Lysophosphatidic acid induces vasodilation mediated by LPA1 receptors, phospholipase C, and endothelial nitric oxide synthase

FASEB Journal

Volumn 28, Issue 2, 2014, Pages 880-890

  Ruisanchez, Éva ^a   Dancs, Péter ^a   Kerék, Margit ^a   Németh, Tamás ^a   Faragó, Bernadett ^a   Balogh, Andrea ^b   Patil, Renukadevi ^b   Jennings, Brett L ^b   Liliom, Károly ^c   Malik, Kafait U ^b   Smrcka, Alan V ^d   Tigyi, Gabor ^b   Benyó, Zoltán ^a  

^a SEMMELWEIS UNIVERSITY   (Hungary)

^b UNIVERSITY OF TENNESSEE HEALTH SCIENCE CENTER   (United States)

^c INSTITUTE OF EXPERIMENTAL MEDICINE   (Hungary)

^d UNIVERSITY OF ROCHESTER   (United States)

Author keywords

Endothelium; ENOS; LPA; Phospholipase C; Vasorelaxation

Indexed keywords

1 [[6 (3 METHOXYESTRA 1,3,5(10) TRIEN 17BETA YL)AMINO]HEXYL] 1H PYRROLE 2,5 DIONE; 8 [4 (1 AMINOCYCLOBUTYL)PHENYL] 9 PHENYL 1,2,4 TRIAZOLO[3,4 F][1,6]NAPHTHYRIDIN 3(2H) ONE; EDELFOSINE; ENDOTHELIAL NITRIC OXIDE SYNTHASE; KI 16425; LYSOPHOSPHATIDIC ACID; LYSOPHOSPHATIDIC ACID 1 RECEPTOR; LYSOPHOSPHATIDIC ACID 2 RECEPTOR; LYSOPHOSPHATIDIC ACID 5 RECEPTOR; LYSOPHOSPHATIDIC ACID RECEPTOR; PHENYLEPHRINE; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHOLIPASE C; PROTEIN KINASE B; UNCLASSIFIED DRUG; VPC 31143; WORTMANNIN; LYSOPHOSPHOLIPID;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; ENDOTHELIUM; ENDOTHELIUM CELL; ENZYME INHIBITION; GENE DELETION; HUMAN; HUMAN CELL; INTRACELLULAR SIGNALING; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; THORACIC AORTA; VASOCONSTRICTION; VASODILATATION; ANIMAL; C57BL MOUSE; CELL CULTURE; DRUG EFFECT; ENOS; GENETICS; IN VITRO STUDY; KNOCKOUT MOUSE; LPA; METABOLISM;

ENDOTHELIUM; ENOS; LPA; PHOSPHOLIPASE C; VASORELAXATION;

ANIMALS; CELLS, CULTURED; ENDOTHELIAL CELLS; LYSOPHOSPHOLIPIDS; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; NITRIC OXIDE SYNTHASE TYPE III; RECEPTORS, LYSOPHOSPHATIDIC ACID; TYPE C PHOSPHOLIPASES; VASODILATION;

EID: 84897105499     PISSN: 08926638     EISSN: 15306860     Source Type: Journal    
DOI: 10.1096/fj.13-234997     Document Type: Article

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