메뉴 건너뛰기




Volumn 12, Issue 3, 2014, Pages 194-198

Effect of Trifolium pratense extract on methionine-choline-deficient diet-induced steatohepatitis in C57BL/6 mice

Author keywords

Hepatic steatosis; Liver inflammation; Peroxisome proliferator activated receptor ; Steatohepatitis; Trifolium pratense

Indexed keywords

ACETYL COENZYME A; CARNITINE PALMITOYLTRANSFERASE I; CHOLESTEROL; CHOLINE; EOSIN; FATTY ACID BINDING PROTEIN; HEMATOXYLIN; LIPID; METHIONINE; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA; RED CLOVER EXTRACT; TRIACYLGLYCEROL; MESSENGER RNA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PLANT EXTRACT;

EID: 84897084422     PISSN: 20956975     EISSN: 18755364     Source Type: Journal    
DOI: 10.1016/S1875-5364(14)60032-7     Document Type: Article
Times cited : (10)

References (26)
  • 1
    • 0019152816 scopus 로고
    • Nonalcoholic steatohepatitis: Mayo Clinic experiences with a hitherto unnamed disease [J]
    • Ludwig J, Viggiano TR, McGill DB, et al. Nonalcoholic steatohepatitis: Mayo Clinic experiences with a hitherto unnamed disease [J]. Mayo Clin Proc 1980, 55(7):434-438.
    • (1980) Mayo Clin Proc , vol.55 , Issue.7 , pp. 434-438
    • Ludwig, J.1    Viggiano, T.R.2    McGill, D.B.3
  • 2
    • 79959466159 scopus 로고    scopus 로고
    • Current therapeutic strategies in non-alcoholic fatty liver disease [J]
    • Dowman JK, Armstrong MJ, Tomlinson JW, et al. Current therapeutic strategies in non-alcoholic fatty liver disease [J]. Diabetes Obes Metab 2011, 13(8):692-702.
    • (2011) Diabetes Obes Metab , vol.13 , Issue.8 , pp. 692-702
    • Dowman, J.K.1    Armstrong, M.J.2    Tomlinson, J.W.3
  • 3
    • 84862777613 scopus 로고    scopus 로고
    • Isoflavones as a smart curer for non-alcoholic fatty liver disease and pathological adiposity via ChREBP and Wnt signaling [J]
    • Kim MH, Kang KS Isoflavones as a smart curer for non-alcoholic fatty liver disease and pathological adiposity via ChREBP and Wnt signaling [J]. Prev Med 2012, 54(Suppl):S57-63.
    • (2012) Prev Med , vol.54 , Issue.SUPPL
    • Kim, M.H.1    Kang, K.S.2
  • 4
    • 0036848252 scopus 로고    scopus 로고
    • Role of soy isoflavones in the hypotriglyceridemic effect of soy protein in the rat [J]
    • Demonty I, Lamarche B, Deshaies Y, et al. Role of soy isoflavones in the hypotriglyceridemic effect of soy protein in the rat [J]. J Nutr Biochem 2002, 13(11):671-677.
    • (2002) J Nutr Biochem , vol.13 , Issue.11 , pp. 671-677
    • Demonty, I.1    Lamarche, B.2    Deshaies, Y.3
  • 5
    • 78149482135 scopus 로고    scopus 로고
    • The inhibitory effect of genistein on hepatic steatosis is linked to visceral adipocyte metabolism in mice with diet-induced non-alcoholic fatty liver disease [J]
    • Kim MH, Kang KS, Lee YS The inhibitory effect of genistein on hepatic steatosis is linked to visceral adipocyte metabolism in mice with diet-induced non-alcoholic fatty liver disease [J]. Br J Nutr 2010, 104(9):1333-1342.
    • (2010) Br J Nutr , vol.104 , Issue.9 , pp. 1333-1342
    • Kim, M.H.1    Kang, K.S.2    Lee, Y.S.3
  • 6
    • 80051598136 scopus 로고    scopus 로고
    • Daidzein supplementation prevents non-alcoholic fatty liver disease through alternation of hepatic gene expression profiles and adipocyte metabolism [J]
    • Kim MH, Park JS, Jung JW, et al. Daidzein supplementation prevents non-alcoholic fatty liver disease through alternation of hepatic gene expression profiles and adipocyte metabolism [J]. Int J Obes (Lond) 2011, 35(8):1019-1030.
    • (2011) Int J Obes (Lond) , vol.35 , Issue.8 , pp. 1019-1030
    • Kim, M.H.1    Park, J.S.2    Jung, J.W.3
  • 7
    • 33747175979 scopus 로고    scopus 로고
    • Effects of dietary genistein on hepatic lipid metabolism and mitochondrial function in mice fed high-fat diets [J]
    • Lee YM, Choi JS, Kim MH, et al. Effects of dietary genistein on hepatic lipid metabolism and mitochondrial function in mice fed high-fat diets [J]. Nutrition 2006, 22(9):956-964.
    • (2006) Nutrition , vol.22 , Issue.9 , pp. 956-964
    • Lee, Y.M.1    Choi, J.S.2    Kim, M.H.3
  • 8
    • 77955056005 scopus 로고    scopus 로고
    • Genistein improves liver function and attenuates non-alcoholic fatty liver disease in a rat model of insulin resistance [J]
    • Mohamed Salih S, Nallasamy P, Muniyandi P, et al. Genistein improves liver function and attenuates non-alcoholic fatty liver disease in a rat model of insulin resistance [J]. J Diabetes 2009, 1(4):278-287.
    • (2009) J Diabetes , vol.1 , Issue.4 , pp. 278-287
    • Mohamed Salih, S.1    Nallasamy, P.2    Muniyandi, P.3
  • 9
    • 84865355087 scopus 로고    scopus 로고
    • Red clover extract exerts antidiabetic and hypolipidemic effects in db/db mice [J]
    • Qiu L, Chen T, Zhong F, et al. Red clover extract exerts antidiabetic and hypolipidemic effects in db/db mice [J]. Exp Ther Med 2012, 4(4):699-704.
    • (2012) Exp Ther Med , vol.4 , Issue.4 , pp. 699-704
    • Qiu, L.1    Chen, T.2    Zhong, F.3
  • 10
    • 77949405407 scopus 로고    scopus 로고
    • Red clover extract: a source for substances that activate peroxisome proliferator- activated receptor alpha and ameliorate the cytokine secretion profile of lipopolysaccharide-stimulated macrophages [J]
    • Mueller M, Hobiger S, Jungbauer A Red clover extract: a source for substances that activate peroxisome proliferator- activated receptor alpha and ameliorate the cytokine secretion profile of lipopolysaccharide-stimulated macrophages [J]. Menopause 2010, 17(2):379-387.
    • (2010) Menopause , vol.17 , Issue.2 , pp. 379-387
    • Mueller, M.1    Hobiger, S.2    Jungbauer, A.3
  • 11
    • 84855243116 scopus 로고    scopus 로고
    • Biochanin A ameliorates the cytokine secretion profile of lipopolysaccharide-stimulated macrophages by a PPARgamma-dependent pathway [J]
    • Qiu L, Lin B, Lin Z, et al. Biochanin A ameliorates the cytokine secretion profile of lipopolysaccharide-stimulated macrophages by a PPARgamma-dependent pathway [J]. Mol Med Report 2012, 5(1):217-222.
    • (2012) Mol Med Report , vol.5 , Issue.1 , pp. 217-222
    • Qiu, L.1    Lin, B.2    Lin, Z.3
  • 12
    • 84861810610 scopus 로고    scopus 로고
    • Red clover extract ameliorates dyslipidemia in streptozotocin-induced diabetic C57BL/6 mice by activating hepatic PPARalpha [J]
    • Qiu L, Ye H, Chen L, et al. Red clover extract ameliorates dyslipidemia in streptozotocin-induced diabetic C57BL/6 mice by activating hepatic PPARalpha [J]. Phytother Res 2012, 26(6):860-864.
    • (2012) Phytother Res , vol.26 , Issue.6 , pp. 860-864
    • Qiu, L.1    Ye, H.2    Chen, L.3
  • 13
    • 11144310564 scopus 로고    scopus 로고
    • An overview on biological mechanisms of PPARs [J]
    • Kota BP, Huang TH, Roufogalis BD An overview on biological mechanisms of PPARs [J]. Pharmacol Res 2005, 51(2):85-94.
    • (2005) Pharmacol Res , vol.51 , Issue.2 , pp. 85-94
    • Kota, B.P.1    Huang, T.H.2    Roufogalis, B.D.3
  • 14
    • 2342644813 scopus 로고    scopus 로고
    • Administration of the potent PPARalpha agonist, Wy-14,643, reverses nutritional fibrosis and steatohepatitis in mice [J]
    • Ip E, Farrell G, Hall P, et al. Administration of the potent PPARalpha agonist, Wy-14,643, reverses nutritional fibrosis and steatohepatitis in mice [J]. Hepatology 2004, 39(5):1286-1296.
    • (2004) Hepatology , vol.39 , Issue.5 , pp. 1286-1296
    • Ip, E.1    Farrell, G.2    Hall, P.3
  • 15
    • 0038643427 scopus 로고    scopus 로고
    • Central role of PPARalpha-dependent hepatic lipid turnover in dietary steatohepatitis in mice [J]
    • Ip E, Farrell GC, Robertson G, et al. Central role of PPARalpha-dependent hepatic lipid turnover in dietary steatohepatitis in mice [J]. Hepatology 2003, 38(1):123-l132.
    • (2003) Hepatology , vol.38 , Issue.1
    • Ip, E.1    Farrell, G.C.2    Robertson, G.3
  • 16
    • 0034092716 scopus 로고    scopus 로고
    • CYP2E1 and CYP4A as microsomal catalysts of lipid peroxides in murine nonalcoholic steatohepatitis [J]
    • Leclercq IA, Farrell GC, Field J, et al. CYP2E1 and CYP4A as microsomal catalysts of lipid peroxides in murine nonalcoholic steatohepatitis [J]. J Clin Invest 2000, 105(8):1067-1075.
    • (2000) J Clin Invest , vol.105 , Issue.8 , pp. 1067-1075
    • Leclercq, I.A.1    Farrell, G.C.2    Field, J.3
  • 17
    • 0035083842 scopus 로고    scopus 로고
    • Nonalcoholic steatohepatitis: definition and pathology [J]
    • Brunt EM Nonalcoholic steatohepatitis: definition and pathology [J]. Semin Liver Dis 2001, 21(1):3-16.
    • (2001) Semin Liver Dis , vol.21 , Issue.1 , pp. 3-16
    • Brunt, E.M.1
  • 18
    • 18144411278 scopus 로고    scopus 로고
    • Phytoestrogens derived from red clover: an alternative to estrogen replacement therapy? [J]
    • Beck V, Rohr U, Jungbauer A Phytoestrogens derived from red clover: an alternative to estrogen replacement therapy? [J]. J Steroid Biochem Mol Biol 2005, 94(5):499-518.
    • (2005) J Steroid Biochem Mol Biol , vol.94 , Issue.5 , pp. 499-518
    • Beck, V.1    Rohr, U.2    Jungbauer, A.3
  • 19
    • 34547650833 scopus 로고    scopus 로고
    • Effects of dietary red clover on blood factors and cardiovascular fatty streak formation in hypercholesterolemic rabbits [J]
    • Asgary S, Moshtaghian J, Naderi G, et al. Effects of dietary red clover on blood factors and cardiovascular fatty streak formation in hypercholesterolemic rabbits [J]. Phytother Res 2007, 21(8):768-770.
    • (2007) Phytother Res , vol.21 , Issue.8 , pp. 768-770
    • Asgary, S.1    Moshtaghian, J.2    Naderi, G.3
  • 20
    • 33746596198 scopus 로고    scopus 로고
    • Soy and red clover for mid-life and aging [J]
    • Geller SE, Studee L Soy and red clover for mid-life and aging [J]. Climacteric 2006, 9(4):245-263.
    • (2006) Climacteric , vol.9 , Issue.4 , pp. 245-263
    • Geller, S.E.1    Studee, L.2
  • 21
    • 24744441935 scopus 로고    scopus 로고
    • Clinical effects of a proprietary combination isoflavone nutritional supplement in menopausal women: a pilot trial [J]
    • Lukaczer D, Darland G, Tripp M, et al. Clinical effects of a proprietary combination isoflavone nutritional supplement in menopausal women: a pilot trial [J]. Altern Ther Health Med 2005, 11(5):60-65.
    • (2005) Altern Ther Health Med , vol.11 , Issue.5 , pp. 60-65
    • Lukaczer, D.1    Darland, G.2    Tripp, M.3
  • 22
    • 2942695953 scopus 로고    scopus 로고
    • Effect of isoflavones on lipids and bone turnover markers in menopausal women [J]
    • Schult TM, Ensrud KE, Blackwell T, et al. Effect of isoflavones on lipids and bone turnover markers in menopausal women [J]. Maturitas 2004, 48(3):209-218.
    • (2004) Maturitas , vol.48 , Issue.3 , pp. 209-218
    • Schult, T.M.1    Ensrud, K.E.2    Blackwell, T.3
  • 23
    • 33750634145 scopus 로고    scopus 로고
    • Comparison between phytoestrogens and estradiol in the prevention of atheroma in ovariectomized cholesterol-fed rabbits [J]
    • Haines C, James A, Sahota D, et al. Comparison between phytoestrogens and estradiol in the prevention of atheroma in ovariectomized cholesterol-fed rabbits [J]. Climacteric 2006, 9(6):430-436.
    • (2006) Climacteric , vol.9 , Issue.6 , pp. 430-436
    • Haines, C.1    James, A.2    Sahota, D.3
  • 24
    • 0034283535 scopus 로고    scopus 로고
    • The effects of dietary supplementation with isoflavones from red clover on the lipoprotein profiles of post menopausal women with mild to moderate hypercholesterolaemia [J]
    • Howes JB, Sullivan D, Lai N, et al. The effects of dietary supplementation with isoflavones from red clover on the lipoprotein profiles of post menopausal women with mild to moderate hypercholesterolaemia [J]. Atherosclerosis 2000, 152(1):143-147.
    • (2000) Atherosclerosis , vol.152 , Issue.1 , pp. 143-147
    • Howes, J.B.1    Sullivan, D.2    Lai, N.3
  • 25
    • 38349000628 scopus 로고    scopus 로고
    • Cancer chemoprevention through dietary antioxidants: progress and promise [J]
    • Khan N, Afaq F, Mukhtar H Cancer chemoprevention through dietary antioxidants: progress and promise [J]. Antioxid Redox Signal 2008, 10(3):475-510.
    • (2008) Antioxid Redox Signal , vol.10 , Issue.3 , pp. 475-510
    • Khan, N.1    Afaq, F.2    Mukhtar, H.3
  • 26
    • 0035863857 scopus 로고    scopus 로고
    • Different effects of genistein and resveratrol on oxidative DNA damage in vitro [J]
    • Win W, Cao Z, Peng X, et al. Different effects of genistein and resveratrol on oxidative DNA damage in vitro [J]. Mutat Res 2002, 513(1-2):113-120.
    • (2002) Mutat Res , vol.513 , Issue.1-2 , pp. 113-120
    • Win, W.1    Cao, Z.2    Peng, X.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.