Decarboxylative fluorination strategies for accessing medicinally-relevant products

Current Topics in Medicinal Chemistry

Volumn 14, Issue 7, 2014, Pages 966-978

  Qiao, Yupu ^a   Zhu, Lingui ^a   Ambler, Brett R ^a   Altman, Ryan A ^a  

^a UNIVERSITY OF KANSAS   (United States)

Author keywords

Copper; Decarboxylation; Difluoromethylation; Fluorination; Trifluoromethylation

Indexed keywords

3,3 DIFLUOROIODOCYCLOPROPENE; 4,5 DIFLUOROMETHANOPROLINE; ALLYLIC BROMODIFLUOROACETATE; ALLYLIC DIFLUOROMETHANE; ALLYLIC DIFLUOROMETHYLSULFONE; ARYL TRIFLUOROMETHYL KETONE; BENZYLIC HALODIFLUOROACETATE; CHLORODIFLUOROACETIC ESTER; CYCLOHEXANONE; DIFLUOROCYCLOPROOPANE; DIFLUOROCYCLOPROPANE; DIFLUOROMETHYLENE PHOSPHONIUM; DIFLUOROMETHYLENEYLIDE; DIFLUOROMETHYLSULFONE; DIFLUORONORCARANE; DIMETHYL SULFOXIDE; FLUORINE 18; FLUORINE DERIVATIVE; FLUOROFORM; HAODIFLUOROACETATE ESTER; L, L DIFLUOROOLEFIN; N FLUOROBENZENESULFONIMIDE; PROPARGYLIC CHLORODIFLUOROACETATE; THIOPHENOL; TRIFLUOROACETIC ACID; TRIFLUOROACETOPHENONE; TRIFLUOROETHYLKETONE; TRIFLUOROMETHYLALLENE; TRIMETHYLSILYL FLUOROSULFONYLDIFLUOROACETATE; UNCLASSIFIED DRUG; UNINDEXED DRUG;

CYCLOPROPANATION; DECARBOXYLATION; DIFLUOROOLEFINATION; FLUORINATION; MEDICAL RESEARCH; OLEFINATION; POSITRON EMISSION TOMOGRAPHY; REACTION TIME; REVIEW; TAUTOMERIZATION; TRIFLUOROMETHYLATION;

ANIMALS; CARBOXYLIC ACIDS; CHEMISTRY, PHARMACEUTICAL; DECARBOXYLATION; HALOGENATION; HUMANS; HYDROCARBONS, FLUORINATED;

EID: 84897408697     PISSN: 15680266     EISSN: 18734294     Source Type: Journal    
DOI: 10.2174/1568026614666140202210850     Document Type: Review

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