Increased glutamate levels in the vitreous of patients with retinal detachment

Experimental Eye Research

Volumn 83, Issue 1, 2006, Pages 45-50

  Diederen, Roselie M H ^a   La Heij, Ellen C ^a   Deutz, Nicolaas E P ^b   Kijlstra, Aize ^a   Kessels, Alfons G H ^a   van Eijk, Hans M H ^b   Liem, Albert T A ^a   Dieudonné, Suzanne ^a   Hendrikse, Fred ^a  

^a MAASTRICHT UNIVERSITY MEDICAL CENTER   (Netherlands)

^b MAASTRICHT UNIVERSITY   (Netherlands)

Author keywords

amino acid; excitotoxicity; glutamate; retinal detachment; vitreous

Indexed keywords

4 AMINOBUTYRIC ACID; AMINO ACID RECEPTOR AFFECTING AGENT; ASPARTIC ACID; GLUTAMIC ACID; GLYCINE; TAURINE;

ADULT; AGED; ARTICLE; CILIARY DISK; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; CORRELATION ANALYSIS; DIABETIC RETINOPATHY; EPIRETINAL MEMBRANE; FEMALE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; MAJOR CLINICAL STUDY; MALE; MULTIVARIATE ANALYSIS; OUTCOME ASSESSMENT; POSTOPERATIVE PERIOD; PRIORITY JOURNAL; RETINA DETACHMENT; STATISTICAL SIGNIFICANCE; VISUAL ACUITY; VITRECTOMY; VITREOUS BODY;

ASPARTIC ACID; FEMALE; GABA AGENTS; GAMMA-AMINOBUTYRIC ACID; GLUTAMIC ACID; GLYCINE; HUMANS; MALE; MIDDLE AGED; NEUROTRANSMITTER AGENTS; RETINAL DETACHMENT; RETROSPECTIVE STUDIES; TAURINE; VISUAL ACUITY; VITRECTOMY; VITREOUS BODY;

EID: 33646879614     PISSN: 00144835     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.exer.2005.10.031     Document Type: Article

References (24)

1. Ambati J., Chalam K.V., Chawla D.K., D'Angio C.T., Guillet E.G., Rose J.S., et al. Elevated γ-aminobutyric acid, glutamate and vascular endothelial growth factor levels in the vitreous of patients with proliferative diabetic retinopathy. Arch. Ophthalmol. 115 (1997) 1161-1166
2. Asensio Sanchez V.M., Corral Azor A., Aguirre Aragon B., and De Paz Garcia M. Amino acid concentrations in the vitreous body in control subjects. Arch. Soc. Esp. 77 (2002) 611-616
3. Barnstable C.J. Glutamate and GABA in retinal circuitry. Curr. Opin. Neurobiol. 3 (1993) 520-525
4. Dawson V.L., and Dawson T.M. Nitric oxide neurotoxicity. J. Chem. Neuroanat. 10 3-4 (1996) 179-190
5. Dreyer E.B., Zurakowski D., Schumer R.A., Podos S.M., and Lipton S.A. Elevated glutamate levels in the vitreous body of humans and monkeys with glaucoma. Arch. Ophthalmol. 114 (1996) 299-305
6. Ferris F.L., Kassoff A., Bresnick G.H., and Bailey I. New visual acuity charts for clinical research. Am. J. Ophthalmol. 94 (1982) 91-96
7. Harada T., Harada C., Watanabe M., Inoue Y., Sakagawa T., Nakayama N., et al. Functions of the two glutamate transporters GLAST and GLT-1 in the retina. Proc. Natl Acad. Sci. U.S.A. 95 8 (1998) 4663-4666
8. Hochberg Y. A sharper Bonferroni procedure for multiple tests of significance. Biometrika 75 (1988) 800-802
9. Honkanen R.A., Baruah S., Zimmerman M.B., Khanna C.L., Weaver Y.K., Narkiewicz J., et al. Vitreous amino acid concentrations in patients with glaucoma undergoing vitrectomy. Arch. Ophthalmol. 121 (2003) 183-188
10. La Heij E.C., Hendrikse F., and Kessels A.G.H. Results and complications of temporary silicone oil tamponade in patients with complicated retinal detachments. Retina 21 (2001) 107-114
11. La Heij E.C., Van den Waarenburg M.P.H., Blaauwgeers H.G.T., Theunissen C., Kessels A., Liem A.T.A., Steinbusch H., and Hendrikse F. Levels of basic fibroblast growth factor (b-FGF), glutamine synthetase (GS), and interleukin-6 (IL-6) in vitreous fluid from patients with proliferative vitreoretinopathy (PVR). Am. J. Ophthalmol. 134 (2002) 367-375
12. Lewis G.P., Erickson P.A., Guèrin C.J., Anderson D.H., and Fisher S.K. Changes in the expression of specific Müller cell proteins during long-term retinal detachment. Exp. Eye Res. 49 (1989) 93-111
13. Lipton S.A. Failures and successes of NMDA receptor antagonists: molecular basis for the use of open-channel blockers like memantine in the treatment of acute and chronic neurologic insults. Neurorx 1 1 (2004 Jan) 101-110
14. Luo X., Heidinger V., Picaud S., Lambrou G., Drefus H., Sehel J., and Hicks D. Selective excitotoxic degeneration of adult pig retinal ganglion cells in vitro. Investig. Ophthalmol. Vis. Sci. 42 5 (2001) 1096-1106
15. Marc R.E., Murry R.F., and Basinger S.F. Pattern recognition of amino acid signatures in retinal neurons. J. Neurosci. 15 (1995) 5106-5129
16. Marc R.E., Murry R.F., Fisher S.K., Linberg K.A., and Lewis P.G. Amino acid signature in the detached cat retina. Investig. Ophthalmol. Vis. Sci. 39 (1998) 1694-1702
17. Mosinger J.L., Price M.T., Bai H.Y., Xiao H., Wozniak D.F., and Olney J.W. Blockage of both NMDA and non-NMDA receptors is required for optimal protection against ischemic neuronal degeneration in the in vivo adult mammalian retina. Exp. Neurol. 113 (1990) 10-17
18. Napper G.A., and Kalloniatis M. Neurochemical changes following postmortem ischemia in the rat retina. Vis. Neurosci. 16 (1999) 1169-1180
19. Napper G.A., Pianta M.J., and Kalloniatis M. Localization of amino acid neurotransmitters following in vitro ischemia and anoxia in the rat retina. Vis. Neurosci. 18 (2001) 413-427
20. Osborne N.N., and Herrera A.J. The effect of experimental ischaemia and excitatory amino acid agonists on the GABA and serotonin immunoreactivities in the rabbit retina. Neurosciences 59 (1994) 1071-1081
21. Sherry D.M., and Townes-Anderson E. Rapid glutaminergic alterations in the neural retina induced by retinal detachment. Investig. Ophthalmol. Vis. Sci. 41 (2000) 2779-2790
22. Van Eijk H.M.H., Rooyakkers D.R., and Deutz N.E.P. Rapid routine determination of amino acids in plasma by high-performance liquid chromatography with a 2-3 μm Spherisorb ODS II column. J. Chromatogr. 620 (1993) 143-148
23. Vorwerk C.K., Lipton S.A., Zurakowski D., Hyman B.T., Sabel B.A., and Dreyer E.B. Chronic low-dose glutamate is toxic to retinal ganglion cells: toxicity blocked by memantine. Investig. Ophthalmol. Vis. Sci. 37 (1996) 1618-1624
24. Yoon Y.H., and Marmor M.F. Dextromethorphan protects retina against ischemic injury in vivo. Arch. Ophthalmol. 107 (1989) 409-411