The influence of sex on limbic volume and perfusion in AD

Neurobiology of Aging

Volumn 25, Issue 6, 2004, Pages 761-770

  Callen, David J A ^a,b   Black, Sandra E ^a,b   Caldwell, Curtis B ^a   Grady, Cheryl L ^c,d  

^a SUNNYBROOK RESEARCH INSTITUTE   (Canada)

^b UNIVERSITY OF TORONTO   (Canada)

^c ROTMAN RESEARCH INSTITUTE   (Canada)

^d UNIVERSITY OF TORONTO   (Canada)

Author keywords

Alzheimer's disease; Coregistration; Limbic system; MRI; Sex differences; SPECT

Indexed keywords

ADULT; AGED; ALZHEIMER DISEASE; ANTHROPOMETRY; ARTICLE; ATROPHY; BRAIN PERFUSION; BRAIN REGION; BRAIN SIZE; CINGULATE GYRUS; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; HUMAN; HYPOTHALAMUS; LIMBIC CORTEX; LIMBIC SYSTEM; MALE; MAMMILLARY BODY; NEUROIMAGING; NUCLEAR MAGNETIC RESONANCE IMAGING; ORBITAL CORTEX; PERFUSION; PRIORITY JOURNAL; SEX DIFFERENCE; SINGLE PHOTON EMISSION COMPUTER TOMOGRAPHY; THALAMUS ANTERIOR NUCLEUS;

AGED; ALZHEIMER DISEASE; CASE-CONTROL STUDIES; FEMALE; HUMANS; LIMBIC SYSTEM; MAGNETIC RESONANCE IMAGING; MALE; PERFUSION; SEX CHARACTERISTICS; TECHNETIUM TC 99M EXAMETAZIME; TOMOGRAPHY, EMISSION-COMPUTED, SINGLE-PHOTON;

EID: 2542580858     PISSN: 01974580     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neurobiolaging.2003.08.011     Document Type: Article

References (54)

1. American Psychiatric Association. Diagnostic and statistical manual of mental disorders, 3rd ed. Washington, DC: American Psychiatric Association; 1987.
2. Azcoitia I., Sierra A., Veiga S., Honda S., Harada N.L.M. Brain aromatase is neuroprotective. J. Neurobiol. 47(4):2001;318-329
3. Bierer L.M., Hof P.R., Purohit D.P., Carlin L., Schmeidler J., Davis K.L., et al. Neocortical neurofibrillary tangles correlate with dementia severity in Alzheimer's disease. Arch. Neurol. 52(1):1995;81-88
4. Braak H., Braak E. Neuropathological stageing of Alzheimer-related changes. Acta Neuropathol. 82:1991;239-259
5. Braak H., Braak E., Bohl J. Staging of Alzheimer-related cortical destruction. Eur. Neurol. 33:1993;403-408
6. Brun A., Gustafson L. Distribution of cerebral degeneration in Alzheimer's disease. A clinico-pathological study. Arch. Psychiat. Nervenkr. 223:1976;15-33
7. Callen D.J., Black S.E., Gao F., Caldwell C.B., Szalai J.P. Beyond the hippocampus: MRI volumetry confirms widespread limbic atrophy in AD. Neurology. 57(9):2001;1669-1674
8. Callen D.J.A., Black S.E., Caldwell C. Limbic system perfusion in Alzheimer's disease measured by MRI-coregistered HMPAO SPET. Eur. J. Nucl. Med. 29(7):2002;899-906
9. Chang L.-T. A method for attenuation correction on radionuclide computed tomography. IEEE Trans. Nucl. Sci. 25:1978;638-643
10. Chung S.K., Pfaff D.W., Cohen R.S. Estrogen-induced alterations in synaptic morphology in the midbrain central gray. Exp. Brain Res. 69(3):1988;522-530
11. Coffey C.E., Wilkinson W.E., Parashos I.A., Soady S.A., Sullivan R.J., Patterson L.J., et al. Quantitative cerebral anatomy of the aging human brain: a cross-sectional study using magnetic resonance imaging. Neurology. 42(3 Pt 1):1992;527-536
12. Cohen J. Statistical power analysis for the behavioral sciences, 2nd ed. Hillsdale, NJ: Lawrence Erlbaum Associates; 1988. p. 273-406.
13. de Courten-Myers G.M. The human cerebral cortex: gender differences in structure and function. J. Neuropathol. Exp. Neurol. 58(3):1999;217-226
14. Duff S.J., Hampson E. A beneficial effect of estrogen on working memory in postmenopausal women taking hormone replacement therapy. Horm. Behav. 38(4):2000;262-276
15. Fernandez-Guasti A., Kruijver F.P., Fodor M., Swaab D.F. Sex differences in the distribution of androgen receptors in the human hypothalamus. J. Comp. Neurol. 425(3):2000;422-435
16. Flores C., Salmaso N., Cain S., Rodaros D., Stewart J. Ovariectomy of adult rats leads to increased expression of astrocytic basic fibroblast growth factor in the ventral tegmental area and in dopaminergic projection regions of the entorhinal and prefrontal cortex. J. Neurosci. 19(19):1999;8665-8673
17. Golomb J., de Leon M.J., Kluger A., George A.E., Tarshish C., Ferris S.H. Hippocampal atrophy in normal aging. An association with recent memory impairment. Arch. Neurol. 50(9):1993;967-973
18. Goudsmit E., Hofman M.A., Fliers E., Swaab D.F. The supraoptic and paraventricular nuclei of the human hypothalamus in relation to sex, age and Alzheimer's disease. Neurobiol. Aging. 11(5):1990;529-536
19. Gur R.C., Mozley P.D., Resnick S.M., Gottlieb G.L., Kohn M., Zimmerman R., et al. Gender differences in age effect on brain atrophy measured by magnetic resonance imaging. Proc. Natl. Acad. Sci. U.S.A. 88(7):1991;2845-2849
20. Gur R.C., Turetsky B.I., Matsui M., Yan M., Bilker W., Hughett P., et al. Sex differences in brain gray and white matter in healthy young adults: correlations with cognitive performance. J. Neurosci. 19(10):1999;4065-4072
21. Hammond J., Le Q., Goodyer C., Gelfand M., Trifiro M., LeBlanc A. Testosterone-mediated neuroprotection through the androgen receptor in human primary neurons. J. Neurochem. 77(5):2001;1319-1326
22. Hebert L.E., Scherr P.A., McCann J.J., Beckett L.A., Evans D.A. Is the risk of developing Alzheimer's disease greater for women than for men? Am. J. Epidemiol. 153(2):2001;132-136
23. Jorm A.F., Korten A.E., Henderson A.S. The prevalence of dementia: a quantitative integration of the literature. Acta Psychiatr. Scand. 76:1987;465-479
24. Juni JE, Waxman AD, Devous Sr MD, Tikofsky RS, Ichise M, Van Heertum R, et al. Society of nuclear medicine procedure guideline for brain perfusion single photon emission computed tomography (SPECT) using Tc-99m radiopharmaceuticals 2.0. In: Society of nuclear medicine procedure guidelines manual 2001-2002. New York: Society of Nuclear Medicine; 2001. p. 105-10.
25. Juottonen K., Laakso M.P., Insausti R., Lehtovirta M., Pitkanen A., Partanen K., et al. Volumes of the entorhinal and perirhinal cortices in Alzheimer's disease. Neurobiol. Aging. 19(1):1998;15-22
26. Kidron D., Black S.E., Stanchev P., Buck B., Szalai J.P., Parker J., et al. Quantitative MR volumetry in Alzheimer's disease. Topographic markers and the effects of sex and education. Neurology. 49(6):1997;1504-1512
27. Kushwaha R.S., Foster D.M., Barrett P.H., Carey K.D., Bernard M.G. Metabolic regulation of plasma apolipoprotein E by estrogen and progesterone in the baboon (Papio sp.). Metabolism. 40(1):1991;93-100
28. Lobaugh N.J., Caldwell C.B., Black S.E., Leibovitch F.S., Swartz R.H. Three brain SPECT region-of-interest templates in elderly people: normative values, hemispheric asymmetries, and a comparison of single- and multihead cameras. J. Nucl. Med. 41(1):2000;45-56
29. Lopez L., Brana M., Burgos P., Arias J.L. Structural dimorphism in the mammillary bodies of the rat. Neurosci. Lett. 176(2):1994;197-200
30. McKhann G., Drachman D., Folstein M., Katzman R., Price D., Stadlan E.M. Clinical diagnosis of Alzheimer's disease: report of the NINCDS-ADRDA Work Group under the auspices of Department of Health and Human Services Task Force on Alzheimer's disease. Neurology. 34:1984;939-944
31. Murphy D.G., DeCarli C., McIntosh A.R., Daly E., Mentis M.J., Pietrini P., et al. Sex differences in human brain morphometry and metabolism: an in vivo quantitative magnetic resonance imaging and positron emission tomography study on the effect of aging. Arch. Gen. Psychiatry. 53(7):1996;585-594
32. Nagy Z., Hindley N.J., Braak H., Braak E., Yilmazer-Hanke D.M., Schultz C., et al. The progression of Alzheimer's disease from limbic regions to the neocortex: clinical, radiological and pathological relationships. Dement. Geriatr. Cogn. Disord. 10(2):1999;115-120
33. Paredes R.G., Baum M.J. Role of the medial preoptic area/anterior hypothalamus in the control of masculine sexual behavior. Annu. Rev. Sex Res. 8:1997;68-101
34. Paus T., Otaky N., Caramanos Z., MacDonald D., Zijdenbos A., D'Avirro D., et al. In vivo morphometry of the intrasulcal gray matter in the human cingulate, paracingulate, and superior-rostral sulci: hemispheric asymmetries, gender differences and probability maps. J. Comp. Neurol. 376(4):1996;664-673
35. Paus T., Tomaiuolo F., Otaky N., MacDonald D., Petrides M., Atlas J., et al. Human cingulate and paracingulate sulci: pattern, variability, asymmetry, and probabilistic map. Cereb. Cortex. 6(2):1996;207-214
36. Polo-Kantola P., Portin R., Polo O., Helenius H., Irjala K., Erkkola R. The effect of short-term estrogen replacement therapy on cognition: a randomized, double-blind, cross-over trial in postmenopausal women. Obstet. Gynecol. 91(3):1998;459-466
37. Rabinowicz T., Dean D.E., Petetot J.M., de Courten-Myers G.M. Gender differences in the human cerebral cortex: more neurons in males; more processes in females. J. Child Neurol. 14(2):1999;98-107
38. Rapp S.R., Espeland M.A., Shumaker S.A., Henderson V.W., Brunner R.L., Manson J.E., et al. Effect of estrogen plus progestin on global cognitive function in postmenopausal women. The women's health initiative memory study: a randomized controlled trial. JAMA. 289(20):2003;2663-2672
39. Raz N., Gunning-Dixon F.M., Head D., Dupuis J.H., Acker J.D. Neuroanatomical correlates of cognitive aging: evidence from structural magnetic resonance imaging. Neuropsychology. 12(1):1998;95-114
40. Salat D.H., Stangl P.A., Kaye J.A., Janowsky J.S. Sex differences in prefrontal volume with aging and Alzheimer's disease. Neurobiol. Aging. 20(6):1999;591-596
41. Schultz C., Braak H., Braak E. A sex difference in neurodegeneration of the human hypothalamus. Neurosci. Lett. 212(2):1996;103-106
42. Schultz C., Ghebremedhin E., Braak E., Braak H. Sex-dependent cytoskeletal changes of the human hypothalamus develop independently of Alzheimer's disease. Exp. Neurol. 160(1):1999;186-193
43. Sherwin B.B. Estrogen and cognitive functioning in women. Endocr. Rev. 24(2):2003;133-151
44. Shughrue P.J., Merchenthaler I. Estrogen is more than just a "sex hormone": novel sites for estrogen action in the hippocampus and cerebral cortex. Front Neuroendocrinol. 21(1):2000;95-101
45. Sowell E.R., Trauner D.A., Gamst A., Jernigan T.L. Development of cortical and subcortical brain structures in childhood and adolescence: a structural MRI study. Dev. Med. Child Neurol. 44(1):2002;4-16
46. Stern Y., Gurland B., Tatemichi T.K., Tang M.X., Wilder D., Mayeux R. Influence of education and occupation on the incidence of Alzheimer's disease. JAMA. 271(13):1994;1004-1010
47. Stone D.J., Rozovsky I., Morgan T.E., Anderson C.P., Finch C.E. Increased synaptic sprouting in response to estrogen via an apolipoprotein E-dependent mechanism: implications for Alzheimer's disease. J. Neurosci. 18(9):1998;3180-3185
48. Swaab D.F., Fliers E. A sexually dimorphic nucleus in the human brain. Science. 228(4703):1985;1112-1115
49. Talairach J, Tournoux P. Co-planar stereotaxic atlas of the human brain. New York: Georg Thieme; 1988.
50. Tierney M.C., Fisher R.H., Lewis A.J., Zorzitto M.L., Snow W.G., Reid D.W., et al. The NINCDS-ADRDA Work Group criteria for the clinical diagnosis of probable Alzheimer's disease: a clinicopathologic study of 57 cases. Neurology. 38(3):1988;359-364
51. 99mTc -ECD brain perfusion SPET: variability, asymmetry and effects of age and gender in healthy adults Eur. J. Nucl. Med. 28(7):2001;873-887
52. Wespes E., Schulman C.C. Male andropause: myth, reality, and treatment. Int. J. Impot. Res. 14(Suppl. 1):2002;S93-S98
53. Witelson S.F., Glezer I.I., Kigar D.L. Women have greater density of neurons in posterior temporal cortex. J. Neurosci. 15(5 Pt 1):1995;3418-3428
54. Woods R.P., Mazziotta J.C., Cherry S.R. MRI-PET registration with automated algorithm. J. Comput. Assist. Tomogr. 17(4):1993;536-546