Efficacy and safety of AM-101 in the treatment of acute inner ear tinnitus - A double-blind, randomized, placebo-controlled phase II study

Otology and Neurotology

Volumn 35, Issue 4, 2014, Pages 589-597

  Van De Heyning, Paul ^a   Muehlmeier, Guido ^b   Cox, Tony ^c   Lisowska, Grazyna ^d   Maier, Heinz ^a   Morawski, Krzysztof ^e   Meyer, Thomas ^f  

^a ANTWERP UNIVERSITY HOSPITAL   (Belgium)

^b BUNDESWEHRKRANKENHAUS ULM   (Germany)

^c VIRGA JESSE HOSPITAL   (Belgium)

^d MEDICAL UNIVERSITY OF SILESIA   (Poland)

^e MEDICAL UNIVERSITY OF WARSAW   (Poland)

^f Auris Medical AG   (Switzerland)

Author keywords

Acute acoustic trauma; Cochlea; Idiopathic sudden sensorineural hearing loss; Intratympanic; Otitis Media; Therapy; Tinnitus

Indexed keywords

AMINO ACID RECEPTOR BLOCKING AGENT; INTERLEUKIN 1BETA; KETAMINE;

ADOLESCENT; ADULT; AGED; ANALYSIS OF VARIANCE; ARTICLE; AUDITORY THRESHOLD; COCHLEA FENESTRA; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; EUROPE; FEMALE; FOLLOW UP; HEMISPHERIC DOMINANCE; HUMAN; INJECTION; INNER EAR DISEASE; MALE; METABOLISM; MIDDLE AGED; MIDDLE EAR; MULTICENTER STUDY; OTITIS MEDIA; PHASE 2 CLINICAL TRIAL; PHYSIOLOGY; PSYCHOLOGICAL ASPECT; PURE TONE AUDIOMETRY; RANDOMIZED CONTROLLED TRIAL; STATISTICAL ANALYSIS; TINNITUS; TREATMENT OUTCOME; YOUNG ADULT;

ADOLESCENT; ADULT; AGED; ANALYSIS OF VARIANCE; AUDIOMETRY, PURE-TONE; AUDITORY THRESHOLD; DATA INTERPRETATION, STATISTICAL; EAR, MIDDLE; EUROPE; EXCITATORY AMINO ACID ANTAGONISTS; FEMALE; FOLLOW-UP STUDIES; FUNCTIONAL LATERALITY; HUMANS; INJECTIONS; INTERLEUKIN-1BETA; KETAMINE; LABYRINTH DISEASES; MALE; MIDDLE AGED; OTITIS MEDIA; ROUND WINDOW, EAR; TINNITUS; TREATMENT OUTCOME; YOUNG ADULT;

EID: 84897078493     PISSN: 15317129     EISSN: 15374505     Source Type: Journal    
DOI: 10.1097/MAO.0000000000000268     Document Type: Article

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