Osterix enhances proliferation and osteogenic potential of bone marrow stromal cells

Biochemical and Biophysical Research Communications

Volumn 341, Issue 4, 2006, Pages 1257-1265

  Tu, Qisheng ^a   Valverde, Paloma ^a   Chen, Jake ^a  

^a TUFTS UNIVERSITY SCHOOL OF DENTAL MEDICINE   (United States)

Author keywords

BMSC; Cbfa1 Runx2; Differentiation; Osterix; Proliferation; RCAS TVA

Indexed keywords

ALKALINE PHOSPHATASE; BIOLOGICAL MARKER; LIPOPROTEIN LIPASE; OSTEOCALCIN; OSTEOPONTIN; PROCOLLAGEN; RETROVIRUS VECTOR; SIALOPROTEIN; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR RUNX2; TRASCRIPTION FACTOR OSTERIX; UNCLASSIFIED DRUG;

ADIPOGENESIS; ANIMAL CELL; ANIMAL CELL CULTURE; ARTICLE; BONE DEVELOPMENT; BONE MARROW CELL; BONE MARROW STROMAL CELL; BONE MINERALIZATION; CELL DIFFERENTIATION; CELL LINEAGE; CELL PROLIFERATION; CHONDROGENESIS; CONTROLLED STUDY; ENZYME ACTIVITY; GENE OVEREXPRESSION; GENETIC TRANSDUCTION; IN VITRO STUDY; MOUSE; NONHUMAN; OSTEOBLAST; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN INDUCTION;

ALKALINE PHOSPHATASE; ANIMALS; BONE MARROW CELLS; CELL DIFFERENTIATION; CELL PROLIFERATION; CORE BINDING FACTOR ALPHA 1 SUBUNIT; MICE; OSTEOGENESIS; STROMAL CELLS; TRANSCRIPTION FACTORS; TRANSDUCTION, GENETIC;

ANIMALIA; MURINAE;

EID: 32344432473     PISSN: 0006291X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbrc.2006.01.092     Document Type: Article

References (29)

1. H. Petite, V. Viateau, W. Bensaid, A. Meunier, C. de Pollak, M. Bourguignon, K. Oudina, L. Sedel, and G. Gillemin Tissue-engineered bone regeneration Nat. Biotechnol. 18 2000 959 963
2. B.C. Heng, T. Cao, L.W. Stanton, P. Robson, and B.R. Olsen Strategies for directing the differentiation of stem cells into the osteogenic lineage in vitro J. Bone Miner. Res. 19 2004 1379 1394
3. D.W. Hutmacher, and A.J. Garcia Scaffold-based bone engineering by using genetically modified cells Gene 347 2005 1 10
4. P. Bianco, M. Riminucci, S. Gronthos, and P.G. Robey Bone marrow stromal stem cells: nature, biology and potential applications Stem Cells 19 2001 180 192
5. A. Banfi, G. Bianchi, R. Notaro, L. Luzzatto, R. Cancedda, and R. Quarto Replicative aging and gene expression in long-term cultures of human bone marrow stromal cells Tissue Eng. 8 2002 901 910
6. A.R. Derubeis, and R. Cancedda Bone marrow stromal cells (BMSCs) in bone engineering: limitations and recent advances Ann. Biomed. Eng. 32 2004 160 165
7. P. Ducy, R. Zhang, V. Geoffroy, A.L. Ridall, and G. Karsenty Osf2/Cbfa1: a transcriptional activator of osteoblast differentiation Cell 89 1997 677 680
8. T. Komori, H. Yagi, S. Nomura, A. Yamaguchi, K. Sasaki, K. Deguchi, Y. Shimizu, R.T. Bronson, Y.H. Gao, M. Inada, M. Sato, R. Okamoto, Y. Kitamura, S. Yoshiki, and T. Kishimoto Targeted disruption of Cbfa1 results in a complete lack of bone formation owing to maturational arrest of osteoblasts Cell 89 1997 755 764
9. F. Otto, A.P. Thornell, T. Cromptom, A. Denzel, K.C. Gilmour, I.R. Rosewell, G.W. Stamp, R.S. Beddington, S. Mundlos, B.R. Olsen, P.B. Selby, and M.J. Owen Cbfa1, a candidate gene for cleidocranial dysplasia syndrome, is essential for osteoblastic differentiation and bone development Cell 89 1997 765 771
10. A.L. Bronckers, K. Sasaguri, A.C. Cavender, R.N. D'Souza, and M.A. Engelse Expression of Runx2/Cbfa1/Pebp2alphaA during angiogenesis in postnatal rodent and fetal human orofacial tissues J. Bone Miner. Res. 10 2005 428 437
11. W. Liu, S. Toyosawa, T. Furuichi, N. Kanatani, C. Yoshida, Y. Liu, M. Himeno, S. Narai, A. Yamaguchi, and T. Komori Overexpression of Cbfa1 in osteoblasts inhibits osteoblast maturation and causes osteopenia with multiple fractures J. Cell Biol. 155 2001 157 166
12. H. Zheng, Z. Guo, Q. Ma, H. Jia, and G. Dang Cbfa1/osf2 transduced bone marrow stromal cells facilitate bone formation in vitro and in vivo Calcif. Tissue Int. 74 2004 194 203
13. B.A. Byers, and A.J. Garcia Exogenous Runx2 expression enhances in vitro osteoblastic differentiation and mineralization in primary bone marrow stromal cells Tissue Eng. 10 2004 1623 1632
14. K. Nakashima, X. Zhou, G. Kunkel, Z. Zhang, J.M. Deng, R.R. Behringer, and B. de Crombrugghe The novel zinc finger-containing transcription factor osterix is required for osteoblast differentiation and bone formation Cell 108 2002 17 29
15. G. Tai, J.M. Polak, A.E. Bishop, I. Christodoulou, and L.D.K. Buttery Differentiation of osteoblasts from murine embryonic stem cells by overexpression of the transcription factor osterix Tissue Eng. 10 2004 1456 1466
16. M.J. Federspiel, and S.H. Hughes Retroviral gene delivery Methods Cell Biol. 52 1997 179 214
17. E.C. Holland, and H.E. Varmus Basic fibroblast growth factor induces cell migration and proliferation after glia-specific gene transfer in mice Proc. Natl. Acad. Sci. USA 95 1998 1218 1223
18. L. Li, J. Zhu, Q. Tu, M. Yamauchi, J. Sodek, G. Karsenty, J. Tang, and J. Chen An in vivo model to study osteogenic gene regulation: targeting an avian retroviral receptor (TVA) to bone with the bone sialoprotein (BSP) promoter J. Bone Miner. Res. 20 2005 1403 1413
19. K. Satomura, P. Krebsbach, P. Bianco, and P.G. Robey Osteogenic imprinting upstream of marrow stromal cell differentiation J. Cell Biochem. 78 2000 391 403
20. Q. Tu, M. Yamauchi, S.C. Pageau, and J.J. Chen Autoregulation of bone sialoprotein gene in pre-osteoblastic and non-osteoblastic cells Biochem. Biophys. Res. Commun. 316 2004 461 467
21. P. Valverde, M.S. Obin, and A. Taylor Role of Gas6/Axl signaling in lens epithelial cell proliferation and survival Exp. Eye Res. 78 2004 27 37
22. P. Valverde, Q. Tu, and J. Chen BSP and RANKL induce osteoclastogenesis and bone resorption synergistically J. Bone Miner. Res. 20 2005 1669 1679
23. A. Banfi, A. Muraglia, B. Dozin, M. Mastrogiacomo, R. Cancedda, and R. Quarto Proliferation, kinetics and differentiation potential of ex vivo expanded human bone marrow stromal cells: Implications for their use in cell therapy Exp. Hematol. 28 2000 707 715
24. P. Bosch, S.L. Pratt, and S.L. Stice Isolation, characterization, gene modification, and nuclear reprogramming of porcine mesenchymal stem cells Biol. Reprod. 74 2006 46 57
25. G. Tai, I. Christodoulou, A.E. Bishop, and J.M. Polak Use of green fluorescent fusion protein to track activation of transcription of the transcription factor osterix during early osteoblast differentiation Biochem. Biophys. Res. Commun. 333 2005 1116 1122
26. L.D. Buttery, S. Bourne, J.D. Xynos, H. Wood, F.J. Hughes, S.P. Hughes, V. Episkopou, and J.M. Polak Differentiation of osteoblasts and in vitro bone formation from murine embryonic stem cells Tissue Eng. 7 2001 89 99
27. J.N. Beresford, C.J. Joyner, C. Devlin, and J.T. Triffitt The effects of dexamethasone and 1,25-dihydroxyvitamin D3 on osteogenic differentiation of human marrow stromal cells in vitro Arch. Oral Biol. 39 1994 941 947
28. M. Igarashi, N. Kamiya, M. Hasegawa, T. Kasuya, T. Takahashi, and M. Takagi Inductive effects of dexamethasone on the gene expression of Cbfa1, Osterix and bone matrix proteins during differentiation of cultured primary rat osteoblasts J. Mol. Histol. 35 2004 3 10
29. Y.J. Kim, H.N. Kim, E.K. Park, B.H. Lee, H.M. Ryoo, S.Y. Kim, I.S. Kim, J.L. Stein, J.B. Lian, G.S. Stein, A.J. van Wijnen, and J.Y. Choi The bone-related Zn finger transcription factor Osterix promotes proliferation of mesenchymal cells Gene 25 2005 [Epub ahead of print]