Transposon mutagenesis of probiotic Lactobacillus casei identifies asnH, an asparagine synthetase gene involved in its immune-activating capacity

PLoS ONE

Volumn 9, Issue 1, 2014, Pages

  Ito, Masahiro ^a   Kim, Yun Gi ^a   Tsuji, Hirokazu ^b   Takahashi, Takuya ^b   Kiwaki, Mayumi ^b   Nomoto, Koji ^b   Danbara, Hirofumi ^a   Okada, Nobuhiko ^a  

^a KITASATO UNIVERSITY   (Japan)

^b YAKULT CENTRAL INSTITUTE FOR MICROBIOLOGICAL RESEARCH   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ASPARTATE AMMONIA LIGASE; CHAPERONE; LYSOZYME; PEPTIDOGLYCAN; PROTEIN DNAJ; PROTEIN DNAK;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; ASNH GENE; BACTERIAL GROWTH; BACTERIAL STRAIN; BACTERIOPHAGE; BIOSYNTHESIS; CONTROLLED STUDY; DNA SEQUENCE; DNAJ GENE; DNAK GENE; ENZYME ACTIVITY; ENZYME LINKED IMMUNOSORBENT ASSAY; GENE IDENTIFICATION; GENE MUTATION; GENE SEQUENCE; IN VIVO STUDY; INNATE IMMUNITY; LACTOBACILLUS CASEI; LISTERIOSIS; MALE; MOLECULAR CLONING; MOUSE; MUTAGENESIS; MUTANT; NONHUMAN; NUCLEOTIDE SEQUENCE; PLASMID; PROTEIN EXPRESSION; PROTEIN PURIFICATION; TRANSMISSION ELECTRON MICROSCOPY; TRANSPOSON; WILD TYPE;

AMINO ACID SEQUENCE; ANIMALS; ASPARTATE-AMMONIA LIGASE; BACTERIAL PROTEINS; BACTERIOPHAGES; CELL WALL; CYTOKINES; DISACCHARIDES; DNA TRANSPOSABLE ELEMENTS; GENES, BACTERIAL; IMMUNITY; LACTOBACILLUS CASEI; LISTERIOSIS; METHYLNITRONITROSOGUANIDINE; MICE; MOLECULAR SEQUENCE DATA; MUTAGENESIS, INSERTIONAL; MUTATION; PEPTIDOGLYCAN; PROBIOTICS; SEQUENCE ALIGNMENT; SPLEEN;

EID: 84897445631     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0083876     Document Type: Article

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