Hadaegh, F.3    Sheikholeslami, F.4    Azizi, F.5
  • 12
    • 0034878336 scopus 로고    scopus 로고
    • Waist and hip circumferences have independent and opposite effects on cardiovascular disease risk factors: the Quebec Family Study
    • Seidell, J.C., Pérusse, L., Després, J.-P. and Bouchard, C. (2001) Waist and hip circumferences have independent and opposite effects on cardiovascular disease risk factors: the Quebec Family Study. Am. J. Clin. Nutr., 74, 315-321.
    • (2001) Am. J. Clin. Nutr , vol.74 , pp. 315-321
    • Seidell, J.C.1    Pérusse, L.2    Després, J.-P.3    Bouchard, C.4
  • 16
    • 33845886915 scopus 로고    scopus 로고
    • Abdominal obesity and metabolic syndrome
    • Després, J.-P. and Lemieux, I. (2006) Abdominal obesity and metabolic syndrome. Nature., 444, 881-887.
    • (2006) Nature , vol.444 , pp. 881-887
    • Després, J.-P.1    Lemieux, I.2
  • 17
    • 84856263295 scopus 로고    scopus 로고
    • Visceral obesity, metabolic syndrome, insulin resistance and cancer
    • Doyle, S.L., Donohoe, C.L., Lysaght, J. and Reynolds, J.V. (2012) Visceral obesity, metabolic syndrome, insulin resistance and cancer. Proc. Nutr. Soc., 71, 181-189.
    • (2012) Proc. Nutr. Soc , vol.71 , pp. 181-189
    • Doyle, S.L.1    Donohoe, C.L.2    Lysaght, J.3    Reynolds, J.V.4
  • 18
    • 0002017482 scopus 로고
    • The heritability of certain anthropometric characters as ascertained from measurements of twins
    • Clark, P.J. (1956) The heritability of certain anthropometric characters as ascertained from measurements of twins. Am. J. Hum. Gen., 8, 49-54.
    • (1956) Am. J. Hum. Gen , vol.8 , pp. 49-54
    • Clark, P.J.1
  • 19
    • 0030843960 scopus 로고    scopus 로고
    • Genetic and environmental factors in relative body weight and human adiposity
    • Maes, H.H., Neale, M.C. and Eaves, L.J. (1997) Genetic and environmental factors in relative body weight and human adiposity. Behav. Genet., 27, 325-351.
    • (1997) Behav. Genet , vol.27 , pp. 325-351
    • Maes, H.H.1    Neale, M.C.2    Eaves, L.J.3
  • 20
    • 0032198565 scopus 로고    scopus 로고
    • Genetic and behavioral determinants of waist-hip ratio and waist circumference in women twins
    • Rose, K.M., Newman, B., Mayer-Davis, E.J. and Selby, J.V. (1998) Genetic and behavioral determinants of waist-hip ratio and waist circumference in women twins. Obes. Res., 6, 383-392.
    • (1998) Obes. Res , vol.6 , pp. 383-392
    • Rose, K.M.1    Newman, B.2    Mayer-Davis, E.J.3    Selby, J.V.4
  • 27
    • 38949107361 scopus 로고    scopus 로고
    • Obesity-still highly heritable after all these years
    • Musani, S.K., Erickson, S. and Allison, D.B. (2008) Obesity-still highly heritable after all these years. Am. J. Clin. Nutr., 87, 275-276.
    • (2008) Am. J. Clin. Nutr , vol.87 , pp. 275-276
    • Musani, S.K.1    Erickson, S.2    Allison, D.B.3
  • 30
    • 50549083074 scopus 로고    scopus 로고
    • Curses-winner's and otherwise-in genetic epidemiology
    • Kraft, P. (2008)Curses-winner's, otherwise-in genetic epidemiology. Epidemiology., 19, 649-651.
    • (2008) Epidemiology , vol.19 , pp. 649-651
    • Kraft, P.1
  • 34
    • 84858779229 scopus 로고    scopus 로고
    • HaploReg: a resource for exploring chromatin states, conservation, and regulatory motif alterations within sets of genetically linked variants
    • Ward, L.D. and Kellis, M. (2012) HaploReg: a resource for exploring chromatin states, conservation, and regulatory motif alterations within sets of genetically linked variants. Nucleic Acids Res., 40, D930-D934.
    • (2012) Nucleic Acids Res , vol.40
    • Ward, L.D.1    Kellis, M.2
  • 38
    • 21344463761 scopus 로고    scopus 로고
    • Endocrine pancreatic tissue plasticity in obese humans is associated with cytoplasmic expression of PBX-1 in pancreatic ductal cells
    • Muharram, G., Beucher, A., Moerman, E., Belaïch, S., Gmyr, V., Vandewalle, B., Pattou, F. and Kerr-Conte, J. (2005) Endocrine pancreatic tissue plasticity in obese humans is associated with cytoplasmic expression of PBX-1 in pancreatic ductal cells. Biochem. Biophys. Res. Commun., 333, 1153-1159.
    • (2005) Biochem. Biophys. Res. Commun , vol.333 , pp. 1153-1159
    • Muharram, G.1    Beucher, A.2    Moerman, E.3    Belaïch, S.4    Gmyr, V.5    Vandewalle, B.6    Pattou, F.7    Kerr-Conte, J.8
  • 39
    • 0036544854 scopus 로고    scopus 로고
    • Pbx1 inactivation disrupts pancreas development and in Ipf1-deficient mice promotes diabetes mellitus
    • Kim, S.K., Selleri, L., Lee, J.S., Zhang, A.Y., Gu, X., Jacobs, Y. and Cleary, M.L. (2002) Pbx1 inactivation disrupts pancreas development and in Ipf1-deficient mice promotes diabetes mellitus. Nat. Genet., 30, 430-435.
    • (2002) Nat. Genet , vol.30 , pp. 430-435
    • Kim, S.K.1    Selleri, L.2    Lee, J.S.3    Zhang, A.Y.4    Gu, X.5    Jacobs, Y.6    Cleary, M.L.7
  • 44
  • 46
    • 0033599030 scopus 로고    scopus 로고
    • An inhibitory switch derepressed by pbx, hox, and Meis/Prep1 partners regulates DNA-binding by pbx1 and E2a-pbx1 and is dispensable for myeloid immortalization by E2a-pbx1
    • Calvo, K.R., Knoepfler, P., Mc Grath, S. and Kamps, M.P. (1999) An inhibitory switch derepressed by pbx, hox, and Meis/Prep1 partners regulates DNA-binding by pbx1 and E2a-pbx1 and is dispensable for myeloid immortalization by E2a-pbx1. Oncogene., 18, 8033-8043.
    • (1999) Oncogene , vol.18 , pp. 8033-8043
    • Calvo, K.R.1    Knoepfler, P.2    Mc Grath, S.3    Kamps, M.P.4
  • 47
    • 84874772792 scopus 로고    scopus 로고
    • The amidation step of diphthamide biosynthesis in yeast requires DPH6, a gene identified through mining the DPH1-DPH5 interaction network
    • Uthman, S., Bär, C., Scheidt, V., Liu, S., ten Have, S., Giorgini, F., Stark, M.J.R. and Schaffrath, R. (2013) The amidation step of diphthamide biosynthesis in yeast requires DPH6, a gene identified through mining the DPH1-DPH5 interaction network. PLoS Genet., 9, e1003334.
    • (2013) PLoS Genet , vol.9
    • Uthman, S.1    Bär, C.2    Scheidt, V.3    Liu, S.4    ten Have, S.5    Giorgini, F.6    Stark, M.J.R.7    Schaffrath, R.8
  • 48
    • 34548504316 scopus 로고    scopus 로고
    • Fatty acid amide hydrolase: from characterization to therapeutics
    • Labar, G. and Michaux, C. (2007) Fatty acid amide hydrolase: from characterization to therapeutics. Chem. Biodivers., 4, 1882-1902.
    • (2007) Chem. Biodivers , vol.4 , pp. 1882-1902
    • Labar, G.1    Michaux, C.2
  • 49
    • 84857531280 scopus 로고    scopus 로고
    • Combining global and local measures for structure-based druggability predictions
    • Volkamer, A., Kuhn, D., Grombacher, T., Rippmann, F. and Rarey, M. (2012) Combining global and local measures for structure-based druggability predictions. J. Chem. Inf. Model., 52, 360-372.
    • (2012) J. Chem. Inf. Model , vol.52 , pp. 360-372
    • Volkamer, A.1    Kuhn, D.2    Grombacher, T.3    Rippmann, F.4    Rarey, M.5
  • 50
    • 77954575279 scopus 로고    scopus 로고
    • Impaired de novo choline synthesis explains why phosphatidylethanolamine N-methyltransferase-deficient mice are protected from diet-induced obesity
    • Jacobs, R.L., Zhao, Y., Koonen, D.P.Y., Sletten, T., Su, B., Lingrell, S., Cao, G., Peake, D.A., Kuo, M.-S., Proctor, S.D. et al. (2010) Impaired de novo choline synthesis explains why phosphatidylethanolamine N-methyltransferase-deficient mice are protected from diet-induced obesity. J. Biol. Chem., 285, 22403-22413.
    • (2010) J. Biol. Chem , vol.285 , pp. 22403-22413
    • Jacobs, R.L.1    Zhao, Y.2    Koonen, D.P.Y.3    Sletten, T.4    Su, B.5    Lingrell, S.6    Cao, G.7    Peake, D.A.8    Kuo, M.-S.9    Proctor, S.D.10
  • 54
    • 84871223778 scopus 로고    scopus 로고
    • Gene-centric meta-analyses of 108 912 individuals confirm known body mass index loci and reveal three novel signals
    • Guo, Y., Lanktree, M.B., Taylor, K.C., Hakonarson, H., Lange, L.A. and Keating, B.J. (2013) Gene-centric meta-analyses of 108 912 individuals confirm known body mass index loci and reveal three novel signals. Hum. Mol. Genet., 22, 184-201.
    • (2013) Hum. Mol. Genet , vol.22 , pp. 184-201
    • Guo, Y.1    Lanktree, M.B.2    Taylor, K.C.3    Hakonarson, H.4    Lange, L.A.5    Keating, B.J.6
  • 55
    • 78649508578 scopus 로고    scopus 로고
    • MaCH: using sequence and genotype data to estimate haplotypes and unobserved genotypes
    • Li, Y., Willer, C.J., Ding, J., Scheet, P. and Abecasis, G.R. (2010) MaCH: using sequence and genotype data to estimate haplotypes and unobserved genotypes. Genet. Epidemiol., 34, 816-834.
    • (2010) Genet. Epidemiol , vol.34 , pp. 816-834
    • Li, Y.1    Willer, C.J.2    Ding, J.3    Scheet, P.4    Abecasis, G.R.5
  • 57
    • 77955894071 scopus 로고    scopus 로고
    • METAL: fast and efficient meta-analysis of genomewide association scans
    • Willer, C.J., Li, Y. and Abecasis, G.R. (2010) METAL: fast and efficient meta-analysis of genomewide association scans. Bioinformatics., 26, 2190-2191.
    • (2010) Bioinformatics , vol.26 , pp. 2190-2191
    • Willer, C.J.1    Li, Y.2    Abecasis, G.R.3
  • 58
    • 0037098199 scopus 로고    scopus 로고
    • Quantifying heterogeneity in a meta-analysis
    • Higgins, J.P.T. and Thompson, S.G. (2002) Quantifying heterogeneity in a meta-analysis. Stat. Med., 21, 1539-1558.
    • (2002) Stat. Med , vol.21 , pp. 1539-1558
    • Higgins, J.P.T.1    Thompson, S.G.2
  • 59
    • 78649505227 scopus 로고    scopus 로고
    • Meta-analysis of sexspecific genome-wide association studies
    • Magi, R., Lindgren, C.M. and Morris, A.P. (2010) Meta-analysis of sexspecific genome-wide association studies. Genet. Epidemiol., 34, 846-853.
    • (2010) Genet. Epidemiol , vol.34 , pp. 846-853
    • Magi, R.1    Lindgren, C.M.2    Morris, A.P.3
  • 65
    • 77956534324 scopus 로고    scopus 로고
    • ANNOVAR: functional annotation of genetic variants from high-throughput sequencing data
    • Wang, K., Li, M. and Hakonarson, H. (2010) ANNOVAR: functional annotation of genetic variants from high-throughput sequencing data. Nucleic Acids Res., 38, e164.
    • (2010) Nucleic Acids Res , vol.38
    • Wang, K.1    Li, M.2    Hakonarson, H.3
  • 67
    • 29144531173 scopus 로고    scopus 로고
    • The druggable genome: an update
    • Russ, A.P. and Lampel, S. (2005) The druggable genome: an update. Drug Discov. Today., 10, 1607-1610.
    • (2005) Drug Discov. Today , vol.10 , pp. 1607-1610
    • Russ, A.P.1    Lampel, S.2
  • 68
    • 78651467817 scopus 로고    scopus 로고
    • A machine learning approach for genome-wide prediction of morbid and druggable humangenes based on systems-level data
    • Costa, P.R., Acencio, M.L. and Lemke, N. (2010) A machine learning approach for genome-wide prediction of morbid and druggable humangenes based on systems-level data. BMC Genomics., 11, S5-S9.
    • (2010) BMC Genomics , vol.11
    • Costa, P.R.1    Acencio, M.L.2    Lemke, N.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.