메뉴 건너뛰기




Volumn 9, Issue 3, 2014, Pages

DMH1, a small molecule inhibitor of BMP type I receptors, suppresses growth and invasion of lung cancer

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; BONE MORPHOGENETIC PROTEIN RECEPTOR 1; DMH1; SMAD1 PROTEIN; SMAD5 PROTEIN; SMAD8 PROTEIN; UNCLASSIFIED DRUG;

EID: 84897141192     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0090748     Document Type: Article
Times cited : (42)

References (24)
  • 2
    • 80052651609 scopus 로고    scopus 로고
    • Mechanisms of resistance to EGFR TKIs and development of a new generation of drugs in non-small-cell lung cancer
    • Kosaka T, Yamaki E, Mogi A, Kuwano H (2011) Mechanisms of resistance to EGFR TKIs and development of a new generation of drugs in non-small-cell lung cancer. J Biomed Biotechnol 2011: 165214.
    • (2011) J Biomed Biotechnol , vol.2011 , pp. 165214
    • Kosaka, T.1    Yamaki, E.2    Mogi, A.3    Kuwano, H.4
  • 3
    • 0037204990 scopus 로고    scopus 로고
    • Signal transduction by the TGF-beta superfamily
    • Attisano L, Wrana JL (2002) Signal transduction by the TGF-beta superfamily. Science 296: 1646-1647.
    • (2002) Science , vol.296 , pp. 1646-1647
    • Attisano, L.1    Wrana, J.L.2
  • 4
    • 21344455768 scopus 로고    scopus 로고
    • BMP receptor signaling: Transcriptional targets, regulation of signals, and signaling cross-talk
    • DOI 10.1016/j.cytogfr.2005.01.009, PII S1359610105000390
    • Miyazono K, Maeda S, Imamura T (2005) BMP receptor signaling: Transcriptional targets, regulation of signals, and signaling cross-talk. Cytokine & Growth Factor Reviews 16: 251-263. (Pubitemid 40910315)
    • (2005) Cytokine and Growth Factor Reviews , vol.16 , Issue.3 SPEC. ISS. , pp. 251-263
    • Miyazono, K.1    Maeda, S.2    Imamura, T.3
  • 5
    • 30944444113 scopus 로고    scopus 로고
    • Alterations in components of the TGF-beta superfamily signaling pathways in human cancer
    • DOI 10.1016/j.cytogfr.2005.09.009, PII S1359610105001139
    • Levy L, Hill CS (2006) Alterations in components of the TGF-beta superfamily signaling pathways in human cancer. Cytokine Growth Factor Rev 17: 41-58. (Pubitemid 43117515)
    • (2006) Cytokine and Growth Factor Reviews , vol.17 , Issue.1-2 , pp. 41-58
    • Levy, L.1    Hill, C.S.2
  • 6
    • 23944480887 scopus 로고    scopus 로고
    • Expression of bone morphogenetic proteins in human lung carcinomas
    • DOI 10.1016/j.athoracsur.2005.03.094, PII S0003497505005540
    • Langenfeld EM, Bojnowski J, Perone J, Langenfeld J (2005) Expression of bone morphogenetic proteins in human lung carcinomas. Annals of Thoracic Surgery 80: 1028-1032. (Pubitemid 41196808)
    • (2005) Annals of Thoracic Surgery , vol.80 , Issue.3 , pp. 1028-1032
    • Langenfeld, E.M.1    Bojnowski, J.2    Perone, J.3    Langenfeld, J.4
  • 7
    • 0141814613 scopus 로고    scopus 로고
    • The mature bone morphogenetic protein-2 is aberrantly expressed in non-small cell lung carcinomas and stimulates tumor growth of A549 cells
    • DOI 10.1093/carcin/bgg100
    • Langenfeld EM, Calvano SE, Abou-Nukta F, Lowry SF, Amenta P, et al. (2003) The mature bone morphogenetic protein-2 is aberrantly expressed in non-small cell lung carcinomas and stimulates tumor growth of A549 cells. Carcinogenesis 24: 1445-1454. (Pubitemid 37160834)
    • (2003) Carcinogenesis , vol.24 , Issue.9 , pp. 1445-1454
    • Langenfeld, E.M.1    Calvano, S.E.2    Abou-Nukta, F.3    Lowry, S.F.4    Amenta, P.5    Langenfeld, J.6
  • 8
    • 32244447227 scopus 로고    scopus 로고
    • Bone morphogenetic protein 2 stimulation of tumor growth involves the activation of Smad-1/5
    • DOI 10.1038/sj.onc.1209110, PII 1209110
    • Langenfeld EM, Kong Y, Langenfeld J (2006) Bone morphogenetic protein 2 stimulation of tumor growth involves the activation of Smad-1/5. Oncogene 25: 685-692. (Pubitemid 43214695)
    • (2006) Oncogene , vol.25 , Issue.5 , pp. 685-692
    • Langenfeld, E.M.1    Kong, Y.2    Langenfeld, J.3
  • 10
    • 80053202817 scopus 로고    scopus 로고
    • Effects of the Bone Morphogenetic Protein Binding Protein spp24 (Secreted Phosphoprotein 24 kD) on the Growth of Human Lung Cancer Cells
    • Lee KB, Murray SS, Duarte MEL, Spitz JF, Johnson JS, et al. (2011) Effects of the Bone Morphogenetic Protein Binding Protein spp24 (Secreted Phosphoprotein 24 kD) on the Growth of Human Lung Cancer Cells. Journal of Orthopaedic Research 29: 1712-1718.
    • (2011) Journal of Orthopaedic Research , vol.29 , pp. 1712-1718
    • Lee, K.B.1    Murray, S.S.2    Duarte, M.E.L.3    Spitz, J.F.4    Johnson, J.S.5
  • 11
    • 77449108244 scopus 로고    scopus 로고
    • In Vivo Structure-Activity Relationship Study of Dorsomorphin Analogues Identifies Selective VEGF and BMP Inhibitors
    • Hao J, Ho JN, Lewis JA, Karim KA, Daniels RN, et al. (2010) In Vivo Structure-Activity Relationship Study of Dorsomorphin Analogues Identifies Selective VEGF and BMP Inhibitors. Acs Chemical Biology 5: 245-253.
    • (2010) Acs Chemical Biology , vol.5 , pp. 245-253
    • Hao, J.1    Ho, J.N.2    Lewis, J.A.3    Karim, K.A.4    Daniels, R.N.5
  • 12
    • 84876081183 scopus 로고    scopus 로고
    • Bone morphogenetic protein type I receptor antagonists decrease growth and induce cell death of lung cancer cell lines
    • Langenfeld E, Hong CC, Lanke G, Langenfeld J (2013) Bone morphogenetic protein type I receptor antagonists decrease growth and induce cell death of lung cancer cell lines. PLoS One 8: e61256.
    • (2013) PLoS One , vol.8
    • Langenfeld, E.1    Hong, C.C.2    Lanke, G.3    Langenfeld, J.4
  • 13
    • 0036910425 scopus 로고    scopus 로고
    • Two major Smad pathways in TGF-beta superfamily signalling
    • DOI 10.1046/j.1365-2443.2002.00599.x
    • Miyazawa K, Shinozaki M, Hara T, Furuya T, Miyazono K (2002) Two major Smad pathways in TGF-beta superfamily signalling. Genes Cells 7: 1191-1204. (Pubitemid 36024597)
    • (2002) Genes to Cells , vol.7 , Issue.12 , pp. 1191-1204
    • Miyazawa, K.1    Shinozaki, M.2    Hara, T.3    Furuya, T.4    Miyazono, K.5
  • 15
    • 79960905179 scopus 로고    scopus 로고
    • Scratch-wound assay
    • Cory G (2011) Scratch-wound assay. Methods Mol Biol 769: 25-30.
    • (2011) Methods Mol Biol , vol.769 , pp. 25-30
    • Cory, G.1
  • 16
    • 54549102135 scopus 로고    scopus 로고
    • Bone morphogenetic protein signaling enhances invasion and bone metastasis of breast cancer cells through Smad pathway
    • Katsuno Y, Hanyu A, Kanda H, Ishikawa Y, Akiyama F, et al. (2008) Bone morphogenetic protein signaling enhances invasion and bone metastasis of breast cancer cells through Smad pathway. Oncogene 27: 6322-6333.
    • (2008) Oncogene , vol.27 , pp. 6322-6333
    • Katsuno, Y.1    Hanyu, A.2    Kanda, H.3    Ishikawa, Y.4    Akiyama, F.5
  • 17
    • 34547580553 scopus 로고    scopus 로고
    • Bone morphogenetic proteins and their receptor signaling in prostate cancer
    • Ye L, Lewis-Russell JM, Kyanaston HG, Jiang WG (2007) Bone morphogenetic proteins and their receptor signaling in prostate cancer. Histology and Histopathology 22: 1129-1147. (Pubitemid 47470307)
    • (2007) Histology and Histopathology , vol.22 , Issue.10-12 , pp. 1129-1147
    • Ye, L.1    Lewis-Russell, J.M.2    Kyanaston, H.G.3    Jiang, W.G.4
  • 18
    • 77953590859 scopus 로고    scopus 로고
    • Bone morphogenetic proteins in breast cancer: Dual role in tumourigenesis?
    • Alarmo EL, Kallioniemi A (2010) Bone morphogenetic proteins in breast cancer: dual role in tumourigenesis? Endocr Relat Cancer 17: R123-139.
    • (2010) Endocr Relat Cancer , vol.17
    • Alarmo, E.L.1    Kallioniemi, A.2
  • 19
    • 75749141315 scopus 로고    scopus 로고
    • Bone Morphogenetic Proteins and Cancer: Review of the Literature
    • Thawani JP, Wang AC, Than KD, Lin CY, La Marca F, et al. (2010) Bone Morphogenetic Proteins and Cancer: Review of the Literature. Neurosurgery 66: 233-246.
    • (2010) Neurosurgery , vol.66 , pp. 233-246
    • Thawani, J.P.1    Wang, A.C.2    Than, K.D.3    Lin, C.Y.4    La Marca, F.5
  • 20
    • 3543145020 scopus 로고    scopus 로고
    • Bone Morphogenetic Protein-2 stimulates angiogenesis in developing tumors
    • Langenfeld EM, Langenfeld J (2004) Bone morphogenetic protein-2 stimulates angiogenesis in developing tumors. Mol Cancer Res 2: 141-149. (Pubitemid 39030304)
    • (2004) Molecular Cancer Research , vol.2 , Issue.3 , pp. 141-149
    • Langenfeld, E.M.1    Langenfeld, J.2
  • 22
    • 84886150771 scopus 로고    scopus 로고
    • Small molecule antagonist of the bone morphogenetic protein type I receptors suppresses growth and expression of Id1 and Id3 in lung cancer cells expressing Oct4 or nestin
    • Langenfeld E, Deen M, Zachariah E, Langenfeld J (2013) Small molecule antagonist of the bone morphogenetic protein type I receptors suppresses growth and expression of Id1 and Id3 in lung cancer cells expressing Oct4 or nestin. Mol Cancer 12: 129.
    • (2013) Mol Cancer , vol.12 , pp. 129
    • Langenfeld, E.1    Deen, M.2    Zachariah, E.3    Langenfeld, J.4
  • 23
    • 84857657407 scopus 로고    scopus 로고
    • BMP activated Smad signaling strongly promotes migration and invasion of hepatocellular carcinoma cells
    • Maegdefrau U, Bosserhoff AK (2012) BMP activated Smad signaling strongly promotes migration and invasion of hepatocellular carcinoma cells. Exp Mol Pathol 92: 74-81.
    • (2012) Exp Mol Pathol , vol.92 , pp. 74-81
    • Maegdefrau, U.1    Bosserhoff, A.K.2
  • 24
    • 1642327586 scopus 로고    scopus 로고
    • Id-1 and Id-2 Proteins as Molecular Markers for Human Prostate Cancer Progression
    • DOI 10.1158/1078-0432.CCR-03-0933
    • Coppe JP, Itahana Y, Moore DH, Bennington JL, Desprez PY (2004) Id-1 and Id-2 proteins as molecular markers for human prostate cancer progression. Clin Cancer Res 10: 2044-2051. (Pubitemid 38375565)
    • (2004) Clinical Cancer Research , vol.10 , Issue.6 , pp. 2044-2051
    • Coppe, J.-P.1    Itahana, Y.2    Moore, D.H.3    Bennington, J.L.4    Desprez, P.-Y.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.