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Volumn 41, Issue 4, 2014, Pages 733-739

Point mutation of the xylose reductase (XR) gene reduces xylitol accumulation and increases citric acid production in Aspergillus carbonarius

Author keywords

Aspergillus carbonarius; Citric acid; Pentose catabolic pathway; Xylitol; Xylose fermentation; Xylose reductase

Indexed keywords

ARGININE; CITRIC ACID; LYSINE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE; XYLITOL; XYLOSE;

EID: 84897108287     PISSN: 13675435     EISSN: 14765535     Source Type: Journal    
DOI: 10.1007/s10295-014-1415-6     Document Type: Article
Times cited : (24)

References (42)
  • 3
    • 66749091546 scopus 로고    scopus 로고
    • Xylose reductase from Pichia stipitis with altered coenzyme preference improves ethanolic xylose fermentation by recombinant Saccharomyces cerevisiae
    • doi:10.1186/1754-6834-2-9
    • Bengtsson O, Hahn-Hägerdal B, Gorwa-Grauslund MF (2009) Xylose reductase from Pichia stipitis with altered coenzyme preference improves ethanolic xylose fermentation by recombinant Saccharomyces cerevisiae. Biotechnol Biofuels 2:9. doi:10.1186/1754-6834-2-9
    • (2009) Biotechnol Biofuels , vol.2 , pp. 9
    • Bengtsson, O.1    Hahn-Hägerdal, B.2    Gorwa-Grauslund, M.F.3
  • 4
    • 56449084752 scopus 로고    scopus 로고
    • Comparing the xylose reductase/xylitol dehydrogenase and xylose isomerase pathways in arabinose and xylose fermenting Saccharomyces cerevisiae strains
    • doi:10.1186/1754-6834-1-16
    • Bettiga M, Hahn-Hägerdal B, Gorwa-Grauslund MF (2008) Comparing the xylose reductase/xylitol dehydrogenase and xylose isomerase pathways in arabinose and xylose fermenting Saccharomyces cerevisiae strains. Biotechnol Biofuels 1:16. doi:10.1186/1754-6834-1-16
    • (2008) Biotechnol Biofuels , vol.1 , pp. 16
    • Bettiga, M.1    Hahn-Hägerdal, B.2    Gorwa-Grauslund, M.F.3
  • 5
    • 64749094343 scopus 로고    scopus 로고
    • Functional expression of a bacterial xylose isomerase in Saccharomyces cerevisiae
    • doi:10.1128/aem.02522-08
    • Brat D, Boles E, Wiedemann B (2009) Functional expression of a bacterial xylose isomerase in Saccharomyces cerevisiae. Appl Environ Microb 75(8):2304-2311. doi:10.1128/aem.02522-08
    • (2009) Appl Environ Microb , vol.75 , Issue.8 , pp. 2304-2311
    • Brat, D.1    Boles, E.2    Wiedemann, B.3
  • 6
    • 0021142327 scopus 로고
    • NADHlinked aldose reductase: The key to anaerobic alcoholic fermentation of xylose by yeasts
    • doi:10.1007/bf00251847
    • Bruinenberg PM, de Bot PHM, van Dijken JP (1984) NADHlinked aldose reductase: the key to anaerobic alcoholic fermentation of xylose by yeasts. Appl Microbiol Biot. doi:10.1007/bf00251847
    • (1984) Appl Microbiol Biot
    • Bruinenberg, P.M.1    De Bot, P.H.M.2    Van Dijken, J.P.3
  • 8
    • 0141428847 scopus 로고    scopus 로고
    • A semiquantitative PCR method (SQ-PCR) to measure Epstein-Barr virus (EBV) load: Its application in transplant patients
    • DOI 10.1016/S1386-6532(03)00077-5
    • Fellner MD, Durand K, Correa M, Bes D, Alonio LV, Teyssié AR, Picconi MA (2003) A semiquantitative PCR method (SQPCR) to measure Epstein-Barr virus (EBV) load: its application in transplant patients. J Clin Virol 28(3):323-330. doi:10.1016/S1386-6532(03)00077-5 (Pubitemid 37159373)
    • (2003) Journal of Clinical Virology , vol.28 , Issue.3 , pp. 323-330
    • Fellner, M.D.1    Durand, K.2    Correa, M.3    Bes, D.4    Alonio, L.V.5    Teyssie, A.R.6    Picconi, M.A.7
  • 9
    • 0026066008 scopus 로고
    • Study of xylitol formation from xylose under oxygen limiting conditions
    • Furlan SA, Bouilloud P, Strehaiano P, Riba JP (1991) Study of xylitol formation from xylose under oxygen limiting conditions. Biotechnol Lett 13(3):203-206
    • (1991) Biotechnol Lett , vol.13 , Issue.3 , pp. 203-206
    • Furlan, S.A.1    Bouilloud, P.2    Strehaiano, P.3    Riba, J.P.4
  • 10
    • 84870831090 scopus 로고    scopus 로고
    • New insight into the ochratoxin A biosynthetic pathway through deletion of a nonribosomal peptide synthetase gene in Aspergillus carbonarius
    • doi:10.1128/aem.02508-12
    • Gallo A, Bruno K, Solfrizzo M, Perrone G, Mulè G, Visconti A, Baker S (2012) New insight into the ochratoxin A biosynthetic pathway through deletion of a nonribosomal peptide synthetase gene in Aspergillus carbonarius. Appl Environ Microb 78(23):8208-8218. doi:10.1128/aem.02508-12
    • (2012) Appl Environ Microb , vol.78 , Issue.23 , pp. 8208-8218
    • Gallo, A.1    Bruno, K.2    Solfrizzo, M.3    Perrone, G.4    Mulè, G.5    Visconti, A.6    Baker, S.7
  • 12
    • 82455209009 scopus 로고    scopus 로고
    • Xylitol does not inhibit xylose fermentation by engineered Saccharomyces cerevisiae expressing xylA as severely as it inhibits xylose isomerase reaction in vitro
    • doi:10.1007/s00253-011-3345-9
    • Ha S-J, Kim S, Choi J-H, Park M, Jin Y-S (2011) Xylitol does not inhibit xylose fermentation by engineered Saccharomyces cerevisiae expressing xylA as severely as it inhibits xylose isomerase reaction in vitro. Appl Microbiol Biot 92(1):77-84. doi:10.1007/s00253-011-3345-9
    • (2011) Appl Microbiol Biot , vol.92 , Issue.1 , pp. 77-84
    • Ha, S.-J.1    Kim, S.2    Choi, J.-H.3    Park, M.4    Jin, Y.-S.5
  • 14
    • 84888019225 scopus 로고    scopus 로고
    • Advancing USER cloning into simpleUSER and nicking cloning
    • doi:10.1016/j.mimet.2013.10.018
    • Hansen NB, Lübeck M, Lübeck PS (2014) Advancing USER cloning into simpleUSER and nicking cloning. J Microbiol Methods 96:42-49. doi:10.1016/j.mimet.2013.10.018
    • (2014) J Microbiol Methods , vol.96 , pp. 42-49
    • Hansen, N.B.1    Lübeck, M.2    Lübeck, P.S.3
  • 16
    • 0034115471 scopus 로고    scopus 로고
    • The Aspergillus niger transcriptional activator XlnR, which is involved in the degradation of the polysaccharides xylan and cellulose, also regulates D-xylose reductase gene expression
    • DOI 10.1046/j.1365-2958.2000.01843.x
    • Hasper A, Visser J, de Graaff LH (2000) The Aspergillus niger transcriptional activator XlnR, which is involved in the degradation of the polysaccharides xylan and cellulose, also regulates d-xylose reductase gene expression. Mol Microbiol 36(1):193-200 (Pubitemid 30195401)
    • (2000) Molecular Microbiology , vol.36 , Issue.1 , pp. 193-200
    • Hasper, A.A.1    Visser, J.2    De Graaff, L.H.3
  • 17
    • 84897114129 scopus 로고    scopus 로고
    • Accessed 12 Feb 2012
    • Institute of Sciences of Food Production (2009) Agri-Food Toxigenic Fungi Culture Collection ITEM. http://server.ispa.cnr.it/ITEM/Collection/. Accessed 12 Feb 2012
    • (2009) Agri-Food Toxigenic Fungi Culture Collection ITEM
  • 18
    • 0020912407 scopus 로고
    • Utilization of xylose by bacteria, yeasts, and fungi
    • Jeffries TW (1983) Utilization of xylose by bacteria, yeasts, and fungi. Adv Biochem Eng Biotechnol 27:1-32
    • (1983) Adv Biochem Eng Biotechnol , vol.27 , pp. 1-32
    • Jeffries, T.W.1
  • 19
    • 0042371815 scopus 로고    scopus 로고
    • + and the basis for single and dual co-substrate specificity in family 2 aldo-keto reductases
    • DOI 10.1042/BJ20030286
    • Kavanagh KL, Klimacek M, Nidetzky B, Wilson DK (2003) Structure of xylose reductase bound to NAD+ and the basis for single and dual co-substrate specificity in family 2 aldo-keto reductases. Biochem J 373(Pt 2):319-326 (Pubitemid 36903204)
    • (2003) Biochemical Journal , vol.373 , Issue.2 , pp. 319-326
    • Kavanagh, K.L.1    Klimacek, M.2    Nidetzky, B.3    Wilson, D.K.4
  • 20
    • 12144288423 scopus 로고    scopus 로고
    • High-level functional expression of a fungal xylose isomerase: The key to efficient ethanolic fermentation of xylose by Saccharomyces cerevisiae?
    • DOI 10.1016/S1567-1356(03)00141-7, PII S1567135603001417
    • Kuyper M, Harhangi HR, Stave AK, Winkler A, Jetten MSM, de Laat WTAM, den Ridder JJJ, Op den Camp HJM, van Dijken JP, Pronk JT (2003) High-level functional expression of a fungal xylose isomerase: the key to efficient ethanolic fermentation of xylose by Saccharomyces cerevisiae? FEMS Yeast Res 4(1):69-78. doi:10.1016/S1567-1356(03)00141-7 (Pubitemid 38367533)
    • (2003) FEMS Yeast Research , vol.4 , Issue.1 , pp. 69-78
    • Kuyper, M.1    Harhangi, H.R.2    Stave, A.K.3    Winkler, A.A.4    Jetten, M.S.M.5    De Laat, W.T.A.M.6    Den, R.J.J.J.7    Op, D.C.H.J.M.8    Van Dijken, J.P.9    Pronk, J.T.10
  • 21
    • 1642315441 scopus 로고    scopus 로고
    • Minimal metabolic engineering of Saccharomyces cerevisiae for efficient anaerobic xylose fermentation: A proof of principle
    • DOI 10.1016/j.femsyr.2004.01.003, PII S156713560400011X
    • Kuyper M, Winkler A, van Dijken J, Pronk J (2004) Minimal metabolic engineering of Saccharomyces cerevisiae for efficient anaerobic xylose fermentation: a proof of principle. FEMS Yeast Res 4(6):655-664. doi:10.1016/j.femsyr.2004.01.003 (Pubitemid 38369140)
    • (2004) FEMS Yeast Research , vol.4 , Issue.6 , pp. 655-664
    • Kuyper, M.1    Winkler, A.A.2    Van Dijken, J.P.3    Pronk, J.T.4
  • 22
    • 0031826033 scopus 로고    scopus 로고
    • The structure and function of yeast xylose (aldose) reductases
    • .Lee H (1998) The structure and function of yeast xylose (aldose) reductases. Yeast 14(11):977-984
    • (1998) Yeast , vol.14 , Issue.11 , pp. 977-984
    • Lee, H.1
  • 23
    • 0142124355 scopus 로고    scopus 로고
    • Cloning and characterization of the xyl1 gene, encoding an NADH-preferring xylose reductase from Candida parapsilosis, and its functional expression in Candida tropicalis
    • doi:10.1128/aem.69.10.6179-6188.2003
    • .Lee JK, Koo BS, Kim SY (2003) Cloning and characterization of the xyl1 gene, encoding an NADH-preferring xylose reductase from Candida parapsilosis, and its functional expression in Candida tropicalis. Appl Environ Microb 69(10):6179-6188. doi:10.1128/aem.69.10.6179-6188.2003
    • (2003) Appl Environ Microb , vol.69 , Issue.10 , pp. 6179-6188
    • Lee, J.K.1    Koo, B.S.2    Kim, S.Y.3
  • 24
    • 12844288097 scopus 로고    scopus 로고
    • +
    • DOI 10.1016/j.febslet.2004.12.063, PII S0014579305000207
    • .Leitgeb S, Petschacher B, Wilson DK, Nidetzky B (2005) Fine tuning of coenzyme specificity in family 2 aldo-keto reductases revealed by crystal structures of the Lys-274->Arg mutant of Candida tenuis xylose reductase (AKR2B5) bound to NAD+ and NADP+. FEBS Lett 579(3):763-767. doi:10.1016/j. febslet.2004.12.063 (Pubitemid 40163998)
    • (2005) FEBS Letters , vol.579 , Issue.3 , pp. 763-767
    • Leitgeb, S.1    Petschacher, B.2    Wilson, D.K.3    Nidetzky, B.4
  • 25
    • 63949086429 scopus 로고    scopus 로고
    • Xylose isomerase from polycentric fungus Orpinomyces: Gene sequencing, cloning, and expression in Saccharomyces cerevisiae for bioconversion of xylose to ethanol
    • doi:10.1007/s00253-008-1794-6
    • Madhavan A, Tamalampudi S, Ushida K, Kanai D, Katahira S, Srivastava A, Fukuda H, Bisaria VS, Kondo A (2009) Xylose isomerase from polycentric fungus Orpinomyces: gene sequencing, cloning, and expression in Saccharomyces cerevisiae for bioconversion of xylose to ethanol. Appl Microbiol Biot 82(6):1067-1078. doi:10.1007/s00253-008-1794-6
    • (2009) Appl Microbiol Biot , vol.82 , Issue.6 , pp. 1067-1078
    • Madhavan, A.1    Tamalampudi, S.2    Ushida, K.3    Kanai, D.4    Katahira, S.5    Srivastava, A.6    Fukuda, H.7    Bisaria, V.S.8    Kondo, A.9
  • 26
    • 84858605128 scopus 로고    scopus 로고
    • Image analysis workflow for 2-D electrophoresis gels based on ImageJ
    • doi:10.4137/pri.s7971
    • .Natale M, Maresca B, Bucci PA, Enrico M (2011) Image analysis workflow for 2-D electrophoresis gels based on ImageJ. Proteomics Insights 4:37-49. doi:10.4137/pri.s7971
    • (2011) Proteomics Insights , vol.4 , pp. 37-49
    • Natale, M.1    Maresca, B.2    Bucci, P.A.3    Enrico, M.4
  • 27
    • 29844451427 scopus 로고    scopus 로고
    • Efficient PCR-based gene targeting with a recyclable marker for Aspergillus nidulans
    • DOI 10.1016/j.fgb.2005.09.005, PII S1087184505001398
    • .Nielsen ML, Albertsen L, Lettier G, Nielsen JB, Mortensen UH (2006) Efficient PCR-based gene targeting with a recyclable marker for Aspergillus nidulans. Fungal Genet Biol 43(1):54-64. doi:10.1016/j.fgb.2005.09.005 (Pubitemid 43038754)
    • (2006) Fungal Genetics and Biology , vol.43 , Issue.1 , pp. 54-64
    • Nielsen, M.L.1    Albertsen, L.2    Lettier, G.3    Nielsen, J.B.4    Mortensen, U.H.5
  • 28
    • 77956941760 scopus 로고    scopus 로고
    • USER cloning and USER fusion: The ideal cloning techniques for small and big laboratories
    • Plant secondary metabolism engineering: methods and applications. doi:10.1007/978-1-60761-723-5-13
    • .Nour-Eldin H, Geu-Flores F, Halkier BA (2010) USER cloning and USER fusion: the ideal cloning techniques for small and big laboratories. In: Plant secondary metabolism engineering: methods and applications. Methods Mol Biol 643:185-200. doi:10.1007/978-1-60761-723-5-13
    • (2010) Methods Mol Biol , vol.643 , pp. 185-200
    • Nour-Eldin, H.1    Geu-Flores, F.2    Halkier, B.A.3
  • 29
    • 33947635689 scopus 로고    scopus 로고
    • Advances in citric acid fermentation by Aspergillus niger: Biochemical aspects, membrane transport and modeling
    • doi:10.1016/j.biotechadv.2007.01.002
    • Papagianni M (2007) Advances in citric acid fermentation by Aspergillus niger: biochemical aspects, membrane transport and modeling. Biotechnol Adv 25(3):244-263. doi:10.1016/j.biotechadv.2007.01.002
    • (2007) Biotechnol Adv , vol.25 , Issue.3 , pp. 244-263
    • Papagianni, M.1
  • 30
    • 12844287005 scopus 로고    scopus 로고
    • The coenzyme specificity of Candida tenuis xylose reductase (AKR2B5) explored by site-directed mutagenesis and X-ray crystallography
    • DOI 10.1042/BJ20040363
    • Petschacher B, Leitgeb S, Kavanagh KL, Wilson DK, Nidetzky B (2005) The coenzyme specificity of Candida tenuis xylose reductase (AKR2B5) explored by site-directed mutagenesis and X-ray crystallography. Biochem J 385(Pt 1):75-83. doi:10.1042/BJ20040363 (Pubitemid 40164025)
    • (2005) Biochemical Journal , vol.385 , Issue.1 , pp. 75-83
    • Petschacher, B.1    Leitgeb, S.2    Kavanagh, K.L.3    Wilson, D.K.4    Nidetzky, B.5
  • 31
    • 42449145157 scopus 로고    scopus 로고
    • Altering the coenzyme preference of xylose reductase to favor utilization of NADH enhances ethanol yield from xylose in a metabolically engineered strain of Saccharomyces cerevisiae
    • doi:10.1186/1475-2859-7-9
    • Petschacher B, Nidetzky B (2008) Altering the coenzyme preference of xylose reductase to favor utilization of NADH enhances ethanol yield from xylose in a metabolically engineered strain of Saccharomyces cerevisiae. Microb Cell Fact 7:9. doi:10.1186/1475-2859-7-9
    • (2008) Microb Cell Fact , vol.7 , pp. 9
    • Petschacher, B.1    Nidetzky, B.2
  • 32
    • 34447250268 scopus 로고    scopus 로고
    • Construction of various mutants of xylose metabolizing enzymes for efficient conversion of biomass to ethanol
    • doi:10.1093/nass/nrl139
    • Saleh A, Watanabe S, Annaluru N, Kodaki T, Makino K (2006) Construction of various mutants of xylose metabolizing enzymes for efficient conversion of biomass to ethanol. Nucleic Acids Symp Ser 2004(50):279-280. doi:10.1093/nass/nrl139
    • (2006) Nucleic Acids Symp Ser , vol.2004 , Issue.50 , pp. 279-280
    • Saleh, A.1    Watanabe, S.2    Annaluru, N.3    Kodaki, T.4    Makino, K.5
  • 35
    • 0036159062 scopus 로고    scopus 로고
    • Hydrolysis of lignocellulosic materials for ethanol production: A review
    • DOI 10.1016/S0960-8524(01)00212-7, PII S0960852401002127
    • Sun Y, Cheng J (2002) Hydrolysis of lignocellulosic materials for ethanol production: a review. Bioresour Technol 83(1):1-11. doi:10.1016/s0960-8524(01) 00212-7 (Pubitemid 34126398)
    • (2002) Bioresource Technology , vol.83 , Issue.1 , pp. 1-11
    • Sun, Y.1    Cheng, J.2
  • 36
    • 0029589197 scopus 로고
    • Xylitol formation and key enzyme activities in Candida boidinii under different oxygen transfer rates
    • doi:10.1016/0922-338X(96)80929-9
    • Vandeska E, Kuzmanova S, Jeffries TW (1995) Xylitol formation and key enzyme activities in Candida boidinii under different oxygen transfer rates. J Ferment Bioeng 80(5):513-516. doi:10.1016/0922-338X(96)80929-9
    • (1995) J Ferment Bioeng , vol.80 , Issue.5 , pp. 513-516
    • Vandeska, E.1    Kuzmanova, S.2    Jeffries, T.W.3
  • 37
    • 85004271407 scopus 로고
    • Purification and characterization of xylose isomerase of a methanol yeast, Candida-Boidinii, which is involved in sorbitol production from glucose
    • Vongsuvanlert V, Tani Y (1988) Purification and characterization of xylose isomerase of a methanol yeast, Candida-Boidinii, which is involved in sorbitol production from glucose. Agr Biol Chem Tokyo 52(7):1817-1824
    • (1988) Agr Biol Chem Tokyo , vol.52 , Issue.7 , pp. 1817-1824
    • Vongsuvanlert, V.1    Tani, Y.2
  • 38
    • 0030772483 scopus 로고    scopus 로고
    • Expression of different levels of enzymes from the Pichia stipitis XYL1 and XYL2 genes in Saccharomyces cerevisiae and its effects on product formation during xylose utilisation
    • DOI 10.1007/s002530051041
    • Walfridsson M, Anderlund M, Bao X, Hahn-Hägerdal B (1997) Expression of different levels of enzymes from the Pichia stipitis XYL1 and XYL2 genes in Saccharomyces cerevisiae and its effects on product formation during xylose utilisation. Appl Microbiol Biot 48(2):218-224. doi:10.1007/s002530051041 (Pubitemid 27394753)
    • (1997) Applied Microbiology and Biotechnology , vol.48 , Issue.2 , pp. 218-224
    • Walfridsson, M.1    Anderlund, M.2    Bao, X.3    Hahn-Hagerdal, B.4
  • 39
    • 34948882785 scopus 로고    scopus 로고
    • Ethanol production from xylose by recombinant Saccharomyces cerevisiae expressing protein-engineered NADH-preferring xylose reductase from Pichia stipitis
    • DOI 10.1099/mic.0.2007/007856-0
    • Watanabe S, Abu Saleh A, Pack S, Annaluru N, Kodaki T, Makino K (2007) Ethanol production from xylose by recombinant Saccharomyces cerevisiae expressing protein-engineered NADH-preferring xylose reductase from Pichia stipitis. Microbiology 153(Pt 9):3044-3054. doi:10.1099/mic.0.2007/007856-0 (Pubitemid 47517065)
    • (2007) Microbiology , vol.153 , Issue.9 , pp. 3044-3054
    • Watanabe, S.1    Saleh, A.A.2    Pack, S.P.3    Annaluru, N.4    Kodaki, T.5    Makino, K.6
  • 40
    • 0001890167 scopus 로고    scopus 로고
    • Rapid procedure for the extraction of DNA from fungal spores and mycelia
    • Weiland JJ (2009) Rapid procedure for the extraction of DNA from fungal spores and mycelia. Fungal Genet Newsl 40:60-66
    • (2009) Fungal Genet Newsl , vol.40 , pp. 60-66
    • Weiland, J.J.1
  • 42
    • 84897107993 scopus 로고    scopus 로고
    • Fungal growth of Aspergillus carbonarius. Fungal growth database
    • Accessed 8 Sep 2013
    • Zhou M, De Vries RP, Wiebenga A, Robert V (2013) Fungal growth of Aspergillus carbonarius. Fungal growth database. BioloMICS Net. http://www.funggrowth.org/BioloMICS.aspx? Table = Fungal%20growth&Rec= 60&Fields=All. Accessed 8 Sep 2013
    • (2013) BioloMICS Net
    • Zhou, M.1    De Vries, R.P.2    Wiebenga, A.3    Robert, V.4


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