Treatment with IL-17 prolongs the half-life of chemokine CXCL1 mRNA via the adaptor TRAF5 and the splicing-regulatory factor SF2 (ASF)

Nature Immunology

Volumn 12, Issue 9, 2011, Pages 853-860

  Sun, Dongxu ^a   Novotny, Michael ^a   Bulek, Katarzyna ^a   Liu, Caini ^a   Li, Xiaoxia ^a   Hamilton, Thomas ^a  

^a LERNER RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALTERNATIVE SPLICING FACTOR; CXCL1 CHEMOKINE; INTERLEUKIN 17; MESSENGER RNA; RNA BINDING PROTEIN; TUMOR NECROSIS FACTOR RECEPTOR ASSOCIATED FACTOR 2; TUMOR NECROSIS FACTOR RECEPTOR ASSOCIATED FACTOR 5; UNCLASSIFIED DRUG;

ALTERNATIVE RNA SPLICING; ARTICLE; GENE OVEREXPRESSION; HALF LIFE TIME; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN DEPLETION; SIGNAL TRANSDUCTION; STIMULATION;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ALTERNATIVE SPLICING; ANIMALS; CHEMOKINE CXCL1; FEMALE; HALF-LIFE; HELA CELLS; HUMANS; INFLAMMATION; INTERLEUKIN-17; MICE; MICE, KNOCKOUT; NUCLEAR PROTEINS; RNA PROCESSING, POST-TRANSCRIPTIONAL; RNA STABILITY; RNA, MESSENGER; RNA-BINDING PROTEINS; SIGNAL TRANSDUCTION; TH17 CELLS; TNF RECEPTOR-ASSOCIATED FACTOR 5; TRANSCRIPTION, GENETIC;

EID: 80052025535     PISSN: 15292908     EISSN: 15292916     Source Type: Journal    
DOI: 10.1038/ni.2081     Document Type: Article

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