D-ribosylation induces cognitive impairment through RAGE-dependent astrocytic inflammation

Cell Death and Disease

Volumn 5, Issue 3, 2014, Pages

  Han, C ^a   Lu, Y ^a,b   Wei, Y ^a   Wu, B ^a,c   Liu, Y ^a   He, R ^a,d  

^a INSTITUTE OF BIOPHYSICS   (China)

^b UNIVERSITY OF SCIENCE AND TECHNOLOGY OF CHINA   (China)

^c UNIVERSITY OF CHINESE ACADEMY OF SCIENCES   (China)

^d INSTITUTE OF PSYCHOLOGY   (China)

Author keywords

Advanced glycation end products; Astrocyte activation; D ribose; Inflammatory response; RAGE; Type 2 diabetes mellitus

Indexed keywords

ADVANCED GLYCATION END PRODUCT; ADVANCED GLYCATION END PRODUCT RECEPTOR; GLIAL FIBRILLARY ACIDIC PROTEIN; GLUCOSE; RIBOSE; TRANSCRIPTION FACTOR RELA; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASTROCYTE; ASTROCYTOMA CELL; CELL ACTIVATION; COGNITIVE DEFECT; CONTROLLED STUDY; DIABETES MELLITUS; DIABETIC PATIENT; GLYCATION; HIPPOCAMPUS; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; INFLAMMATION; MEMORY; MORRIS WATER MAZE TEST; MOUSE; NEUROBLASTOMA CELL; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN GLYCOSYLATION; PROTEIN MODIFICATION; PROTEIN PROCESSING; SIGNAL TRANSDUCTION; SPATIAL LEARNING; WESTERN BLOTTING;

ANIMALS; ASTROCYTES; BEHAVIOR, ANIMAL; CELL LINE, TUMOR; COGNITION; COGNITION DISORDERS; DIABETES COMPLICATIONS; ENCEPHALITIS; GLIAL FIBRILLARY ACIDIC PROTEIN; GLYCOSYLATION; GLYCOSYLATION END PRODUCTS, ADVANCED; HIPPOCAMPUS; HUMANS; INFLAMMATION MEDIATORS; MALE; MAZE LEARNING; MEMORY; MICE; MICE, INBRED C57BL; NF-KAPPA B; PROTEIN PROCESSING, POST-TRANSLATIONAL; REACTION TIME; RECEPTORS, IMMUNOLOGIC; RIBOSE; RNA INTERFERENCE; TIME FACTORS; TRANSFECTION; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84897433472     PISSN: None     EISSN: 20414889     Source Type: Journal    
DOI: 10.1038/cddis.2014.89     Document Type: Article

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