Brain adenosine signaling in psychological trauma and comorbid depression

Neurobiology of Post-Traumatic Stress Disorder

Volumn , Issue , 2011, Pages 229-257

  Minor, Thomas R ^a   Plumb, Traci N ^a   Schell, Christopher J ^a   Pham, Anh K ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

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EID: 84897165377     PISSN: None     EISSN: None     Source Type: Book    
DOI: None     Document Type: Chapter

References (168)

1. Hoge CW, Terhakopian A, Castro CA, Messer SC, Engel CC: Association of posttraumatic stress disorder with somatic symptoms, health care visits, and absenteeism among Iraq War Veterans. Am J Psychiatry 2007; 164: 150-153.
2. Marx BP: Posttraumatic stress disorder and Operations Enduring Freedom and Iraqi Freedom: Progress in a time of controversy. Clin Psychol Rev 2009; 1-3.
3. Dohrenwend BP, Turner B J, Turse NA, Adams BG, Koenen KC, Marshall R: The Psychological Risks of Vietnam for U.S. Veterans: A Revisit with New Data and Methods. Science 2006; 313: 979-982.
4. Basoglu M, Mineka S, Paker M, Aker T, Livanon M, Gök S: Psychological preparedness for trauma as a protective factor in survivors of torture. Psychol Med, 1997; 27(6): 1421-1433.
5. Minor TR, Dess, N.K., Overmier, JB: Inverting the traditional view of "learned helplessness", in Fear, avoidance, and phobias: A fundamental analysis. Edited by Denny MR, Hillsdale, N.J, Lawrence-Erlbaum Associates 1991, p. 87-133.
6. Minor TR, Hunter AM: Stressor controllability and learned helplessness research in the United States: sensitization and fatigue processes. Integr Physiol Behav Sci 2002; 37(1): p. 44-58.
7. American Psychological Association: Diagnostic and Statistical Manual of Mental Disorders (DSM-IV). 4th ed. Washington, DC: American Psychiatric Association, 1994.
8. Yehuda R: Post-Traumatic Stress Disorder. N Engl J Med 2002; 346(2): 108-114.
9. Ozer EJ, Best SR, Lipsey TL, Weiss DS: Predictors of posttraumatic stress disorder and symptoms in adults: A meta-analysis. Psychol Bull 2003; 129(1): 52-73.
10. Bisson JI: Post-traumatic stress disorder. BMJ (Clinical research ed. 2007; 334(7597): 789-93.
11. Hood SK, Carter MM. A: Preliminary Examination of Trauma History, Locus of Control, and PTSD Symptom Severity in African American Women. J Black Psychology 2008; 34(2): 179-191.
12. McNally RJ Progress and controversy in the study of posttraumatic stress disorder. Ann Review of Psychol 2003; 54: 229-52.
13. American Psychological Association: Diagnostic and Statistical Manual of Mental Disorders (DSM-IV), Criteria B. 4th ed. Washington, DC: American Psychiatric Association, 1994.
14. American Psychological Association: Diagnostic and Statistical Manual of Mental Disorders (DSM-IV), Criteria C. 4th ed. Washington, DC: American Psychiatric Association, 1994.
15. American Psychological Association: Diagnostic and Statistical Manual of Mental Disorders (DSM-IV), Criteria D 4th ed. Washington, DC: American Psychiatric Association, 1994.
16. Brady K T, Killeen T K, Brewerton T, Lucerini S: Comorbidity of Psychiatric Disorders and Posttraumatic Stress Disorder. J Clin Psychiatry 2000; 61: 22-32.
17. Pole N, Neylan TC, Otte C, Metzler TJ, Best SR, Henn-Haase C: Associations Between Childhood Trauma and Emotion-Modulated Psychophysiological Responses to Startling Sounds: A Study of Police Cadets. J Abnorm Psychol 2007; 116(2): 352- 361.
18. Kessler RC, DuPont RL, Berglund P, Wittchen HU: Impairment in pure and comorbid generalized anxiety disorder and Major depression at 12 months in two national surveys. Am J Psychiatry 1999; 156(2): 1915-23.
19. Kessler RC, Berglund P, Demler O, Jin R, Koretz D, Merikangas KR: The epidemiology of major depressive disorder: results from the National Comorbidity Survey Replication (NCS-R). J American Medical Association 2003; 289(23): 3095- 105.
20. Hasin DS, Goodwin RD, Stinson FS, Grant B: Epidemiology of major depressive disorder: results from the National Epidemiologic Survey on Alcoholism and Related Conditions 2005; Archives of general psychiatry 2005; 62(10): 1097-106.
21. Maier SF, Watkins L: Cytokines for psychologists: Implications of bidirectional immune-to-brain communication for understanding behavior, mood, and cognition. Psychological Review 1998; 105: 83-107.
22. Anisman H, Merali Z: Anhedonic and anxiogenic effects of cytokine exposure. Adv Exp Med Biol 1999; 461: 199-233.
23. Overmier JB, Hellhammer DH: The learned helplessness model of human depression, in An inquiry into schizophrenia and depression: Animal models of psychiatric disorders. Edited by Simon P, Soubrie P, Widlocher D. Basel, Switzerland, AG Karger, 1988.
24. Seligman ME: Learned Helplessness: On depression development and death. New York: W H Freeman, 1975.
25. Maier SF, Albin RW, Testa TJ: Failure to learn to escape in rats previously exposed to inescapable shock depends on the nature of the escape response. J Comp Physio Psych 1973; 85: 581-592.
26. Minor TR, LoLordo VM: Escape deficits following inescapable shock: the role of contextual odor. J Exp Psychol: Anim Beh Process 1984; 10:168-81.
27. Bolles RC, Fanselow MS: A perceptual-defensive-recuperative model of fear and pain. Behav Brain Sci 1980; 3: 291-323.
28. Maier SF: Role of fear in mediating shuttle escape learning deficit produced by inescapable shock. J Exp Psychol Anim Behav Process 1990; 16(2): 137-49.
29. Minor TR: Conditioned fear and neophobia following inescapable shock. Anim Learn Beh 1990; 18: 212-226.
30. Overmier JB, Seligman ME: Effects of inescapable shock upon subsequent escape and avoidance responding. J Comp Physiol Psychol 1967; 63(1): 28-33.
31. Minor TR, Trauner MA, Lee CY, Dess NK: Modeling signal features of escape response: effects of cessation conditioning in "learned helplessness" paradigm. J Exp Psychology Anim Behav Process 1990; 16: 123-136.
32. Mineka S, Cook M, Miller S: Fear conditioned with escapable and inescapable shock: effects of a feedback stimulus. J Exp Psych: Anim Behav Process 1984; 10: 307-324.
33. Rosellini RA, DeCola JP, Warren DA: The effects of feedback on contextual fear depends upon the minimum intertrial interval. Learning and Motivation 1986; 17: 229- 242.
34. Rosellini RA, DeCola JP, Warren DA: Predictability and controllability: Differential effects upon contextual fear. Learning and Motivation 1987; 18: 392-420.
35. Jackson RL, Minor TR: Effects of signaling inescapable shock on subsequent escape learning: implications for theories of coping and "learned helplessness". J Exp Psychol Anim Behav Process 1988; 14(4): 390-400.
36. Minor TR, Huang Q, Witt AE: Cytokine-purine interactions in traumatic stress, behavioral depression, and sickness. CSN & Neurological Disorders-Drug Targets 2006; 5(5): 547-560.
37. Simson PE, Weiss JM: Altered activity of the locus coeruleus in an animal model of depression. Neuropsychopharmacol 1988; 1: 287-295.
38. Anisman H, Remington G, Sklar LS: Effect of inescapable shock on subsequent escape performance: Catecholaminergic and cholinergic mediation of response initiation and maintenance. Psychopharmacol 1979; 61: 107-124.
39. Hunter AM, Balleine BW, Minor TR: Helplessness and escape performance: glutamate-adenosine interactions in the frontal cortex. Behav Neurosci 2003; 17(1): 123-135.
40. Minor TR, Pelleymounter MA, Maier SF: Uncontrollable shock, forebrain norepinephrine, and stimulus selection during choice-escape leaning. Psychobiology 1988; 16: 135-145.
41. Petty F, Sherman AD: Regional aspects of the prevention of learned helplessness by desiprimine. Life Sci 1980; 26: 1447-1452.
42. Anisman H, Zacharko RM: Behavioral and neurochemical consequences associated with stressors, in Stress-induced Analgesia. Edited by Kelly DD, Annals of the New York Academy of Sciences 1986; 467: 205-225.
43. Shors TJ, Servatius RJ: Stress-induced sensitization and facilitated learning require NMDA receptor activation. Neuroreport 1995; 6: 677-680.
44. Bodnar RJ, Kelly DD, Glusman M: 2-deoxy-D-glucose analgesia: influence of opiate and nonopiate factors. Pharmacol Biochem Behav1979; 21: 749-754.
45. Servatius RJ, Beck KD: Facilitated acquisition of the classically conditioned eyeblink response in male rats after systemic IL-1beta. Integr Physiol Behav Sci 2003; 38(3): 169-178.
46. Headrick JP, Bendall MR, Faden AI, Vink R: Dissociation of adenosine levels from bioenergetic state in experimental brain trauma: Potential role in secondary injury. J Cereb Blood Flow and Metab 1994; 14: 853-861.
47. Hoehn K, White TD: Role of excitatory amino acid receptors in K+ and glutamateevoked release of endogenous adenosine from rat cortical slices. J Neurochem 1990; 54: 256-265.
48. Lloyd HG, Lindstrom K, Fredholm BB: Intracellular formation and release of adenosine from rat hippocampal slices evoked by electrical stimulation or energy depletion. Neurochem Int 1993; 23: 173-185.
49. Newby AC: Adenosine and the concept of "retaliatory metabolites". Trends Biochem Sci 1984; 9: 42-44.
50. Stone TW: Physiological roles of adenosine and adenosine 5'triphosphate in the nervous system. Neurosci 1981; 6: 523-555.
51. Santos MS, Moreno AJ, Carvalho AP: Relationships between ATP depletion, membrane potential, and the release of neurotransmitters in rat nerve terminals. An in vitro study under conditions that mimic anoxia, hypoglycemia, and ischemia. Stroke 1996; 27(5): 941-950.
52. Weiner MF, Lovitt R: Conservation-withdrawal versus depression. Gen Hosp Psychiatry 1979; 1(4): 347-349.
53. Svenningsson P, Lindskog M, Rognoni F: Activation of adenosine A2A and dopamine D1 receptors stimulates cyclic AMP-dependent phosphorylation of DARPP-32 in distinct populations of striatal projection neurons. Neuroscience 1998;. 84(1): 223-228.
54. Bshesh K, Zhao B, Spight D: The A2A receptor mediates an endogenous regulatory pathway of cytokine expression in THP-1 cells. J Leukoc Biol 2002; 72(5): 1027-1036.
55. Rosin DL, Hettinger BD, Lee A, Linden J: Anatomy of adenosine A2A receptors in brain: morphological substrates for integration of striatal function. Neurology 2003; 61(11): 10-11.
56. Burnstock G: A basis for distinguishing two types of purinergic receptors. Cell Membrane Receptors for Drugs and Hormones 1978; 107-118.
57. Burnstock G: Pathophysiology and therapeutic potential of purinergic signaling. Pharmacol Rev 2006; 58(1): 58-86.
58. Burnstock G: Historical review: ATP as a neurotransmitter. Trends in Pharmocl Sci 2006; 27(3): 166-176.
59. Burnstock G: Purinergic signalling and disorders of the central nervous system. Nat Rev Drug Discov 2008; 7: 575-590.
60. Burnstock G, Verkhratsky A: Evolutionary origins of the purinergic signaling system. Acta Physiol (osf) 2009; 195(4): 415-417.
61. Gourine AV, Wood JD, Burnstock G: Purinergic signaling in autonomic control. Trends Neurosci 2009; 32(4): 241-248.
62. Gulbransen BD, Sharkey KA: Purinergic neuron-to-glia signaling in the enteric nervous system. Gastroenterolgy 2009; 136 94): 1349-1358.
63. Zimmermann J: Correspondence (letter to the editor): Brachytherapy is an Established Therapeutic Option. Dtsch Arztebl Int 2008; 105(50): 882.
64. Geiger JD, Fyda DM: Adenosine transport in nervous tissues, in Adenosine in the Central Nervous System. Edited by Stone TW, London, Academic Press 1991: 1-23.
65. Vorhoff t, Zimmermann H, Pelletier J, Sevigny J, Braun N: Cloning and characterization of the ecto-nucleotidases NTPDase3 from rat brain: Predicted secondary structure and relation to the other members of the E-NTPDase family and actin. Purinergic Signal 2005; 1(3): 259-270.
66. Sawada K, Echigo N, Juge N, Miyahi T, Otsuka M, Omote H, Yamamoto A, Moriyama Y. Proc Ntal Acad Sci USA 2008; 105(15): 5683-5686.
67. Yao J, Bajjalieh SM: SVOP is a nucleotide binding protein. PLoS One 2009; 4(4): 5315.
68. Burnstock G: Cotransmission. Curr Opin Pharmacol 2004; 4(1): 47-52.
69. Cunha RA, Sebastioa AM, Ribeiro JA: Inhibition of ATP of hippocampal synaptic transmission requires localized extracelllar catabolism by ecto-nucleotidases into adenosine and channeling to adenosine A1 receptors. J Neurosci 1998; 18(6): 1987-1985.
70. Dulla CG, Dobelis P, Pearson T, Frenguelli BG, Staley KJ, Masino SA: Adenosine and ATP link Pco2 to cortical excitability via pH. Neuron 2005; 48: 1011-1023.
71. Dunwiddie TV, Diao L, Proctor WR: Adenine nucleotides undergo rapid, quantitative conversion to adenosine in the extracellular space in rat hippocampus. J Neurosci 1997; 17(20): 7673-7682.
72. Langer d, Hammer K, Kosalka P, Schrader J, Robson S, Zimmermann H: Distribution of ectonucleotidases in the rodent brain revisited. Cell Tissue Res 2008; 334: 199-217.
73. Haas HL, Selbach O: Functions of neuronal adenosine receptors. Naunyn Schmiedebergs Arch Pharmacol 2000; 362(4-5): 375-381.
74. Phillis JW: Adenosine and adenine nucleotides as regulators of cerebral blood flow: Roles of acidosis, cell swelling, and KATP channels. Crit Rev Neurobiol 2004; 16(4): 237-270.
75. Linden J: Structure and function of A1 adenosine receptors. Faseb J 1991; 5(12): p. 2668-2676.
76. Bruns RF, Lu GH, Pugsley TA: Characterization of the A2 adenosine receptor labeled by [3H]NECA in rat striatal membranes. Mol Pharmacol 1986; 29(4): 331-46.
77. Sebastião AM, Ribeiro JA: Adenosine A2 receptor-mediated excitatory actions on the nervous system. Progress in Neurobiology 1996; 48: 167-189.
78. Calon F, Dridi M, Hornykiewicz O, Bédard PJ, Rajput AH, Di Paolo T: Increased adenosine A2A receptors in the brain of Parkinson's disease patients with dyskinesias. Brain 2004: 127(Pt 5): 1075-1084.
79. Svenningsson P, Le Moine C, Fisone G, Fredholm BB: Distribution, biochemistry and function of striatal adenosine A2A receptors. Prog Neurobiol 1999; 59(4): 355-396.
80. Ishiwata K, Mishina M, Kimura Y, Oda K, Sasaki T, Ishii K: First visualization of adenosine A(2A) receptors in the human brain by positron emission tomography with [11C]TMSX. Synapse 2005; 55(2): 133-136.
81. Mishina M, Ishiwata K, Kimura Y, Naganawa M, Oda K, Kobayashi S, Katayama Y, Ishii K: Evaluation of distribution of adenosine A2A receptors in normal human brain measured with [11C]TMSX PET. Synapse 2007; 61(9): 778-784.
82. Weaver DR: A2a adenosine receptor gene expression in developing rat brain. Brain Res Mol Brain Res 1993; 20(4): 313-327.
83. Castillo-Meléndez M, Krstew E, Lawrence AJ, Jarrott B: Presynaptic adenosine A2a receptors on soma and central terminals of rat vagal afferent neurons. Brain Res 1994; 652(1): 137-144.
84. Scislo TJ, O'Leary DS: Vasopressin V1 receptors contribute to hemodynamic and sympathoinhibitory responses evoked by stimulation of adenosine A2a receptors in NTS. Am J Physiol Heart Circ Physiol 2006; 290(5): 1889-1898.
85. Coleman CG, Baghdoyan HA, Lydic R: Dialysis delivery of an adenosine A2A agonist into the pontine reticular formation of C57BL/6J mouse increases pontine acetylcholine release and sleep. J Neurochem 2006; 96(6): 1750-1759.
86. Ferre S, Fredholm BB, Morelli M: Adenosine-dopamine receptor-receptor interactions as an integrative mechanism in the basal ganglia. Trends Neurosci 1997; 20(10): 482- 487.
87. Gessi S, Merighi S, Varani K, Leung E, Mac Lennan S, Borea PA: The A3 adenosine receptor: an enigmatic player in cell biology. Pharmacol Ther 2008; 117(1): 123-140.
88. Linden J, Taylor HE, Robeva AS, Tucker AL, Stehle JH, Rivkees SA, Fink JS, Reppert SM: Molecular cloning and functional expression of a sheep A3 adenosine receptor with widespread tissue distribution. Mol Pharmacol 1993; 44(3): 524-532.
89. Dantzer R: Cytokine-induced sickness behavior: where do we stand? Brain Behav Immun 2001; 15(1): 7-24.
90. Engel G L, Schmale AH: Conservation-withdrawal: A primary regulatory process for organismic homeostasis. Ciba Foundation Symposium 1972; 8: 57-75.
91. Mohta M, Sethi AK, Tyagi A: Psychological care in trauma patients. Injury 2003; 34(1): 17-25.
92. Weiner MF: Conservation-withdrawal and mental retardation in medical and surgical patients. Psychosomatics 1983; 24(1): 41-43.
93. Huang QJ, Jiang H, Hao XL, Minor TR: Brain IL-1 beta was involved in reserpineinduced behavioral depression in rats. Acta Pharmacol Sin 2004: 25(3): 293-296.
94. El Yacoubi M, Costentin J, Vaugeois JM: Adenosine A2A receptors and depression. Neurology 2003; 61(11 Suppl 6): 282-287.
95. Huang Q, Minor TR: Brain IL-1beta mediates reserpine-induced behavioral depression in rats. Chinese Journal of Behavioral and Medical Science 2003; 12(5): 491.
96. Kent S, Rodriguez F, Kelly KW, Dantzer R: Anorexia induced by microinjection of interleukin-1ß in the ventromedial hypothalamus of the rat. Physiol Beh 1994; 56: 1031-1036.
97. Milusheva E, Sperlagh, B, Kiss B, Szporny L, Pasztor E, Papasova M, Vizi ES: Inhibitory effect of hypoxic condition on acetylcholine release is partly due to the effect of adenosine release from tissue. Brain Research Bulletin 1990; 24: 369-373.
98. Burns RF: Role of adenosine in supply/demand balance. Nucleos Nucleotides 1991; 10: 931-933.
99. Ikemoto K: [Human striatal D-neurons and their significance]. Nihon Shinkei Seishin Yakurigaku Zasshi 2002; 22(4): 131-135.
100. Fuxe K, Agnati LF, Jacobsen K: Receptor heteromerization in adenosine A2A receptor signaling: relevance for striatal function and Parkinson's disease. Neurology 2003; 61(11 Suppl 6): 19-23.
101. Overmier JB, Hellhammer DH: The learned helplessness model of human depression, in An inquiry into schezophrenia and depression: Animal models of psychiatric disorders. Edited by Simon P, Soubrie P, Widlocher D. Basel, Switzerland, AG Karger, 1988.
102. Selye H: The general adaptation syndrome and the disease of adaptation. J Clin Endocr 1946; 6: 117.
103. Kern JA, Lamb RJ, Reed JC: Dexamethasone inhibition of interleukin 1 beta production by human monocytes. Posttranscriptional mechanisms. J Clin Invest 1988; 81(1): 237-244.
104. Hitchcock JM, Chaney SF, Zwolshen JM, Ketteler HJ, Peet NP, Soreson SM: Potential cognition-enhancing activity of the adenosine A1 receptor antagonist MDL 102,234 in spatial learning and long-term potentiation models. Society for Neuroscience Abstracts 1992; 18: 867.
105. White TD, Hoehn, K: Release of adenosine and ATP from nervous tissue, in Adenosine in the Nervous System. Edited by Stone TW. San Diego, CA, Academic Press, 1991, 173-196.
106. Maier SF, Watkins LR: Intracerebroventricular interleukin-1 receptor antagonist blocks the enhancement of fear conditioning and interference with escape produced by inescapable shock. Brain Research 1995: 695: 279-286.
107. Minor TR, Huang Q, Foley EA: Cytokine-purine interactions in behavioral depression in rats. Integr Physiol Behav Sci 2003; 38(3): 189-202.
108. Field TM: Coping with separation stress in infants and young children. In Stress and Coping. Edited by Fields TM, McCabe PM, Schneiderman N. Hillsdale, NJ, Lawrence Erlbaum Associates, 1985.
109. Avitsur R, Pollak Y, Yirmiya R: Administration of interleukin-1ß into the hypothalamic nucleus induces febrile and behavioral effects. Neuroimmunomodulation 1997; 4: 258-265.
110. Minor TR, Chang, WC, Winslow, JL: Stress and adenosine I: Effects of methylxanthine and amphetamine stimulants on learned helplessness in rats, Behav Neurosci 1994a; 108(2): 254-264.
111. Burnstock G: A basis for distinguishing two types of purinergic receptors. Cell Membrane Receptors for Drugs and Hormones 1978; 107-118.
112. Maier SF, Nguyen KT, Deak T: Stress, learned helplessness, and brain interleukin-1 beta. Adv Exp Med Biol 1999; 461: 235-249.
113. Field T, Reite M: Children's responses to separation from mother during the birth of another child. Child Dev, 1984; 55(4): 1308-1316.
114. Dragunow M: Purinergic mechanisms in epilepsy. Progress in Neurobiology 1988; 31: 154-158.
115. Daly JW: Adenosine agonists and antagonists. In Purines in cellular signaling: Targets for more drugs. Edited by Jacobs KA, Daly JW Manganiello V. New York, NY, Springer-Verlag, 1990.
116. Slisli Y, de Beaurepaire R: Interleukin-1beta and calcitonin, but not corticotropinreleasing factor, alter sleep cycles when injected into the rat hypothalamic lateral paraventricular area. Neurosci Lett 1999; 265(1): 29-32.
117. Hestad KA, Tonseth S, Stoen CD Ueland T, Aukrust P: Raised plasma levels of tumor necrosis factor alpha in patients with depression: normalization during electroconvulsive therapy. J ECT 2004; 19(4): 183-188.
118. Haung Q, Jiang H, Minor TR: Reserpine-induced depression in rats: Variations in brain intereukin-1ß define early versus late behavioral deficits. Biological Psychiatry, submitted.
119. Minor TR, Winslow JL, Chang WC: Stress and adenosine: II. Adenosine analogs mimic the effect of inescapable shock on shuttle-escape performance in rats. Behav Neurosci 1994b; 108(2): 265-276.
120. Minor TR, Dess NK, Ben-David E, Chang WC: Individual differences in vulnerability to inescapable shock in rats. J Experimental Psychol Anim Behav Process 1994b; 20: 402-412.
121. Arch RS, Newsholme EA: Activities and some properties of 5'-nucleotidase, adenosine kinase and adenosine deaminase in tissues from vertebrates and invertebrates in relation to the control of the concentration and the physiological role of adenosine. J Biochem 1978: 174: 965-977.
122. Geiger JD, Padua RA, Nagy JI: Adenosine deaminase regulation of purine actions. In J. W. Phillis (Ed.), Adenosine and adenine nucleotides as regulators of cellular function. Boca Raton, FL 1991; CRC Press: 71-84.
123. Newby AC: The interaction of inhibitors with adenosine metabolizing enzymes in intact isolated cells. Biochem Pharmacol 1981; 30: 2611-2615.
124. Noji T, Karasawa, A., Ksuka H: Adenosine uptake inhibitors. Eur J Pharmacol 2004; 495: 1-16.
125. Woodson JC, Minor TR, Job RF: Inhibition of adenosine deaminase by erythro-9-(2- hydroxy-3-nonyl)adenine (EHNA) mimics the effect of inescapable shock on escape learning in rats. Behav Neurosci 1998; 112(2): 399-409.
126. Minor TR, Rowe M, Cullen PK, Furst S: Enhancing brain adenosine signaling with the nucleoside transport blocker NBTI (S-(4-nitrobenzyl)-6-theoinosine) mimics the effects of inescapable shock on later shuttle-escape performance in rats. Behav Neurosci 2008; 122(6): 1236-1247.
127. Petty F, McChesney C, Kramer G: Intracortical glutamate injection produces helplesslike behavior in the rat. Pharmacol Biochem Behav 1985; 22(4): 531-533.
128. Nowak G, Trullas R, Layer RT, Skolnick P, Paul IA: Adaptive changes in the Nmethyl- D-aspartate receptor complex after chronic treatment with Imipramine and 1- aminocyclopropanecarboxylic acid. J Pharmacol Exp ther 1993; 265(3): 1380-1386.
129. Paul IA, Layer RT, Skolnick P, Nowak G: Adaptation of the NMDA receptor in rat cortex following chronic electroconvulsive shock or Imipramine. Eur J Pharmacol 1993; 147(3): 305-311.
130. Cassens G, Roffman M, Kuruc A: Alterations in brain norepinephrine metabolism induced by environmental stimuli previously paired with inescapable shock. Science 1980; 209(4461): 1138-1140.
131. Weiss JM, Goodman PA, Losito BG, Corrigan S, Charry JM, Bailey WH: Behavioral depression produced by an uncontrollable stressor: Relationship to norepinephrine, dopamine, and serotonin levels in various regions of rat brain. Brain Res Rev 1981; 3: 167-205.
132. Weiss JM, Simson PE: Mechanisms underlying stress-induced behavioral depression. In Stress and Coping. Edited by Field T, McCabe P, Schneiderman N. Hillsdale, Lawrence-Erlbaum Associates, 1985; 99-116.
133. Moghaddam B: Stress preferentially increases extraneuronal levels of excitatory amino acids in the prefrontal cortex: comparison to hippocampus and basal ganglia. J Neurochem 1993; 60(5): 1650-1657.
134. Bagley J, Moghaddam B: Temporla dynamics of glutamate efflux in the prefrontal cortex and in the hippocampus following repeated stress: effects of pretreatment with saline or diazepam. Neuroscience 1997; 77(1): 65-73.
135. Gilad GM, Gilad VH, Wyatt RJ, Tizabi Y: Region-selective stress-induced increase of glutamate uptake and release in rat forebrain. Brain Res 1990; 5252: 335-338.
136. Corda MG, Blaker WD, Mendelson WB, Guidotti A, Costa E: Beta-Carbolines enhance shock-induced suppression of drinking in rats. Proc Natl Acad Sci USA 1983; 80(7): 2072-2076.
137. Dorow R, Horowski R, Paschelke G, Amin M: Severe anxiety induced by FG 7142, a beta-carboline ligand for benzodiazepine receptors. Lancet 1983, 2(8341): 98-99.
138. Ongini e, Barzaghi C, Marzanatti M: Intrinsic and antagonistic effects of beta-carboline FG 7142 on behavioral and EEG actions of benzodiazepines and pentobarbital in cats. Eur J Phamarcol 1983, 95(1-2): 125-129.
139. Karreman M, Moghaddam B: Effect of pharmacological stress on glutamate efflux in the prefrontal cortex. Brain Res 1996; 716(1-2): 180-182.
140. Davis M, Walker DL, Lee Y: Neurophysiology and neuropharamocology of startle and its affective modulation, in Startle Modification. Edited by Dawson ME, Schell AM, Böhmelt, AH, United Kingdom, Cambridge University Press 1999: 95-113.
141. Davis TN: The centrosome on centre stage. Trends Cell Biol 1997.
142. Baxter, LR: Pet studies of cerebral function in major depression and obsessivecompulsive disorder: The emerging prefrontal cortex consensus. Annals of Clinical Psychiatry: The Official Journal of the American Academy of Clinical Psychiatrists 1991; 3(2): 103-109.
143. Soares JC, Mann: The functional neuroanatomy of mood disorders. J Psychiatr Res 1997; 31(4): 393-342.
144. Kishimoto H, Yamada K, Iseki E, Kosaka K & Okoshi T: Brain imagine of affective disorders and schizophrenia. Psychiatry Clin Neurosci 1998; 53 suppl: 212-214.
145. Nowak G, Ordway GA, Paul IA: Alterations in the N-methyl-D-aspartate (NMDA) receptor complex in the frontal cortex of suicide victims. Brain Res 1995; 675(1-2): 157-164.
146. Huang Q, Haoxingling, Minor TR: Reserpine increases brain IL-1beta expression in rat brain. Chinese Journal of Immunology 2003; 19(11): 765-767.
147. Albin RL, Young AB, Penney JB: The functional anatomy of basal ganglia disorders. Trends Neurosci 1989; 12: 366-375.
148. Heimer L, Wilson RD: The subcortical projections of the allocortex: similarities in the neural associations of the hippocampus, the piriform cortex, and the neocortex. In Golgi centennial symposium. Edited by Santinni M. New York, NY, Raven press, 1975, 177-193.
149. Kemp JM, and Powell TPS: The connexions of the striatum and globus pallidus: Synthesis and speculation. Phil Trans R Soc Lond 1971; 262(B): 441-457.
150. Herrero MT, Barcia C, Navarro JM: Functional anatomy of thalamus and basal ganglia. Childs Nerv Syst 2002; 18(8): 386-404.
151. Zaborszky L, Alheid GF, Beinfeld MC, Eiden LE, Heimer L, Palkovits M: Cholecystokinin innervation of the ventral striatum: a morphological and radioimmunological study. Neurosci 985; 14: 427-453.
152. Meredith GE, Baldo BA, Andrezjewski, ME, Kelley AE: The structural basis for mapping behavior onto the ventral striatum and its subdivisions. Brain Struct and Funct 2008; 213(1-2); 17-27.
153. Groenewegen HJ, Berendse HW, Meredith GE, Haber SN, Voorn P, Wolters JG, Lohman AHM: Functional anatomy of the ventral, limbic system-innervated striatum. In The mesolimbic dopamine system: from motivation to action. Edited by Willner P, Scheel-Krüger J. Chichester, Wiley, 1991, 19-59.
154. Ragsdale CW Jr, Graybiel AM: Fibers from the basolateral nucleus of the amygdale selectively innervate striosomes in the caudate nucleus of the cat. J Comp Neurol 1988; 269: 506-522.
155. Groenewegen HJ: The ventral striatum as an interface between the limbic and motor systems. CNS Spect 2007; 12(12): 887-892.
156. Corbit LH, Muir JL, Balleine BW: The role of the nucleus accumbens in instrumental conditioning: evidence of a functional dissociation between accumbens core and shell. J Neurosci 2001; 21: 3251-3260.
157. Parkinson JA, Olmstead MC, Burns LH, Robbins TW, Everitt BJ: Dissociation in effects of lesions of the nucleus accumbens core and shell on appetitive pavlovian approach behavior and the potentiation of conditioned reinforcement and locomotor activity by D-amphetamine. J eurosci 1999; 19: 2401-2411.
158. Alexander GE, Crutcher MD, DeLong MR: Basal ganglia-thalamocortical circuits: parallel substrates for motor, oculomotor, "prefrontal" and "limbic" functions. Prog Brain Res 1990; 85: 19-146.
159. Konorski J: Integrative activity of the brain: An interdisciplinary approach. University of Chicago Press, Chicago 1967.
160. Mogenson GJ, Jones DL, Yim CY: From motivation to action: Functional interface between the limbic system and the motor system. Prog Neurobiol 1980; 14: 69-97.
161. Graybiel AM: Input-output anatomy of the basal ganglia. In Symposium Lecture, Proc Soc Neurosci, Toronto, Canada 1976.
162. Ferré S, Diamond I, Goldberg SR, Yao L, Hourani SMO, Huang ZL, Urade Y, Kitchen I: Adenosine A2A receptors in ventral striatum, hypothalamus and nociceptive circuitry: Implications for drug addiction, sleep and pain. Prog Neurobiol 2007; 8: 332-347.
163. Schultz W: Getting formal with dopamine and reward. Neuron 2002; 36: 241-263.
164. Horvitz JC: Dopamine gating of glutamatergic sensorimotor and incentive motivational nput signals to the striatum. Behav Brain Res 2002; 137: 65-74.
165. Agnati LF, Ferre S, Lluis C, Franco R, Fuxe K: Molecular mechanisms and therapeutical implications of intramembrane receptor/receptor interactions among heptahelical receptors with examples from the striatopallidal GABA neurons. Pharmacol Rev 2003; 55: 509-550.
166. Ferre, S, Karcz-Kubicha M, Hope BT, Popoli P, Burgueno J, Gutierrez MA, Casado V, Fuxe K, Goldberg SR, Lluis C, Franco R, Ciruela F: Synergistic interaction between adenosine A2A and glutamate mGlu5 receptors: implications for striatal neuronal function. Proc Natl Acad Sci USA 2002; 99: 11940-11945.
167. Ferre,S, Borycz J, Goldberg SR, Hope BT, Morales M, Lluis C, Franco R, Ciruela F, Cunha R: Role of adenosine in the control of homosynaptic plasticity in striatal excitatory synapses. J Integr Neurosci 2005; 4: 445-464.
168. Anisman H, Sklar LS: Catecholamine depletion in mice upon reexposure to stress: mediation of the escape deficits produced by inescapable shock. J Comp Physiol Psychol 1979; 93: 610-625.