Nickel-induced cell death and survival pathways in cultured renal proximal tubule cells: Roles of reactive oxygen species, ceramide and ABCB1

Archives of Toxicology

Volumn 88, Issue 4, 2014, Pages 881-892

  Dahdouh, Faouzi ^a,b   Raane, Maximilian ^a   Thévenod, Frank ^a   Lee, Wing Kee ^a  

^a UNIVERSITY OF WITTEN HERDECKE   (Germany)

^b BADJI MOKHTAR UNIVERSITY   (Algeria)

Author keywords

Carcinogenesis; Kidney; ROS; Sphingolipid

Indexed keywords

ALPHA TOCOPHEROL; CARCINOGEN; CERAMIDE; CERAMIDE DERIVATIVE; CERAMIDE GLUCOSYLTRANSFERASE; CYCLOSERINE; DICHLORODIHYDROFLUORESCEIN DIACETATE; FUMONISIN B1; GLUCOSYLCERAMIDE; LIPID; MESSENGER RNA; MULTIDRUG RESISTANCE PROTEIN 1; NICKEL; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE 1; REACTIVE OXYGEN METABOLITE; SMALL INTERFERING RNA; VALSPODAR; XENOBIOTIC AGENT; ABCB1 PROTEIN, HUMAN; ENZYME INHIBITOR; GLUCOSYLTRANSFERASE; MULTIDRUG RESISTANCE PROTEIN; MULTIDRUG RESISTANCE PROTEIN 3; NICKEL CHLORIDE;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL PROTECTION; CELL STRESS; CELL SURVIVAL; CELL VIABILITY; CONTROLLED STUDY; DNA FRAGMENTATION; ENZYME INHIBITION; IMMUNOHISTOCHEMISTRY; KIDNEY PROXIMAL TUBULE; METABOLITE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN INDUCTION; SIGNAL TRANSDUCTION; UPREGULATION; ANIMAL; ANTAGONISTS AND INHIBITORS; DOG; DOSE RESPONSE; DRUG EFFECTS; GENETIC TRANSFECTION; GENETICS; HUMAN; MDCK CELL LINE; METABOLISM; OXIDATIVE STRESS; PATHOLOGY; RAT; RNA INTERFERENCE; TIME FACTOR;

ANIMALS; APOPTOSIS; CELL SURVIVAL; DOGS; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME INHIBITORS; GLUCOSYLCERAMIDES; GLUCOSYLTRANSFERASES; HUMANS; KIDNEY TUBULES, PROXIMAL; MADIN DARBY CANINE KIDNEY CELLS; NICKEL; OXIDATIVE STRESS; P-GLYCOPROTEINS; RATS; REACTIVE OXYGEN SPECIES; RNA INTERFERENCE; RNA, MESSENGER; SIGNAL TRANSDUCTION; TIME FACTORS; TRANSFECTION; UP-REGULATION;

EID: 84897115515     PISSN: 03405761     EISSN: 14320738     Source Type: Journal    
DOI: 10.1007/s00204-014-1194-x     Document Type: Article

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