Anti-melanoma activity of Cynanchi atrati Radix is mediated by regulation of NF-kappa B activity and pro-Apoptotic proteins

Journal of Ethnopharmacology

Volumn 153, Issue 1, 2014, Pages 250-257

  Son, Seung Wan ^a   Kim, Hyeong Geug ^b   Han, Jong Min ^b   Lee, Jin Seok ^b   Choi, Min Kyung ^b   Lee, Jong Seok ^c   Son, Chang Gue ^b  

^a Korea University   (South Korea)

^b Daejeon University   (South Korea)

^c Strategy and Planning Division   (South Korea)

Author keywords

Apoptosis; B16F10; Cynanchi Atrati Radix; Melanoma; Nuclear factor kappa B

Indexed keywords

4',6 DIAMIDINO 2 PHENYLINDOLE; ALCOHOL; CASPASE 3; CASPASE 7; CYNANCHI ATRATI EXTRACT; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; PLANT EXTRACT; PROTEIN BCL XL; PROTEIN P53; UNCLASSIFIED DRUG; ANTINEOPLASTIC AGENT; APOPTOSIS REGULATORY PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; ANTIPROLIFERATIVE ACTIVITY; APOPTOSIS; ARTICLE; BODY WEIGHT; CANCER SIZE; CELL PROLIFERATION; CELL PROLIFERATION ASSAY; CONTROLLED STUDY; CYNANCHI ATRATI; ENZYME ACTIVITY; ENZYME ASSAY; FLOW CYTOMETRY; GENE EXPRESSION; IMMUNOBLOTTING; MALE; MEDICINAL PLANT; MELANOMA; MOUSE; NICK END LABELING; NONHUMAN; SURVIVAL; SURVIVAL RATE; TANDEM MASS SPECTROMETRY; ULTRA PERFORMANCE LIQUID CHROMATOGRAPHY; WESTERN BLOTTING; ANIMAL; C57BL MOUSE; CHEMISTRY; CYNANCHUM; DOSE RESPONSE; DRUG EFFECTS; GENE EXPRESSION REGULATION; ISOLATION AND PURIFICATION; MELANOMA, EXPERIMENTAL; METABOLISM; PATHOLOGY; PLANT ROOT; SKIN NEOPLASMS; TUMOR CELL LINE; TUNEL ASSAY;

MUS;

ANIMALS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; APOPTOSIS; APOPTOSIS REGULATORY PROTEINS; CELL LINE, TUMOR; CELL PROLIFERATION; CYNANCHUM; DOSE-RESPONSE RELATIONSHIP, DRUG; FLOW CYTOMETRY; GENE EXPRESSION REGULATION, NEOPLASTIC; IN SITU NICK-END LABELING; MALE; MELANOMA, EXPERIMENTAL; MICE; MICE, INBRED C57BL; NF-KAPPA B; PLANT EXTRACTS; PLANT ROOTS; SKIN NEOPLASMS;

EID: 84897114960     PISSN: 03788741     EISSN: 18727573     Source Type: Journal    
DOI: 10.1016/j.jep.2014.02.037     Document Type: Article

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