Salvianolic acid B promotes osteogenesis of human mesenchymal stem cells through activating ERK signaling pathway

International Journal of Biochemistry and Cell Biology

Volumn 51, Issue 1, 2014, Pages 1-9

  Xu, Daohua ^a,b   Xu, Liangliang ^b,d   Zhou, Chenhui ^a   Lee, Wayne Y W ^b,c,d   Wu, Tie ^a   Cui, Liao ^a   Li, Gang ^b,c,d  

^a GUANGDONG MEDICAL UNIVERSITY   (China)

^b CHINESE UNIVERSITY OF HONG KONG   (Hong Kong)

^c CHINESE UNIVERSITY OF HONG KONG   (Hong Kong)

^d Prince of Wales Hospital   (Hong Kong)

Author keywords

Mesenchymal stem cell; Osteogenesis; Osteoporosis; Salvianolic acid B

Indexed keywords

ALKALINE PHOSPHATASE; MITOGEN ACTIVATED PROTEIN KINASE; OSTEOPONTIN; SALVIANOLIC ACID B; BENZOFURAN DERIVATIVE; HERBACEOUS AGENT;

ARTICLE; BONE DEVELOPMENT; CELL DIFFERENTIATION; CYTOTOXICITY; HUMAN; HUMAN CELL; MESENCHYMAL STEM CELL; MINERALIZATION; NONHUMAN; OSTEOPOROSIS; SALVIA MILTIORRHIZA; CELL SURVIVAL; CYTOLOGY; DRUG EFFECTS; ENZYMOLOGY; GENETIC TRANSFECTION; MESENCHYMAL STROMA CELL; METABOLISM; SIGNAL TRANSDUCTION;

BENZOFURANS; CELL DIFFERENTIATION; CELL SURVIVAL; DRUGS, CHINESE HERBAL; HUMANS; MAP KINASE SIGNALING SYSTEM; MESENCHYMAL STROMAL CELLS; OSTEOGENESIS; OSTEOPOROSIS; TRANSFECTION;

EID: 84897391234     PISSN: 13572725     EISSN: 18785875     Source Type: Journal    
DOI: 10.1016/j.biocel.2014.03.005     Document Type: Article

References (44)

1. P. Benisch, T. Schilling, L. Klein-Hitpass, S.P. Frey, L. Seefried, and N. Raaijmakers et al. The transcriptional profile of mesenchymal stem cell populations in primary osteoporosis is distinct and shows overexpression of osteogenic inhibitors PLoS ONE 7 2012 e45142
2. T.H. Chen, W.M. Chen, K.H. Hsu, C.D. Kuo, and S.C. Hung Sodium butyrate activates ERK to regulate differentiation of mesenchymal stem cells Biochem Biophys Res Commun 355 2007 913 918
3. L. Cui, T. Li, Y.Y. Liu, L. Zhou, P.H. Li, and B.L. Xu et al. Salvianolic acid B prevents bone loss in prednisone-treated rats through stimulation of osteogenesis and bone marrow angiogenesis PLoS ONE 2012 7
4. L. Dalle Carbonare, M.T. Valenti, M. Zanatta, L. Donatelli, and V. Lo Cascio Circulating mesenchymal stem cells with abnormal osteogenic differentiation in patients with osteoporosis Arthritis Rheum 60 2009 3356 3365
5. R.J. Deans, and A.B. Moseley Mesenchymal stem cells: biology and potential clinical uses Exp Hematol 28 2000 875 884
6. P. Ducy, R. Zhang, V. Geoffroy, A.L. Ridall, and G. Karsenty Osf2/Cbfa1: a transcriptional activator of osteoblast differentiation Cell 89 1997 747 754 (Pubitemid 27516177)
7. C. Ge, G. Xiao, D. Jiang, and R.T. Franceschi Critical role of the extracellular signal-regulated kinase-MAPK pathway in osteoblast differentiation and skeletal development J Cell Biol 176 2007 709 718 (Pubitemid 46333984)
8. J.A. Gordon, C.E. Tye, A.V. Sampaio, T.M. Underhill, G.K. Hunter, and H.A. Goldberg Bone sialoprotein expression enhances osteoblast differentiation and matrix mineralization in vitro Bone 41 2007 462 473 (Pubitemid 47199144)
9. M. Guan, W. Yao, R. Liu, K.S. Lam, J. Nolta, and J. Jia et al. Directing mesenchymal stem cells to bone to augment bone formation and increase bone mass Nat Med 18 2012 456 462
10. G. Harrison, I.M. Shapiro, and E.E. Golub The phosphatidylinositol- glycolipid anchor on alkaline phosphatase facilitates mineralization initiation in vitro J Bone Miner Res 10 1995 568 573
11. H. He, M. Shi, X. Zeng, J. Yang, Y. Li, and L. Wu et al. Cardioprotective effect of salvianolic acid B on large myocardial infarction mediated by reversing upregulation of leptin, endothelin pathways, and abnormal expression of SERCA2a, phospholamban in rats J Ethnopharmacol 118 2008 35 45
12. S.K. Hong, S. Yoon, C. Moelling, D. Arthan, and J.I. Park Noncatalytic function of ERK1/2 can promote Raf/MEK/ERK-mediated growth arrest signaling J Biol Chem 284 2009 33006 33018
13. R.K. Jaiswal, N. Jaiswal, S.P. Bruder, G. Mbalaviele, D.R. Marshak, and M.F. Pittenger Adult human mesenchymal stem cell differentiation to the osteogenic or adipogenic lineage is regulated by mitogen-activated protein kinase J Biol Chem 275 2000 9645 9652 (Pubitemid 30185197)
14. Y.H. Jiang, B.N. Jahagirdar, R.L. Reinhardt, R.E. Schwartz, C.D. Keene, and X.R. Ortiz-Gonzalez et al. Pluripotency of mesenchymal stem cells derived from adult marrow Nature 418 2002 41 49 (Pubitemid 34742565)
15. Y. Joe, M. Zheng, H.J. Kim, S. Kim, M.J. Uddin, and C. Park et al. Salvianolic acid B exerts vasoprotective effects through the modulation of heme oxygenase-1 and arginase activities J Pharmacol Exp Ther 341 2012 850 858
16. J.A. Kanis, E.V. McCloskey, H. Johansson, and A. Oden Approaches to the targeting of treatment for osteoporosis Nat Rev Rheumatol 5 2009 425 431
17. D.H. Kim, S.J. Park, J.M. Kim, S.J. Jeon, Y.W. Cho, and K.H. Son et al. Cognitive dysfunctions induced by a cholinergic blockade and Abeta 25-35 peptide are attenuated by salvianolic acid B Neuropharmacology 61 2011 1432 1440
18. Y.J. Kim, H.N. Kim, E.K. Park, B.H. Lee, H.M. Ryoo, and S.Y. Kim et al. The bone-related Zn finger transcription factor Osterix promotes proliferation of mesenchymal cells Gene 366 2006 145 151
19. T. Komori, H. Yagi, S. Nomura, A. Yamaguchi, K. Sasaki, and K. Deguchi et al. Targeted disruption of Cbfa1 results in a complete lack of bone formation owing to maturational arrest of osteoblasts Cell 89 1997 755 764 (Pubitemid 27516178)
20. S. Kumar, C. Wan, G. Ramaswamy, T.L. Clemens, and S. Ponnazhagan Mesenchymal stem cells expressing osteogenic and angiogenic factors synergistically enhance bone formation in a mouse model of segmental bone defect Mol Ther 18 2010 1026 1034
21. C.F. Lai, L. Chaudhary, A. Fausto, L.R. Halstead, D.S. Ory, and L.V. Avioli et al. Erk is essential for growth, differentiation, integrin expression, and cell function in human osteoblastic cells J Biol Chem 276 2001 14443 14450
22. C.H. Lee, Y.L. Huang, J.F. Liao, and W.F. Chiou Ugonin K promotes osteoblastic differentiation and mineralization by activation of p38 MAPK- and ERK-mediated expression of Runx2 and osterix Eur J Pharmacol 668 2011 383 389
23. Y.W. Lee, D.H. Kim, S.J. Jeon, S.J. Park, J.M. Kim, and J.M. Jung et al. Neuroprotective effects of salvianolic acid B on an Abeta(2)(5)(-)(3)(5) peptide-induced mouse model of Alzheimer's disease Eur J Pharmacol 704 2013 70 77
24. B.Y. Lu, Z.Z. Ye, Y.B. Deng, H.F. Wu, and J.Q. Feng MEK/ERK pathway mediates cytoprotection of salvianolic acid B against oxidative stress-induced apoptosis in rat bone marrow stem cells Cell Biol Int 34 2010 1063 1068
25. P.J. Marie, and M. Kassem Osteoblasts in osteoporosis: past, emerging, and future anabolic targets Eur J Endocrinol 165 2011 1 10
26. H. Miraoui, K. Oudina, H. Petite, Y. Tanimoto, K. Moriyama, and P.J. Marie Fibroblast growth factor receptor 2 promotes osteogenic differentiation in mesenchymal cells via ERK1/2 and protein kinase C signaling J Biol Chem 284 2009 4897 4904
27. K. Nakashima, X. Zhou, G. Kunkel, Z.P. Zhang, J.M. Deng, and R.R. Behringer et al. The novel zinc finger-containing transcription factor Osterix is required for osteoblast differentiation and bone formation Cell 108 2002 17 29 (Pubitemid 34137009)
28. H. Orimo The mechanism of mineralization and the role of alkaline phosphatase in health and disease J Nippon Med Sch 77 2010 4 12
29. H. Orimo, and T. Shimada The role of tissue-nonspecific alkaline phosphatase in the phosphate-induced activation of alkaline phosphatase and mineralization in SaOS-2 human osteoblast-like cells Mol Cell Biochem 315 2008 51 60
30. D. Park, A.P. Xiang, F.F. Mao, L. Zhang, C.G. Di, and X.M. Liu et al. Nestin is required for the proper self-renewal of neural stem cells Stem Cells 28 2010 2162 2171
31. A.M. Pino, C.J. Rosen, and J.P. Rodriguez In osteoporosis, differentiation of mesenchymal stem cells (MSCs) improves bone marrow adipogenesis Biol Res 45 2012 279 287
32. M.F. Pittenger, A.M. Mackay, S.C. Beck, R.K. Jaiswal, R. Douglas, and J.D. Mosca et al. Multilineage potential of adult human mesenchymal stem cells Science 284 1999 143 147 (Pubitemid 29282067)
33. L.G. Raisz Pathogenesis of osteoporosis: concepts, conflicts, and prospects J Clin Invest 115 2005 3318 3325 (Pubitemid 43121814)
34. J.P. Rodriguez, L. Montecinos, S. Rios, P. Reyes, and J. Martinez Mesenchymal stem cells from osteoporotic patients produce a type I collagen-deficient extracellular matrix favoring adipogenic differentiation J Cell Biochem 79 2000 557 565
35. S.K. Sandhu, and G. Hampson The pathogenesis, diagnosis, investigation and management of osteoporosis J Clin Pathol 64 2011 1042 1050
36. A.S. Shekkeris, P.K. Jaiswal, and W.S. Khan Clinical applications of mesenchymal stem cells in the treatment of fracture non-union and bone defects Curr Stem Cell Res Ther 7 2012 127 133
37. W.T. Tse, W. Beyer, J.D. Pendleton, A. D'Andrea, and E.C. Guinan Bone marrow-derived mesenchymal stem cells suppress T cell activation without inducing allogeneic anergy Blood 96 2000 241a 250a
38. Q. Tu, P. Valverde, and J. Chen Osterix enhances proliferation and osteogenic potential of bone marrow stromal cells Biochem Biophys Res Commun 341 2006 1257 1265 (Pubitemid 43221800)
39. A. Undale, D. Fraser, T. Hefferan, R.A. Kopher, J. Herrick, and G.L. Evans et al. Induction of fracture repair by mesenchymal cells derived from human embryonic stem cells or bone marrow J Orthop Res 29 2011 1804 1811
40. R. Wang, X.Y. Yu, Z.Y. Guo, Y.J. Wang, Y. Wu, and Y.F. Yuan Inhibitory effects of salvianolic acid B on CCl(4)-induced hepatic fibrosis through regulating NF-kappaB/IkappaBalpha signaling J Ethnopharmacol 144 2012 592 598
41. G. Xiao, D. Jiang, P. Thomas, M.D. Benson, K. Guan, and G. Karsenty et al. MAPK pathways activate and phosphorylate the osteoblast-specific transcription factor, Cbfa1 J Biol Chem 275 2000 4453 4459 (Pubitemid 30094689)
42. L. Xu, C. Song, M. Ni, F. Meng, H. Xie, and G. Li Cellular retinol-binding protein 1 (CRBP-1) regulates osteogenenesis and adipogenesis of mesenchymal stem cells through inhibiting RXRalpha-induced beta-catenin degradation Int J Biochem Cell Biol 44 2012 612 619
43. K.L. Yao, R. Todescan Jr., and J. Sodek Temporal changes in matrix protein synthesis and mRNA expression during mineralized tissue formation by adult rat bone marrow cells in culture J Bone Miner Res 9 1994 231 240 (Pubitemid 24041568)
44. Z. Zhao, M. Zhao, G. Xiao, and R.T. Franceschi Gene transfer of the Runx2 transcription factor enhances osteogenic activity of bone marrow stromal cells in vitro and in vivo Mol Ther 12 2005 247 253 (Pubitemid 41025094)