Evaluation of TRAF6 in a large multiancestral lupus cohort

Arthritis and Rheumatism

Volumn 64, Issue 6, 2012, Pages 1960-1969

  Namjou, Bahram ^a   Choi, Chan Bum ^b   Harley, Isaac T W ^a   Alarcõn Riquelme, Marta E ^c,d,e   Kelly, Jennifer A ^d   Glenn, Stuart B ^d   Ojwang, Joshua O ^d   Adler, Adam ^d   Kim, Kwangwoo ^f   Gallant, Caroline J ^c   Boackle, Susan A ^h   Criswell, Lindsey A ⁱ   Kimberly, Robert P ^j   Brown, Elizabeth E ^j   Edberg, Jeffrey ^j   Alarcõn, Graciela S ^j   Stevens, Anne M ^k   Jacob, Chaim O ^l   Gilkeson, Gary S ^m   Kamen, Diane L ^m   Tsao, Betty P ⁿ   Anaya, Juan Manuel ^o   Kim, Eun Mi ^b   Park, So Yeon ^b   Sung, Yoon Kyoung ^b   Guthridge, Joel M ^d   Merrill, Joan T ^d   Petri, Michelle ^p   Ramsey Goldman, Rosalind ^q   Vilá, Luis M ^r   Niewold, Timothy B ^s   Martin, Javier ^t   Pons Estel, Bernardo A ^u   Vyse, Timothy J ^v   Freedman, Barry I ^w   Moser, Kathy L ^d   Gaffney, Patrick M ^d   Williams, Adrienne H ^w   Comeau, Mary E ^w   Reveille, John D ^x   Kang, Changwon ^f   James, Judith A ^y   Scofield, R Hal ^y   Langefeld, Carl D ^w   Kaufman, Kenneth M ^g   Harley, John B ^g   Bae, Sang Cheol ^b   more..

^a UNIVERSITY OF CINCINNATI COLLEGE OF MEDICINE   (United States)

^b Hanyang University Hospital for Rheumatic Diseases   (South Korea)

^c UPPSALA UNIVERSITY   (Sweden)

^d OKLAHOMA MEDICAL RESEARCH FOUNDATION   (United States)

^e UNIVERSITY OF GRANADA   (Spain)

^f Korea Advanced Institute of Science and Technology (KAIST)   (South Korea)

^g CINCINNATI CHILDREN'S HOSPITAL MEDICAL CENTER   (United States)

^h UNIVERSITY OF COLORADO   (United States)

ⁱ UNIVERSITY OF CALIFORNIA   (United States)

^j UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

^k UNIVERSITY OF WASHINGTON   (United States)

^l UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^m MEDICAL UNIVERSITY OF SOUTH CAROLINA   (United States)

ⁿ UNIVERSITY OF CALIFORNIA   (United States)

^o UNIVERSIDAD DEL ROSARIO   (Colombia)

^p JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^q NORTHWESTERN UNIVERSITY   (United States)

^r UNIVERSITY OF PUERTO RICO   (Puerto Rico)

^s UNIVERSITY OF CHICAGO   (United States)

^t INSTITUTO DE PARASITOLOGÍA Y BIOMEDICINA LÓPEZ NEYRA   (Spain)

^u Sanatorio Parque   (Argentina)

^v KING'S COLLEGE LONDON   (United Kingdom)

^w WAKE FOREST SCHOOL OF MEDICINE   (United States)

^x UNIVERSITY OF TEXAS   (United States)

^y UNIVERSITY OF OKLAHOMA HEALTH SCIENCES CENTER   (United States)

more..

Author keywords

[No Author keywords available]

Indexed keywords

TUMOR NECROSIS FACTOR RECEPTOR ASSOCIATED FACTOR 6;

AFRICAN AMERICAN; ARTICLE; CALCULATION; CONTROLLED STUDY; ETHNICITY; FEMALE; GENE LINKAGE DISEQUILIBRIUM; GENETIC ASSOCIATION; GENETIC HETEROGENEITY; GENOTYPE; HEREDITY; HUMAN; IMMUNITY; IMMUNOPATHOGENESIS; MAJOR CLINICAL STUDY; MALE; META ANALYSIS (TOPIC); ORGANOGENESIS; PEDIGREE ANALYSIS; POPULATION BASED CASE CONTROL STUDY; PRIORITY JOURNAL; RHEUMATOID ARTHRITIS; SIGNAL TRANSDUCTION; SINGLE NUCLEOTIDE POLYMORPHISM; SYSTEMIC LUPUS ERYTHEMATOSUS; THROMBOCYTOPENIA;

ALLELES; CASE-CONTROL STUDIES; COHORT STUDIES; FEMALE; GENE FREQUENCY; GENETIC ASSOCIATION STUDIES; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; HAPLOTYPES; HUMANS; LUPUS ERYTHEMATOSUS, SYSTEMIC; MALE; POLYMORPHISM, SINGLE NUCLEOTIDE; TNF RECEPTOR-ASSOCIATED FACTOR 6;

EID: 84861829947     PISSN: 00043591     EISSN: 15290131     Source Type: Journal    
DOI: 10.1002/art.34361     Document Type: Article

References (30)

1. Harley JB, Alarcon-Riquelme ME, Criswell LA, Jacob CO, Kimberly RP, Moser KL, et al. Genome-wide association scan in women with systemic lupus erythematosus identifies susceptibility variants in ITGAM, PXK, KIAA1542 and other loci. Nat Genet 2008; 40: 204-10.
2. Hom G, Graham RR, Modrek B, Taylor KE, Ortmann W, Garnier S, et al. Association of systemic lupus erythematosus with C8orf13-BLK and ITGAM-ITGAX. N Engl J Med 2008; 358: 900-9.
3. Graham RR, Cotsapas C, Davies L, Hackett R, Lessard CJ, Leon JM, et al. Genetic variants near TNFAIP3 on 6q23 are associated with systemic lupus erythematosus. Nat Genet 2008; 40: 1059-61.
4. Kozyrev SV, Abelson AK, Wojcik J, Zaghlool A, Linga Reddy MV, Sanchez E, et al. Functional variants in the B-cell gene BANK1 are associated with systemic lupus erythematosus. Nat Genet 2008; 40: 211-6.
5. Han JW, Zheng HF, Cui Y, Sun LD, Ye DQ, Hu Z, et al. Genome-wide association study in a Chinese Han population identifies nine new susceptibility loci for systemic lupus erythematosus. Nat Genet 2009; 41: 1234-7.
6. Inoue J, Ishida T, Tsukamoto N, Kobayashi N, Naito A, Azuma S, et al. Tumor necrosis factor receptor-associated factor (TRAF) family: adapter proteins that mediate cytokine signaling. Exp Cell Res 2000; 254: 14-24.
7. Kobayashi T, Walsh PT, Walsh MC, Speirs KM, Chiffoleau E, King CG, et al. TRAF6 is a critical factor for dendritic cell maturation and development. Immunity 2003; 19: 353-63.
8. Zapata JM, Krajewska M, Krajewski S, Kitada S, Welsh K, Monks A, et al. TNFR-associated factor family protein expression in normal tissues and lymphoid malignancies. J Immunol 2000; 165: 5084-96.
9. Amos CI, Chen WV, Lee A, Li W, Kern M, Lundsten R, et al. High-density SNP analysis of 642 Caucasian families with rheumatoid arthritis identifies two new linkage regions on 11p12 and 2q33. Genes Immun 2006; 7: 277-86.
10. Raychaudhuri S, Thomson BP, Remmers EF, Eyre S, Hinks A, Guiducci C, et al. Genetic variants at CD28, PRDM1 and CD2/CD58 are associated with rheumatoid arthritis risk. Nat Genet 2009; 41: 1313-8.
11. Sandling JK, Garnier S, Sigurdsson S, Wang C, Nordmark G, Gunnarsson I, et al. A candidate gene study of the type I interferon pathway implicates IKBKE and IL8 as risk loci for SLE. Eur J Hum Genet 2011; 19: 479-84.
12. Scofield RH, Bruner GR, Kelly JA, Kilpatrick J, Bacino D, Nath SK, et al. Thrombocytopenia identifies a severe familial phenotype of systemic lupus erythematosus and reveals genetic linkages at 1q22 and 11p13. Blood 2003; 101: 992-7.
13. Kaufman KM, Rankin J, Harley IT, Kelly JA, Harley JB, Scofield RH,. A genetic marker within the CD44 gene confirms linkage at 11p13 in African-American families with lupus stratified by thrombocytopenia, but genetic association with CD44 is not present. Genes Immun 2002; 3 Suppl 1: S86-8.
14. Nath SK, Namjou B, Kilpatrick J, Garriott CP, Bruner GR, Scofield RH, et al. A candidate region on 11p13 for systemic lupus erythematosus: a linkage identified in African-American families. J Investig Dermatol Symp Proc 2004; 9: 64-7.
15. Kaufman KM, Kelly JA, Herring BJ, Adler AJ, Glenn SB, Namjou B, et al. Evaluation of the genetic association of the PTPN22 R620W polymorphism in familial and sporadic systemic lupus erythematosus. Arthritis Rheum 2006; 54: 2533-40.
16. Jacob CO, Reiff A, Armstrong DL, Myones BL, Silverman E, Klein-Gitelman M, et al. Identification of novel susceptibility genes in childhood-onset systemic lupus erythematosus using a uniquely designed candidate gene pathway platform. Arthritis Rheum 2007; 56: 4164-73.
17. Cooper GS, Parks CG, Treadwell EL, St Clair EW, Gilkeson GS, Cohen PL, et al. Differences by race, sex and age in the clinical and immunologic features of recently diagnosed systemic lupus erythematosus patients in the southeastern United States. Lupus 2002; 11: 161-7.
18. Alarcon GS, McGwin G Jr, Petri M, Ramsey-Goldman R, Fessler BJ, Vila LM, et al. Time to renal disease and end-stage renal disease in PROFILE: a multiethnic lupus cohort. PLoS Med 2006; 3: e396.
19. Hochberg MC, for the Diagnostic and Therapeutic Criteria Committee of the American College of Rheumatology. Updating the American College of Rheumatology revised criteria for the classification of systemic lupus erythematosus [letter]. Arthritis Rheum 1997; 40: 1725.
20. Purcell S, Neale B, Todd-Brown K, Thomas L, Ferreira MA, Bender D, et al. PLINK: a tool set for whole-genome association and population-based linkage analyses. Am J Hum Genet 2007; 81: 559-75.
21. Barrett JC, Fry B, Maller J, Daly MJ,. Haploview: analysis and visualization of LD and haplotype maps. Bioinformatics 2005; 21: 263-5.
22. Horvath S, Xu X, Laird NM,. The family based association test method: strategies for studying general genotype-phenotype associations. Eur J Hum Genet 2001; 9: 301-6.
23. Purcell S, Daly MJ, Sham PC,. WHAP: haplotype-based association analysis. Bioinformatics 2007; 23: 255-6.
24. Price AL, Patterson NJ, Plenge RM, Weinblatt ME, Shadick NA, Reich D,. Principal components analysis corrects for stratification in genome-wide association studies. Nat Genet 2006; 38: 904-9.
25. Harley IT, Kaufman KM, Langefeld CD, Harley JB, Kelly JA,. Genetic susceptibility to SLE: new insights from fine mapping and genome-wide association studies. Nat Rev Genet 2009; 10: 285-90.
26. Starczynowski DT, Kuchenbauer F, Argiropoulos B, Sung S, Morin R, Muranyi A, et al. Identification of miR-145 and miR-146a as mediators of the 5q- syndrome phenotype. Nat Med 2010; 16: 49-58.
27. Chiffoleau E, Kobayashi T, Walsh MC, King CG, Walsh PT, Hancock WW, et al. TNF receptor-associated factor 6 deficiency during hemopoiesis induces Th2-polarized inflammatory disease. J Immunol 2003; 171: 5751-9.
28. Yang XR, Pfeiffer RM, Wheeler W, Yeager M, Chanock S, Tucker MA, et al. Identification of modifier genes for cutaneous malignant melanoma in melanoma-prone families with and without CDKN2A mutations. Int J Cancer 2009; 125: 2912-7.
29. Schultheiss U, Puschner S, Kremmer E, Mak TW, Engelmann H, Hammerschmidt W, et al. TRAF6 is a critical mediator of signal transduction by the viral oncogene latent membrane protein 1. EMBO J 2001; 20: 5678-91.
30. Ning S, Campos AD, Darnay BG, Bentz GL, Pagano JS,. TRAF6 and the three C-terminal lysine sites on IRF7 are required for its ubiquitination-mediated activation by the tumor necrosis factor receptor family member latent membrane protein 1. Mol Cell Biol 2008; 28: 6536-46.