Lysophosphatidic acid pretreatment prevents micromolar atorvastatin-induced endothelial cell death and ensures the beneficial effects of high-concentration statin therapy on endothelial gene expression

Annals of Vascular Surgery

Volumn 26, Issue 4, 2012, Pages 549-558

  Garrido, Jose M ^a   Esteban, Maria ^b   Roda, Olga ^c   Alaminos, Miguel ^c   Sánchez Montesinos, Indalecio ^c  

^a UNIVERSIDAD COMPLUTENSE DE MADRID   (Spain)

^b HOSPITAL UNIVERSITARIO VIRGEN DE LAS NIEVES   (Spain)

^c UNIVERSITY OF GRANADA   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

ATORVASTATIN; BETA4 INTEGRIN; CLAUDIN 5; ENDOTHELIAL NITRIC OXIDE SYNTHASE; ENDOTHELIN 1; LYSOPHOSPHATIDIC ACID; MICRORNA 21; OLIGONUCLEOTIDE; PROTEIN ZO1; VASCULAR ENDOTHELIAL CADHERIN; VASCULOTROPIN A; VASCULOTROPIN C; VASCULOTROPIN RECEPTOR 1;

ARTICLE; CELL ACTIVATION; CELL DEATH; CELL PROLIFERATION; CELL VIABILITY; CONTROLLED STUDY; ELECTRON PROBE MICROANALYSIS; ENDOTHELIUM CELL; GENE EXPRESSION; GENE EXPRESSION PROFILING; GENE REPRESSION; HUMAN; HUMAN CELL; MICROARRAY ANALYSIS; PRIORITY JOURNAL; UPREGULATION;

APOPTOSIS; CELL DEATH; CELL PROLIFERATION; CELL SURVIVAL; CELLS, CULTURED; DOSE-RESPONSE RELATIONSHIP, DRUG; ENDOTHELIN-1; GENE EXPRESSION REGULATION; HEPTANOIC ACIDS; HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS; HUMANS; HYDROXYMETHYLGLUTARYL-COA REDUCTASE INHIBITORS; LYSOPHOSPHOLIPIDS; NITRIC OXIDE SYNTHASE TYPE III; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PYRROLES; RNA;

EID: 84860236200     PISSN: 08905096     EISSN: 16155947     Source Type: Journal    
DOI: 10.1016/j.avsg.2012.01.005     Document Type: Article

References (35)

1. Z. Zhou, and J.K. Liao Pleiotropic effects of statins -basic research and clinical perspectives Cir J 74 2010 818 826
2. S. Muehlich, N. Schneider, and F. Hinkmann Induction of connective growth factor (CTGF) in human endothelial cells by lysophosphatidic acid, sphingosine-1-phosphate, and platelets Atherosclerosis 175 2004 261 268
3. S. Smyth, H. Cheng, and S. Miriyala Roles of lysophosphatidic acid in cardiovascular physiology and disease Biochim Biophys Acta 1781 2008 563 570
4. J.P. Desager, and Y. Horsmans Clinical pharmacokinetics of 3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitors Clin Pharmacokinetics 31 1996 348 371
5. J. Chen, and M.C. Wagner Altered membrane-cytoskeleton linkage and membrane blebbing in energy-depleted renal proximal tubular cells Am J Physiol Renal Physiol 280 2001 619 627
6. E. Fernandez-Segura, F.J. Cañizares, and M.A. Cubero Changes in elemental content during apoptotic cell death studied by electron probe X-ray microanalysis Exp Cell Res 253 1999 454 462
7. M. Alaminos, M.C. Sanchez-Quevedo, and J.I. Muñoz-Avila Evaluation of the viability of cultured corneal endothelial cells by quantitative electron probe X-ray microanalysis J Cell Physiol 211 2007 692 698
8. A. Rodriguez-Morata, I. Garzon, and M. Alaminos Cell viability and prostacyclin release in cultured human umbilical vein endothelial cells Ann Vasc Surg 22 2008 440 448
9. P.A. Clarke, R. Poele, and R. Wooster Gene expression microarrays analysis in cancer biology, pharmacology and drug development: progress and potential Biochem Pharmacol 62 2001 1311 1336
10. L.A. Boyer, K. Plath, and J. Zeitlinger Polycomb complexes repress developmental regulators in murine embryonic stem cells Nature 441 2006 349 353
11. A. Kulik, M.A. Brookhart, and R. Levin Impact of statin use on outcomes after coronary artery bypass graft surgery Circulation 118 2008 1785 1792
12. N. Hibino, E. McGillicuddy, and G. Matsumura Late-term results of tissue-engineered vascular grafts in humans J Thorac Cardiovasc Surg 139 2010 431 436
13. J.A. De Lemos, D.A. Morrow, and M.S. Sabatine Association between plasma levels of monocyte chemoattractant protein-1 and long-term clinical outcomes in patients with acute coronary syndromes Circulation 107 2003 690 695
14. J. Mason, Z. Ahmed, and R. Mankoff Statin-induced expression of decay-accelerating factor protects vascular endothelium against complement-mediated injury Cir Res 91 2002 696 703
15. M. Weis, C. Heeschen, and A.J. Glassford Statins have biphasic effects on angiogenesis Circulation 105 2002 739 745
16. R. Takata, S. Fukasawa, and T. Hara Cerivastatin-induced apoptosis of human aortic smooth muscle cells through partial inhibition of basal activation of extracellular signal-regulated kinases Cardiovasc Pathol 13 2004 41 48
17. I. Aprigliano, J. Dudas, and G. Ramadori Atorvastatin induces apoptosis by a caspase-9-dependent pathway: an in vitro study on activated rat stellate cells Liver Int 28 2008 546 557
18. N. Niknejad, M. Morley, and J. Dimitroulakos Activation of the integrated stress response regulates lovastatin-induces apoptosis J Biol Chem 282 2007 29748 29756
19. G.M. Roomans X-ray microanalysis of ephitelial cells in culture Methods Mol Biol 188 2002 273 289
20. H. Liu, S.L. Liang, and S. Kumar Statins induce apoptosis in ovarian cancer cells through activation of JNK and enhancement of Bim expression Cancer Chemother Pharmacol 63 2009 997 1005
21. J. Woodard, A. Sassano, and N. Hay Statin-dependent suppression of the AKT/mammalian target of rapamycin signalling cascade and programmed cell death 4 up-regulation in renal carcinoma Clin Cancer Res 14 2008 4640 4649
22. S. Stein, E.K. Thomas, and B. Herzog NDRG1 is necessary for p53-dependent apoptosis J Biol Chem 279 2004 48930 48940
23. T. Tanaka, S. Ohkubo, and I. Tatsuno Hcas/cse1L associates with chromatin and regulates expression of select p53 target genes Cell 130 2007 638 650
24. X. Li, H. Wei, and X. Liu LPA rescues ER stress-associated apoptosis in hypoxia and serum deprivation-stimulated mesenchymal stem cells J Cell Biochem 111 2010 811 820
25. Y. Sun, J.S. Nam, and D.H. Han Lysophosphatidic acid induces upregulation of Mcl-1 and protects apoptosis in a PTX-dependent manner in H19-7 cells Cell Signal 22 2010 484 494
26. M.J. Karkkainen, P. Hiko, and K. Sainio Vascular endothelial growth factor C is required for sprouting of the first lymphatic vessels from embryonic veins Nat Immunol 5 2004 11 12
27. A. Hoque, H. Chen, and X.C. Xu Statin induces apoptosis and cell growth arrest in prostate cancer cells Cancer Epidemiol Biomarkers Prev 17 2008 88 94
28. N. Kipshidze, M. Dangas, and J. Tsapenko Role of the endothelium in modulating neointimal formation: vasculoprotective approaches to attenuate restenosis after percutaneous coronary interventions J Am Coll Cardiol 44 2004 733 739
29. P. Zilla, D. Bezuidenhout, and P. Human Prosthetic vascular grafts: wrong models, wrong questions and no healing Biomaterials 28 2007 5009 5027
30. K.K. Farh, A. Grimson, and C. Jan The widespread impact of mammalian microRNAs on mRNA repression and evolution Science 310 2005 1817 1821
31. J.S. Ross, N.E. Stagliano, and M.J. Donovan Atherosclerosis: a cancer of the blood vessels? Am J Clin Pathol 16 2001 S97 S107
32. R. Ji, Y. Cheng, and J. Yue MicroRNA expression signature and antisense-mediated depletion reveal an essential role of microRNA in vascular neointimal lesion formation Cir Res 100 2007 1579 1588
33. N. L'Heureux, T.N. McAllister, and L.M. de la Fuente Tissue-engineered blood vessel for adult arterial revascularization N Eng J Med 357 2007 1451 1453
34. S.K. Yazdani, B.W. Tillman, and J.L. Berry The fate of an endothelium layer after preconditioning J Vasc Surg 51 2010 174 183
35. J.E. Stasek, C.E. Patterson, and J.G. Garcia Protein kinase C phosphorylates caldesmon77 and vimentin and enhances albumin permeability across cultured bovine pulmonary artery endothelial cell monolayers J Cell Physiol 153 1992 62 75