Altered functional connectivity of the marginal division in Alzheimer's disease

Current Alzheimer Research

Volumn 11, Issue 2, 2014, Pages 145-155

  Zhang, Zengqiang ^a,c   Liu, Yong ^b   Zhou, Bo ^a   Zheng, Jinlong ^d   Yao, Hongxiang ^a   An, Ningyu ^a   Wang, Pan ^a   Guo, Yan'e ^a   Dai, Haitao ^c   Wang, Luning ^a   Shu, Siyun ^e   Zhang, Xi ^a   Jiang, Tianzi ^b,f  

^a CHINESE PLA GENERAL HOSPITAL   (China)

^b INSTITUTE OF AUTOMATION   (China)

^c Hainan Branch of Chinese PLA General Hospital   (China)

^d XUZHOU MEDICAL UNIVERSITY   (China)

^e SOUTHERN MEDICAL UNIVERSITY   (China)

^f UNIVERSITY OF ELECTRONIC SCIENCE AND TECHNOLOGY OF CHINA   (China)

Author keywords

Alzheimer's disease; Functional connectivity; Marginal division; Mild cognitive impairment; Resting state fMRI

Indexed keywords

AGED; ALZHEIMER DISEASE; AMYGDALOID NUCLEUS; ARTICLE; BRAIN FUNCTION; BRAIN REGION; CEREBELLUM; CLINICAL ARTICLE; CONTROLLED STUDY; DISEASE SEVERITY; FEMALE; FOLLOW UP; FUNCTIONAL MAGNETIC RESONANCE IMAGING; HUMAN; INFERIOR FRONTAL GYRUS; MALE; MARGINAL DIVISION; MILD COGNITIVE IMPAIRMENT; NEUROPSYCHOLOGICAL TEST; NEUROPSYCHOLOGY; PARAHIPPOCAMPAL GYRUS; PRIORITY JOURNAL; SUPERIOR TEMPORAL GYRUS; BRAIN; BRAIN MAPPING; METABOLISM; MIDDLE AGED; NERVE CELL NETWORK; NUCLEAR MAGNETIC RESONANCE IMAGING; PATHOLOGY; PHYSIOLOGY; PROCEDURES; PSYCHOLOGY; VERY ELDERLY;

AGED; AGED, 80 AND OVER; ALZHEIMER DISEASE; BRAIN; BRAIN MAPPING; FEMALE; HUMANS; MAGNETIC RESONANCE IMAGING; MALE; MIDDLE AGED; MILD COGNITIVE IMPAIRMENT; NERVE NET;

EID: 84897380779     PISSN: 15672050     EISSN: 18755828     Source Type: Journal    
DOI: 10.2174/1567205011666140110112608     Document Type: Article

References (91)

1. Petersen RC. Early diagnosis of Alzheimer's disease: is MCI too late? Curr Alzheimer Res 6(4): 324-30 (2009).
2. Petersen RC. Mild cognitive impairment: current research and clinical implications. Semin Neurol 27(1): 22-31 (2007).
3. Farias ST, Mungas D, Reed BR, Harvey D, DeCarli C. Progression of mild cognitive impairment to dementia in clinic-vs communitybased cohorts. Arch Neurol 66(9): 1151-7 (2009).
4. Gauthier S, Reisberg B, Zaudig M, Petersen RC, Ritchie K, Broich K, et al. Mild cognitive impairment. Lancet 367(9518): 1262-70 (2006).
5. Sperling RA, Aisen PS, Beckett LA, Bennett DA, Craft S, Fagan AM, et al. Toward defining the preclinical stages of Alzheimer's disease: recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease. Alzheimers Dement 7(3): 280-92 (2011).
6. Jack CR, Jr., Knopman DS, Jagust WJ, Shaw LM, Aisen PS, Weiner MW, et al. Hypothetical model of dynamic biomarkers of the Alzheimer's pathological cascade. Lancet Neurol 9(1): 119-28 (2010).
7. Wang L, Zang Y, He Y, Liang M, Zhang X, Tian L, et al. Changes in hippocampal connectivity in the early stages of Alzheimer's disease: evidence from resting state fMRI. Neuroimage 31(2): 496-504 (2006).
8. Wang K, Liang M, Wang L, Tian L, Zhang X, Li K, et al. Altered functional connectivity in early Alzheimer's disease: a resting-state fMRI study. Human brain mapping 28(10): 967-78 (2007).
9. Bai F, Watson DR, Yu H, Shi Y, Yuan Y, Zhang Z. Abnormal resting-state functional connectivity of posterior cingulate cortex in amnestic type mild cognitive impairment. Brain Res 1302: 167-74 (2009).
10. Bai F, Zhang Z, Watson DR, Yu H, Shi Y, Yuan Y, et al. Abnormal functional connectivity of hippocampus during episodic memory retrieval processing network in amnestic mild cognitive impairment. Biol Psychiatry 65(11): 951-8 (2009).
11. Liu Y, Wang K, Yu C, He Y, Zhou Y, Liang M, et al. Regional homogeneity, functional connectivity and imaging markers of Alzheimer's disease: a review of resting-state fMRI studies. Neuropsychologia 46(6): 1648-56 (2008).
12. Wang Z, Jia X, Liang P, Qi Z, Yang Y, Zhou W, et al. Changes in thalamus connectivity in mild cognitive impairment: evidence from resting state fMRI. Eur J Radiol 81(2): 277-85 (2012).
13. Xie C, Bai F, Yu H, Shi Y, Yuan Y, Chen G, et al. Abnormal insula functional network is associated with episodic memory decline in amnestic mild cognitive impairment. Neuroimage 63(1): 320-7 (2012).
14. Liu Y, Yu C, Zhang X, Liu J, Duan Y, Alexander-Bloch AF, et al. Impaired Long Distance Functional Connectivity and Weighted Network Architecture in Alzheimer's Disease. Cereb Cortex (2013).
15. Zhao X, Liu Y, Wang X, Liu B, Xi Q, Guo Q, et al. Disrupted small-world brain networks in moderate Alzheimer's disease: a resting-state FMRI study. PloS one 7(3): e33540 (2012).
16. Wang Z, Liang P, Jia X, Jin G, Song H, Han Y, et al. The baseline and longitudinal changes of PCC connectivity in mild cognitive impairment: a combined structure and resting-state fMRI study. PloS one 7(5): e36838 (2012).
17. Shu SY, Penny GR, Peterson GM. The 'marginal division': a new subdivision in the neostriatum of the rat. J Chem Neuroanat 1(3): 147-63 (1988).
18. Shu SY, Bao XM, Peterson GM. Ultrastructure of the marginal division in the rat striatum. Chin Med J (Engl) 105(2): 102-9 (1992).
19. Shu SY, Bao XM, Zhang C, Li SX, Chan WY, Yew D. A new subdivision, marginal division, in the neostriatum of the monkey brain. Neurochem Res 25(2): 231-7 (2000).
20. Shu SY, Wu YM, Bao XM, Wen ZB, Huang FH, Li SX, et al. A new area in the human brain associated with learning and memory: immunohistochemical and functional MRI analysis. Mol Psychiatry 7(9): 1018-22 (2002).
21. Ning Q, Shu SY, Bao XM. Functional connection between the marginal division and hippocampus in rats. Di Yi Jun Yi Da Xue Xue Bao 22(8): 684-6 (2002).
22. Li YY, Shu SY, Bao XM, Wu WL. The connection among the marginal division of striatum, amygdaliod nucleus and bed nucleus of the stria terminalis in the rat brain as revealed by immunohistochemistry. Chinese J Neuroanat 16(3): 265-68 (2000).
23. Shu SY. Marginal division of the neostriatum: a subcortical memory center. J Biomed Sci 10(1): 14-29 (2003).
24. Shu SY, Wu YM, Bao XM, Leonard B. Interactions among memory-related centers in the brain. J Neurosci Res 71(5): 609-16 (2003).
25. Shu SY, Bao X, Li S, Niu D, Xu Z, Li Y. A new subdivision of mammalian neostriatum with functional implications to learning and memory. J Neurosci Res 58(2): 242-53 (1999).
26. Shu SY, Bao XM, Wu YM, Wang J, Leonard B. Hippocampal long-term potentiation attenuated by lesions in the marginal division of neostriatum. Neurochem Res 28(5): 743-7 (2003).
27. Liu XM, Shu SY, Zeng CC, Cai YF, Zhang KH, Wang CX, et al. The role of substance P in the marginal division of the neostriatum in learning and memory is mediated through the neurokinin 1 receptor in rats. Neurochem Res 36(10): 1896-902 (2011).
28. Wang C, Shu SY, Guo Z, Cai YF, Bao X, Zeng C, et al. Immunohistochemical localization of mu opioid receptor in the marginal division with comparison to patches in the neostriatum of the rat brain. J Biomed Sci 18: 34 (2011).
29. Shu SY, Song C, Wu Y, Mo L, Guo Z, Liu SH, et al. Learning and memory deficits caused by a lesion in the medial area of the left putamen in the human brain. CNS Spectr 14(9): 473-6 (2009).
30. Hopper MW, Vogel FS. The limbic system in Alzheimer's disease. A neuropathologic investigation. Am J Pathol 85(1): 1-20 (1976).
31. Ball MJ. "Limbic predilection in Alzheimer dementia: is reactivated herpesvirus involved?". Can J Neurol Sci 9(3): 303-6 (1982).
32. Callen DJ, Black SE, Gao F, Caldwell CB, Szalai JP. Beyond the hippocampus: MRI volumetry confirms widespread limbic atrophy in AD. Neurology 57(9): 1669-74 (2001).
33. Choo IH, Lee DY, Oh JS, Lee JS, Lee DS, Song IC, et al. Posterior cingulate cortex atrophy and regional cingulum disruption in mild cognitive impairment and Alzheimer's disease. Neurobiol Aging 31(5): 772-9 (2010).
34. Blesa R, Mohr E, Miletich RS, Chase TN. Limbic system dysfunction in Alzheimer's disease. J Neurol Neurosurg Psychiatry 59(4): 450-1 (1995).
35. Nestor PJ, Fryer TD, Smielewski P, Hodges JR. Limbic hypometabolism in Alzheimer's disease and mild cognitive impairment. Ann Neurol 54(3): 343-51(2003).
36. Callen DJ, Black SE, Caldwell CB, Grady CL. The influence of sex on limbic volume and perfusion in AD. Neurobiol Aging 25(6): 761-70 (2004).
37. Hirao K, Ohnishi T, Matsuda H, Nemoto K, Hirata Y, Yamashita F, et al. Functional interactions between entorhinal cortex and posterior cingulate cortex at the very early stage of Alzheimer's disease using brain perfusion single-photon emission computed tomography. Nucl Med Commun 27(2): 151-6 (2006).
38. Bozoki AC, Korolev IO, Davis NC, Hoisington LA, Berger KL. Disruption of limbic white matter pathways in mild cognitive impairment and Alzheimer's disease: a DTI/FDG-PET study. Human brain mapping 33(8): 1792-802 (2012).
39. Delbeuck X, Collette F, Van der Linden M. Is Alzheimer's disease a disconnection syndrome? Evidence from a crossmodal audiovisual illusory experiment. Neuropsychologia 45(14): 3315-23 (2007).
40. Delbeuck X, Van der Linden M, Collette F. Alzheimer's disease as a disconnection syndrome? Neuropsychology review 13(2): 79-92 (2003).
41. Zhang Z, Liu Y, Jiang T, Zhou B, An N, Dai H, et al. Altered spontaneous activity in Alzheimer's disease and mild cognitive impairment revealed by Regional Homogeneity. Neuroimage 59(2): 1429-40 (2012).
42. Yao H, Liu Y, Zhou B, Zhang Z, An N, Wang P, et al. Decreased functional connectivity of the amygdala in Alzheimer's disease revealed by resting-state fMRI. Euro J Radiol 82(9): 1531-38 (2013).
43. Zhou B, Liu Y, Zhang Z, An N, Yao H, Wang P, et al. Impaired functional connectivity of the thalamus in alzheimer' s disease and mild cognitive impairment: a resting-state FMRI study. Curr Alzheimer Res 10(7): 754-66 (2013).
44. Power JD, Barnes KA, Snyder AZ, Schlaggar BL, Petersen SE. Spurious but systematic correlations in functional connectivity MRI networks arise from subject motion. Neuroimage 59(3): 2142-54 (2012).
45. Satterthwaite TD, Wolf DH, Loughead J, Ruparel K, Elliott MA, Hakonarson H, et al. Impact of in-scanner head motion on multiple measures of functional connectivity: relevance for studies of neurodevelopment in youth. Neuroimage 60(1): 623-32 (2012).
46. Van Dijk KR, Sabuncu MR, Buckner RL. The influence of head motion on intrinsic functional connectivity MRI. Neuroimage 59(1): 431-8 (2012).
47. Yan CG, Cheung B, Kelly C, Colcombe S, Craddock RC, Di Martino A, et al. A comprehensive assessment of regional variation in the impact of head micromovements on functional connectomics. Neuroimage 76: 183-201 (2013).
48. Shu SY, Bao XM, Ning Q, Wu YM, Wang J, Leonard BE. New component of the limbic system: Marginal division of the neostriatum that links the limbic system to the basal nucleus of Meynert. J Neurosci Res 71(5): 751-7 (2003).
49. Dice L. Measures of the amount of ecologic association between species. Ecology 26(3): 297-302 (1945).
50. Seger CA, Cincotta CM. The roles of the caudate nucleus in human classification learning. J Neurosci 25(11): 2941-51 (2005).
51. Monchi O, Petrides M, Strafella AP, Worsley KJ, Doyon J. Functional role of the basal ganglia in the planning and execution of actions. Ann Neurol 59(2): 257-64 (2006).
52. Wolf DS, Gearing M, Snowdon DA, Mori H, Markesbery WR, Mirra SS. Progression of regional neuropathology in Alzheimer disease and normal elderly: findings from the Nun study. Alzheimer disease and associated disorders 13(4): 226-31 (1999).
53. Almeida OP, Burton EJ, McKeith I, Gholkar A, Burn D, O'Brien JT. MRI study of caudate nucleus volume in Parkinson's disease with and without dementia with Lewy bodies and Alzheimer's disease. Dement Geriatr Cogn Disord 16(2): 57-63 (2003).
54. Madsen SK, Ho AJ, Hua X, Saharan PS, Toga AW, Jack CR, Jr., et al. 3D maps localize caudate nucleus atrophy in 400 Alzheimer's disease, mild cognitive impairment, and healthy elderly subjects. Neurobiol Aging 31(8): 1312-25 (2010).
55. Agosta F, Rocca MA, Pagani E, Absinta M, Magnani G, Marcone A, et al. Sensorimotor network rewiring in mild cognitive impairment and Alzheimer's disease. Human brain mapping 31(4): 515-25 (2010).
56. Ries ML, McLaren DG, Bendlin BB, Guofanxu, Rowley HA, Birn R, et al. Medial prefrontal functional connectivity--relation to memory self-appraisal accuracy in older adults with and without memory disorders. Neuropsychologia 50(5): 603-11(2012).
57. Han SD, Arfanakis K, Fleischman DA, Leurgans SE, Tuminello ER, Edmonds EC, et al. Functional connectivity variations in mild cognitive impairment: associations with cognitive function. J Intern Neuropsychol Soc: JINS 18(1): 39-48.(2012).
58. Morris JS, Ohman A, Dolan RJ. Conscious and unconscious emotional learning in the human amygdala. Nature 393(6684): 467-70 (1998).
59. Pessoa L, McKenna M, Gutierrez E, Ungerleider LG. Neural processing of emotional faces requires attention. Proc Natl Acad Sci USA 99(17): 11458-63 (2002).
60. Vuilleumier P, Armony JL, Clarke K, Husain M, Driver J, Dolan RJ. Neural response to emotional faces with and without awareness: event-related fMRI in a parietal patient with visual extinction and spatial neglect. Neuropsychologia 40(12): 2156-66 (2002).
61. Whalen PJ, Rauch SL, Etcoff NL, McInerney SC, Lee MB, Jenike MA. Masked presentations of emotional facial expressions modulate amygdala activity without explicit knowledge. J Neurosci 18(1): 411-8 (1998).
62. Phelps EA. Emotion and cognition: insights from studies of the human amygdala. Annual review of psychology 57: 27-53 (2006).
63. Schaefer A, Gray JR. A role for the human amygdala in higher cognition. Rev Neurosci 18(5): 355-63 (2007).
64. Pessoa L. Emotion and cognition and the amygdala: from "what is it?" to "what's to be done?". Neuropsychologia 48(12): 3416-29 (2010).
65. Sabatinelli D, Bradley MM, Fitzsimmons JR, Lang PJ. Parallel amygdala and inferotemporal activation reflect emotional intensity and fear relevance. Neuroimage 24(4): 1265-70 (2005).
66. Mackiewicz KL, Sarinopoulos I, Cleven KL, Nitschke JB. The effect of anticipation and the specificity of sex differences for amygdala and hippocampus function in emotional memory. Proc Natl Acad Sci USA 103(38): 14200-5 (2006).
67. Nitschke JB, Sarinopoulos I, Mackiewicz KL, Schaefer HS, Davidson RJ. Functional neuroanatomy of aversion and its anticipation. Neuroimage 29(1): 106-16 (2006).
68. Phelps EA. Human emotion and memory: interactions of the amygdala and hippocampal complex. Curr Opin Neurobiol 14(2): 198-202 (2004).
69. Kim JJ, Lee HJ, Han JS, Packard MG. Amygdala is critical for stress-induced modulation of hippocampal long-term potentiation and learning. J Neurosci 21(14): 5222-8 (2001).
70. Korz V, Frey JU. Bidirectional modulation of hippocampal longterm potentiation under stress and no-stress conditions in basolateral amygdala-lesioned and intact rats. J Neurosci 25(32): 7393-400 (2005).
71. Kile SJ, Ellis WG, Olichney JM, Farias S, DeCarli C. Alzheimer abnormalities of the amygdala with Kluver-Bucy syndrome symp toms: an amygdaloid variant of Alzheimer disease. Arch Neurol 66(1): 125-9 (2009).
72. Frisoni GB, Lorenzi M, Caroli A, Kemppainen N, Nagren K, Rinne JO. In vivo mapping of amyloid toxicity in Alzheimer disease. Neurology 72(17): 1504-11(2009).
73. Basso M, Yang J, Warren L, MacAvoy MG, Varma P, Bronen RA, et al. Volumetry of amygdala and hippocampus and memory performance in Alzheimer's disease. Psychiatry Res 146(3): 251-61 (2006).
74. Horinek D, Petrovicky P, Hort J, Krasensky J, Brabec J, Bojar M, et al. Amygdalar volume and psychiatric symptoms in Alzheimer's disease: an MRI analysis. Acta neurologica Scandinavica 113(1): 40-5 (2006).
75. Horinek D, Varjassyova A, Hort J. Magnetic resonance analysis of amygdalar volume in Alzheimer's disease. Curr Opin Psychiat 20(3): 273-7 (2007).
76. Poulin SP, Dautoff R, Morris JC, Barrett LF, Dickerson BC, Alzheimer's Disease Neuroimaging I. Amygdala atrophy is prominent in early Alzheimer's disease and relates to symptom severity. Psychiatry Res 194(1): 7-13(2011).
77. den Heijer T, Geerlings MI, Hoebeek FE, Hofman A, Koudstaal PJ, Breteler MM. Use of hippocampal and amygdalar volumes on magnetic resonance imaging to predict dementia in cognitively intact elderly people. Arch Gen Psychiatry 63(1): 57-62 (2006).
78. Wright CI, Dickerson BC, Feczko E, Negeira A, Williams D. A functional magnetic resonance imaging study of amygdala responses to human faces in aging and mild Alzheimer's disease. Biol Psychiatry 62(12): 1388-95 (2007).
79. Grady CL, Furey ML, Pietrini P, Horwitz B, Rapoport SI. Altered brain functional connectivity and impaired short-term memory in Alzheimer's disease. Brain 124(Pt 4): 739-56 (2001).
80. Stoodley CJ, Schmahmann JD. Functional topography in the human cerebellum: a meta-analysis of neuroimaging studies. Neuroimage 44(2): 489-501 (2009).
81. Timmann D, Daum I. Cerebellar contributions to cognitive functions: a progress report after two decades of research. Cerebellum 6(3): 159-62 (2007).
82. Guillozet AL, Weintraub S, Mash DC, Mesulam MM. Neurofibrillary tangles, amyloid, and memory in aging and mild cognitive impairment. Arch Neurol 60(5): 729-36 (2003).
83. Tiraboschi P, Hansen LA, Thal LJ, Corey-Bloom J. The importance of neuritic plaques and tangles to the development and evolution of AD. Neurology 62(11): 1984-9.(2004).
84. Kovacevic S, Rafii MS, Brewer JB. High-throughput, fully automated volumetry for prediction of MMSE and CDR decline in mild cognitive impairment. Alzheimer disease and associated disorders 23(2): 139-45 (2009).
85. Bottino CM, Castro CC, Gomes RL, Buchpiguel CA, Marchetti RL, Neto MR. Volumetric MRI measurements can differentiate Alzheimer's disease, mild cognitive impairment, and normal aging. Int Psychogeriatr 14(1): 59-72 (2002).
86. Luckhaus C, Flub MO, Wittsack HJ, Grass-Kapanke B, Janner M, Khalili-Amiri R, et al. Detection of changed regional cerebral blood flow in mild cognitive impairment and early Alzheimer's dementia by perfusion-weighted magnetic resonance imaging. Neuroimage 40(2): 495-503 (2008).
87. Roh JH, Qiu A, Seo SW, Soon HW, Kim JH, Kim GH, et al. Volume reduction in subcortical regions according to severity of Alzheimer's disease. J Neurol 258(6): 1013-20 (2011).
88. Koivunen J, Karrasch M, Scheinin NM, Aalto S, Vahlberg T, Nagren K, et al. Cognitive decline and amyloid accumulation in patients with mild cognitive impairment. Dement Geriatr Cogn Disord 34(1): 31-7 (2012).
89. Amieva H, Le Goff M, Millet X, Orgogozo JM, Peres K, Barberger-Gateau P, et al. Prodromal Alzheimer's disease: successive emergence of the clinical symptoms. Ann Neurol 64(5): 492-8 (2008).
90. Baldwin S, Farias ST. Neuropsychological assessment in the diagnosis of Alzheimer's disease. Current protocols in neuroscience / editorial board, Jacqueline N Crawley [et al.] Chapter 10: Unit10 3.(2009).
91. He Y, Wang L, Zang Y, Tian L, Zhang X, Li K, et al. Regional coherence changes in the early stages of Alzheimer's disease: a combined structural and resting-state functional MRI study. Neuroimage 35(2): 488-500 (2007).