TRAF5 and TRAF3IP2 gene polymorphisms are associated with Behçet's disease and Vogt-Koyanagi-Harada syndrome: A case-control study

PLoS ONE

Volumn 9, Issue 1, 2014, Pages

  Xiang, Qin ^a   Chen, Lu ^a   Hou, Shengping ^a   Fang, Jing ^a   Zhou, Yan ^a   Bai, Lin ^a   Liu, Yunjia ^a   Kijlstra, Aize ^b   Yang, Peizeng ^a  

^a CHONGQING MEDICAL UNIVERSITY   (China)

^b MAASTRICHT UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

DNA; INTERLEUKIN 6; INTERLEUKIN 8; LIPOPOLYSACCHARIDE; MESSENGER RNA; TUMOR NECROSIS FACTOR ALPHA; TUMOR NECROSIS FACTOR RECEPTOR ASSOCIATED FACTOR 5;

ARTICLE; BEHCET DISEASE; BLOOD SAMPLING; CASE CONTROL STUDY; CHINESE; CONTROLLED STUDY; DNA POLYMORPHISM; ENZYME LINKED IMMUNOSORBENT ASSAY; GENE EXPRESSION; GENETIC ASSOCIATION; GENOTYPE; HUMAN; MAJOR CLINICAL STUDY; PATHOGENESIS; POLYMERASE CHAIN REACTION; RESTRICTION FRAGMENT LENGTH POLYMORPHISM; SINGLE NUCLEOTIDE POLYMORPHISM; TRAF3IP2 GENE; TRAF5 GENE; VOGT KOYANAGI SYNDROME;

BEHCET SYNDROME; CASE-CONTROL STUDIES; CYTOKINES; GENE EXPRESSION REGULATION; GENETIC ASSOCIATION STUDIES; GENETIC PREDISPOSITION TO DISEASE; HUMANS; INFLAMMATION; LIPOPOLYSACCHARIDES; POLYMORPHISM, SINGLE NUCLEOTIDE; RNA, MESSENGER; TNF RECEPTOR-ASSOCIATED FACTOR 5; TUMOR NECROSIS FACTOR RECEPTOR-ASSOCIATED PEPTIDES AND PROTEINS; UVEOMENINGOENCEPHALITIC SYNDROME;

EID: 84897403547     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0084214     Document Type: Article

References (56)

1. Yang P, Fang W, Meng Q, Ren Y, Xing L, et al. (2008) Clinical features of Chinese patients with Behçet's disease. Ophthalmology 115: 312-318. e314.
2. Yang P, Ren Y, Li B, Fang W, Meng Q, et al. (2007) Clinical characteristics of Vogt-Koyanagi-Harada syndrome in Chinese patients. Ophthalmology 114: 606-614. e603.
3. Zhang Z, Peng J, Hou X, Dong Y (2006) Clinical manifestations of Behcet's disease in Chinese patients. APLAR Journal of Rheumatology 9: 244-247. (Pubitemid 44473294)
4. Ideguchi H, Suda A, Takeno M, Ueda A, Ohno S, et al. (2011) Behcet disease: evolution of clinical manifestations. Medicine (Baltimore) 90: 125-132.
5. Keino H, Okada AA (2007) Behcet's disease: global epidemiology of an Old Silk Road disease. Br J Ophthalmol 91: 1573-1574. (Pubitemid 350207369)
6. Meguro A, Inoko H, Ota M, Katsuyama Y, Oka A, et al. (2010) Genetics of Behçet disease inside and outside the MHC. Annals of the rheumatic diseases 69: 747-754.
7. Chen F, Hou S, Jiang Z, Chen Y, Kijlstra A, et al. (2012) CD40 gene polymorphisms confer risk of Behcet's disease but not of Vogt-Koyanagi-Harada syndrome in a Han Chinese population. Rheumatology (Oxford) 51: 47-51.
8. Hou S, Yang Z, Du L, Jiang Z, Shu Q, et al. (2012) Genome-wide association study identifies susceptible locus in STAT4 for Behcet's disease in Han Chinese. Arthritis Rheum.
9. Hu K, Hou S, Jiang Z, Kijlstra A, Yang P (2012) JAK2 and STAT3 polymorphisms in a Han Chinese population with Behcet's disease. Invest Ophthalmol Vis Sci 53: 538-541.
10. Read RW, Holland GN, Rao NA, Tabbara KF, Ohno S, et al. (2001) Revised diagnostic criteria for Vogt-Koyanagi-Harada disease: report of an international committee on nomenclature. American journal of ophthalmology 131: 647-652. (Pubitemid 32422124)
11. Davis J, Mittal K, Freidlin V, Mellow S, Optican D, et al. (1990) HLA associations and ancestry in Vogt-Koyanagi-Harada disease and sympathetic ophthalmia. Ophthalmology 97: 1137.
12. Zhao M, Jiang Y, Abrahams IW (1991) Association of HLA antigens with Vogt-Koyanagi-Harada syndrome in a Han Chinese population. Archives of ophthalmology 109: 368.
13. Jiang Z, Yang P, Hou S, Li F, Zhou H (2010) Polymorphisms of IL23R and Vogt-Koyanagi-Harada syndrome in a Chinese Han population. Human Immunology 71: 414-417.
14. Shu Q, Yang P, Hou S, Li F, Chen Y, et al. (2010) Interleukin-17 gene polymorphism is associated with Vogt-Koyanagi-Harada syndrome but not with Behçet's disease in a Chinese Han population. Human Immunology 71: 988-991.
15. Chu M, Yang P, Hu R, Hou S, Li F, et al. (2011) Elevated serum osteopontin levels and genetic polymorphisms of osteopontin are associated with Vogt-Koyanagi-Harada disease. Invest Ophthalmol Vis Sci 52: 7084-7089.
16. Au PY, Yeh WC (2007) Physiological roles and mechanisms of signaling by TRAF2 and TRAF5. Adv Exp Med Biol 597: 32-47.
17. Bulek K, Liu C, Swaidani S, Wang L, Page RC, et al. (2011) The inducible kinase IKKi is required for IL-17-dependent signaling associated with neutrophilia and pulmonary inflammation. Nat Immunol 12: 844-852.
18. Potter C, Eyre S, Cope A, Worthington J, Barton A (2007) Investigation of association between the TRAF family genes and RA susceptibility. Ann Rheum Dis 66: 1322-1326. (Pubitemid 47492475)
19. Ma AI (2012) The ubiquitous nature of IL-17. Nat Immunol 13: 1034-1035.
20. Doyle MS, Collins ES, Fitzgerald OM, Pennington SR (2012) New insight into the functions of the interleukin-17 receptor adaptor protein Act1 in psoriatic arthritis. Arthritis Res Ther 14: 226.
21. Sun D, Novotny M, Bulek K, Liu C, Li X, et al. (2011) Treatment with IL-17 prolongs the half-life of chemokine CXCL1 mRNA via the adaptor TRAF5 and the splicing-regulatory factor SF2 (ASF). Nature immunology 12: 853-860.
22. Rassi DM, Junta CM, Fachin AL, Sandrin-Garcia P, Mello S, et al. (2008) Gene expression profiles stratified according to type 1 diabetes mellitus susceptibility regions. Annals of the New York Academy of Sciences 1150: 282-289.
23. Ellinghaus E, Ellinghaus D, Stuart PE, Nair RP, Debrus S, et al. (2010) Genome-wide association study identifies a psoriasis susceptibility locus at TRAF3IP2. Nat Genet 42: 991-995.
24. Huffmeier U, Uebe S, Ekici AB, Bowes J, Giardina E, et al. (2010) Common variants at TRAF3IP2 are associated with susceptibility to psoriatic arthritis and psoriasis. Nat Genet 42: 996-999.
25. Ciccacci C, Biancone L, Di Fusco D, Ranieri M, Condino G, et al. (2012) TRAF3IP2 gene is associated with cutaneous extraintestinal manifestations in Inflammatory Bowel Disease. Journal of Crohn's and Colitis.
26. Bergholdt R, Brorsson C, Palleja A, Berchtold LA, Fløyel T, et al. (2012) Identification of novel type 1 diabetes candidate genes by integrating genome-wide association data, protein-protein interactions, and human pancreatic islet gene expression. Diabetes 61: 954-962.
27. O'Rielly DD, Rahman P (2011) Genetics of susceptibility and treatment response in psoriatic arthritis. Nat Rev Rheumatol 7: 718-732.
28. Chi W, Zhu X, Yang P, Liu X, Lin X, et al. (2008) Upregulated IL-23 and IL-17 in Behçet patients with active uveitis. Investigative ophthalmology & visual science 49: 3058-3064.
29. + T cells to produce IL-17 in Vogt-Koyanagi-Harada disease. Journal of allergy and clinical immunology 119: 1218-1224.
30. International Study Group for Behcet's Disease (1990) Criteria for diagnosis of Behcet's disease. Lancet 335: 1078-1080.
31. Kraus ZJ, Nakano H, Bishop GA (2009) TRAF5 is a critical mediator of in vitro signals and in vivo functions of LMP1, the viral oncogenic mimic of CD40. Proceedings of the National Academy of Sciences 106: 17140-17145.
32. Cerhan JR, Liu-Mares W, Fredericksen ZS, Novak AJ, Cunningham JM, et al. (2008) Genetic variation in tumor necrosis factor and the nuclear factor-kappaB canonical pathway and risk of non-Hodgkin's lymphoma. Cancer Epidemiol Biomarkers Prev 17: 3161-3169.
33. Snell LM, Lin GH, McPherson AJ, Moraes TJ, Watts TH (2011) T-cell intrinsic effects of GITR and 4-1BB during viral infection and cancer immunotherapy. Immunol Rev 244: 197-217.
34. Zhang D, Gu T, Forsberg E, Efendic S, Brismar K, et al. (2011) Genetic and functional effects of membrane metalloendopeptidase on diabetic nephropathy development. Am J Nephrol 34: 483-490.
35. Zirlik A, Bavendiek U, Libby P, MacFarlane L, Gerdes N, et al. (2007) TRAF-1, -2, -3, -5, and -6 are induced in atherosclerotic plaques and differentially mediate proinflammatory functions of CD40L in endothelial cells. Arterioscler Thromb Vasc Biol 27: 1101-1107. (Pubitemid 46641965)
36. Sugita S, Takase H, Taguchi C, Imai Y, Kamoi K, et al. (2006) Ocular infiltrating CD4+ T cells from patients with Vogt-Koyanagi-Harada disease recognize human melanocyte antigens. Invest Ophthalmol Vis Sci 47: 2547-2554. (Pubitemid 351639840)
37. Ohno S (1981) Immunological aspects of Behçet's and Vogt-Koyanagi-Harada's diseases. Trans Ophthalmol Soc UK 101: 335-341.
38. Fang W, Yang P (2008) Vogt-koyanagi-harada syndrome. Curr Eye Res 33: 517-523. (Pubitemid 351948483)
39. Yang P, Zhang Z, Zhou H, Li B, Huang X, et al. (2005) Clinical patterns and characteristics of uveitis in a tertiary center for uveitis in China. Curr Eye Res 30: 943-948. (Pubitemid 43154688)
40. Hu K, Yang P, Jiang Z, Hou S, Du L, et al. (2010) STAT4 polymorphism in a Chinese Han population with Vogt-Koyanagi-Harada syndrome and Behçet's disease. Human Immunology 71: 723-726.
41. Jørgensen TN, Giltiay NV, Johnson A, Li X (2009) The role of Act1 in the control of autoimmunity. The Epigenetics of Autoimmune Diseases: 55-74.
42. Dolcino M, Cozzani E, Riva S, Parodi A, Tinazzi E, et al. (2012) Gene expression profiling in dermatitis herpetiformis skin lesions. Clin Dev Immunol 2012: 198956.
43. Kitamei H, Iwabuchi K, Namba K, Yoshida K, Yanagawa Y, et al. (2006) Amelioration of experimental autoimmune uveoretinitis (EAU) with an inhibitor of nuclear factor-κB (NF-κB), pyrrolidine dithiocarbamate. Journal of leukocyte biology 79: 1193-1201. (Pubitemid 44835553)
44. Niccoli L, Nannini C, Benucci M, Chindamo D, Cassara E, et al. (2007) Long-term efficacy of infliximab in refractory posterior uveitis of Behcet's disease: a 24-month follow-up study. Rheumatology (Oxford) 46: 1161-1164. (Pubitemid 47050622)
45. Okada AA, Goto H, Ohno S, Mochizuki M (2012) Multicenter study of infliximab for refractory uveoretinitis in Behçet disease. Arch Ophthalmol 130: 592-598.
46. Qian Y, Liu C, Hartupee J, Altuntas CZ, Gulen MF, et al. (2007) The adaptor Act1 is required for interleukin 17-dependent signaling associated with autoimmune and inflammatory disease. Nature immunology 8: 247-256. (Pubitemid 46745374)
47. Hunter CA (2007) Act1-ivating IL-17 inflammation. Nat Immunol 8: 232-234.
48. Li H, Liu Q, Hou S, Du L, Zhou Q, et al. (2013) TNFAIP3 gene polymorphisms confer risk for Behcet's disease in a Chinese Han population. Hum Genet 132: 293-300.
49. Zhou Q, Hou S, Liang L, Li X, Tan X, et al. (2012) MicroRNA-146a and Ets-1 gene polymorphisms in ocular Behcet's disease and Vogt-Koyanagi-Harada syndrome. Ann Rheum Dis.
50. Jiang Z, Yang P, Hou S, Du L, Xie L, et al. (2010) IL-23R gene confers susceptibility to Behcet's disease in a Chinese Han population. Ann Rheum Dis 69: 1325-1328.
51. Nishimoto K, Kochi Y, Ikari K, Yamamoto K, Suzuki A, et al. (2010) Association study of TRAF1-C5 polymorphisms with susceptibility to rheumatoid arthritis and systemic lupus erythematosus in Japanese. Annals of the rheumatic diseases 69: 368-373.
52. Plenge RM, Seielstad M, Padyukov L, Lee AT, Remmers EF, et al. (2007) TRAF1-C5 as a risk locus for rheumatoid arthritis - a genomewide study. New England Journal of Medicine 357: 1199-1209. (Pubitemid 47443179)
53. Han TU, Bang SY, Kang C, Bae SC (2009) TRAF1 polymorphisms associated with rheumatoid arthritis susceptibility in Asians and in Caucasians. Arthritis & Rheumatism 60: 2577-2584.
54. Namjou B, Choi CB, Harley IT, Alarcón-Riquelme ME, Kelly JA, et al. (2012) Evaluation of TRAF6 in a large multiancestral lupus cohort. Arthritis & Rheumatism 64: 1960-1969.
55. Perricone C, Ciccacci C, Ceccarelli F, Di Fusco D, Spinelli FR, et al. (2013) TRAF3IP2 gene and systemic lupus erythematosus: association with disease susceptibility and pericarditis development. Immunogenetics 65: 703-709.
56. Ciccacci C, Biancone L, Di Fusco D, Ranieri M, Condino G, et al. (2013) TRAF3IP2 gene is associated with cutaneous extraintestinal manifestations in Inflammatory Bowel Disease. Journal of Crohn's and Colitis 7: 44-52.