The final step in the formation of 25S rRNA in saccharomyces cerevisiae is performed by 5' → 3' exonucleases

RNA

Volumn 6, Issue 12, 2000, Pages 1698-1703

  Geerlings, T H ^a   Vos, J C ^a   Raue, H A ^a  

^a VU UNIVERSITY AMSTERDAM   (Netherlands)

Author keywords

ITS2; Processing; Rat1p; Ribosomal RNA; Ribosome; Xrn1p

Indexed keywords

EXONUCLEASE; PHOSPHODIESTERASE I; PROTEIN SUBUNIT; RIBOSOME RNA; RNA 25S; RNA 5.8S; RNA PRECURSOR; SPLEEN EXONUCLEASE; UNCLASSIFIED DRUG;

ALLELE; ARTICLE; ENZYME ACTIVITY; ENZYME STRUCTURE; ENZYME SUBUNIT; NONHUMAN; PRIORITY JOURNAL; PROTEIN PROCESSING; PROTEIN SECONDARY STRUCTURE; REACTION ANALYSIS; RNA SYNTHESIS; SACCHAROMYCES CEREVISIAE; STRUCTURE ANALYSIS; YEAST;

BASE SEQUENCE; DNA, FUNGAL; DNA, INTERGENIC; EXORIBONUCLEASES; FUNGAL PROTEINS; MOLECULAR SEQUENCE DATA; RNA POLYMERASE I; RNA PRECURSORS; RNA PROCESSING, POST-TRANSCRIPTIONAL; RNA, FUNGAL; RNA, RIBOSOMAL; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS; TRANSCRIPTION, GENETIC;

SACCHAROMYCES CEREVISIAE;

EID: 0034548433     PISSN: 13558382     EISSN: None     Source Type: Journal    
DOI: 10.1017/S1355838200001540     Document Type: Article

References (35)

1. Isolation and characterization of RAT1: An essential gene of Saccharomyces cerevisiae required for the efficient nucleocytoplasmic trafficking of mRNA
2. Degradation of mRNA in eukaryotes
3. Identification and functional analysis of two U3 binding sites on yeast preribosomal RNA
4. Dbp10p, a putative RNA helicase from Saccharomyces cerevisiae, is required for ribosome biogenesis
5. Non-ribosomal nucleotide sequences in 7-S RNA, the immediate precursor of 5.8-S ribosomal RNA in yeast
6. Terminal nucleotide sequences of 17S ribosomal RNA and its immediate precursor 18S rRNA in yeast
7. Dob1p (Mtr4p) is a putative ATP-dependent RNA helicase required for the 3' end formation of 5.8S rRNA in Saccharomyces cerevisiae
8. Lithium toxicity in yeast is due to the inhibition of RNA processing enzymes
9. The 5' end of yeast 5.8S rRNA is generated by exonucleases from an upstream cleavage site
10. Rat1p and Xrn1p are functionally interchangeable exoribonucleases that are restricted to and required in the nucleus and cytoplasm, respectively
11. An essential yeast gene with homology to the endonuclease-encoding XRN1/KEM1 gene also encodes a protein with exoribonuclease activity
12. Protein trans-acting factors involved in ribosome biogenesis in Saccharomyces cerevisiae
13. Yeast Rnt1p is required for cleavage of the pre-ribosomal RNA in the 3' ETS but not the 5' ETS
14. Characterization of the XRN1 gene encoding a 5'-3' exoribonuclease: Sequence data and analysis of disparate protein and mRNA levels of genedisrupted yeast cells
15. Alternate pathways for processing in the Internal Transcribed Spacer 1 in pre-rRNA of Saccharomyces cerevisiae
16. Accurate processing of a eukaryotic precursor ribosomal RNA by ribonuclease MRP in vitro
17. The exosome - A conserved eukaryotic RNA processing complex containing multiple 3'-5' exoribonucleases
18. The 3' end of yeast 5.8S rRNA is generated by an exonuclease processing mechanism
19. Nuclear export of the small ribosomal subunit requires the Ran-GTPase cycle and certain nucleoporins
20. Processing of the precursors to small nucleolar RNAs and rRNAs requires common components
21. Seven novel methylation guide small nucleolar RNAs are processed from a common polycistronic transcript by Rat1p and RNase III in yeast
22. Nuclear RNase MRP is required for correct processing of pre-5.8S rRNA in Saccharomyces cerevisiae
23. Fragments of the Internal Transcribed Spacer 1 of pre-rRNA accumulate in Saccharomyces cerevisiae lacking 5' → 3' exoribonuclease-1
24. Maturation of ribosomal ribonudeic acid in yeast. Kinetic analysis of labeling of high molecular weight rRNA species
25. The cytoplasmic maturation of a ribosomal precursor ribonucleic acid in yeast
26. Functional analysis of internal transcribed spacer 2 of Saccharomyces cerevisiae ribosomal DNA
27. Three conserved members of the RNase D family have unique and overlapping functions in the processing of 5S, 5.8S, U4, U5, RNase MRP and RNase P RNAS in yeast
28. Evolutionary conserved structural elements are critical for processing of Internal Transcribed Spacer 2 from Saccharomyces cerevisiae
29. Some characteristics of processing sites in ribosomal precursor RNA of yeast
30. The nucleotide sequence of the intergenic region between the 5.8S and 26S rRNA genes of the yeast ribosomal RNA operon. Possible implications for the interaction between 5.8S and 26S rRNA and the processing of the primary transcript
31. Development and application of an in vivo system to study yeast ribosomal RNA biogenesis and function
32. Ribosome synthesis in Saccharomyces cerevisiae
33. Processing of the intron-encoded U18 small nucleolar RNAin the yeast Saccharomyces cerevisiae relies on both exo- and endonucleolytic activities
34. Saccharomyces cerevisiae RAI1 (YGL246c) is homologous to human DOM3Z and encodes a protein that binds the nuclear exoribonuclease Rat1p
35. Structural analysis of the Internal Transcribed Spacer 2 of the precursor ribosomal RNA from Saccharomyces cerevisiae