Influence of neighboring groups on the thermodynamics of hydrophobic binding: An added complex facet to the hydrophobic effect

Journal of Medicinal Chemistry

Volumn 57, Issue 6, 2014, Pages 2315-2333

  Nasief, Nader N ^a   Hangauer, David ^a  

^a UNIVERSITY AT BUFFALO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CARBOXYLIC ACID; ENZYME INHIBITOR; THERMOLYSIN PHOSPHONAMIDATE INHIBITOR; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; CHEMICAL MODIFICATION; COMPLEX FORMATION; CRYSTAL STRUCTURE; ENTHALPY; ENTROPY; HYDRATION; HYDROPHOBICITY; ISOTHERMAL TITRATION CALORIMETRY; LIGAND BINDING; MOLECULAR RECOGNITION; SUBSTITUTION REACTION; THERMODYNAMICS;

BINDING SITES; CALORIMETRY; CRYSTALLOGRAPHY, X-RAY; ENTROPY; HYDROGEN BONDING; INDICATORS AND REAGENTS; LIGANDS; MODELS, MOLECULAR; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; THERMODYNAMICS;

EID: 84897471228     PISSN: 00222623     EISSN: 15204804     Source Type: Journal    
DOI: 10.1021/jm401609a     Document Type: Article

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