Deregulation of subcellular biometal homeostasis through loss of the metal transporter, Zip7, in a childhood neurodegenerative disorder

Acta Neuropathologica Communications

Volumn 2, Issue 1, 2014, Pages

  Grubman, Alexandra ^a   Lidgerwood, Grace E ^a   Duncan, Clare ^a   Bica, Laura ^a   Tan, Jiang Li ^a   Parker, Sarah J ^a,b   Caragounis, Aphrodite ^a   Meyerowitz, Jodi ^a   Volitakis, Irene ^a   Moujalled, Diane ^a   Liddell, Jeffrey R ^a   Hickey, James L ^c   Horne, Malcolm ^a   Longmuir, Shoshanah ^a   Koistinaho, Jari ^b   Donnelly, Paul S ^c   Crouch, Peter J ^a   Tammen, Imke ^d   White, Anthony R ^a   Kanninen, Katja M ^a,b  

^a UNIVERSITY OF MELBOURNE   (Australia)

^b UNIVERSITY OF EASTERN FINLAND   (Finland)

^c UNIVERSITY OF MELBOURNE   (Australia)

^d UNIVERSITY OF SYDNEY   (Australia)

Author keywords

Biometal homeostasis; CLN6; Neurodegeneration; Neuronal ceroid lipofuscinoses; Zip7

Indexed keywords

ALANINE-SERINE-TROPOMYOSIN; ALKALINE PHOSPHATASE; CATION TRANSPORT PROTEIN; CLN6 PROTEIN, HUMAN; DIPEPTIDE; MEMBRANE PROTEIN; METAL; SLC39A7 PROTEIN, HUMAN; TROPOMYOSIN; ZINC;

AGE; ANIMAL; ANIMAL EMBRYO; ASTROCYTE; CELL CULTURE; DEFICIENCY; DEGENERATIVE DISEASE; DISEASE MODEL; DRUG EFFECTS; ENZYMOLOGY; GENETICS; HOMEOSTASIS; HUMAN; METABOLISM; MOUSE; MUTATION; PATHOLOGY; SHEEP; TRANSGENIC MOUSE; TRANSPORT AT THE CELLULAR LEVEL; UPREGULATION;

AGE FACTORS; ALKALINE PHOSPHATASE; ANIMALS; ASTROCYTES; BIOLOGICAL TRANSPORT; CATION TRANSPORT PROTEINS; CELLS, CULTURED; DIPEPTIDES; DISEASE MODELS, ANIMAL; EMBRYO, MAMMALIAN; HOMEOSTASIS; HUMANS; MEMBRANE PROTEINS; METALS; MICE; MICE, TRANSGENIC; MUTATION; NEURODEGENERATIVE DISEASES; SHEEP; TROPOMYOSIN; UP-REGULATION; ZINC;

EID: 84897389235     PISSN: None     EISSN: 20515960     Source Type: Journal    
DOI: 10.1186/2051-5960-2-25     Document Type: Article

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