Thermodynamic investigation of Z33-antibody interaction leads to selective purification of human antibodies

Journal of Biotechnology

Volumn 179, Issue 1, 2014, Pages 32-41

  van Eldijk, Mark B ^a,b   Smits, Ferdinanda C M ^a   Thies, Jens C ^c   Mecinović, Jasmin ^a   Van Hest, Jan C M ^a  

^a RADBOUD UNIVERSITY NIJMEGEN   (Netherlands)

^b DUTCH POLYMER INSTITUTE DPI   (Netherlands)

^c DSM RESEARCH   (Netherlands)

Author keywords

Antibody purification; Elastin like polypeptides; Isothermal titration calorimetry; Protein A; Protein engineering

Indexed keywords

AMINO ACIDS; BACTERIA; BINDING ENERGY; CALORIMETERS; CALORIMETRY; CHEMICAL DETECTION; ISOTHERMS; MAMMALS; PEPTIDES; POLYPEPTIDES; PURIFICATION; TITRATION;

ANTIBODY PURIFICATION; ELASTIN-LIKE POLYPEPTIDES; ISOTHERMAL TITRATION CALORIMETRY; PROTEIN A; PROTEIN ENGINEERING;

ANTIBODIES;

AMINO ACID; ANTIBODY; ELASTIN; HYBRID PROTEIN; IMMUNOGLOBULIN G; POLYPEPTIDE; PROTEIN A; PROTEIN ANTIBODY; STAPHYLOCOCCUS PROTEIN A;

AMINO ACID SEQUENCE; ANTIGEN BINDING; ARTICLE; BINDING AFFINITY; DRUG PROTEIN BINDING; ENTHALPY; GEL PERMEATION CHROMATOGRAPHY; HUMAN; ISOTHERMAL TITRATION CALORIMETRY; NONHUMAN; PRECIPITATION; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN ENGINEERING; PURIFICATION; STIMULUS RESPONSE; THERMODYNAMICS; ANIMAL; BINDING SITE; BOVINAE; CHEMICAL STRUCTURE; CHEMISTRY; IMMUNOLOGY; METABOLISM;

ANIMALS; BINDING SITES; CATTLE; ELASTIN; HUMANS; IMMUNOGLOBULIN G; MODELS, MOLECULAR; RECOMBINANT FUSION PROTEINS; STAPHYLOCOCCAL PROTEIN A; THERMODYNAMICS;

EID: 84897471366     PISSN: 01681656     EISSN: 18734863     Source Type: Journal    
DOI: 10.1016/j.jbiotec.2014.03.023     Document Type: Article

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