The volatile anesthetic isoflurane differentially suppresses the induction of erythropoietin synthesis elicited by acute anemia and systemic hypoxemia in mice in an hypoxia-inducible factor-2-dependent manner

European Journal of Pharmacology

Volumn 732, Issue 1, 2014, Pages 43-49

  Kai, Shinichi ^a   Tanaka, Tomoharu ^a   Matsuyama, Tomonori ^a   Suzuki, Kengo ^a   Hirota, Kiichi ^a,b  

^a KYOTO UNIVERSITY HOSPITAL   (Japan)

^b KANSAI MEDICAL UNIVERSITY   (Japan)

Author keywords

Anemia; Anesthetic; Erythropoietin; Hypoxia; Hypoxia inducible factor; Isoflurane

Indexed keywords

BASIC HELIX LOOP HELIX TRANSCRIPTION FACTOR; ENDOTHELIAL PAS DOMAIN-CONTAINING PROTEIN 1; ERYTHROPOIETIN; INHALATION ANESTHETIC AGENT; ISOFLURANE;

ANEMIA; ANIMAL; ANOXIA; ANTAGONISTS AND INHIBITORS; BIOSYNTHESIS; BRAIN LEVEL; C57BL MOUSE; DRUG EFFECTS; HEMODYNAMICS; KIDNEY; MALE; METABOLISM; MOUSE; PHYSIOLOGY;

ANEMIA; ANESTHETICS, INHALATION; ANIMALS; ANOXIA; BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTORS; BRAIN CHEMISTRY; ERYTHROPOIETIN; HEMODYNAMICS; ISOFLURANE; KIDNEY; MALE; MICE; MICE, INBRED C57BL;

EID: 84897361584     PISSN: 00142999     EISSN: 18790712     Source Type: Journal    
DOI: 10.1016/j.ejphar.2014.03.020     Document Type: Article

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